J. H. Ryan

发表

Structural Basis for a New Mechanism of Inhibition of H I V-1 Integrase Identified by Fragment Screening and Structure-Based Design

J. Newman, T. Peat, J. Deadman, 2011, Antiviral chemistry & chemotherapy.

Tricyclic-isoxazolidine analogues via intramolecular 1,3-dipolar cycloaddition reactions of nitrones

M. Fuchter, A. Holmes, J. White, 2010 .

Native State Mass Spectrometry, Surface Plasmon Resonance, and X-ray Crystallography Correlate Strongly as a Fragment Screening Combination.

T. Peat, B. Ren, O. Dolezal, 2016, Journal of medicinal chemistry.

Synthesis of Bicyclic Enediynes from Bis[phenyl[(trifluoromethanesulfonyl)oxy]iodo]acetylene: A Tandem Diels-Alder/Palladium(II)- and Copper(I)-Cocatalyzed Cross-Coupling Approach.

P. Stang, J. H. Ryan, 1996, The Journal of organic chemistry.

Unexpected Isomerisation of a Fragment Analogue During Fragment-Based Screening of HIV Integrase Catalytic Core Domain

T. Peat, J. Deadman, G. P. Savage, 2015 .

Construction of the CSIRO Fragment Library

T. Peat, G. P. Savage, O. Dolezal, 2013 .

A gram-scale batch and flow total synthesis of perhydrohistrionicotoxin.

Simon Saubern, A. Holmes, J. H. Ryan, 2010, Chemistry.

The preparation of novel histrionicotoxin analogues and their activity towards the α4β2 and α7 nicotinic acetylcholine receptors

J. H. Ryan, M. Chebib, S. Saubern, 2017 .

Total synthesis of (-)-histrionicotoxin 285A and (-)-perhydrohistrionicotoxin.

A. Holmes, Helen T Horsley, J. H. Ryan, 2008, Organic letters.

1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides with Carbonyl Dipolarophiles Yielding Oxazolidine Derivatives

J. H. Ryan, A. G. Meyer, 2016, Molecules.

1,3-Dipolar cycloaddition reactions of phthalic anhydrides with an azomethine ylide

J. White, Hugo Santos, J. H. Ryan, 2015 .

Clean and efficient synthesis of O-silylcarbamates and ureas in supercritical carbon dioxide.

M. Fuchter, A. Holmes, J. H. Ryan, 2008, Chemical communications.

Chapter 6 - Seven-Membered Rings

J. Just, J. H. Ryan, Charlotte C Williams, 2013 .

Tricyclic-Isoxazolidine Analogues via Intramolecular 1,3-Dipolar Cycloaddition Reactions of Nitrones.

M. Fuchter, A. Holmes, J. White, 2010 .

Asymmetric Synthesis of a Hydroxylated Nine-membered Lactone from Tartaric Acid using the Claisen Rearrangement

A. Holmes, J. White, J. H. Ryan, 2010 .

Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes.

M. Fuchter, A. Holmes, Jin‐Kyun Lee, 2008, Chemical communications.

A novel in vitro image-based assay identifies new drug leads for giardiasis

K. Andrews, J. H. Ryan, T. Skinner-Adams, 2017, International journal for parasitology. Drugs and drug resistance.

The Diastereoselective Synthesis of Pyrroloindolines by Pd-Catalyzed Dearomative Cycloaddition of 1-Tosyl-2-vinylaziridine to 3-Nitroindoles

J. H. Ryan, M. Gardiner, C. Hyland, 2017 .

Seven-membered rings

Alex C. Bissember, J. Just, J. H. Ryan, 2021, Progress in Heterocyclic Chemistry.

Transition metal organometallic synthesis utilising diorganoiodine(III) reagents

A. Canty, J. H. Ryan, T. Rodemann, 2007 .

Knorr-Rabe partial reduction of pyrroles: Application to the synthesis of indolizidine alkaloids

J. H. Ryan, Jason A. Smith, Brendon S. Gourlay, 2008, Beilstein journal of organic chemistry.

Arylation of palladium(II) and platinum(II) by diphenyliodonium triflate to form metal(IV) species, and a structural analysis of an isomer of PtIMe2Ph(bpy) (bpy=2,2’-bipyridine)

A. Canty, B. Skelton, A. White, 2000 .

A new and high yielding synthesis of unstable pyrroles via a modified Clauson-Kaas reaction.

J. H. Ryan, Jason A. Smith, P. Molesworth, 2006 .

Benzoazepine-Fused Isoindolines via Intramolecular (3 + 2)-Cycloadditions of Azomethine Ylides with Dinitroarenes.

J. H. Ryan, M. Gardiner, A. G. Meyer, 2019, Organic letters.

1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides with Aromatic Dipolarophiles

J. H. Ryan, 2015 .

1,3-Dipolar cycloaddition-decarboxylation reactions of an azomethine ylide with isatoic anhydrides: formation of novel benzodiazepinones.

A. Holmes, J. White, J. H. Ryan, 2011, Organic letters.

Stereoselective reductions of N-Boc-hexahydro-1H-indolin-5(6H)-ones

P. Junk, A. Padwa, J. H. Ryan, 2007 .

Catalytic Formal [2 + 2 +1] Synthesis of Pyrroles from Alkynes and Diazenes via TiII/TiIV Redox Catalysis.

Ian A. Tonks, J. H. Ryan, W. Zachary, 2016 .

Notes- Addition of Silicon Hydrides to Olefinic Double Bonds. IV. The Addition to Styrene and α-Methylstyrene

J. H. Ryan, J. Speier, 1959 .

A suicide inhibitor of nematode trehalose-6-phosphate phosphatases

Jeong-Sun Kim, A. Hofmann, R. Gasser, 2019, Scientific Reports.

Pd-Catalyzed Dearomative [3 + 2] Cycloaddition of 3-Nitroindoles with 2-Vinylcyclopropane-1,1-dicarboxylates.

J. H. Ryan, M. Gardiner, C. Hyland, 2017, The Journal of organic chemistry.

The chromium trioxide–3,5-dimethylpyrazole complex: a mild and selective reagent for the oxidation of cyclopropyl hydrocarbons

J. H. Ryan, M. Banwell, M. Mackay, 1993 .

Reactivity of Diaryliodine(III) Triflates toward Palladium(II) and Platinum(II): Reactions of C(sp2)−I Bonds to Form Arylmetal(IV) Complexes; Access to Dialkyl(aryl)metal(IV), 1,4-Benzenediyl-Bridged Platinum(IV), and Triphenylplatinum(IV) Species; and Structural Studies of Platinum(IV) Complexes

Jim Patel, A. Canty, B. Skelton, 2004 .

Molecular Markers for Pyrethrin Autoxidation in Stored Pyrethrum Crop: Analysis and Structure Determination.

D. Winkler, J. H. Ryan, Oliver E Hutt, 2016, Journal of agricultural and food chemistry.

An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

J. H. Ryan, T. Skinner-Adams, J. Saunders, 2020, International journal for parasitology. Drugs and drug resistance.

A Subset Screen of the Compounds Australia Scaffold Library Identifies 7-Acylaminodibenzoxazepinones as Potent and Selective Hits for Anti-Giardia Drug Discovery

J. H. Ryan, T. Skinner-Adams, J. Zuegg, 2022, Biomedicines.

Competitive 1,3-Dipolar Cycloaddition Reactions of an Azomethine Ylide with Aromatic and Carbonyl Groups of Nitro-Substituted Isatoic Anhydrides

J. White, R. Mulder, J. H. Ryan, 2018 .

Small Molecule Inhibitors of the LEDGF Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design

Thomas S. Peat, Olan Dolezal, Janet Newman, 2012, PloS one.

Synthesis of 5-Aryloxazolidines via 1,3-Dipolar Cycloaddition Reaction of a Non-Stabilized Azomethine Ylide with Aromatic Aldehydes

A. Holmes, J. H. Ryan, L. S. Wong, 2007 .

Synthesis of 5‐Aryloxazolidines via 1,3‐Dipolar Cycloaddition Reaction of a Non‐Stabilized Azomethine Ylide with Aromatic Aldehydes.

A. Holmes, J. H. Ryan, L. S. Wong, 2008 .

Direct α-arylation of ketones: The reaction of cyclic ketone enolates with diphenyliodonium triflate

P. Stang, J. H. Ryan, 1997 .

Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

Oliver E. Hutt, E. Winzeler, S. Meister, 2019, Communications Biology.

Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone

Oliver E. Hutt, E. Winzeler, S. Meister, 2019, Communications Biology.

Discovery of 1,3,4-oxadiazoles with slow-action activity against Plasmodium falciparum malaria parasites

Oliver E. Hutt, A. Davey, K. Andrews, 2023, bioRxiv.

Synthetic approaches to [n](3,5)-troponophanes. Novel rearrangements of 10, 10-dichloro-1,2,6,7,8,9-hexahydro-4a,9a-methano-5H-benzocyyclohepten-2-one

R. Gable, J. H. Ryan, M. Banwell, 1994 .

Flow synthesis of tricyclic spiropiperidines as building blocks for the histrionicotoxin family of alkaloids

John Tsanaktsidis, Anastasios Polyzos, Andrew B. Holmes, 2010 .

A Scalable, Combined-Batch, and Continuous-Flow Synthesis of a Bio-Inspired UV-B Absorber

J. H. Ryan, K. E. Jarvis, M. York, 2019, Australian Journal of Chemistry.

Intramolecular nitrone dipolar cycloadditions: control of regioselectivity and synthesis of naturally-occurring spirocyclic alkaloids.

Joseph P. Adams, A. Bond, A. Holmes, 2012, Organic & biomolecular chemistry.

Clean and efficient synthesis of O-silylcarbamates and ureas in supercritical carbon dioxide.

M. Fuchter, A. Holmes, J. H. Ryan, 2008, Chemical Communications.

Preparation and Reactions of Siloxanylpropanals

J. H. Ryan, W. Dennis, 1970 .

Structural reassignment of a dibenz[

J. H. Ryan, T. Skinner-Adams, Snigdha Tiash, 2022, Australian Journal of Chemistry.