Alison Maloney

发表

Discovery of 4-azaindoles as novel inhibitors of c-Met kinase.

C. Meier, M. Batchelor, Mark Calmiano, 2009, Bioorganic & medicinal chemistry letters.

Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.

Paul Workman, Rainer Cramer, Chrisostomos Prodromou, 2002, Molecular cell.

The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors.

Paul Workman, Edward McDonald, Chrisostomos Prodromou, 2005, Bioorganic & medicinal chemistry letters.

Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin.

Paul Workman, Rainer Cramer, Marketa Zvelebil, 2007, Cancer research.

CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study

A. Lawson, Y. Hsu, L. Burkly, 2015, Arthritis Research & Therapy.

Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor

C. Daridon, T. Dörner, A. Wiedemann, 2016, Journal of Cell Communication and Signaling.

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX

P. Workman, P. Clarke, M. Valenti, 2013, Oncotarget.

WNT3A‐loaded exosomes enable cartilage repair

F. Dell’Accio, M. Perretti, C. Pitzalis, 2021, Journal of extracellular vesicles.

Assays for HSP90 and inhibitors.

L. Pearl, P. Workman, M. Walton, 2003, Methods in molecular medicine.

HSP90 as a new therapeutic target for cancer therapy: the story unfolds

P. Workman, Alison Maloney, 2002, Expert opinion on biological therapy.

Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase.

C. Meier, M. Batchelor, Mark Calmiano, 2009, Bioorganic & medicinal chemistry letters.

Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone

P. Workman, I. Judson, M. Walton, 2000, Oncogene.

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies.

S. Lakhani, P. Workman, I. Judson, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors.

L. Pearl, P. Workman, R. Marais, 2007, Cancer research.

Genes and proteins governing the cellular sensitivity to HSP90 inhibitors: a mechanistic perspective.

P. Workman, P. Clarke, Alison Maloney, 2003, Current cancer drug targets.

A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF

T. Ceska, A. Lawson, Anthony Scott-Tucker, 2021, Nature Communications.

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

Benjamin P. Cossins, T. Ceska, A. Lawson, 2019, Nature Communications.

Engagement of CD22 on B cells with the monoclonal antibody epratuzumab stimulates the phosphorylation of upstream inhibitory signals of the B cell receptor

C. Daridon, T. Dörner, A. Wiedemann, 2016, Journal of Cell Communication and Signaling.

Target occupancy biomarker assay development using a conformation-selective antibody against small-molecule-bound TNF.

M. Herrmann, Alison Maloney, T. Bourne, 2023, Bioanalysis.

TNFR1 membrane reorganization promotes distinct modes of TNFα signaling

P. Morton, S. Ameer-Beg, R. Marsh, 2019, Science Signaling.

Discovery of 4-azaindoles as novel inhibitors of c-Met kinase.

C. Meier, M. Batchelor, Mark Calmiano, 2009, Bioorganic & medicinal chemistry letters.