A. Friberg

发表

Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.

Brian A. Chauder, E. Olejniczak, S. Fesik, 2013, Journal of medicinal chemistry.

Studying weak and dynamic interactions of posttranslationally modified proteins using expressed protein ligation.

M. Sattler, C. Becker, K. Tripsianes, 2014, ACS chemical biology.

Structure and molecular recognition of proteins linked to pre-mRNA splicing and transcriptional regulation

A. Friberg, 2010 .

The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies

Sven Christian, D. Scadden, A. Haegebarth, 2019, Leukemia.

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods.

E. Olejniczak, S. Fesik, O. Rossanese, 2016, Journal of medicinal chemistry.

Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069

Lindsay C. Westlake, M. Meyerson, A. Cherniack, 2022, Journal of medicinal chemistry.

Abstract 2: Discovery of BAY 2402234 by phenotypic screening: A human Dihydroorotate Dehydrogenase (DHODH) inhibitor in clinical trials for the treatment of myeloid malignancies

Sven Christian, D. Scadden, A. Haegebarth, 2019, Cancer Chemistry.

The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation

B. Kempkes, M. Sattler, J. Hennig, 2015, PLoS pathogens.

Structure and ligand binding of the extended Tudor domain of D. melanogaster Tudor-SN.

M. Sattler, A. Friberg, A. Mourão, 2009, Journal of molecular biology.

Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C

Clara D. Christ, P. Steigemann, H. Briem, 2020, ChemMedChem.

Structure of an atypical Tudor domain in the Drosophila Polycomblike protein

M. Sattler, Jürg Müller, A. Friberg, 2010, Protein science : a publication of the Protein Society.

Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A

M. Quanz, A. Friberg, I. Heisler, 2020, ACS omega.

A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand

E. Olejniczak, S. Fesik, A. Friberg, 2014, Journal of Biomolecular NMR.

Strategies for the structural analysis of multi-protein complexes: lessons from the 3D-Repertoire project.

B. Séraphin, M. Graille, H. van Tilbeurgh, 2011, Journal of structural biology.

Oral disinfectants inhibit protein-protein interactions mediated by the anti-apoptotic protein Bcl-xL and induce apoptosis in human oral tumor cells.

M. Sattler, Bianca Sperl, T. Berg, 2013, Angewandte Chemie.

A Novel Protein-Protein Interaction in the RES (REtention and Splicing) Complex*

B. Séraphin, H. van Tilbeurgh, M. Sattler, 2014, The Journal of Biological Chemistry.

A method for the second-site screening of K-Ras in the presence of a covalently attached first-site ligand

E. Olejniczak, S. Fesik, A. Friberg, 2014, Journal of Biomolecular NMR.

Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design.

Anders Friberg, Bin Zhao, E. Olejniczak, 2015, Journal of medicinal chemistry.

Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”

Lindsay C. Westlake, M. Meyerson, A. Cherniack, 2022, Journal of medicinal chemistry.

Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists.

P. Lienau, E. Pook, Jonathan T. Goldstein, 2022, Bioorganic & medicinal chemistry.