R. Hirschmann

发表

A new class of angiotensin-converting enzyme inhibitors

C. A. Stone, W. Greenlee, E. Thorsett, 1980, Nature.

The versatile steroid nucleus: Design and synthesis of a peptidomimetic employing this novel scaffold.

W. Shakespeare, R. Hirschmann, Amos B. Smith, 1993 .

Total synthesis of an enzyme. IV. Factors affecting the conversion of protected S-protein to ribonuclease S'

D. Veber, S. Varga, H. Joshua, 1969 .

The beta-D-glucose scaffold as a beta-turn mimetic.

K. Nicolaou, Amos B. Smith, R. Hirschmann, 2009, Accounts of chemical research.

Conformationally restricted bicyclic analogs of somatostatin.

S J Bergstrand, D. Veber, R. Nutt, 1978, Proceedings of the National Academy of Sciences of the United States of America.

A potent cyclic hexapeptide analogue of somatostatin

Ruth F. Nutt, Roger M. Freidinger, Ralph Hirschmann, 1981, Nature.

APPROACHES TO VASODILATING/β-ADRENERGIC BLOCKING AGENTS: EXAMPLES OF THE DIHYDROLUTIDINE TYPE

G. Ponticello, J. Baldwin, E. Engelhardt, 1981 .

Medicinal Chemistry in the Golden Age of Biology: Lessons from Steroid and Peptide Research

R. Hirschmann, 1991 .

Design, synthesis, and crystal structure of a pyrrolinone-based peptidomimetic possessing the conformation of a .beta.-strand: potential application to the design of novel inhibitors of proteolytic enzymes

Ralph Hirschmann, John L. Wood, P. Carroll, 1992 .

Nonpeptidal peptidomimetics with a β-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist

Ralph Hirschmann, J. Salvino, C. Donaldson, 1992 .

Design, Synthesis, and Crystal Structure of a Pyrrolinone-Based Peptidomimetic Possessing the Conformation of a β-Strand: Potential Application to the Design of Novel Inhibitors of Proteolytic Enzymes

P. Carroll, R. Hirschmann, J. L. Wood, 1993 .

De Novo Design and Synthesis of Somatostatin Non‐Peptide Peptidomimetics Utilizing β‐D‐Glucose as a Novel Scaffolding.

C. Donaldson, C. Strader, R. Freidinger, 1994 .

Synthesis of potent cyclic hexapeptide NK-1 antagonists. Use of a minilibrary in transforming a peptidal somatostatin receptor ligand into an NK-1 receptor ligand via a polyvalent peptidomimetic.

A B Smith, C. Strader, M. Cichy-Knight, 1996, Journal of medicinal chemistry.

Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis.

A B Smith, M. Cichy-Knight, W. Shakespeare, 1998, Journal of medicinal chemistry.

Synthesis of a substance P antagonist with a somatostatin scaffold: factors affecting agonism/antagonism at GPCRs and the role of pseudosymmetry.

D. Underwood, R. Hirschmann, A. Smith, 2000, Journal of Medicinal Chemistry.

Effects of heterocyclic aromatic substituents on binding affinities at two distinct sites of somatostatin receptors. Correlation with the electrostatic potential of the substituents.

D. Underwood, Amos B. Smith, R. Hirschmann, 2003, Journal of medicinal chemistry.

Design, Synthesis, and Solution Structure of a Pyrrolinone-Based β-Turn Peptidomimetic

Ralph Hirschmann, R. Hirschmann, Amos B. Smith, 2000 .

Design and synthesis of potent cystine-free cyclic hexapeptide agonists at the human urotensin receptor.

Ralph Hirschmann, Wen-Long Chen, R. Hirschmann, 2006, Organic letters.

Photochemistry of Biologically Important Transition Metal Complexes. I. Cyanocobalamin and Related Corrin Complexes of Rhodium(III)

R. Hirschmann, A. Vogler, H. Kunkely, 1976 .

1.01 – Reflections of a Medicinal Chemist: Formative Years through Thirty-Seven Years Service in the Pharmaceutical Industry

R. Emerson, R. Hirschmann, 2007 .

Lactam restriction of peptide conformation in cyclic hexapeptides which alter rumen fermentation.

D. Veber, R. Freidinger, R. Hirschmann, 2009, International journal of peptide and protein research.

REARRANGEMENT OF THE STEROID C/D RINGS. SYNTHESIS OF AN 11-KETO-Δ13(17a)-C-NOR/D-HOMO-STEROID

R. Hirschmann, C. F. Hiskey, N. Wendler, 1953 .

The cortisone era: aspects of its impact. Some contributions of the Merck Laboratories

R. Hirschmann, 1992, Steroids.

Synthesis of a proposed growth hormone releasing factor.

D. Veber, R. Hirschmann, J. Milkowski, 1971, Biochemical and biophysical research communications.

Design and synthesis of sulfur-free cyclic hexapeptides which contain the RGD sequence and bind to the fibrinogen GP IIb/IIIa receptor. A conformation-based correlation between propensity for imide formation and receptor affinity.

A. Lender, R. Hirschmann, W. Yao, 2009, International journal of peptide and protein research.

Novel ligands lacking a positive charge for the δ- and μ-opioid receptors

Amos B. Smith, P. Schiller, C. Lemieux, 2000 .

Intramolecular hydrogen-bond participation in phosphonylammonium salt formation.

R. Hirschmann, A. Smith, L. Ducry, 2000, Organic letters.

Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics.

R. Hirschmann, Amos B. Smith, O. Kikuchi, 2005, Organic letters.

Design and synthesis of novel scaffolds for drug discovery: hybrids of beta-D-glucose with 1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-one, the corresponding 1-oxazepine, and 2- and 4-pyridyldiazepines.

R. Hirschmann, A. Smith, J. Hynes, 2001, Organic letters.

Acetamidomethyl. A novel thiol protecting group for cysteine.

D. Veber, S. Varga, R. Hirschmann, 1972, Journal of the American Chemical Society.

Pyrrolinone-based peptidomimetics. "Let the enzyme or receptor be the judge".

R. Hirschmann, Amos B. Smith, A. Charnley, 2011, Accounts of chemical research.

Design, synthesis, and evaluation of azepine-based cryptophycin mimetics

Y. Cho, R. Hirschmann, Amos B. Smith, 2003 .

SYNTHESIS OF THE FIRST TRICYCLIC HOMODETIC PEPTIDE. USE OF COORDINATED ORTHOGONAL DEPROTECTION TO ACHIEVE DIRECTED RING CLOSURE

B. Arison, R. Hirschmann, W. Yao, 1998 .

Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 1. From nonpeptide peptidomimetics to nanotubes.

P. Carroll, R. Hirschmann, Amos B. Smith, 2010, Organic letters.

Investigations of an Antibody Ligase

S. Benkovic, Carol M. Taylor, J. Witherington, 1997 .

The carboxyl terminus heptapeptide of the R2 subunit of mammalian ribonucleotide reductase inhibits enzyme activity and can be used to purify the R1 subunit

B. Cooperman, H. Rubin, R. Hirschmann, 1990, FEBS letters.

Somatostatin analogs which define the role of the lysine-9 amino group.

D. Veber, R. Nutt, R. Hirschmann, 2009, International journal of peptide and protein research.

Tactics for Minimal Protection in Peptide Synthesis

D. Veber, R. Hirschmann, 1973 .

Catechol: A minimal scaffold for non-peptide peptidomimetics of the i + 1 and i + 2 positions of the beta-turn of somatostatin.

Amos B. Smith, R. Hirschmann, A. Angeles, 2006, Organic letters.

SYMBIOTIC APPROACH TO DRUG DESIGN: ANTIHYPERTENSIVE β-ADRENERGIC BLOCKING AGENTS

G. F. Lundell, G. Ponticello, J. Baldwin, 1980 .

Controlled synthesis of peptides in aqueous medium. VIII. Preparation and use of novel .alpha.-amino acid N-carboxyanhydrides

D. Veber, V. Garsky, S. Miller, 1971 .

Novel chimeric scaffolds to extend the exploration of receptor space: hybrid beta-D-glucose-benzoheterodiazepine structures for broad screening. Effect of amide alkylation on the course of cyclization reactions.

R. Hirschmann, Amos B. Smith, J. Hynes, 2004, The Journal of organic chemistry.

The versatile steroid nucleus: Design and synthesis of a peptidomimetic employing this novel scaffold.

W. Shakespeare, R. Hirschmann, Amos B. Smith, 1993 .

The Reaction of Epoxides with Anhydrous Hydrogen Fluoride in the Presence of Organic Bases. The Preparation of 9α-Fluoro-4-pregnene-11β,17α,21-Triol 3,20-Dione 21-Acetate and Its 1-Dehydro Analog

J. W. Wood, R. Hirschmann, Richard J. Miller, 1956 .

Heterocyclic analogues of the antihypertensive beta-adrenergic blocking agent (S)-2-[3-(ter-butylamino)-2-hydroxypropoxy]-3-cyanopyridine.

G. Ponticello, J. Baldwin, E. Engelhardt, 1980, Journal of medicinal chemistry.

Titanium(III) as a selective reducing agent for nitroarginyl peptides: synthesis of arginine vasotocin

D. Veber, R. Freidinger, R. Hirschmann, 1978 .

Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.

S. Benkovic, Carol M. Taylor, R. Hirschmann, 1994, Science.

Synthesis of 2'-(2,4-Difluorophenyl)-11β,17,21-trihydroxy-6,16α-dimethyl-20- oxopregna-4,6-dieno[3,2-c]pyrazole

M. Tishler, R. Hirschmann, R. Strachan, 1964 .

SYNTHESIS OF PREGN-4-ENO(3,2-C)PYRAZOLES RELATED TO 9-ALPHA-FLUORO-16-ALPHA-METHYLCORTISOL.

M. Tishler, R. Hirschmann, W. J. Paleveda, 1964, Journal of medicinal chemistry.

Synthesis and Structure of Steroidal Pregn-4-eno- and 5α-Pregnano [3,2-c]pyrazoles. A Novel Class of Potent Anti-Inflammatory Steroids

M. Tishler, R. Hirschmann, J. Fried, 1964 .

Synthesis and Structure of Steroidal 4-Pregneno [3,2-c]Pyrazoles. A Novel Class of Potent Anti-Inflammatory Steroids

M. Tishler, R. Hirschmann, J. Fried, 1963 .

Inhibitors of gastric acid secretion: antisecretory 2-pyridylurea derivatives.

C. N. Habecker, A. Deana, R. Hirschmann, 1983, Journal of medicinal chemistry.

Peptide bond formation via catalytic antibodies: Synthesis of a novel phosphonate diester hapten

S. Benkovic, Carol M. Taylor, R. Hirschmann, 1994 .

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors.

Louis-David Cantin, Lawrence C Kuo, Ralph Hirschmann, 2003, Journal of medicinal chemistry.

Pyrrolinone-Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport

P. Darke, W. Schleif, E. Emini, 1995 .

Enantioretentive alkylation of oxazolidinone aluminum enolates with epoxides: Preparation of uncoded homoserine analogs

R. Hirschmann, Amos B. Smith, A. Pasternak, 1994 .

Molecular modeling, synthesis, and structures of N-methylated 3,5-linked pyrrolin-4-ones toward the creation of a privileged nonpeptide scaffold.

P. Carroll, R. Hirschmann, P. Sprengeler, 1999, Bioorganic & medicinal chemistry.

Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy: Identification of Pyrophosphonate Anhydrides and Highly Reactive Phosphonylammonium Salts1

Carol M. Taylor, J. Witherington, R. Hirschmann, 1997 .

De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing beta-D-glucose as a novel scaffolding

Joseph M. Salvino, Ralph Hirschmann, K. Nicolaou, 1993 .

Azide and Cyanide Displacements via Hypervalent Silicate Intermediates.

R. Hirschmann, Amos B. Smith, P. DeShong, 1999, The Journal of organic chemistry.

Synthesis and antihypertensive activity of some ester progenitors of methyldopa.

W. Randall, E. Engelhardt, R. Hirschmann, 1978, Journal of medicinal chemistry.

Synthesis of polypyrrolinones on solid support.

A B Smith, R. Hirschmann, R Hirschmann, 2000, Organic letters.

A second-generation synthesis of polypyrrolinone nonpeptidomimetics: prelude to the synthesis of polypyrrolinones on solid support.

R. Hirschmann, A. Smith, H. Liu, 2000, Organic letters.

The Partial Synthesis of 12α-Methyl-11-dehydrocorticosterone

B. Arison, R. Hirschmann, R. Strachan, 1960 .

The Rearrangement of the Steroid C/D Rings1

R. Hirschmann, C. F. Hiskey, N. Wendler, 1954 .

The Structure of the Enol Acetate Derivatives of Steroid 7- and 11-Ketones

R. Hirschmann, N. Wendler, 1953 .

Development of an efficient, regio- and stereoselective route to libraries based on the beta-D-glucose scaffold.

R. Hirschmann, A. Smith, L. Ducry, 2000, The Journal of organic chemistry.

The first synthesis of a tricyclic homodetic peptide employing coordinated orthogonal protection

B. Arison, R. Hirschmann, W. Yao, 1996 .

Chemoselective monoalkylation of 5-trifluoroacetamido- and 5-acetamido-1-pentanol derivatives via N,O-bisdeprotonation. Quantitation of evolved H2 as a probe of anion formation

R. Hirschmann, Amos B. Smith, P. G. Spoors, 1995 .

Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase.

B. Cooperman, R. Hirschmann, J. Barbosa, 1998, Bioorganic & medicinal chemistry letters.

A New Route to 2-Amino-2-deoxy-β-D-glucosides

W. V. Ruyle, R. Hirschmann, R. Strachan, 1966 .

Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P2' side chains.

L. Kuo, W. Schleif, S. Munshi, 2006, Bioorganic & medicinal chemistry letters.

Cyclic peptide formation catalyzed by an antibody ligase.

S. Benkovic, J. Liu, S. Iwama, 2000, Proceedings of the National Academy of Sciences of the United States of America.

PHOSPHONYLTRIETHYLAMMONIUM SALTS : NOVEL REACTIVE SPECIES FOR THE SYNTHESIS OF PHOSPHONATE ESTERS AND PHOSPHONONAMIDES

Carol M. Taylor, J. Witherington, R. Hirschmann, 1995 .

Synthesis of peptides in aqueous medium. VI. Synthesis of an unsymmetrical cystine peptide fragment of insulin

D. Veber, R. Hirschmann, R. G. Denkewalter, 1969 .

The controlled synthesis of peptides in aqueous medium. 3. Use of Leuchs' anhydrides in the synthesis of dipeptides. Mechanism and control of side reactions.

D. Veber, H. Joshua, R. Hirschmann, 1967, The Journal of organic chemistry.

Piperazinylpyrazines with central serotoninmimetic activity.

C. A. Stone, E. Engelhardt, R. Hirschmann, 1978, Journal of medicinal chemistry.

De Novo Design, Synthesis, and X-ray Crystal Structures of Pyrrolinone-Based .beta.-Strand Peptidomimetics

Ralph Hirschmann, John L. Wood, P. Carroll, 1994 .

A practical synthesis of Nalpha-Fmoc-L-pyrazinylalanine via Schöllkopf's chiral auxiliary.

R. Hirschmann, E. Thornton, A. Smith, 2008, The journal of peptide research : official journal of the American Peptide Society.

The first design and synthesis of a steroidal peptidomimetic. The potential value of peptidomimetics in elucidating the bioactive conformation of peptide ligands

W. Shakespeare, R. Hirschmann, Amos B. Smith, 1992 .

Studies on the total synthesis of an enzyme. II. Synthesis of a protected tetratetracontapeptide corresponding to the 21-64 sequence of ribonuclease A.

D. Veber, V. Garsky, R. Nutt, 1969, Journal of the American Chemical Society.

Purification and characterization of human liver glycolate oxidase. Molecular weight, subunit, and kinetic properties.

W. Randall, R. Hirschmann, H. Schwam, 1979, Biochemistry.

Symbiotic approach to drug design: antihypertensive beta-adrenergic blocking agents.

G. F. Lundell, G. Ponticello, J. Baldwin, 1979, Journal of medicinal chemistry.

Dihydrofolate reductase: the amino acid sequence of the enzyme from a methotrexate-resistant mutant of Escherichia coli.

R. Hirschmann, J. Sondey, J. Rodkey, 1978, Biochemistry.

Efficacy of water-soluble derivatives of vitamin K1 in counteracting drug-induced hypoprothrombinemia.

R. Hirschmann, C. W. Mushett, K. Kelley, 1959, Blood.

The Synthesis of Vitamin K11

R. Hirschmann, Richard J. Miller, N. Wendler, 1954 .

The synthesis of peptides in aqueous medium. VII. The preparation and use of 2,5-thiazolidinediones in peptide synthesis.

D. Veber, B. Arison, H. Joshua, 1971, The Journal of organic chemistry.

Synthesis of peptides in aqueous medium. V. Preparation and use of 2,5-thiazolidinediones (NTA's). Use of the 13C-H nuclear magnetic resonance signal as internal standard for quantitative studies.

D. Veber, B. Arison, H. Joshua, 1968, Journal of the American Chemical Society.

Design and Synthesis of a Competent Pyrrolinone−Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1

R. Campbell, Z. Nagy, D. Bolin, 1999 .

Configurational Relationship of 11,12-Oxygenated Sapogenins. Rearrangement to the [3.3.0]Bicycloöctane System1

R. Hirschmann, N. Wendler, H. L. Slates, 1955 .

Design, synthesis, and evaluation of a pyrrolinone-based matrix metalloprotease inhibitor.

R. Hirschmann, J. Duan, P. Sprengeler, 2000, Organic letters.

Synthesis of thyrotropin-releasing hormone analogues with selective central nervous system effects.

D. Veber, R. Nutt, B. Arison, 1981, Journal of medicinal chemistry.

A General Synthesis of 4,5-Unsaturated 2-Oxasteroids. A Synthesis of 2-Oxacortisol

R. Hirschmann, R. Walker, N. Steinberg, 1962 .

A versatile, efficient synthesis of (−)-(2S, 3R, 4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-methylheptane, the abbott pseudodipeptidyl insert

R. Hirschmann, Amos B. Smith, David R. Jones, 1990 .

An effective synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones

R. Hirschmann, Amos B. Smith, P. Sprengeler, 1993 .

Synthesis and Properties of 4-Methyl-2-oxo-1,2-benzopyran-7-yl β-D-Galactoside (Galactoside of 4-Methylumbelliferone)

J. W. Wood, R. Hirschmann, R. Strachan, 1962 .

16-Methylated Steroids. IV. 6,16α-Dimethyl-▵6-Hydrocortisone and Related Compounds

H. Mrozik, M. Tishler, R. Hirschmann, 1963 .

The design and synthesis of 2,5-linked pyrrolinones. A potential non-peptide peptidomimetic scaffold.

A B Smith, R. Hirschmann, P. Sprengeler, 1996, Bioorganic & medicinal chemistry.

The synthesis of peptides in aqueous medium. IV. A novel protecting group for cysteine.

D. Veber, R. Hirschmann, J. Milkowski, 1968, Tetrahedron letters.

The synthesis of an enzyme.

R. Hirschmann, R. Denkewalter, 1970, Die Naturwissenschaften.

Synthesis of alpha-methyl-DLg-glutathione.

D. Veber, R. Hirschmann, K. Pfister, 1967, Journal of Medicinal Chemistry.

The Controlled Synthesis of Peptides in Aqueous Medium. I. The Use of α-Amino Acid N-Carboxyanhydrides

D. Veber, R. Hirschmann, H. Schwam, 1966 .

Studies on the total synthesis of an enzyme. V. The preparation of enzymatically active material.

D. Veber, R. Nutt, F. W. Holly, 1969, Journal of the American Chemical Society.

Studies on the total synthesis of an enzyme. I. Objective and strategy.

D. Veber, F. W. Holly, R. Hirschmann, 1969, Journal of the American Chemical Society.

First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues.

R. Hirschmann, A. Smith, G. Pettit, 2001, Organic letters.

Transport Characteristics of Peptidomimetics. Effect of the Pyrrolinone Bioisostere on Transport Across Caco-2 Cell Monolayers

R. Borchardt, M. Sudoh, Amos B. Smith, 1998, Pharmaceutical Research.

Synthesis and binding affinities of novel SRIF-mimicking beta-D-glucosides satisfying the requirement for a pi-cloud at C1.

R. Hirschmann, Amos B. Smith, E. Thornton, 2005, Organic letters.

Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2-receptor antagonists.

B. T. Phillips, P. Anderson, J. Hirshfield, 1982, Journal of medicinal chemistry.

A NEW BIOLOGICALLY POTENT STEROID: 1-DEHYDRO-9α-FLUOROHYDROCORTISONE ACETATE

M. Tishler, R. Hirschmann, R. Beyler, 1955 .

Investigation of an antibody-ligase. Evidence for strain-induced catalysis.

S. Benkovic, S. Savinov, R. Hirschmann, 2003, Bioorganic & medicinal chemistry letters.

Novel ligands lacking a positive charge for the delta- and mu-opioid receptors.

P. Schiller, C. Lemieux, N. N. Chung, 2000, Journal of medicinal chemistry.

The microbial 1-dehydrogenation of some delta4-3 ketosteroids.

R. Hirschmann, T. Stoudt, W. Mcaleer, 1955, Archives of biochemistry and biophysics.

Design and synthesis of peptidomimetic inhibitors of HIV-1 protease and renin. Evidence for improved transport.

P. Darke, E. Emini, R. Hirschmann, 1994, Journal of medicinal chemistry.

A Partial Synthesis of 11β,17α,21-Trihydroxy-A-nor-3(5)-pregnene-2,20-dione, an A-Nor Homolog of Hydrocortisone

R. Hirschmann, R. Walker, M. ChemerdaJohn, 1959 .

SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY OF SOME ESTER PROGENITORS OF METHYLDOPA

W. Randall, E. Engelhardt, R. Hirschmann, 1978 .

beta-Adrenergic blocking agents with acute antihypertensive activity.

G. F. Lundell, G. Ponticello, J. Baldwin, 1979, Journal of medicinal chemistry.

On the low energy solution conformation of somatostatin.

D. Veber, S. Brady, B. Arison, 1981, Biochemical and biophysical research communications.

Synthesis of novel, highly potent cyclic-hexapeptide analogs of somatostatin. Potential application of orthogonal protection for affinity chromatography

R. Nutt, T. Reisine, R. Hirschmann, 1991 .

Design and synthesis of nonpeptide peptidomimetic inhibitors of renin

M. Holloway, R. Hirschmann, Amos B. Smith, 1995, Biopolymers.

A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains

R. Hirschmann, Amos B. Smith, P. Sprengeler, 1997 .

Characterization of synthetic parathyroid hormone analogs and of synthetic by-products

R. Nutt, Jack L. Smith, L. Caporale, 1989 .

Isonicotinyloxycarbonyl, a novel amino protecting group for peptide synthesis.

D. Veber, R. Hirschmann, Y. C. Lee, 1977, The Journal of organic chemistry.

ISONICOTINYLOXYCARBONYL A NOVEL AMINO PROTECTING GROUP FOR PEPTIDE SYNTHESIS

D. Veber, R. Hirschmann, Y. C. Lee, 1978 .

The β‐D‐Glucose Scaffold as a β‐Turn Mimetic

K. Nicolaou, R. Hirschmann, Amos B. Smith, 2010 .

CONFIGURATION AT C12 OF 12-HYDROXYLATED SAPOGENINS. REARRANGEMENT OF THE STEROID C/D RINGS

R. Hirschmann, L. WendlerNorman, C. Snoddy, 1952 .

A CONTRIBUTION TO THE CHEMISTRY OF STEROID 17,21-OXIDES

R. Hirschmann, G. I. Poos, R. Walker, 1956 .

DESIGN, SYNTHESIS, AND EVALUATION OF A PYRROLINONE-PEPTIDE HYBRID LIGAND FOR THE CLASS II MHC PROTEIN HLA-DR1

R. Campbell, Z. Nagy, D. Bolin, 1998 .

Design, Synthesis, and Evaluation of a Pyrrolinone—Peptide Hybrid Ligand for the Class II MHC Protein HLA-DR1

R. Hirschmann, Amos B. Smith, A. L. A. L. E. Et, 1999 .

SYNTHESIS OF INDOMETHACIN METABOLITES.

W. V. Ruyle, R. Hirschmann, R. Strachan, 1964, Journal of medicinal chemistry.

A deuterium isotope effect on the inhibition of gastric secretion by N,N-dimethyl-N'-[2-(diisopropylamino)ethyl]-N'-(4,6-dimethyl-2-pyridyl)urea. Synthesis of metabolites.

C. N. Habecker, R. Hirschmann, J. Hoffman, 1983, Journal of medicinal chemistry.

Inferences about the conformation of somatostatin at a biologic receptor based on NMR studies

D. Veber, B. Arison, R. Hirschmann, 1978 .

Nonreducible cyclic analogues of somatostatin

D. Veber, F. W. Holly, R. Hirschmann, 1976 .