A. Aubertin

发表

A new series of pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors.

C. Nguyen, M. Andreola, V. Dollé, 1995, Journal of medicinal chemistry.

Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors.

C. Nguyen, M. Andreola, V. Dollé, 2000, Journal of medicinal chemistry.

Dendritic Catanionic Assemblies: In vitro Anti‐HIV Activity of Phosphorus‐Containing Dendrimers Bearing Galβ1cer Analogues

A. Caminade, J. Majoral, I. Rico-Lattes, 2005, Chembiochem : a European journal of chemical biology.

Design, Synthesis and Antiviral Activity of New Pyridinone Derivatives

R. Bureau, A. Aubertin, A. Kirn, 1997 .

Bicyclic imidazo derivatives, a new class of highly selective inhibitors for the human immunodeficiency virus type 1.

A. Aubertin, A. Kirn, C. Moog, 1994, Antiviral research.

Cytotoxic T lymphocyte response against multiple simian immunodeficiency virusA (SIV) proteins in SIV-infected macaques.

M. Kieny, J. Levy, A. Aubertin, 1992, Journal of immunology.

Rapid access to acyclic nucleosides via conjugate addition

F. Huet, A. Aubertin, N. Bourgougnon, 2003 .

Detection of Human Immunodeficiency Virus Type 1 Nef and CD4 Physical Interaction in Living Human Cells by Using Bioluminescence Resonance Energy Transfer

J. Galzi, M. Erhardt, C. Bertsch, 2005, Journal of Virology.

Synthesis and Antiviral Evaluation of D4T Analogues with a Spacer Arm Between Glucidic and Base Moieties

P. Krausz, A. Aubertin, Vincent Roy, 2004 .

Efficient Synthesis of New Nucleoside Analogues with a Methylenecyclobutane Unit

F. Huet, A. Aubertin, N. Bourgougnon, 2006 .

Synthesis of prodrug-type anti-HIV agents conjugating a REVERSE transcriptase inhibitor to a HIV-1 integrase inhibitor by a spontaneously cleavable linker

Anh Vu, A. Aubertin, I. Zarafu, 2007, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and antiviral activity of ethidium-arginine conjugates directed against the TAR RNA of HIV-1.

C. Bailly, R. Terreux, D. Cabrol-Bass, 1999, Journal of medicinal chemistry.

Structural Variability of the Initiation Complex of HIV-1 Reverse Transcription*

C. Ehresmann, B. Ehresmann, Valérie Goldschmidt, 2004, Journal of Biological Chemistry.

Efficient inhibition of HIV-1 replication in human immature monocyte-derived dendritic cells by purified anti-HIV-1 IgG without induction of maturation.

S. Zolla-Pazner, A. Aubertin, C. Moog, 2006, Blood.

Hepatitis C virus structural proteins do not prevent human dendritic cell maturation.

J. Abraham, A. Bohbot, A. Aubertin, 2008, Gastroenterologie clinique et biologique.

Dendritic cell susceptibility to hepatitis C virus genotype 1 infection

A. Bohbot, A. Aubertin, M. Navas, 2002, Journal of medical virology.

Homophymine A, an anti-HIV cyclodepsipeptide from the sponge Homophymia sp.

V. Sepe, A. Zampella, M. Monti, 2008, The Journal of organic chemistry.

Stimulation of HIV-1 Replication in Immature Dendritic Cells in Contact with Primary CD4 T or B Lymphocytes

A. Aubertin, C. Moog, V. Holl, 2010, Journal of Virology.

Syntheses, biochemical and biological evaluation of staurosporine analogues from the microbial metabolite rebeccamycin.

D. Fabbro, C. Bailly, M. Sancelme, 1998, Bioorganic & medicinal chemistry.

Synthesis and anti-HIV activity of glucose-containing prodrugs derived from saquinavir, indinavir and nelfinavir.

P. Vierling, J. Greiner, A. Aubertin, 2001, Carbohydrate research.

Human and simian immunodeficiency viruses deregulate early hematopoiesis through a Nef/PPARgamma/STAT5 signaling pathway in macaques.

N. Déglon, I. Dusanter-Fourt, B. Maillère, 2008, The Journal of clinical investigation.

Synthesis and anti-retroviral activity of O,O'-bis(3'-azido-2',3'-dideoxythymidin-5'-yl) phosphoramidate derivatives.

J. Imbach, A. Aubertin, J. Girardet, 1999, Nucleosides & nucleotides.

Properties of a chimeric simian-human immunodeficiency virus expressing an hybrid HIV-1 Nef/SIVmac Nef protein

C. Bertsch, A. Aubertin, D. Cluet, 2002, Archives of Virology.

Implication of the C-terminal domain of nef protein in the reversion to pathogenicity of attenuated SIVmacBK28-41 in macaques.

Y. Rivière, A. Aubertin, A. Kirn, 2000, Virology.

Organization of RNA transcripts from a 7.8-kb region of the frog virus 3 genome.

A. Aubertin, A. Kirn, T. N. Tham, 1988, Virology.

Molecular cloning and physical and translational mapping of the frog virus 3 genome.

P. Mutin, A. Aubertin, T. N. Tham, 1988, Virology.

Mapping of the gene coding for the major late structural polypeptide on the frog virus 3 genome.

A. Aubertin, T. N. Tham, J. Mesnard, 1986, The Journal of general virology.

Thermosensitivity of frog virus 3 genome expression: defect in early transcription.

A. Aubertin, A. Kirn, L. Tondre, 1986, Virology.

Human immunodeficiency virus type 1 infection of human CD4-transgenic rabbits.

M. Mehtali, L. Houdebine, A. Aubertin, 1995, The Journal of general virology.

Oxysterols, but Not Cholesterol, Inhibit Human Immunodeficiency Virus Replication in Vitro

A. Aubertin, A. Kirn, C. Moog, 1998, Antiviral chemistry & chemotherapy.

Influence of a Cα-Substitution on the S-Pivaloyl-2-Thioethyl Chain on the Anti-HIV Activity and Stability of the Resulting Zidovudine Mononucleoside Phosphotriester

J. Imbach, A. Aubertin, S. Peyrottes, 2001, Antiviral chemistry & chemotherapy.

Tat-neutralizing versus Tat-protecting antibodies in rhesus macaques vaccinated with Tat peptides.

B. Roques, S. Muller, E. Moreau, 2005, Vaccine.

Protection of SIVmac-infected macaque monkeys against superinfection by a simian immunodeficiency virus expressing envelope glycoproteins of HIV type 1.

M. Kieny, M. Mehtali, A. Aubertin, 1997, AIDS research and human retroviruses.

Cloning, sequence analysis, and expression of the major capsid protein of the iridovirus frog virus 3.

A. Aubertin, V. G. Chinchar, G. Gentry, 1996, Virology.

Evaluation in rhesus macaques of Tat and rev-targeted immunization as a preventive vaccine against mucosal challenge with SHIV-BX08.

G. Sutter, B. Verrier, Y. Ataman-Onal, 2002, DNA and cell biology.

Peptide-poly(L-lysine citramide) conjugates and their in vitro anti-HIV behavior.

Michel Vert, M. Vert, Jean Martinez, 2009, Biomacromolecules.

HIV-1 Replication in Langerhans and Interstitial Dendritic Cells Is Inhibited by Neutralizing and Fc-Mediated Inhibitory Antibodies

A. Aubertin, C. Moog, V. Holl, 2010, Journal of Virology.

Protection of monkeys by a split vaccine against SIVmac depends upon biological properties of the challenge virus

H. Petry, W. Lüke, A. Aubertin, 1993, AIDS.

Limited viral spread and rapid immune response in lymph nodes of macaques inoculated with attenuated simian immunodeficiency virus.

L. Montagnier, A. Aubertin, L. Chakrabarti, 1995, Virology.

Regulation of Protein Synthesis in Frog Virus 3-Infected Cells

A. Aubertin, T. N. Tham, L. Tondre, 1990 .

Translation Regulation of Frog Virus 3

A. Aubertin, T. N. Tham, L. Tondre, 1989 .

Ultrastructural evidence of Human Immunodeficiency Virus (HIV-1) multiplication in cultured endothelial cells (EC) of the human hepatic sinusoid

D. Jaeck, A. Steffan, A. Aubertin, 1990 .

3′-Deoxy-3′-C-trifluoromethyl Nucleosides: Synthesis and Antiviral Evaluation

R. Plantier-Royon, A. Aubertin, A. Kirn, 1998 .

Sodium dodecyl sulfate-mediated transfer of electrophoretically separated DNA-binding proteins.

A. Aubertin, A. Kirn, G. Obert, 1983, Analytical biochemistry.

SYNTHESIS AND ANTI-HIV ACTIVITY OF [D4U]-[TROVIRDINE ANALOGUE] AND [D4T]-[TROVIRDINE ANALOGUE] HETERODIMERS AS INHIBITORS OF HIV-1 REVERSE TRANSCRIPTASE

A. Aubertin, A. Ciurea, C. Fossey, 2002, Nucleosides, nucleotides & nucleic acids.

Imidazo[1,5-g][1,4]diazepines, TIBO analogues lacking the phenyl ring: synthesis and evaluation as anti-HIV agents.

C. Monneret, D. Grierson, A. Aubertin, 1996 .

Synthesis of a new class of HIV-1 inhibitors.

C. Di Giorgio, A. Aubertin, A. Aumelas, 1999, Nucleosides & nucleotides.

Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro

R. Schinazi, J. Imbach, J. Sommadossi, 1994, Antimicrobial Agents and Chemotherapy.

Synthesis and Biological Activities of New Carbaacyclonucleosides and 1′-Oxaacyclonucleosides Related to Clitocine

A. Aubertin, R. Condom, N. Patino, 2000, Nucleosides, nucleotides & nucleic acids.

Structure and regulation of the immediate-early frog virus 3 gene that encodes ICR489

A. Aubertin, D. Willis, W. Beckman, 1988, Journal of virology.

Fate of frog virus 3 DNA replicated in the nucleus of arginine-deprived CHO cells.

J. Martín, A. Aubertin, A. Kirn, 1984, The Journal of general virology.

Intracellular distribution and phosphorylation of virus-induced polypeptides in frog virus 3-infected cells.

J. Martín, A. Aubertin, A. Kirn, 1981, Virology.

Proteins solubilized from frog virus 3 particles: effect on transcription

A. Aubertin, A. Kirn, C. Travo, 1976, Journal of virology.

Arginine requirement for frog virus 3 development.

A. Aubertin, 1975, Virology.

Proteins of a Polyhedral Cytoplasmic Deoxyvirus

P. Palese, R. Vilaginés, A. Aubertin, 1971, Journal of virology.

Effect of the Thioalkyl Chain Variation in the Efficiency of Sate Pronucleotides

J. Imbach, A. Aubertin, C. Périgaud, 1998 .

Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections.

F. Barré-Sinoussi, T. Idziorek, M. Mehtali, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Phenyl phosphotriester derivatives of AZT: variations upon the SATE moiety.

P. Augustijns, A. Aubertin, G. Coussot, 2008, Bioorganic & medicinal chemistry.

Primary cultures of endothelial cells from the human liver sinusoid are permissive for human immunodeficiency virus type 1.

D. Jaeck, A. Steffan, A. Aubertin, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Syntheses of new difluoromethylene benzoxazole and 1,2,4-oxadiazole derivatives, as potent non-nucleoside HIV-1 reverse transcriptase inhibitors

W. R. Dolbier, M. Médebielle, A. Aubertin, 2005 .

Anti-human immunodeficiency virus type 1 activities of dideoxynucleoside phosphotriester derivatives in primary monocytes/macrophages.

J. Imbach, A. Aubertin, A. Kirn, 1996, Research in virology.

Synthesis And Antiviral Evaluation Of 2′,3′-Secothymidine Analogs of ddT and AZT

J. Imbach, A. Aubertin, A. Kirn, 1991 .

Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate.

J. Imbach, A. Pompon, A. Aubertin, 1995, Journal of medicinal chemistry.

An original pronucleotide strategy for the simultaneous delivery of two bioactive drugs.

A. Aubertin, S. Peyrottes, C. Périgaud, 2021, European journal of medicinal chemistry.

Author names and aﬀiliations

A. Aubertin, S. Peyrottes, Christian, 2021 .

Synthesis of Certain Heterodimers Expected as HIV-1 Reverse Transcriptase Inhibitors

A. Aubertin, C. Fossey, D. Ladurée, 2003, Nucleosides, nucleotides & nucleic acids.

SYNTHESIS OF 5-ALKENYLATED D4T ANALOGUES VIA THE Pd-CATALYZED CROSS-COUPLING REACTION

A. Aubertin, A. Kirn, S. Benzaria, 2001, Nucleosides, nucleotides & nucleic acids.

Synthesis and Antiviral Activity of C-5 Substituted β-D- and β-L-D4T Analogues

A. Aubertin, A. Kirn, S. Benzaria, 2000 .

Synthesis and Antiviral Activity of C-5 Substituted Analogues of D4T Bearing Methylamino- or Methyldiamino-Linker Arms

A. Aubertin, A. Kirn, S. Benzaria, 2000, Nucleosides, nucleotides & nucleic acids.

Synthesis and evaluation of "AZT-HEPT", "AZT-pyridinone", and "ddC-HEPT" conjugates as inhibitors of HIV reverse transcriptase.

C. Nguyen, C. Monneret, D. Grierson, 2000, Journal of medicinal chemistry.

Synthesis and antiviral activity of C-5 substituted beta-D- and beta-L-D4T analogues.

A. Aubertin, A. Kirn, S. Benzaria, 2000, Nucleosides, nucleotides & nucleic acids.

Synthesis of novel C-5 substituted d4T analogues bearing linker arms as potential anti-HIV agents.

A. Aubertin, A. Kirn, F. Camara, 1999, Nucleosides & nucleotides.

Synthesis and anti-HIV activity of novel N-1 side chain-modified analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).

C. Monneret, R. Benhida, D. Grierson, 1997, Journal of medicinal chemistry.

Synthesis, Decomposition Pathways and “In Vitro” Evaluation of Bioreversible Phosphotriesters of Azt

J. Imbach, A. Pompon, A. Aubertin, 1995 .

Increase of the adenallene anti-HIV activity in cell culture using its bis(tBuSATE) phosphotriester derivative.

H. Mitsuya, J. Imbach, A. Aubertin, 2002, Bioorganic & medicinal chemistry letters.

Synthesis, in vitro antiviral evaluation, and stability studies of bis(S-acyl-2-thioethyl) ester derivatives of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) as potential PMEA prodrugs with improved oral bioavailability.

H. Pelicano, J. Imbach, A. Aubertin, 1996, Journal of medicinal chemistry.

Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.

H. Pelicano, J. Imbach, A. Aubertin, 1994, Biochemical pharmacology.

S-acyl-2-thioethyl phosphoramidate diester derivatives as mononucleotide prodrugs.

J. Imbach, A. Aubertin, C. Périgaud, 2003, Journal of medicinal chemistry.

A short route to new cyclobutene nucleoside analogues

F. Huet, A. Aubertin, C. Alexandre, 2002 .

Comparison of Cytotoxicity of Mononucleoside Phosphotriester Derivatives Bearing Biolabile Phosphate Protecting Groups in Normal Human Bone Marrow Progenitor Cells

J. Imbach, J. Sommadossi, A. Aubertin, 1996 .

SYNTHESIS AND STUDY OF A NEW SERIES OF PHOSPHORAMIDATE DERIVATIVES AS MONONUCLEOTIDE PRODRUGS

J. Imbach, A. Aubertin, C. Périgaud, 2001, Nucleosides, nucleotides & nucleic acids.

S-Acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs.

J. Imbach, A. Aubertin, S. Peyrottes, 2000, Journal of medicinal chemistry.

Rational design of a new series of mixed anti-HIV pronucleotides.

J. Imbach, A. Pompon, A. Aubertin, 1998, Bioorganic & medicinal chemistry letters.

Synthesis and Antiviral Evaluation of SATE-Foscarnet Prodrugs and New Foscarnet—AZT Conjugates

J. Imbach, J. Sommadossi, A. Aubertin, 1998, Antiviral chemistry & chemotherapy.

Nucleoside homodimerisation by cross metathesis

R. Granet, P. Krausz, A. Aubertin, 2001 .

Polyclonal Immunoglobulin G from Patients Neutralizes Human Immunodeficiency Virus Type 1 Primary Isolates by Binding Free Virions, but without Interfering with an Initial CD4-Independent Attachment of the Virus to Primary Blood Mononuclear Cells

A. Aubertin, C. Moog, R. Burrer, 2003, Journal of Virology.

Preparation and Properties of an Inhibitory Extract from Frog Virus 3 Particles

A. Aubertin, A. Kirn, H. Nonnenmacher, 1973, Journal of virology.

Preparation andProperties ofan Inhibitory Extract fromFrogVirus 3Particles

A. Aubertin, A. Kirn, H. Nonnenmacher, 1973 .

Tosylation/mesylation of 4-hydroxy-3-nitro-2-pyridinones as an activation step in the construction of dihydropyrido[3,4-b] benzo[f][1,4]thiazepin-1-one based anti-HIV agents

D. Grierson, A. Aubertin, P. Storck, 2005 .

Synthesis of Polyhydroxylated Pyrano‐Pyrrole Derivatives from Carbohydrate Precursors

F. Huet, A. Aubertin, D. Dubreuil, 2007 .

Deoxyribonucleoside 2'- or 3'-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription.

J. Balzarini, J. Décout, A. Aubertin, 2003, Journal of medicinal chemistry.

Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase, RNase H, and Integrase Activities by Hydroxytropolones

C. Isel, J. Mouscadet, R. Marquet, 2005, Antimicrobial Agents and Chemotherapy.

Cyclic PNA-based compound directed against HIV-1 TAR RNA: modelling, liquid-phase synthesis and TAR binding.

C. Bailly, C. Di Giorgio, R. Terreux, 2004, Organic & biomolecular chemistry.

Synthesis and Antiviral Evaluation of D4T Analogues with a Spacer Arm Between Glucidic and Base Moieties.

P. Krausz, A. Aubertin, Vincent Roy, 2005 .

Synthesis and Antiviral Evaluation of Azt Analogues with A Spacer Arm Between Glucidic and Base Moieties. Part II

P. Krausz, A. Aubertin, Vincent Roy, 2007, Nucleosides, nucleotides & nucleic acids.

Synthesis and Anti‐HIV Activity of Novel N‐1 Side Chain‐Modified Analogues of 1‐((2‐Hydroxyethoxy)methyl)‐6‐(phenylthio)thymine (HEPT).

C. Monneret, R. Benhida, D. Grierson, 1997 .

Synthesis of new acyclonucleosides comprising unexpected regioisomers in the case of purines

F. Huet, A. Aubertin, N. Bourgougnon, 2003 .

Stereospecific synthesis and biological evaluations of beta-L-pentofuranonucleoside derivatives of 5-fluorouracil and 5-fluorocytosine.

E. De Clercq, J. Balzarini, J. Sommadossi, 2001, European journal of medicinal chemistry.

Synthesis of new carbocyclic oxetanocin analogues

A. Aubertin, E. Bisagni, M. Legraverend, 1995 .

Stereoisomeric Imidazolo‐Pentoses − Synthesis, Chiroptical Properties, and Evaluation as Glycosidase Inhibitors

A. Aubertin, F. Gessier, H. Steiner, 2001 .

Synthesis of some cyclic and acyclic nucleoside analogues derived from 4-(trifluoromethyl)pyrimidines

A. Aubertin, C. Mirand, H. Berber, 2001 .

New Unnatural L-Nucleoside Enantiomers:From Their Stereospecific Synthesis to Their Biological Activities

R. Schinazi, J. Imbach, J. Sommadossi, 1997 .

2′-and/or 3Y-Deoxy-β-L-pentofuranosyl Nucleoside Derivatives: Stereospecific Synthesis and Antiviral Activities

R. Schinazi, J. Imbach, J. Sommadossi, 1995 .

Synthesis and Antiviral Evaluation of 3′-Deoxy-β-L-erythro-pentofuranosyl Nucleosides of the Five Naturally Occurring Nucleic Acid Bases

J. Imbach, A. Aubertin, A. Kirn, 1995 .

Systematic Synthesis and Antiviral Evaluation of α-L-Arabinofuranosyl and 2′-Deoxy-α-L-Erythro-Pento-Furanosyl Nucleosides of the Five Naturally Occurring Nucleic Acid Bases

J. Imbach, A. Aubertin, A. Kirn, 1991 .

3′-Substituted Thymine α-L-nucleoside Derivatives as Potential Antiviral Agents: Synthesis and Biological Evaluation

J. Imbach, A. Aubertin, A. Kirn, 1991 .

Synthesis of mono- and polyhydroxylated cyclobutane nucleoside analogs

F. Huet, Arnaud Nourry, R. Benhida, 2005 .

An efficient synthesis of dienic nucleoside analogues via a Mitsunobu reaction

F. Huet, A. Aubertin, C. Alexandre, 2003 .

Potential antiviral agents. Part II. Synthesis and antiviral evaluation of pyrazinones substituted with acyclic chains.

R. Granet, P. Krausz, A. Aubertin, 1998, Nucleosides & nucleotides.

Total synthesis of a Pepstatin analogue incorporating two trifluoromethyl hydroxymethylene isosteres

M. Zanda, W. Panzeri, A. Arnone, 2000 .

Synthesis and anti-HIV evaluation of water-soluble calixarene-based bithiazolyl podands.

A. Aubertin, J. Regnouf-de-Vains, G. Laumond, 2010, Bioorganic & Medicinal Chemistry.

S-acyl-2-thioethyl aryl phosphotriester derivatives of AZT: synthesis, antiviral activity, and stability study.

J. Imbach, A. Aubertin, G. Coussot, 2003, Journal of medicinal chemistry.

Increase of the Anti‐HIV Activity of D4T in Human T‐Cell Culture by the Use of the Sate Pronucleotide Approach

J. Imbach, A. Aubertin, A. Kirn, 1996 .

Synthesis, anti-HIV activity, and stability studies of 5'-phosphorofluoridate derivatives of AZT.

J. Imbach, A. Aubertin, A. Krayevsky, 2001, Bioorganic chemistry.

New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.

P. Vierling, J. Greiner, A. Aubertin, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro biological evaluation of valine-containing prodrugs derived from clinically used HIV-protease inhibitors.

P. Vierling, J. Greiner, A. Aubertin, 2008, European journal of medicinal chemistry.

Solubilised viral proteins produce fatal hepatitis in mice

A. Aubertin, A. Kirn, A. Bingen, 1977, Nature.

Specific and non-specific immunity and protection of macaques against SIV infection.

P. Roques, D. Dormont, A. Aubertin, 1992, Vaccine.

Synthesis and anti-HIV activity of some novel arylphosphate and H-phosphonate derivatives of 3'-azido-2',3'-dideoxythymidine and 2',3'-didehydro-2',3'-dideoxythymidine.

A. Aubertin, R. Guedj, A. Ayi, 1999, Antiviral research.

Synthesis of single- and double-chain fluorocarbon and hydrocarbon galactosyl amphiphiles and their anti-HIV-1 activity.

A M Aubertin, J. Fantini, P. Vierling, 2000, Carbohydrate research.

Enantiomeric 2',3'-dideoxycytidine derivatives are potent human immunodeficiency virus inhibitors in cell cultures.

R. Schinazi, J. Imbach, J. Sommadossi, 1994, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

Enantioselectivity of ribonucleotide reductase: a first study using stereoisomers of pyrimidine 2'-azido-2'-deoxynucleosides.

A. Aubertin, C. Périgaud, F. Focher, 2004, Biochemical pharmacology.

Synthesis and antiviral activity of aryl phosphoramidate derivatives of β-D- and β-L-C-5-Substituted 2’,3’-didehydro-2’,3’-dideoxy-uridine bearing linker arms

A. Aubertin, C. Fossey, D. Ladurée, 2005, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of new nucleoside analogues comprising a methylenecyclobutane unit

F. Huet, A. Aubertin, N. Bourgougnon, 2005 .

8-Modified-2′-Deoxyadenosine Analogues Induce Delayed Polymerization Arrest during HIV-1 Reverse Transcription

Roland Marquet, Johnson Mak, C. Isel, 2011, PloS one.

Synthesis and Primary Evaluation of Novel HIV-1 Inhibitors

V. Vivet-Boudou, R. Marquet, A. Aubertin, 2007, Nucleosides, nucleotides & nucleic acids.

Stereospecific Synthesis and Biological Evaluations of β‐L‐Pentofuranonucleoside Derivatives of 5‐Fluorouracil and 5‐Fluorocytosine.

J. Balzarini, E. Clercq, J. Sommadossi, 2001 .

New bis(SATE) prodrug of AZT 5'-monophosphate: in vitro anti-HIV activity, stability, and potential oral absorption.

P. Augustijns, J. Imbach, A. Pompon, 2001, Journal of pharmaceutical sciences.

Permissivity of primary cultures of human Kupffer cells for HIV-1.

D. Jaeck, A. Steffan, A. Aubertin, 1990, AIDS research and human retroviruses.

Synthesis and antiviral evaluation of pyrazinones substituted with acyclic chains.

R. Granet, P. Krausz, A. Aubertin, 1998, Nucleosides & nucleotides.

Intracellular delivery of nucleoside monophosphates through a reductase-mediated activation process.

J. Imbach, A. Pompon, A. Aubertin, 1993, Antiviral research.

Synthesis and Anti-HIV Activity of Some Heterodimers [NRTI]-Glycyl-Succinyl-[Trovirdine Analogue] of Known HIV-1 Reverse Transcriptase Inhibitors

A. Aubertin, C. Fossey, D. Ladurée, 2003, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and anti-HIV evaluation of hybrid-type prodrugs conjugating HIV integrase inhibitors with d4t by self-cleavable spacers containing an amino acid residue

Anh Vu, A. Aubertin, I. Zarafu, 2007, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and Primary Evaluation of Novel HIV‐1 Inhibitors

V. Vivet-Boudou, R. Marquet, A. Aubertin, 2008 .

Mononucleoside phosphorodithiolates as mononucleotide prodrugs.

A. Aubertin, S. Peyrottes, C. Périgaud, 2021, European journal of medicinal chemistry.

Thymidine kinase induction in frog virus 3 infected mouse cells.

A. Aubertin, M. Lonchampt, 1974, Virology.

The Pronucleotide Approach. I. Synthesis, Anti-HIV Activity and Preliminary Stability Studies of Mononucleoside S,S′-Bis(O-acyl-2-oxyethyl) Phosphorodithiolates

J. Imbach, A. Pompon, A. Aubertin, 1997 .

Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors.

C. Nguyen, M. Andreola, V. Dollé, 2000, Journal of medicinal chemistry.

New Acyclonucleosides: Synthesis and Anti-HIV Activity

P. Krausz, A. Aubertin, R. Zerrouki, 2005, Nucleosides, nucleotides & nucleic acids.

Bis-14-membered ring diketal diamines: synthesis and evaluation of their anti-HIV and anti-tumoral activities.

A. Aubertin, F. Pélissier, D. Dugat, 2009, European journal of medicinal chemistry.

Synthesis, anti-HIV activity and stability studies of 3'-azido-2',3'-dideoxythymidine 5'-fluorophosphate.

J. Imbach, A. Aubertin, A. Krayevsky, 1999, Nucleosides & nucleotides.

Increase of the anti-HIV activity of D4T in human T-cell culture by the use of the sate pronucleotide approach

J. Imbach, A. Aubertin, A. Kirn, 1995 .

Synthesis and Anti-HIV Activity of Prodrugs Derived from Saquinavir and Indinavir

P. Vierling, J. Greiner, A. Aubertin, 2000, Antiviral chemistry & chemotherapy.

5'-Hydrogenphosphonates of anti-HIV nucleoside analogues revisited: controversial mode of action.

J. Imbach, A. Pompon, A. Aubertin, 1993, Antiviral research.

Permissiveness of kupffer cells for simian immunodeficiency virus (SIV) and morphological changes in the liver of rhesus monkeys at different periods of SIV infection

A. Steffan, A. Aubertin, A. Kirn, 1995, Hepatology.

Signs of Kupffer cell involvement in productive simian immunodeficiency virus infection in monkey liver.

A. Steffan, A. Aubertin, A. Kirn, 1994, Research in virology.

Morphine stimulates HIV replication in primary cultures of human Kupffer cells.

D. Jaeck, A. Aubertin, A. Kirn, 1991, Research in virology.

Synthesis and Anti-HIV Evaluation of 7-Deaza Analogues of Carbovir

A. Aubertin, E. Bisagni, M. Legraverend, 1994 .

DESIGN OF NEW MONONUCLEOTIDE PRODRUGS: ARYL (SATE) PHOSPHOTRIESTER DERIVATIVES

J. Imbach, A. Pompon, A. Aubertin, 2001, Nucleosides, nucleotides & nucleic acids.

Efavirenz in plasma from HIV-infected patients does not directly block reverse transcriptase activity in cell-free assays but inhibits HIV replication in cellular assays.

G. Pancino, A. Aubertin, S. Richert, 2006, AIDS research and human retroviruses.

Inhibitors Interacting with the Magnesium Binding Site of Reverse Transcriptase: Synthesis and Biological Activity Studies of 3′-(Ω-Amino-Acyl) Amino-3′-Deoxy-Thymidine

J. Biellmann, A. Aubertin, T. V. Goud, 2008, Nucleosides, nucleotides & nucleic acids.

A convenient synthesis of 1-ethoxymethyl-5-nitro-6-substituted uracils

C. Monneret, R. Benhida, D. Grierson, 1996 .

In vivo inactivation of Nef ITAM motif of chimeric simian/human immunodeficiency virus SHIVsbg-YE correlates with absence of increased virulence in Chinese rhesus macaques.

A. Aubertin, B. Lafont, C. Beyer, 2003, Virology.

Persistence of Pathogenic Challenge Virus in Macaques Protected by Simian Immunodeficiency Virus SIVmacΔnef

M. Kieny, V. Monceaux, A. Aubertin, 2001, Journal of Virology.

Effect of an elevated temperature on the replication of HIV1 in a monocytic cell line.

A. Aubertin, A. Kirn, C. Schweitzer-Thumann, 1994, Research in virology.

CD4+ CCR5+ T-Cell Dynamics during Simian Immunodeficiency Virus Infection of Chinese Rhesus Macaques

G. Silvestri, J. Estaquier, V. Monceaux, 2007, Journal of Virology.

Antibody-Mediated Neutralization of Primary Human Immunodeficiency Virus Type 1 Isolates: Investigation of the Mechanism of Inhibition

C. Spenlehauer, A. Aubertin, A. Kirn, 2001, Journal of Virology.

DNA damage: a consequence of the combined effect of virus infection and incorporated radioactive thymidine.

A. Aubertin, A. Kirn, E. Fellinger, 1979, Biochemical and biophysical research communications.

Neutralizing as well as non-neutralizing polyclonal immunoglobulin (Ig)G from infected patients capture HIV-1 via antibodies directed against the principal immunodominant domain of gp41.

A. Aubertin, C. Moog, R. Burrer, 2005, Virology.

Early changes in peripheral blood T cells during primary infection of rhesus macaques with a pathogenic SIV

J. Estaquier, J. Ameisen, V. Monceaux, 2000, Journal of medical primatology.

Immunoglobulin G (IgG) and IgA, but also Nonantibody Factors, Account for In Vitro Neutralization of Human Immunodeficiency Virus (HIV) Type 1 Primary Isolates by Serum and Plasma of HIV-Infected Patients

F. Barré-Sinoussi, G. Pancino, A. Aubertin, 2001, Journal of Virology.

Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals

H. Fleury, A. Aubertin, A. Kirn, 1997, Journal of virology.

The major population of PHA-stimulated PBMC infected by R5 or X4 HIV variants after a single cycle of infection is predominantly composed of CD45RO+CD4+ T lymphocytes

A. Aubertin, C. Moog, V. Holl, 2006, Archives of Virology.

Amphiphilic anionic analogues of galactosylceramide: synthesis, anti-HIV-1 activity, and gp120 binding.

J. Fantini, P. Vierling, J. Greiner, 2001, Journal of medicinal chemistry.

Mhc haplotype M3 is associated with early control of SHIVsbg infection in Mauritian cynomolgus macaques.

N. Rose, R. Stebbings, A. Aubertin, 2010, Tissue antigens.

B-cell continuous epitopes of the SIVmac-251 envelope protein in experimentally infected macaques.

R. Benarous, D. Dormont, H. Durand, 1995, Research in virology.

Localization of viral protein X in simian immunodeficiency virus macaque strain and analysis of its packaging requirements.

D. Spehner, M. Mehtali, A. Aubertin, 1994, The Journal of general virology.

Positive role of macaque cytotoxic T lymphocytes during SIV infection: decrease of cellular viremia and increase of asymptomatic clinical period.

J. Levy, J. Guillet, H. Gras-masse, 1997, FEMS immunology and medical microbiology.

Prodrugs of HIV protease inhibitors-saquinavir, indinavir and nelfinavir-derived from diglycerides or amino acids: synthesis, stability and anti-HIV activity.

P. Vierling, J. Greiner, A. Aubertin, 2004, Organic & biomolecular chemistry.

Rational design of a new series of pronucleotide.

J. Imbach, A. Pompon, A. Aubertin, 2001, Bioorganic & medicinal chemistry letters.

Susceptibility of recombinant porcine endogenous retrovirus reverse transcriptase to nucleoside and non-nucleoside inhibitors

F. X. Wilhelm, J. Fishman, A. Aubertin, 2002, Cellular and Molecular Life Sciences CMLS.

Disease progression in macaques with low SIV replication levels: on the relevance of TREC counts

J. Estaquier, J. Ameisen, V. Monceaux, 2005, AIDS.

Nonneutralizing Antibodies Are Able To Inhibit Human Immunodeficiency Virus Type 1 Replication in Macrophages and Immature Dendritic Cells

S. Zolla-Pazner, A. Aubertin, C. Moog, 2006, Journal of Virology.

Involvement of Fc gamma RI (CD64) in the mechanism of HIV-1 inhibition by polyclonal IgG purified from infected patients in cultured monocyte-derived macrophages.

A. Bohbot, A. Aubertin, C. Moog, 2004, Journal of immunology.

AZT and AZT-monophosphate Prodrugs Incorporating HIV-protease Substrate Fragment: Synthesis and Evaluation as Specific Drug Delivery Systems

A. Di Giorgio, M. Mehiri, A. Aubertin, 2006, Antiviral chemistry & chemotherapy.

Synthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3'-azido-2',3'-dideoxythymidine.

J. Imbach, A. Aubertin, C. Périgaud, 1999, Nucleosides & nucleotides.

Expression of frog virus 3 early genes after ultraviolet irradiation.

J. Martín, A. Aubertin, A. Kirn, 1982, Virology.

Involvement of FcγR I (CD64) in the Mechanism of HIV-1 Inhibition by Polyclonal IgG Purified from Infected Patients in Cultured Monocyte-Derived Macrophages1

A. Bohbot, A. Aubertin, C. Moog, 2004, The Journal of Immunology.

Multiplication of human immunodeficiency virus in primary cultures of human Kupffer cells--possible role of liver macrophage infection in the physiopathology of AIDS.

D. Jaeck, A. Steffan, A. Aubertin, 1990, Research in virology.

Neutralization of primary human immunodeficiency virus type 1 isolates: a study of parameters implicated in neutralization in vitro.

H. Fleury, C. Spenlehauer, F. Letourneur, 1997, AIDS research and human retroviruses.

Morphological changes in lymph nodes and expression of VCAM1 and cytokines at the late stages of SIV-induced disease in rhesus monkeys.

A. Steffan, A. Aubertin, A. Kirn, 1995, Research in virology.

Extensive apoptosis in lymphoid organs during primary SIV infection predicts rapid progression towards AIDS

J. Estaquier, J. Ameisen, Y. Rivière, 2003, AIDS.

Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell

Philippe Dumas, Roland Marquet, Patrick Pale, 2006, Nucleic acids research.

Study of the V3 Loop as a Target Epitope for Antibodies Involved in the Neutralization of Primary Isolates versus T-Cell-Line-Adapted Strains of Human Immunodeficiency Virus Type 1

H. Fleury, C. Spenlehauer, A. Aubertin, 1998, Journal of Virology.

Synthesis and Anti-HIV Activity of Some [Nucleoside Reverse Transcriptase Inhibitor]-C5′-Linker-[Integrase Inhibitor] Heterodimers as Inhibitors of HIV Replication

A. Aubertin, C. Fossey, D. Ladurée, 2004, Journal of enzyme inhibition and medicinal chemistry.

A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor.

C. Bailly, S. Opi, A. Aubertin, 2004, Bioorganic & medicinal chemistry letters.

[Immunomodulating effect of HCV during the development of chronic hepatitis C: toward new therapeutic approaches].

A. Aubertin, M. Navas, F. Stoll-Keller, 2003, Bulletin de l'Academie nationale de medecine.

Immune responses following simian/human immunodeficiency virus (SHIV) challenge of rhesus macaques after human immunodeficiency virus (HIV)‐1 third variable domain (V3) loop‐based genetic immunization

D. Dormont, B. Boson, Y. Rivière, 2000, Journal of medical primatology.

High viral load and CD4 lymphopenia in rhesus and cynomolgus macaques infected by a chimeric primate lentivirus constructed using the env, rev, tat, and vpu genes from HIV-1 Lai.

M. Kieny, A. Aubertin, A. Kirn, 1996, Virology.

Cultured Monocyte-Derived Macrophages IgG Purified from Infected Patients in PolyclonalMechanism of HIV-1 Inhibition by R I ( CD 64 ) in the γ Involvement of Fc

A. Bohbot, A. Aubertin, C. Moog, 2004 .

One-round determination of seven leukocyte subsets in rhesus macaque blood by flow cytometry.

A. Aubertin, J. D'hautcourt, B. Lafont, 2000, Cytometry.

Synthesis of analogues of the benzodiazepine Ro 5-3335, antagonist of Tat HIV-1. Biological evaluation by Luciferase transactivation and anti-viral assay

M. Sinet, A. Aubertin, A. Kirn, 1996 .

A SHORT ROUTE TO ANALOGS OF GALACTOSPHINGOLIPIDS POSSESSING ANTI-HIV AND ANTI-ASPERGILLUS ACTIVITY

E. Perez, I. Rico-Lattes, A. Lattes, 1995 .

Infection of macaques after vaginal exposure to a primary isolate of SIVmac251.

L. Gauthier, P. Roques, A. Aubertin, 1995, AIDS.

The nucleotide sequence of a delayed early gene (31K) of frog virus 3

M P Schmitt, L Tondre, A Kirn, 1990, Nucleic Acids Res..

Approaches to the development of broadly protective HIV vaccines: challenges posed by the genetic, biological and antigenic variability of HIV-1: Report* from a meeting of the WHO-UNAIDS Vaccine Advisory Committee** Geneva, 21–23 February 2000

Guido Ferrari, N. Nathanson, Donald S. Burke, 2001, AIDS.

Generation of CD8+ T cell-generated suppressor factor and beta-chemokines by targeted iliac lymph node immunization in rhesus monkeys challenged with SHIV-89.6P by the rectal route.

T. Lehner, F. Barré-Sinoussi, M. Girard, 2000, AIDS research and human retroviruses.

Identifying patients with cerebral infarction within the time window compatible with reperfusion therapy, diagnostic performance of glutathione S-transferase-π (GST-π) and peroxiredoxin 1 (PRDX1): exploratory prospective multicentre study FLAG-1 protocol

Jean-Charles Sanchez, N. Girerd, K. Duarte, 2021, BMJ Open.

Effect of gamma-rays on infectivity and capacity for nuclear-associated and cytoplasmic DNA replication of FV 3 in chick embryo fibroblasts.

A. Aubertin, A. Kirn, C. Decker, 1970, Radiation research.