P. Mann

发表

Selective small-molecule inhibition of an RNA structural element

John J. Cummings, T. Roemer, T. Fischmann, 2015, Nature.

Mapping and Characterization of Vicriviroc Resistance Mutations From HIV-1 Isolated from Treatment-Experienced Subjects Enrolled in a Phase II Study (VICTOR-E1)

P. Mann, P. McNicholas, J. Strizki, 2011, Journal of acquired immune deficiency syndromes.

Discovery of potent wall teichoic acid early stage inhibitors.

T. Roemer, S. Koseoglu, C. Garlisi, 2016, Bioorganic & medicinal chemistry letters.

TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci

T. Roemer, Xinwei Sher, S. Koseoglu, 2016, Science Translational Medicine.

In Vitro Activities of Posaconazole, Fluconazole, Itraconazole, Voriconazole, and Amphotericin B against a Large Collection of Clinically Important Molds and Yeasts

D. Loebenberg, P. Mann, C. Mendrick, 2006, Antimicrobial Agents and Chemotherapy.

EmtA, a rRNA methyltransferase conferring high‐level evernimicin resistance

F. Aarestrup, A. Mankin, R. Goering, 2001, Molecular microbiology.

Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

P. Mann, P. McNicholas, R. Hare, 2001, Antimicrobial Agents and Chemotherapy.

Analysis of β‐glucans and chitin in a Saccharomyces cerevisiae cell wall mutant using high‐performance liquid chromatography

B. Didomenico, K. Shaw, P. Mann, 1994 .

Cloning and Characterization of KNR4, a Yeast Gene Involved in (1,3)-13-Glucan Synthesis

Z. Hong, B. Didomenico, K. Shaw, 2022 .

Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species

P. Mann, C. Mendrick, Reena Patel, 2009, Antimicrobial Agents and Chemotherapy.

Neutralization of Pathogenic Fungi with Small-Molecule Immunotherapeutics.

T. Roemer, E. Chirkin, P. Nantermet, 2017, Angewandte Chemie.

Synthesis and antifungal evaluation of pentyloxyl-diphenylisoxazoloyl pneumocandins and echinocandins.

M. Motyl, P. Mann, Sheo B. Singh, 2013, Bioorganic & medicinal chemistry letters.

Cloning and characterization of KNR4, a yeast gene involved in (1,3)-beta-glucan synthesis

B. Didomenico, N. Brown, K. Shaw, 1994, Molecular and cellular biology.

Multiple Resistance Mechanisms among Aspergillus fumigatus Mutants with High-Level Resistance to Itraconazole

G. Goldman, M. Dudley, D. Perlin, 2003, Antimicrobial Agents and Chemotherapy.

Correlation between aminoglycoside resistance profiles and DNA hybridization of clinical isolates

S. Kocsi, K. Shaw, P. Mann, 1991, Antimicrobial Agents and Chemotherapy.

Characterization of the chromosomal aac(6')-Ic gene from Serratia marcescens

P. Rather, G. Petrikkos, K. Shaw, 1992, Antimicrobial Agents and Chemotherapy.

Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds

D. Loebenberg, J. Greene, R. Palermo, 2004, Antimicrobial Agents and Chemotherapy.

Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole.

L. Wheat, P. Mann, Reena Patel, 2006, The Journal of antimicrobial chemotherapy.

Mutations in Aspergillus fumigatus Resulting in Reduced Susceptibility to Posaconazole Appear To Be Restricted to a Single Amino Acid in the Cytochrome P450 14α-Demethylase

D. Loebenberg, B. Didomenico, P. Mann, 2003, Antimicrobial Agents and Chemotherapy.

Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis

C. Boone, S. Lindquist, M. Costanzo, 2014, ACS infectious diseases.

Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae

P. Mann, P. McNicholas, Andrew S. Chau, 2006, Antimicrobial Agents and Chemotherapy.

Murgocil is a highly bioactive staphylococcal-specific inhibitor of the peptidoglycan glycosyltransferase enzyme MurG.

P. M. Pereira, F. Monsma, T. Roemer, 2013, ACS chemical biology.

Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents.

T. Roemer, Timothy C. Meredith, S. Walker, 2013, Chemistry & biology.

Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins

P. Rather, K. Shaw, P. Mann, 1992, Journal of bacteriology.

Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

K. Shaw, P. Mann, P. McNicholas, 2000, Antimicrobial Agents and Chemotherapy.

, David Gram-Positive and Gram-Negative Bacteria in Cell-Free Systems Derived from both Ribosomal Subunit and Inhibits Translation Evernimicin Binds Exclusively to the 50 S

K. Shaw, P. Mann, P. McNicholas, 2000 .

Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.

T. Roemer, Xinwei Sher, J. Howe, 2017, Cell chemical biology.

Inhibitor of intramembrane protease RseP blocks the σE response causing lethal accumulation of unfolded outer membrane proteins

T. Roemer, T. Silhavy, N. W. Rigel, 2018, Proceedings of the National Academy of Sciences.

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

T. Roemer, Xinwei Sher, G. Scapin, 2017, PloS one.

Discovery and optimization of antibacterial AccC inhibitors.

Zhiwei Yang, P. Orth, P. Mann, 2009, Bioorganic & medicinal chemistry letters.

Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

C. Müller, T. Roemer, Xinwei Sher, 2016, PLoS pathogens.

Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors

R. J. Herr, P. Mann, S. Walker, 2011, Antimicrobial Agents and Chemotherapy.

Analysis of the aac(3)-VIa gene encoding a novel 3-N-acetyltransferase

P. Rather, K. Shaw, P. Mann, 1993, Antimicrobial Agents and Chemotherapy.

Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis

C. Boone, S. Lindquist, M. Costanzo, 2014, ACS infectious diseases.

In Vitro Activities of Posaconazole, Fluconazole, Itraconazole, Voriconazole, and Amphotericin B against a Large Collection of Clinically Important Molds and Yeasts

D. Loebenberg, P. Mann, C. Norris, 2006, Antimicrobial Agents and Chemotherapy.

Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species

P. Mann, Reena Patel, O. Cornely, 2009, Antimicrobial Agents and Chemotherapy.