Wei-Min Chen

发表

Molecular modeling studies on imidazo[4,5-b]pyridine derivatives as Aurora A kinase inhibitors using 3D-QSAR and docking approaches.

P. Lan, Wan-Na Chen, Wei-Min Chen, 2011, European journal of medicinal chemistry.

3D-QSAR and molecular docking for the discovery of ketolide derivatives

Wei-Min Chen, Zhi-Xiong Ruan, De-Sheng Huangfu, 2013, Expert opinion on drug discovery.

Molecular modeling studies on phosphonic acid-containing thiazole derivatives: design for fructose-1,6-bisphosphatase inhibitors

Zhiqiang Wu, P. Lan, Wan-Na Chen, 2012, Journal of Molecular Modeling.

3D-QSAR and docking studies on 1-hydroxypyridin-2-one compounds as mutant isocitrate dehydrogenase 1 inhibitors

Yuanhao Zhai, Wei-Min Chen, Zhen-Ya Wang, 2016 .

Biological evaluation and chemoproteomics reveal potential antibacterial targets of a cajaninstilbene-acid analogue.

Wei-Min Chen, Jing Lin, Kuo Lu, 2020, European journal of medicinal chemistry.

3D-QSAR and molecular docking studies of azaindole derivatives as Aurora B kinase inhibitors

P. Lan, Wan-Na Chen, Wei-Min Chen, 2011, Journal of molecular modeling.

Synthesis and antibacterial activities of acylide derivatives bearing an aryl-tetrazolyl chain

Shufeng Zhou, Jiazhi Sun, Wei-Min Chen, 2014, Drug design, development and therapy.

Design, synthesis and evaluation of halogenated furanone derivatives as quorum sensing inhibitors in Pseudomonas aeruginosa.

H. Zhou, D. Hibbs, Wei-Min Chen, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Fibroblast Activation Protein α Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced Cardiotoxicity.

W. Ye, Min-feng Chen, Wei-Min Chen, 2017, Journal of medicinal chemistry.

Design, synthesis and antibacterial activity of novel ketolides bearing an aryltetrazolyl-substituted alkyl side chain

P. Lan, Wei-Min Chen, Ping-Hua Sun, 2011, The Journal of Antibiotics.

B4G2 Induces Mitochondrial Apoptosis by the ROS-Mediated Opening of Ca2+-Dependent Permeability Transition Pores

Zhe-Sheng Chen, W. Ye, P. Lan, 2015, Cellular Physiology and Biochemistry.

4-arylamidobenzyl substituted 5-bromomethylene-2(5H)-furanones for chronic bacterial infection.

F. Wang, Wei-Min Chen, Xing-Jun Xu, 2018, European journal of medicinal chemistry.

Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse resistance of HepG2/ADM and MCF-7/ADR cells

K. Fung, Zhe-Sheng Chen, L. Fu, 2013, Anti-cancer drugs.

BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitro and in vivo.

S. Ambudkar, J. Bhatnagar, Zhe-Sheng Chen, 2012, Molecular pharmaceutics.

Identification of the Residues in the Extracellular Domain of Thrombopoietin Receptor Involved in the Binding of Thrombopoietin and a Nuclear Distribution Protein (Human NUDC)*

Bo Yu, Wei-Min Chen, Qing Zhang, 2010, The Journal of Biological Chemistry.

Total Syntheses of the Amaryllidaceae Alkaloids Zephycandidine III and Lycosinine A and Their Evaluation as Inhibitors of Acetylcholinesterase

C. Jackson, P. Carr, A. Willis, 2017 .

Induction of differentiation of the acute myeloid leukemia cell line (HL-60) by a securinine dimer

Wei-Min Chen, Zhen-Ya Wang, Jing Lin, 2020, Cell death discovery.

Arenobufagin intercalates with DNA leading to G2 cell cycle arrest via ATM/ATR pathway

W. Ye, Wei-Min Chen, Dong-Mei Zhang, 2015, Oncotarget.

Novel virosecurinine bivalent mimetics as potent reversal agents against P-glycoprotein-mediated multidrug resistance.

Wei-Min Chen, Zhen-Ya Wang, Jing Lin, 2019, European journal of medicinal chemistry.

Novel cajaninstilbene acid derivatives as antibacterial agents.

W. Ye, Wei-Min Chen, Hong-Bin Zhang, 2015, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Cajaninstilbene Acid and Amorfrutins A and B as Inhibitors of the Pseudomonas aeruginosa Quorum Sensing System.

Wei-Min Chen, Xing-Jun Xu, Jing Lin, 2018, Journal of natural products.

Fluorescent Detection of the Ubiquitous Bacterial Messenger 3′,5′ Cyclic Diguanylic Acid by Using a Small Aromatic Molecule

Wei-Min Chen, Jing Lin, Jun Liu, 2020, Frontiers in Microbiology.

Theacrine, a purine alkaloid obtained from Camellia assamica var. kucha, attenuates restraint stress-provoked liver damage in mice.

R. He, Wei-Min Chen, H. Kurihara, 2013, Journal of agricultural and food chemistry.

Novel Oxazolidinone Antibacterial Analogues with a Substituted Ligustrazine C‐ring Unit

F. Wang, Wei-Min Chen, Zhi-Xiong Ruan, 2015, Chemical biology & drug design.

Novel 2, 8-bit derivatives of quinolines attenuate Pseudomonas aeruginosa virulence and biofilm formation.

Fang Wang, H. Zhou, Wei-Min Chen, 2019, Bioorganic & medicinal chemistry letters.

Design, Synthesis and Antibacterial Assay of Pinosylvin Acid Derivatives

Wei-Min Chen, Zhi-Zhong Geng, Ping-Hua Sun, 2016 .

A Bivalent Securinine Compound SN3-L6 Induces Neuronal Differentiation via Translational Upregulation of Neurogenic Transcription Factors

F. Liu, Xiaojie Huang, W. Ye, 2018, Front. Pharmacol..

Molecular mechanisms of bufadienolides and their novel strategies for cancer treatment.

Q. Qi, Sheng Wang, W. Ye, 2020, European journal of pharmacology.

Synthetic studies on erythromycin derivatives: reactivity of the C12-21 alkene.

Wei-Min Chen, 2006, Molecules.

Flueggedine, a novel axisymmetric indolizidine alkaloid dimer from Flueggea virosa

Guocai Wang, W. Ye, Xiao‐Jun Huang, 2013 .

Design and prediction of new anticoagulants as a selective Factor IXa inhibitor via three-dimensional quantitative structure-property relationships of amidinobenzothiophene derivatives

Shufeng Zhou, Wei-Min Chen, Jialiang Guo, 2015, Drug design, development and therapy.

Betulinic Acid and its Derivatives as Potential Antitumor Agents

Lei Wang, W. Ye, Wei-Min Chen, 2015, Medicinal research reviews.

3D-QSAR and docking studies on pyrazolo[4,3-h]qinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors.

Ping-Hua Sun, Wan-Na Chen, P. Lan, 2010, Bioorganic & medicinal chemistry letters.

Design, synthesis and anti-inflammatory evaluation of novel 5-benzylidene-3,4-dihalo-furan-2-one derivatives.

F. Wang, Wei-Min Chen, Ping-Hua Sun, 2014, European journal of medicinal chemistry.

3D-QSAR and Molecular Docking Studies on Fused Pyrazoles as p38α Mitogen-Activated Protein Kinase Inhibitors

P. Lan, Wei-Min Chen, Jun-Rong Sun, 2010, International journal of molecular sciences.

Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of 5‐Substituted 3,4‐Dihalo‐5H‐furan‐2‐one Derivatives on Pseudomonas aeruginosa

Wan-Na Chen, Wei-Min Chen, Ping-Hua Sun, 2012, Chemical biology & drug design.

Synthetic studies of erythromycin derivatives: 6-O-methylation of (9S)-12,21-anhydro-9-dihydroerythromycin A derivatives

Wei-Min Chen, H. Wong, Xiaodong Lin, 2003 .

Flueggines A and B, two new dimeric indolizidine alkaloids from Flueggea virosa.

Xiao‐Jun Huang, W. Ye, C. Che, 2011, Organic letters.

Synthesis and antibacterial activity of C-12 pyrazolinyl spiro ketolides.

P. Lan, Lei Hu, Wei-Min Chen, 2010, European journal of medicinal chemistry.

Facile Synthesis of the Neuraminidase Inhibitor Peramivir

Wei-Min Chen, Ping-Hua Sun, Jian-xin Chen, 2013 .

Unexpected ring contraction and oxidation rearrangement reactions of securinine

W. Ye, Xiao‐Jun Huang, Wei-Min Chen, 2012 .

Synthesis and antiproliferative evaluation of 23-hydroxybetulinic acid derivatives.

W. Ye, P. Lan, Wei-Min Chen, 2011, European journal of medicinal chemistry.

Design and Synthesis of Dimeric Securinine Analogues with Neuritogenic Activities.

Xiaojie Huang, N. Ip, Lei Shi, 2016, ACS chemical neuroscience.

Regioselective and stereoselective photodimerization of securinine-type and norsecurinine-type alkaloids

W. Ye, Xiao‐Jun Huang, Wei-Min Chen, 2014 .

Novel bivalent securinine mimetics as topoisomerase I inhibitors

Wei-Min Chen, Zhen-Ya Wang, M. Banwell, 2017, MedChemComm.

Chemical synthesis and biological activities of Securinega alkaloids

Wei-Min Chen, Wen Zhang, 2011 .

Strigolactones: a plant phytohormone as novel anti-inflammatory agents.

Wei-Min Chen, Jialiang Guo, Ping-Hua Sun, 2018, MedChemComm.

Alopecuroides A-E, Matrine-Type Alkaloid Dimers from the Aerial Parts of Sophora alopecuroides.

Yao-lan Li, Guocai Wang, W. Ye, 2019, Journal of natural products.

Novel 2-Substituted 3-Hydroxy-1,6-dimethylpyridin-4(1H)-ones as Dual-Acting Biofilm Inhibitors of Pseudomonas aeruginosa.

Wei-Min Chen, Jinsong Hou, Ping-Hua Sun, 2020, Journal of medicinal chemistry.

3D-QSAR studies on betulinic acid and betulin derivatives as anti-HIV-1 agents using CoMFA and CoMSIA

P. Lan, Wan-Na Chen, Wei-Min Chen, 2011, Medicinal Chemistry Research.

Anti-Inflammatory Effects of Cajaninstilbene Acid and Its Derivatives.

Wei-Min Chen, Zhi-Zhong Geng, Ping-Hua Sun, 2016, Journal of agricultural and food chemistry.

Iodine‐Catalyzed Azidation/Cyclization Cascade Approach to 3a‐Azidofuroindolines and ‐pyrroloindolines under Mild Conditions

Wei-Min Chen, Jialiang Guo, Q. Cai, 2017 .

A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells

W. Ye, Wei-Min Chen, Dong-Mei Zhang, 2016, Journal of Experimental & Clinical Cancer Research.

Design, synthesis and biological evaluation of 2-substituted 3-hydroxy-6-methyl-4H-pyran-4-one derivatives as Pseudomonas aeruginosa biofilm inhibitors.

Jia-hui Yu, Wei-Min Chen, Ping-Hua Sun, 2018, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel 5-hydroxy-2-methyl-4H-pyran-4-one derivatives as antiglioma agents.

Wei-Min Chen, Ping-Hua Sun, Jing Lin, 2018, MedChemComm.

Hybrids of arenobufagin and benzoisoselenazol reducing the cardiotoxicity of arenobufagin.

Wei-Min Chen, Dong-Mei Zhang, Ping-Hua Sun, 2018, Bioorganic & medicinal chemistry letters.

Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth

Jin-jian Lu, Q. Qi, W. Ye, 2020, Signal Transduction and Targeted Therapy.

Design and synthesis of caffeic acid derivatives and evaluation of their inhibitory activity against Pseudomonas aeruginosa

H. Zhou, Wei-Min Chen, Yunpeng Zeng, 2022, Medicinal Chemistry Research.

Design and synthesis of caffeic acid derivatives and evaluation of their inhibitory activity against Pseudomonas aeruginosa

H. Zhou, Wei-Min Chen, Yunpeng Zeng, 2022, Medicinal Chemistry Research.

Novel 4-(4-substituted amidobenzyl)furan-2(5H)-one derivatives as topoisomerase I inhibitors.

Wei-Min Chen, Cheng-Kang Peng, Xing-Jun Xu, 2017, European journal of medicinal chemistry.

Exploring 3D-QSAR for Ketolide Derivatives as Antibacterial Agents Using CoMFA and CoMSIA

Wei-Min Chen, Ping-Hua Sun, Qiuling Song, 2010 .

B5H7, a Morpholine Derivative of 23-Hydroxybetulinic Acid, Reverses Doxorubicin Resistance in HepG2/ADM

Zhe-Sheng Chen, W. Ye, Wei-Min Chen, 2014 .

New Pqs Quorum Sensing System Inhibitor as an Antibacterial Synergist against Multidrug-Resistant Pseudomonas aeruginosa.

Wei-Min Chen, Jinsong Hou, Ping-Hua Sun, 2021, Journal of medicinal chemistry.

Drug Design, Development and Therapy Dovepress Synthesis and Antibacterial Activities of Acylide Derivatives Bearing an Aryl-tetrazolyl Chain Ping-hua Sun

Shufeng Zhou, Jiazhi Sun, Wei-Min Chen, 2022 .

Novel securinine derivatives as topoisomerase I based antitumor agents.

Wei-Min Chen, Zhen-Ya Wang, Jun Xu, 2016, European journal of medicinal chemistry.

Molecular modeling studies on 3,4-dihydroquinazolines as trypanothione reductase inhibitors using 3D-QSAR and docking approaches

Wei-Min Chen, Zhi-Xiong Ruan, De-Sheng Huangfu, 2012, Medicinal Chemistry Research.

Identification of the HECT domain binding of indole-3-carbinol (I3C) derivatives for breast cancer therapy

Yuyang Jiang, Cunlong Zhang, Lei Zhao, 2023, Phytochemistry Letters.

Design, synthesis and anti-inflammatory effects of novel 9-O-substituted-berberine derivatives

Wei-Min Chen, Ping-Hua Sun, Jiajing Guo, 2016 .

Novel benzyl phenyl sulfide derivatives as antibacterial agents against methicillin-resistant Staphylococcus aureus

Wei-Min Chen, Jing Lin, Kuo Lu, 2019, The Journal of Antibiotics.

Understanding the structure-activity relationship of betulinic acid derivatives as anti-HIV-1 agents by using 3D-QSAR and docking

P. Lan, Wan-Na Chen, Wei-Min Chen, 2011, Journal of molecular modeling.

Design and Synthesis of 3-Hydroxy-pyridin-4(1H)-ones-Ciprofloxacin Conjugates as Dual Antibacterial and Antibiofilm Agents against Pseudomonas aeruginosa.

Yuan Wang, Wei-Min Chen, Jing Lin, 2023, Journal of medicinal chemistry.

Design and synthesis of 2‐hydroxyl‐4‐methoxyl‐3‐(3‐methylbut‐2‐en‐1‐yl)‐6‐(4‐phenylbenzoylamino)benzoic acid derivatives as antibacterial agents based on cajaninstilbene acid scaffold hopping

Wei-Min Chen, Ping-Hua Sun, Jing Lin, 2019, Drug development research.

A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells

W. Ye, Wei-Min Chen, Dong-Mei Zhang, 2016, Journal of experimental & clinical cancer research : CR.

Molecular modeling studies on 3,4-dihydroquinazolines as trypanothione reductase inhibitors using 3D-QSAR and docking approaches

Wei-Min Chen, Zhi-Xiong Ruan, De-Sheng Huangfu, 2013, Medicinal Chemistry Research.

Molecular modelling studies on d-annulated benzazepinones as VEGF-R2 kinase inhibitors using docking and 3D-QSAR

P. Lan, Wan-Na Chen, Wei-Min Chen, 2011, Journal of enzyme inhibition and medicinal chemistry.

3D-QSAR studies and molecular docking on [5-(4-amino-1H-benzoimidazol-2-yl)-furan-2-yl]-phosphonic acid derivatives as fructose-1,6-biphophatase inhibitors

Wei-Min Chen, Ping Lan, Mei-Qi Xie, 2010, J. Comput. Aided Mol. Des..

Cajaninstilbene acid analogues as novel quorum sensing and biofilm inhibitors of Pseudomonas aeruginosa.

Jia-hui Yu, Wei-Min Chen, Xing-Jun Xu, 2020, Microbial pathogenesis.

Design, synthesis and biological evaluation of novel 3-hydroxypyridin-4(1H)-ones based hybrids as Pseudomonas aeruginosa biofilm inhibitors.

Wei-Min Chen, Ping-Hua Sun, Mingming Yang, 2023, European journal of medicinal chemistry.

3-Hydroxy-pyridin-4(1H)-ones as siderophores mediated delivery of isobavachalcone enhances antibacterial activity against pathogenic Pseudomonas aeruginosa.

Wei-Min Chen, Ming Yang, Jing Lin, 2023, European journal of medicinal chemistry.

A fluorescence-based high-throughput screening method for determining the activity of diguanylate cyclases and c-di-GMP phosphodiesterases

Wei-Min Chen, Jing Lin, Jun Liu, 2020, RSC advances.

Two pairs of new benzofuran enantiomers with unusual skeletons from Eupatorium chinense

Lei Wang, W. Ye, Xiao‐Jun Huang, 2013 .

Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms.

Jia-hui Yu, Wei-Min Chen, Jing Lin, 2021, European journal of medicinal chemistry.

3D-QSAR and molecular docking studies of azaindole derivatives as Aurora B kinase inhibitors

P. Lan, Wan-Na Chen, Wei-Min Chen, 2011, Journal of molecular modeling.

Betulinic Acid and its Derivatives as Potential Antitumor Agents

Lei Wang, W. Ye, Wei-Min Chen, 2015, Medicinal research reviews.

Strigolactones: a plant phytohormone as novel anti-inflammatory agents.

Wei-Min Chen, Jialiang Guo, Ping-Hua Sun, 2018, MedChemComm.

Correction: Design, synthesis and anti-inflammatory effects of novel 9-O-substituted-berberine derivatives electronic supplementary information

Wei-Min Chen, Ping-Hua Sun, Jiajing Guo, 2016 .