T. Parkinson

发表

Selective Inhibitors of Protozoan Protein N-myristoyltransferases as Starting Points for Tropical Disease Medicinal Chemistry Programs

Edward W. Tate, A. Holder, A. Wilkinson, 2012, PLoS neglected tropical diseases.

HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.

C. Cameron, F. Chisari, P. Gallay, 2010, Journal of hepatology.

Trypanosoma brucei Glycogen Synthase Kinase-3, A Target for Anti-Trypanosomal Drug Development: A Public-Private Partnership to Identify Novel Leads

Tod P. Holler, L. Maes, Richard O. Oduor, 2011, PLoS neglected tropical diseases.

Identification of HCV Inhibitors from a Cell-Based Sub-Genomic Replicon Screen

Stephen M. Shaw, D. Pryde, C. Pickford, 2013 .

An Integrated Transcriptomic and Meta-Analysis of Hepatoma Cells Reveals Factors That Influence Susceptibility to HCV Infection

F. Chisari, D. Robertson, V. Lohmann, 2011, PloS one.

Fluconazole therapy of oropharyngeal candidiasis in a patient with multiple endocrine failure does not correlate with Candida albicans susceptibility to fluconazole in vitro.

M. Martín, T. Parkinson, E. Field, 1996, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.

Cloning, sequencing, expression and allelic sequence diversity of ERG3 (C-5 sterol desaturase gene) in Candida albicans.

J. Bennett, B. Grimberg, Y. Miyazaki, 1999, Gene.

Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia

J. Wingard, J. Williams, R. Geller, 1997, Antimicrobial agents and chemotherapy.

from blood of two patients with leukemia . and amphotericin B-resistant Candida albicans Isolation and characterization of fluconazole

J. Wingard, R. Geller, C. Gilmore, 1996 .

The future of toll-like receptor therapeutics.

T. Parkinson, 2008, Current opinion in molecular therapeutics.

Staphylococcus aureus haem biosynthesis: characterisation of the enzymes involved in final steps of the pathway

L. M. Saraiva, S. Schroeder, M. Warren, 2015, Molecular microbiology.

Drug Discovery for Human African Trypanosomiasis

Rita Song, J. Siqueira-Neto, L. Freitas-Junior, 2015, Journal of biomolecular screening.

Fluconazole Resistance Associated with Drug Efflux and Increased Transcription of a Drug Transporter Gene, PDH1, inCandida glabrata

D. Ward, J. Bennett, Y. Miyazaki, 1998, Antimicrobial Agents and Chemotherapy.

Fluconazole resistance due to energy-dependent drug efflux in Candida glabrata

T. Parkinson, D. Falconer, C. Hitchcock, 1995, Antimicrobial agents and chemotherapy.

Candida dubliniensis: phylogeny and putative virulence factors.

G. Gilfillan, N. Gow, D. Coleman, 1998, Microbiology.

Mechanism of Fluconazole Resistance inCandida krusei

M. Ghannoum, S. Filler, A. Ibrahim, 1998, Antimicrobial Agents and Chemotherapy.

Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species: possible role for drug efflux in drug resistance

N. Gow, N. Gow, T. Parkinson, 1996, Antimicrobial agents and chemotherapy.

The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication*

P. Gallay, Feng Yang, Hengli Tang, 2009, The Journal of Biological Chemistry.

Small molecule drug discovery for Dengue and West Nile viruses: applying experience from hepatitis C virus.

D. Pryde, T. Parkinson, 2010, Future medicinal chemistry.

Targeting the non-structural proteins of hepatitis C virus: beyond hepatitis C virus protease and polymerase

D. Pryde, T. Parkinson, T. Holler, 2009, Expert opinion on drug discovery.

Novel Small-Molecule Inhibitors of RNA Polymerase III

L. Dick, T. Ocain, Vala Thoroddsen, 2003, Eukaryotic Cell.

The use of AlphaLISA technology to detect interaction between hepatitis C virus-encoded NS5A and cyclophilin A.

H. Waller, P. Gallay, T. Parkinson, 2010, Journal of virological methods.

Developed HTS SYBR Green Assay for Trypanosoma brucei Drug Discovery for Human African Trypanosomiasis: Identification of Novel Scaffolds by the Newly

Rita Song, J. Siqueira-Neto, L. Freitas-Junior, 2014 .

Candida glabrata , in PDH 1 Transporter Gene , Efflux and Increased Transcription of a Drug Fluconazole Resistance Associated with Drug

D. Ward, J. Bennett, Y. Miyazaki, 1998 .

Discovery of a highly potent series of TLR7 agonists.

G. Bish, D. Hay, James R. Hitchin, 2011, Bioorganic & medicinal chemistry letters.

Disruption of the gene encoding the ChiB1 chitinase of Aspergillus fumigatus and characterization of a recombinant gene product.

R. Barton, T. Parkinson, T. Fukamizo, 2003, Microbiology.

Repositioning: the fast track to new anti-malarial medicines?

R. Guy, Pavithra Viswanath, V. Avery, 2014, Malaria Journal.

An inhibitor of the epidermal growth factor receptor function does not affect the ability of human papillomavirus 11 to form warts in the xenografted immunodeficient mouse model.

L. Pustilnik, S. D. Patrick, P. Welsh, 2007, Antiviral research.

High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni

J. M. Gardner, Q. Bickle, A. Bell, 2016, PLoS neglected tropical diseases.

Investigating Toll-Like Receptor Agonists for Potential To Treat Hepatitis C Virus Infection

C. Laxton, T. Parkinson, N. Horscroft, 2007, Antimicrobial Agents and Chemotherapy.

Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction.

D. Hay, I. Gardner, C. Mowbray, 2009, Bioorganic & medicinal chemistry letters.

Repositioning: the fast track to new anti-malarial medicines?

Michele Connelly, R Kiplin Guy, Timothy Wells, 2014, Malaria Journal.

The impact of genomics on anti-infectives drug discovery and development.

T. Parkinson, 2002, Trends in microbiology.

Small molecule drug discovery for Dengue and West Nile viruses: applying experience from hepatitis C virus.

D. Pryde, T. Parkinson, 2010, Future medicinal chemistry.

Comparison of rat and human responses to toll-like receptor 7 activation.

Virgile Richard, C. Laxton, T. Parkinson, 2009, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Non-benzimidazole containing inhibitors of respiratory syncytial virus.

I. Gardner, D. Pryde, T. Parkinson, 2013, Bioorganic & medicinal chemistry letters.