Zhonghuang Li

发表

Design Some New Type‐I c‐met Inhibitors Based on Molecular Docking and Topomer CoMFA Research

Shuguang Wu, Yuan-xin Tian, Yudong Shen, 2014, Molecular informatics.

Combined 3D-QSAR and Docking Modelling Study on Indolocarbazole Series Compounds as Tie-2 Inhibitors

Shuguang Wu, Yuan-xin Tian, Zhonghuang Li, 2011, International journal of molecular sciences.

Bisarylureas Based on 1H-Pyrazolo[3,4-d]pyrimidine Scaffold as Novel Pan-RAF Inhibitors with Potent Anti-Proliferative Activities: Structure-Based Design, Synthesis, Biological Evaluation and Molecular Modelling Studies

Guangfa Wang, Zhonghuang Li, Jiajie Zhang, 2017, Molecules.

Methyl-1-hydroxy-2-naphthoate, a novel naphthol derivative, inhibits lipopolysaccharide-induced inflammatory response in macrophages via suppression of NF-κB, JNK and p38 MAPK pathways

Wei Xu, Yuan-xin Tian, Zhonghuang Li, 2011, Inflammation Research.

Novel natural scaffold as hURAT1 inhibitor identified by 3D-shape-based, docking-based virtual screening approach and biological evaluation.

Shan Chang, Yuan-xin Tian, Yudong Shen, 2021, Bioorganic chemistry.

Insight into binding mechanisms of EGFR allosteric inhibitors using molecular dynamics simulations and free energy calculations

Zhonghuang Li, Shanhe Wan, Xiaoyun Wu, 2019, Journal of biomolecular structure & dynamics.

Geniposide inhibits high glucose-induced cell adhesion through the NF-κB signaling pathway in human umbilical vein endothelial cells

Wei Xu, Yuan-xin Tian, Zhonghuang Li, 2010, Acta Pharmacologica Sinica.

3D-QSAR study on 2,3-dihydroimidazo[4,5]-pyridin-2-one derivatives with a meta substitution pattern as V600EBRAF inhibitors

Shuguang Wu, Zhonghuang Li, Jiajie Zhang, 2013, Medicinal Chemistry Research.

The seafood Musculus senhousei shows anti-influenza A virus activity by targeting virion envelope lipids

Jian He, Shaohua Wu, Zhonghuang Li, 2020, Biochemical Pharmacology.

Praeruptorin D and E attenuate lipopolysaccharide/hydrochloric acid induced acute lung injury in mice.

Yuan-xin Tian, Zhonghuang Li, H. Jin, 2013, European journal of pharmacology.

Design and synthesis of proteolysis targeting chimeras (PROTACs) as an EGFR degrader based on CO-1686.

Shuyi Wang, Zhonghuang Li, Jiajie Zhang, 2022, European journal of medicinal chemistry.

Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.

Zhonghuang Li, Jiajie Zhang, Zichao Yang, 2022, Bioorganic & medicinal chemistry.

Molecular mechanism study of EGFR allosteric inhibitors using molecular dynamics simulations and free energy calculations

Zhonghuang Li, Jiajie Zhang, Shanhe Wan, 2021, Journal of biomolecular structure & dynamics.

Design, synthesis and biological evaluations of 2-amino-4-(1-piperidine) pyridine derivatives as novel anti crizotinib-resistant ALK/ROS1 dual inhibitors.

Yuan-xin Tian, Zhonghuang Li, Jiajie Zhang, 2019, European journal of medicinal chemistry.

Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor.

Guangfa Wang, Yuan-xin Tian, Zhonghuang Li, 2016, European journal of medicinal chemistry.

Design, synthesis, biological evaluation and molecular modeling of novel 1H-pyrazolo[3,4-d]pyrimidine derivatives as BRAFV600E and VEGFR-2 dual inhibitors.

Guangfa Wang, Zhonghuang Li, Jiajie Zhang, 2018, European journal of medicinal chemistry.

Toxic Markers of Matrine Determined Using 1H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo

Jian Shi, Zhonghuang Li, Jiajie Zhang, 2015, Evidence-based complementary and alternative medicine : eCAM.

Discovery and Computational Studies of Potent Covalent Kinase Inhibitors with α-Substituent Electrophiles Targeting Cysteine

Zhonghuang Li, Jiajie Zhang, Zichao Yang, 2023, J. Chem. Inf. Model..

Computational Studies of Potent Covalent Inhibitors on Wild Type or T790M/L858R Mutant Epidermal Growth Factor Receptor.

Zhonghuang Li, Jiajie Zhang, Zichao Yang, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Myrislignan Attenuates Lipopolysaccharide‐induced Inflammation Reaction in Murine Macrophage Cells Through Inhibition of NF‐κB Signalling Pathway Activation

Yuan-xin Tian, Zhonghuang Li, H. Jin, 2012, Phytotherapy research : PTR.

Mechanism of anti-hyperuricemia of isobavachin based on network pharmacology and molecular docking

Zhonghuang Li, Jian Luo, Jia-jie Zhang, 2023, Comput. Biol. Medicine.

Design, synthesis, biological evaluation and molecular modeling of novel 2-amino-4-(1-phenylethoxy) pyridine derivatives as potential ROS1 inhibitors.

Guangfa Wang, Yuan-xin Tian, Zhonghuang Li, 2018, European journal of medicinal chemistry.

Understand the acquired resistance of RTK inhibitors by computational receptor tyrosine kinases network

Tingting Zhang, Jiajie Zhang, Shaoyu Wu, 2018, Comput. Biol. Chem..

3D-QSAR study on 2,3-dihydroimidazo[4,5]-pyridin-2-one derivatives with a meta substitution pattern as V600EBRAF inhibitors

Shuguang Wu, Zhonghuang Li, Jiajie Zhang, 2014, Medicinal Chemistry Research.

Molecular dynamics simulation and free energy calculation studies of kinase inhibitors binding to active and inactive conformations of VEGFR-2.

Guangfa Wang, Yuan-xin Tian, Zhonghuang Li, 2015, Journal of molecular graphics & modelling.

Molecular Dynamics Study to Investigate the Dimeric Structure of the Full-Length α-Synuclein in Aqueous Solution

Shuwen Liu, Yuan-xin Tian, Zhonghuang Li, 2017, J. Chem. Inf. Model..

Design and Synthesis of Some Novel 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as Potential c-Met Inhibitors

Yuan-xin Tian, Lianbao Ye, Zhonghuang Li, 2012 .

Design, synthesis and molecular docking studies of some novel spiro[indoline-3, 4'-piperidine]-2-ones as potential c-Met inhibitors.

Shuguang Wu, Yuan-xin Tian, Lianbao Ye, 2012, European journal of medicinal chemistry.

A Novel and Highly Selective Epidermal Growth Factor Receptor Inhibitor, SMUZ106, for the Treatment of Glioblastoma

Zhonghuang Li, Jiajie Zhang, Zhengguang Zhu, 2023, Pharmaceutics.

The cytochrome P450 metabolic profiling of SMU-B in vitro, a novel small molecule tyrosine kinase inhibitor.

Zhonghuang Li, Jiajie Zhang, Zhengguang Zhu, 2020, Journal of pharmaceutical and biomedical analysis.