Mariela Bollini

发表

Synthesis, 2D-QSAR Studies and Biological Evaluation of Quinazoline Derivatives as Potent Anti-Trypanosoma cruzi Agents.

Mariela Bollini, A. M. Bruno, Martha E. Niño, 2019, Medicinal chemistry (Shariqah (United Arab Emirates)).

Trypanocidal Activity of Thioamide-Substituted Imidazoquinolinone: Electrochemical Properties and Biological Effects

A. Batlle, Mariela Bollini, A. M. Bruno, 2013, Evidence-based complementary and alternative medicine : eCAM.

Discovery of novel dengue virus entry inhibitors via a structure-based approach.

C. Cavasotto, A. Gamarnik, N. G. Iglesias, 2017, Bioorganic & medicinal chemistry letters.

A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase.

William L Jorgensen, W. L. Jorgensen, K. Anderson, 2014, Biochimica et biophysica acta.

Potent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance.

R. Siliciano, W. L. Jorgensen, K. Anderson, 2015, ACS medicinal chemistry letters.

Efficient discovery of potent anti-HIV agents targeting the Tyr181Cys variant of HIV reverse transcriptase.

William L. Jorgensen, Karen S. Anderson, Robert A. Domaoal, 2011, Journal of the American Chemical Society.

Extension into the entrance channel of HIV-1 reverse transcriptase--crystallography and enhanced solubility.

William L Jorgensen, Eddy Arnold, W. L. Jorgensen, 2013, Bioorganic & medicinal chemistry letters.

Challenges and approaches in the discovery of human immunodeficiency virus type‐1 non‐nucleoside reverse transcriptase inhibitors

Mariela Bollini, Leandro Battini, 2018, Medicinal research reviews.

Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase.

Robert A. Domaoal, W. L. Jorgensen, K. Anderson, 2012, Bioorganic & medicinal chemistry letters.

Structure‐based drug design for envelope protein E2 uncovers a new class of bovine viral diarrhea inhibitors that block virus entry

C. Cavasotto, D. Alvarez, Mariela Bollini, 2018, Antiviral research.

Hybrid Antimicrobial Films Containing a Polyoxometalate-Ionic Liquid

C. Streb, J. M. de la Fuente, M. J. Culzoni, 2022, ACS applied polymer materials.

Synthesis and Antichlamydial Activity of Molecules Based on Dysregulators of Cylindrical Proteases.

M. Conda-Sheridan, S. Ouellette, D. Murry, 2020, Journal of medicinal chemistry.

Discovery of Novel Bovine Viral Diarrhea Inhibitors Using Structure-Based Virtual Screening on the Envelope Protein E2

Natalia S. Adler, C. Cavasotto, D. Alvarez, 2018, Front. Chem..

Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents.

William L Jorgensen, Robert A. Domaoal, W. L. Jorgensen, 2011, Journal of medicinal chemistry.

Microwave-assisted rapid and efficient synthesis of C-alkyl imidazoisoquinolinone derivatives

Mariela Bollini, A. M. Bruno, Mariángeles González, 2009 .

Thalidomide analogues: Tumor necrosis factor-alpha inhibitors and their evaluation as anti-inflammatory agents.

Mariela Bollini, A. M. Bruno, J. J. Casal, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Microwave-assisted Friedländer synthesis of quinolines derivatives as potential antiparasitic agents

Gisela C. Muscia, S. Asís, Mariela Bollini, 2006 .

Picomolar inhibitors of HIV reverse transcriptase featuring bicyclic replacement of a cyanovinylphenyl group.

William L Jorgensen, W. L. Jorgensen, K. Anderson, 2013, Journal of the American Chemical Society.

Microwave‐Assisted Rapid and Efficient Synthesis of C‐Alkyl Imidazoisoquinolinone Derivatives.

Mariela Bollini, A. M. Bruno, M. Gonzales, 2009 .

Microwave-assisted Döbner Synthesis of 2-Phenylquinoline-4-carboxylic Acids and their Antiparasitic Activities

Gisela C. Muscia, S. Asís, Mariela Bollini, 2008 .

Microwave‐Assisted Friedlaender Synthesis of Quinolines Derivatives as Potential Antiparasitic Agents.

Gisela C. Muscia, S. Asís, Mariela Bollini, 2007 .

Design and Optimization of Quinazoline Derivatives: New Non-nucleoside Inhibitors of Bovine Viral Diarrhea Virus

Natalia S. Adler, Mariela Bollini, A. M. Bruno, 2020, Frontiers in Chemistry.

Chemical transformations of 3-amino-2-quinolones

Mariela Bollini, A. M. Bruno, C. Gaozza, 2003 .

Design, synthesis, and antitumor activity of new bis-aminomethylnaphthalenes.

Mariela Bollini, A. M. Bruno, J. J. Casal, 2008, Bioorganic & medicinal chemistry.

Synthesis of benzylidenecycloalkan-1-ones and 1,5-diketones under Claisen–Schmidt reaction: Influence of the temperature and electronic nature of arylaldehydes

Jorge D. Mufato, Mariela Bollini, J. Aguirre, 2017 .

New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.

D. Alvarez, Mariela Bollini, A. M. Bruno, 2009, Bioorganic & medicinal chemistry.

Convenient Route to Primary (Z)-Allyl Amines and Homologs

Mariela Bollini, H. Cerecetto, Mercedes González, 2008 .

Increased in vitro Anti‐HIV Activity of Caffeinium‐Functionalized Polyoxometalates

F. Kirchhoff, J. Münch, C. Streb, 2021, ChemMedChem.

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity

B. Schumacher, Gerry P. Crossan, Hernán Reingruber, 2022, Nature communications.

Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency.

Julian Tirado-Rives, William L Jorgensen, W. L. Jorgensen, 2013, Bioorganic & medicinal chemistry letters.

Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives.

William L. Jorgensen, Karen S. Anderson, Robert A. Domaoal, 2010, Bioorganic & medicinal chemistry letters.

Identification of potent bovine viral diarrhea virus inhibitors by a structure-based virtual screening approach.

Mariela Bollini, A. M. Bruno, J. J. Casal, 2019, Bioorganic & medicinal chemistry letters.

Endogenous formaldehyde scavenges cellular glutathione resulting in cytotoxic redox disruption

B. Schumacher, Ismene Karakasilioti, R. He, 2020, bioRxiv.

Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase

W. L. Jorgensen, J. Ippolito, A. Chan, 2022, Frontiers in Molecular Biosciences.

EVALUATION OF ANTIPARASITIC, ANTITUBERCULOSIS AND ANTIANGIOGENIC ACTIVITIES OF 3-AMINOQUINOLIN-2-ONE DERIVATIVES

Gisela C. Muscia, S. Asís, Mariela Bollini, 2006 .

A Machine Learning Model to Predict Drug Transfer Across the Human Placenta Barrier

C. Cavasotto, Mariela Bollini, Juan I. Di Filippo, 2021, Frontiers in Chemistry.

Combination of pose and rank consensus in docking-based virtual screening: the best of both worlds

Claudio N. Cavasotto, C. Cavasotto, Mariela Bollini, 2021, RSC advances.

Discovery of a Potent and Selective Chikungunya Virus Envelope Protein Inhibitor through Computer-Aided Drug Design.

Mariela Bollini, Leandro Battini, D. Fidalgo, 2021, ACS infectious diseases.

Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers.

W. L. Jorgensen, K. Anderson, Mariela Bollini, 2014, ACS medicinal chemistry letters.

Crystal structures of HIV-1 reverse transcriptase with picomolar inhibitors reveal key interactions for drug design.

William L Jorgensen, W. L. Jorgensen, K. Anderson, 2012, Journal of the American Chemical Society.

A novel optimized polyoxometalate-modified silver nanocomposite. Application to the development of antibacterial textiles

S. Collins, H. Goicoechea, M. J. Culzoni, 2023, Materials Today Communications.

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity

B. Schumacher, Gerry P. Crossan, Hernán Reingruber, 2022, Nature Communications.

Structure‐Based Evaluation of C5 Derivatives in the Catechol Diether Series Targeting HIV‐1 Reverse Transcriptase

W. L. Jorgensen, K. Anderson, Mariela Bollini, 2014, Chemical biology & drug design.

Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility.

William L Jorgensen, W. L. Jorgensen, K. Anderson, 2013, Bioorganic & medicinal chemistry letters.

De novo design approaches targeting an envelope protein pocket to identify small molecules against dengue virus.

Natalia S. Adler, C. Cavasotto, A. Gamarnik, 2019, European journal of medicinal chemistry.

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein

A. M. Riley, C. Camacho, D. Svergun, 2023, Science Signaling.

Antiviral drug discovery: Pyrimidine entry inhibitors for Zika and dengue viruses.

C. García, Mariela Bollini, D. Fidalgo, 2024, European journal of medicinal chemistry.