S. Sohn

发表

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.

Adam R. Johnson, Jun Liang, J. DeVoss, 2013, Journal of medicinal chemistry.

Lead identification of novel and selective TYK2 inhibitors.

Adam R. Johnson, Jun Liang, M. Ultsch, 2013, European journal of medicinal chemistry.

Requirement for p56lck tyrosine kinase activation in T cell receptor- mediated thymic selection

R. Perlmutter, S. Levin, T. Nakayama, 1996, The Journal of experimental medicine.

Lck activity controls CD4/CD8 T cell lineage commitment.

J. Alberola-Ila, E. Rothenberg, G. Hernández-Hoyos, 2000, Immunity.

Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein

H. Phee, S. Sohn, Songli Wang, 2019, Life Science Alliance.

A function of Fas-associated death domain protein in cell cycle progression localized to a single amino acid at its C-terminal region.

A. Winoto, Z. Hua, D. Cado, 2003, Immunity.

Apoptosis during negative selection of autoreactive thymocytes.

A. Winoto, S. Sohn, Jennifer D. Thompson, 2007, Current opinion in immunology.

Non‐redundant function of the MEK5–ERK5 pathway in thymocyte apoptosis

A. Winoto, S. Sohn, Gavin M. Lewis, 2008, The EMBO journal.

Activated p56lck Directs Maturation of Both CD4 and CD8 Single-Positive Thymocytes1

R. Perlmutter, K. Forbush, S. Sohn, 2001, The Journal of Immunology.

CD 4 and CD 8 Single-Positive Thymocytes Directs Maturation of Both lck Activated p 56

R. Perlmutter, K. Forbush, S. Sohn, 2001 .

Requirement for Jak3 in mature T cells: its role in regulation of T cell homeostasis.

R. Perlmutter, J. Ihle, K. Forbush, 1998, Journal of immunology.

Defining the Threshold IL-2 Signal Required for Induction of Selective Treg Cell Responses Using Engineered IL-2 Muteins

D. Bates, Jiamiao Lu, Min-Zu Wu, 2020, Frontiers in Immunology.

Constitutive Phosphorylation Mutation in Fas-associated Death Domain (FADD) Results in Early Cell Cycle Defects*

A. Winoto, S. Sohn, Stephanie L Osborn, 2007, Journal of Biological Chemistry.

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model.

Adam R. Johnson, Jun Liang, J. DeVoss, 2017, Bioorganic & medicinal chemistry letters.

Revealed by Novel TYK2-Selective Inhibitors Activity in Human Cytokine Responses A Restricted Role for TYK2 Catalytic

Adam R. Johnson, N. Lewin-Koh, Lawren C. Wu, 2013 .

Emerging Therapeutics for Immune Tolerance: Tolerogenic Vaccines, T cell Therapy, and IL-2 Therapy

H. Phee, S. Sohn, Cody D. Moorman, 2021, Frontiers in Immunology.

A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors

Adam R. Johnson, Jun Liang, N. Lewin-Koh, 2013, The Journal of Immunology.

Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q

L. Honigberg, Ashley M. Smith, A. Phillips, 2011, PloS one.

Apoptosis during lymphoid development.

Arvind Rajpal, A. Rajpal, A. Winoto, 2003, Current opinion in immunology.

ERK5 MAPK Regulates Embryonic Angiogenesis and Acts as a Hypoxia-sensitive Repressor of Vascular Endothelial Growth Factor Expression*

A. Winoto, D. Cado, S. Sohn, 2002, The Journal of Biological Chemistry.

Transcriptional Regulation of Tissue-Specific Genes by the ERK5 Mitogen-Activated Protein Kinase

A. Winoto, S. Sohn, Linda K. Lee, 2005, Molecular and Cellular Biology.

Amg 592 Is an Investigational IL-2 Mutein That Induces Highly Selective Expansion of Regulatory T Cells

T. Yuraszeck, K. Park, S. Sohn, 2017 .

Requirement for p56lck tyrosine kinase activation in TCR-mediated thymic selection

S. Levin, S. Sohn, Tomoya Nakayama, 1997 .

Mitogen-activated Protein Kinase Tissue-specific Genes by the Erk5 Transcriptional Regulation Of

A. Winoto, S. Sohn, Linda K. Lee, 2005 .