R. Daniels

发表

Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design.

Brian A. Chauder, E. Olejniczak, S. Fesik, 2013, Journal of medicinal chemistry.

Application of combinatorial chemistry science on modern drug discovery.

Craig W Lindsley, J. P. Kennedy, C. Lindsley, 2008, Journal of combinatorial chemistry.

Microwave-assisted protocols for the expedited synthesis of pyrazolo[1,5-a] and [3,4-d]pyrimidines

C. Lindsley, E. Lebois, R. Daniels, 2008 .

Progress toward the total synthesis of lucentamycin A: total synthesis and biological evaluation of 8-epi-lucentamycin A.

Bruce J. Melancon, L. Marnett, C. Lindsley, 2009, The Journal of organic chemistry.

Total synthesis of polemannones B and C

C. Lindsley, R. Daniels, O. Fadeyi, 2009 .

Total synthesis of Ciliatamides A-C: stereochemical revision and the natural product-guided synthesis of unnatural analogs.

C. Lindsley, Jana A. Lewis, R. Daniels, 2008, Organic letters.

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

R. Daniels, Klarissa D Jackson, J. A. Perkins, 2018, Chemical research in toxicology.

Synthesis and SAR of N-(4-(4-alklylpiperazin-1-yl)phenyl)benzamides as muscarinic acetylcholine receptor subtype 1 (M1) anatgonists.

C. Lindsley, P. Conn, R. Daniels, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of analogs of the M1 allosteric agonist TBPB. Part II: Amides, sulfonamides and ureas--the effect of capping the distal basic piperidine nitrogen.

C. Lindsley, P. Conn, R. Daniels, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties.

J. P. Kennedy, C. Lindsley, P. Conn, 2008, Bioorganic & medicinal chemistry letters.

Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling.

S. Fesik, A. Waterson, O. Rossanese, 2018, Journal of medicinal chemistry.

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

E. Olejniczak, S. Fesik, A. Waterson, 2014, Proceedings of the National Academy of Sciences.

In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.

C. Lindsley, C. Hopkins, J. Hao, 2010, ACS chemical biology.

Novel GlyT1 inhibitor chemotypes by scaffold hopping. Part 2: development of a [3.3.0]-based series and other piperidine bioisosteres.

D. Sheffler, C. Lindsley, P. Conn, 2014, Bioorganic & medicinal chemistry letters.

Progress toward the total synthesis of lucentamycin A: total synthesis and biological evaluation of 8-epi-lucentamycin A.

L. Marnett, C. Lindsley, R. Daniels, 2009, The Journal of organic chemistry.