W. Pan

发表

Selective small-molecule inhibition of an RNA structural element

John J. Cummings, T. Roemer, T. Fischmann, 2015, Nature.

Benzimidazole analogs as WTA biosynthesis inhibitors targeting methicillin resistant Staphylococcus aureus.

T. Roemer, S. Koseoglu, Jianping Pan, 2016, Bioorganic & medicinal chemistry letters.

Identification of inhibitors of UDP-galactopyranose mutase via combinatorial in situ screening.

W. Pan, Jun-Jun Cao, Yufen Xia, 2021, Organic & biomolecular chemistry.

Identification of inhibitors targeting Mycobacterium tuberculosis cell wall biosynthesis via dynamic combinatorial chemistry.

L. Kremer, W. Pan, M. Dieu, 2017, Chemical communications.

A novel base-induced isomerization gives access to unprecedented (E)-exo-glycals.

G. Eppe, W. Pan, Lidia Dumitrescu, 2013, Chemistry.

Synthesis of acyclic galactitol- and lyxitol-aminophosphonates as inhibitors of UDP-galactopyranose mutase

W. Pan, S. Vincent, Christophe Ansiaux, 2007 .

Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA

Song Wu, W. Pan, Tianlei Li, 2019, RSC advances.

Aromatic-carbohydrate interactions: an NMR and computational study of model systems.

S. Vandenbussche, F. Cañada, K. Bartik, 2008, Chemistry.

Vulgarisins B–D, three novel diterpenoids with a rare skeleton isolated from Prunella vulgaris Linn

W. Pan, Hua-yong Lou, Dao-ping Wang, 2017 .

Vulgarisin A, a new diterpenoid with a rare 5/6/4/5 ring skeleton from the Chinese medicinal plant Prunella vulgaris.

X. Hao, W. Pan, Shang-zhen Zheng, 2014, Organic letters.

Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors.

X. Tong, R. Doll, Zhuyan Guo, 2010, Bioorganic & medicinal chemistry letters.

Hepatitis C virus NS3-4A serine protease inhibitors: SAR of new P1 derivatives of SCH 503034.

A. Arasappan, F. G. Njoroge, W. Pan, 2008, Bioorganic & medicinal chemistry letters.

Synthesis of Unprecedented Sulfonylated Phosphono-exo-Glycals Designed as Inhibitors of the Three Mycobacterial Galactofuranose Processing Enzymes.

T. Lowary, W. Pan, R. Zheng, 2016, Chemistry.

Selectfluor and NFSI exo-glycal fluorination strategies applied to the enhancement of the binding affinity of galactofuranosyltransferase GlfT2 inhibitors.

G. Besra, G. Eppe, A. Ardá, 2014, Chemistry.

β-Stereoselective phosphorylations applied to the synthesis of ADP- and polyprenyl-β-mannopyranosides.

W. Pan, Tianlei Li, A. Tikad, 2014, Organic letters.

Inhibiting the formation of advanced glycation end-products by three stilbenes and the identification of their adducts.

W. Pan, Ai-Qun Jia, Yun Wu, 2019, Food chemistry.

Process development of clinical anti-HBV drug Y101: identification and synthesis of novel impurities

W. Pan, Changxiao Liu, Bixue Xu, 2016, Research on Chemical Intermediates.

Metallaphotoredox-catalyzed C–H activation: regio-selective annulation of allenes with benzamide

Xueyao Li, Song Wu, W. Pan, 2021 .

Design, synthesis and antibacterial evaluation of pleuromutilin derivatives.

Song Wu, W. Pan, J. Xia, 2022, Bioorganic & medicinal chemistry.

Synthesis of a deuterated analogue of bacteriohopanetetrol-glucosamine, a probe of complex hopanoid biosynthesis.

W. Pan, S. Vincent, 2008, Organic & biomolecular chemistry.

Complex biohopanoids synthesis: efficient anchoring of ribosyl subunits onto a C(30) hopane.

Yongming Zhang, W. Pan, S. Vincent, 2007, Chemistry.

A General Strategy to Synthesize ADP-7-Azido-heptose and ADP-Azido-mannoses and Their Heptosyltransferase Binding Properties.

E. Taylor, W. Pan, Tianlei Li, 2021, Organic letters.

Multigram-scale synthesis of l,d-heptoside using a Fleming-Tamao oxidation promoted by mercuric trifluoroacetate.

W. Pan, M. Durka, Tianlei Li, 2016, Carbohydrate research.

Stereocontrolled β- and α-Phosphorylations of d-Mannose

W. Pan, Y. Brissonnet, Tianlei Li, 2015 .

Strategy of tobacco plant against black shank and tobacco mosaic virus infection via induction of PR-1, PR-4 and PR-5 proteins assisted by medicinal plant extracts

Qingchang Li, W. Pan, M. Zheng, 2017 .

Synthesis of galactosides locked in a 1,4B boat conformation and functionalized at the anomeric position

J. Kovensky, W. Pan, A. Caravano, 2007 .

Perinerin, a novel antimicrobial peptide purified from the clamworm Perinereis aibuhitensis grube and its partial characterization.

F. Ge, W. Pan, Xiang-hui Liu, 2004, Journal of biochemistry.

Metallaphotoredox-catalyzed C–H activation: regio-selective annulation of allenes with benzamide

Xueyao Li, Song Wu, W. Pan, 2020, Organic Chemistry Frontiers.

One-Step Synthesis of Diverse Pyridine-Containing Heterocycles with 3-Ethoxycyclobutanones at Room Temperature.

W. Pan, Xinglin Yang, Yu Rao, 2016, Organic letters.

Synthesis and Biological Evaluation of Matijin‐Su Derivatives as Potential Antihepatitis B Virus and Anticancer Agents

W. Pan, Changxiao Liu, Bixue Xu, 2016, Chemistry & biodiversity.

Synthesis and biological evaluation of Matijing-Su derivatives as potent anti-HBV agents.

X. Hao, B. Song, W. Pan, 2011, Bioorganic & medicinal chemistry.

Synthesis and anti-hepatitis B virus activities of Matijing-Su derivatives.

X. Hao, W. Pan, Changxiao Liu, 2009, Bioorganic & medicinal chemistry.

A simple approach for the syntheses of rutaecarpine and its analogs

W. Pan, Mei Xu, Xiao-jiang Hao, 2015 .

Iodine Mediated Base‐Controlled Regio‐Selective Annulation of 2‐(Pyridin‐2‐yl)acetate Derivatives with Acrylic Esters for the Synthesis of Indolizines

W. Pan, Yuzhu Yang, Xiaolang Liu, 2020 .

SALEN-TI(OR)4 COMPLEX CATALYSED TRIMETHYLSILYLCYANATION OF ALDEHYDES

Zhi Li, W. Pan, L. Gong, 1997 .

Iodine-mediated one-pot synthesis of C-3 acylated indolizines from pyridines, aryl methyl ketones and acrylate derivatives

W. Pan, Yuzhu Yang, Fang Youlai, 2019, Tetrahedron.

Iodine-Mediated Oxidative Cyclization of 2-(Pyridin-2-yl)acetate Derivatives with Alkynes: Condition-Controlled Selective Synthesis of Multisubstituted Indolizines

Daoping Wang, W. Pan, Yuzhu Yang, 2020, Synthesis.

Cobalt-catalyzed C–H activation and regioselective intermolecular annulation with allenes

W. Pan, Yu Rao, Chao Zhang, 2017 .

The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.

Zhuyan Guo, Frank Bennett, X. Tong, 2010, Bioorganic & medicinal chemistry letters.

Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species.

R. Doll, Zhuyan Guo, A. Arasappan, 2010, Bioorganic & medicinal chemistry.

Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor:

Weiying Yang, Zhuyan Guo, Andrea Hart, 2006, Journal of medicinal chemistry.

Controllable Synthesis of Polyheterocyclic Spirooxindoles and 3,3‐Bistryptophol Oxindoles via Fe(ClO 4 ) 3 ⋅ 6H 2 O‐Promoted Hetero‐Pictet‐Spengler Reaction

W. Pan, Juan Chen, Zhanglin Ni, 2020 .

Asymmetric Synthesis XXIV: Chiral Salen-Titanium Complexes-Efficient Catalysts for Asymmetric Trimethyl Silylcyanation of Benzaldehyde

Zhi Li, Zhibo Li, W. Pan, 1996 .

Syntheses and anti-cancer activities of glycosylated derivatives of diosgenin

Y. Ben-David, W. Pan, Heng Luo, 2017, Chemical Research in Chinese Universities.

A novel iridoid from Torricellia angulata var intermedia

X. Hao, W. Pan, Yang Lu, 2009, Natural product research.

Two new naturally occurring optical polyacetylene compounds from Torricellia angulata var intermedia and the determination of their absolute configurations

Yongming Zhang, W. Pan, Bixue Xu, 2006, Natural product research.

New Germacrane-sesquiterpenoids from the leaves of Mikania micrantha Kunth

W. Pan, Jinyu Li, Zhaoguo Wang, 2020 .

Colorimetric Assay to Determine In Vitro Antibacterial Activity Against Clinical Isolates: Enhanced Activity in Damaged Chinese Masson Pine Needles

Gong-she Liu, W. Pan, Xiang-hui Liu, 2006 .

Natural and Synthetic Flavonoids as Potent Mycobacterium tuberculosis UGM Inhibitors.

L. Kremer, W. Pan, Hua-yong Lou, 2017, Chemistry.

Aminoglycoside complexation with a DNA.RNA hybrid duplex: the thermodynamics of recognition and inhibition of RNA processing enzymes.

Roger A. Jones, B. Gaffney, D. S. Pilch, 2003, Journal of the American Chemical Society.

Diastereoselective Synthesis of Aminobacteriohopanetetrol, a Biomarker for Methanotrophic Bacteria: Confirmation of the Absolute Configuration

M. Rohmer, Yongming Zhang, W. Pan, 2007, Chemistry and Biodiversity.

Synthesis of spiro[4.4]nonane-1,6-diols via the hydrogenation of spiro[4.4]nonane-1,6-dione: the profound effect of hydrogenating agents

Jian Sun, A. Chan, Zhi Li, 1995 .

Diastereoselective Synthesis of Aminobacteriohopanetetrol, a Biomarker for Methanotrophic Bacteria: Confirmation of the Absolute Configuration

M. Rohmer, Yongming Zhang, W. Pan, 2007, Chemistry & biodiversity.

Concise syntheses of bacteriohopanetetrol and its glucosamine derivative.

Yongming Zhang, W. Pan, S. Vincent, 2005, Chemical communications.

Novel N-oxide derivatives of benzyltetrahydroisoquinoline alkaloid from the tubers of Stephania viridiflavens H.S. Lo et M. Yang

W. Pan, Mao-sheng Zhang, Qian-yun Sun, 2012 .

Aporphine alkaloids from the roots of Stephania viridiflavens

W. Pan, Mao-sheng Zhang, Guang-yi Liang, 2010, Natural product research.

Pyruvate‐Kinase‐Coupled Glycosyltransferase Assays: Limitations, Struggles and Problem Resolution

W. Pan, S. Vincent, Huixiao Fu, 2017, Chembiochem : a European journal of chemical biology.

Phe19 Modification of HDM2-p53 PPI Inhibitors to Alleviate CYP3A4 Metabolism/Mechanism-based Inhibition Liability.

Yaolin Wang, T. Guzi, R. Doll, 2022, Bioorganic & medicinal chemistry letters.

Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor.

Weiying Yang, Frank Bennett, Jesse Wong, 2010, ACS medicinal chemistry letters.

Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.

S. Tamura, S. Kemp, M. Lim-Wilby, 2006, Journal of medicinal chemistry.

Diverse Flavonoids from the Roots of Indigofera stachyodes

X. Hao, W. Pan, Hua-yong Lou, 2022, Chemistry & biodiversity.

A novel franchetine type norditerpenoid isolated from the roots of Aconitum carmichaeli Debx. with potential analgesic activity and less toxicity.

W. Pan, Xiao-jiang Hao, Hua-yong Lou, 2012, Bioorganic & Medicinal Chemistry Letters.

A Novel Franchetine Type Norditerpenoid Isolated from the Roots of Aconitum carmichaeli Debx. with Potential Analgesic Activity and Less Toxicity

W. Pan, Xiao-jiang Hao, Hua-yong Lou, 2012 .

Second-generation highly potent and selective inhibitors of the hepatitis C virus NS3 serine protease.

Weiying Yang, Frank Bennett, X. Tong, 2009, Journal of medicinal chemistry.

The dynamics of tocopherol and the effect of high temperature in developing sunflower (Helianthus annuus L.) embryo

Gong-she Liu, Xiaoli Liu, W. Pan, 2007 .

Core modification of substituted piperidines as novel inhibitors of HDM2-p53 protein-protein interaction.

Yaolin Wang, R. Doll, B. Lahue, 2014, Bioorganic & medicinal chemistry letters.

C21 Steroidal Glycosides from Prunella vulgaris

Jie Pan, W. Pan, Shang-zhen Zheng, 2015 .

A New Ecdysteroidal Glycoside from Lepidogrammitis drymoglossoides (Bak.) Ching

W. Pan, Hua-yong Lou, Guang-yi Liang, 2014 .

Two New Flavonoids fromDerris eriocarpaHow

W. Pan, Hua-yong Lou, Guang-yi Liang, 2016 .

Design of Orally-bioavailable Tetra-cyclic phthalazine SOS1 inhibitors with high selectivity against EGFR.

Huan He, Silong Zhang, W. Pan, 2023, Bioorganic chemistry.

2′-Modified Guanosine Analogs for the Treatment of HCV

Q. Dang, A. Stamford, Vishal A. Verma, 2016, Nucleosides, Nucleotides & Nucleic Acids.

Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization

W. Pan, Sheng Liu, Chao Yang, 2016, Beilstein journal of organic chemistry.

Synthesis and evaluation of inhibitors of Mycobacterium tuberculosis UGM using bioisosteric replacement.

W. Pan, Jing-De Wu, Hua-yong Lou, 2022, Bioorganic & Medicinal Chemistry.

Toward the back-up of boceprevir (SCH 503034): discovery of new extended P4-capped ketoamide inhibitors of hepatitis C virus NS3 serine protease with improved potency and pharmacokinetic profiles.

Zhuyan Guo, Frank Bennett, Sumei Ruan, 2009, Journal of medicinal chemistry.

Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.

W. R. Bishop, D. Hicklin, G. Scapin, 2016, ACS medicinal chemistry letters.

Two New Flavonoids from Derris eriocarpa How.

W. Pan, Junjie Lan, Hua-yong Lou, 2016 .

Synthesis and anti-tumor activity evaluation of Matijin-Su derivatives.

Ning Wang, Meifen Zhu, W. Pan, 2014, Bioorganic chemistry.

Silver-Catalyzed Chlorocyclization for the Synthesis of 3-Chloro-2H-chromenes.

Yunhao Tang, W. Pan, Yuzhu Yang, 2023, The Journal of organic chemistry.

Tandem Approach to Functionalized Pyrrolo[3,4-a]carbazole-1,3-diones via a Pd-catalyzed Indole-to-carbazole Transformation

W. Pan, Mei Xu, Liang-Qi Guo, 2019, Chemical Research in Chinese Universities.

Vulgarisin-type diterpenoids from self-heal (Prunella vulgaris) and their neuroprotective effects against ischemia/reperfusion (I/R) via a mitochondria-related pathway.

W. Pan, Wenneng Wu, Hua-yong Lou, 2022, Food & function.

2′-Modified Guanosine Analogs for the Treatment of HCV

Q. Dang, A. Stamford, Vishal A. Verma, 2016, Nucleosides, nucleotides & nucleic acids.