C. Gill

发表

Selective small-molecule inhibition of an RNA structural element

John J. Cummings, T. Roemer, T. Fischmann, 2015, Nature.

Ibrexafungerp: an orally active β-1,3-glucan synthesis inhibitor.

P. Liberator, M. Motyl, M. Peel, 2020, Bioorganic & medicinal chemistry letters.

MK-5204: An orally active β-1,3-glucan synthesis inhibitor.

P. Liberator, M. Motyl, M. Peel, 2020, Bioorganic & medicinal chemistry letters.

Quantitation of wall teichoic acid in Staphylococcus aureus by direct measurement of monomeric units using LC-MS/MS.

D. McLaren, Hao Wang, P. Sheth, 2017, Analytical biochemistry.

TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci

T. Roemer, Xinwei Sher, S. Koseoglu, 2016, Science Translational Medicine.

In Vivo Activity and Pharmacokinetic Evaluation of a Novel Long-Acting Carbapenem Antibiotic, MK-826 (L-749,345)

B. Pelak, C. Gill, H. Rosen, 1998, Antimicrobial Agents and Chemotherapy.

In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)

J. Smith, J. Balkovec, P. Scott, 1997, Antimicrobial agents and chemotherapy.

A sensitive and specific PCR method to detect Helicobacter felis in a conventional mouse model

J. Smith, P. Scott, C. Gill, 1996, Clinical and diagnostic laboratory immunology.

Inactivation of Kex2p Diminishes the Virulence of Candida albicans *

Julie J. Blake, A. Kuo, N. Agabian, 2003, The Journal of Biological Chemistry.

In Vivo Efﬁcacy of a Novel Oxazolidinone Compound in Two Mouse Models of Infection (cid:1)

C. Gill, K. Bartizal, A. Flattery, 2007 .

Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347.

Scott K. Smith, F. Vicente, Ó. Salazar, 2008, Journal of the American Chemical Society.

Antibacterial evaluations of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa.

M. Motyl, C. Gill, Sheo B. Singh, 2008, Journal of antibiotics (Tokyo. 1968).

Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin.

P. Liberator, M. Motyl, M. Peel, 2015, Bioorganic & medicinal chemistry letters.

Experimental Oropharyngeal and Gastrointestinal Candida Infection in Mice

C. Gill, K. Bartizal, A. Flattery, 1999 .

In vitro evaluation of the pneumocandin antifungal agent L-733560, a new water-soluble hybrid of L-705589 and L-731373

C. Gill, K. Bartizal, G. Abruzzo, 1995, Antimicrobial agents and chemotherapy.

Efficacy of Caspofungin against Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans

P. Liberator, B. Pelak, C. Gill, 2006, Antimicrobial Agents and Chemotherapy.

In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase

Akinori Nishimura, Jin Wu, C. Garlisi, 2016, Antimicrobial Agents and Chemotherapy.

A Potent Thiazolyl Peptide Antibiotic from Amycolatopsis fastidiosa

M. Motyl, C. Gill, Sheo B. Singh, 2009 .

Antibacterial Evaluations of Thiazomycin

M. Motyl, C. Gill, Sheo B. Singh, 2007, The Journal of Antibiotics.

Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

J. Smith, J. Balkovec, C. Gill, 1997, Antimicrobial agents and chemotherapy.

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, Olga Genilloud, Sang Ho Lee, 2006, Nature.

PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products.

Yang Li, Li Zhang, Guy Harris, 2008, Chemistry & biology.

Antifungal spectrum, in vivo efficacy, and structure-activity relationship of ilicicolin h.

V. Hornak, C. Gill, Sheo B. Singh, 2012, ACS medicinal chemistry letters.

Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic.

H. Rosen, J. Heck, J. Kozarich, 1999, Science.

Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to β-Lactam Antibiotics

Eric Langlois, Alexandre Caron, Mihai Petcu, 2012, Science Translational Medicine.

L-658,310, a new injectable cephalosporin. I. In vitro antibacterial properties.

R. Fromtling, B. Weissberger, C. Gill, 1989, The Journal of antibiotics.

Pharmacokinetics of L-749,345, a long-acting carbapenem antibiotic, in primates

C. Gill, H. Rosen, R. Hajdu, 1997, Antimicrobial agents and chemotherapy.

Elucidation of DnaE as the Antibacterial Target of the Natural Product, Nargenicin.

B. Nare, F. Vicente, D. Wisniewski, 2015, Chemistry & biology.

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis

J. Smith, C. Gill, K. Bartizal, 1995, Antimicrobial agents and chemotherapy.

Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice

C. Gill, K. Bartizal, H. Rosen, 2000, Antimicrobial Agents and Chemotherapy.

Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates

S. A. Parent, G. Chrebet, H. Teppler, 2005, Antimicrobial Agents and Chemotherapy.

Quantitative PCR Assay To MeasureAspergillus fumigatus Burden in a Murine Model of Disseminated Aspergillosis: Demonstration of Efficacy of Caspofungin Acetate

D. Schmatz, J. Anderson, P. Liberator, 2001, Antimicrobial Agents and Chemotherapy.

New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents

J. Smith, C. Gill, K. Bartizal, 1996, Antimicrobial agents and chemotherapy.

Efficacy of Caspofungin in a Juvenile Mouse Model of Central Nervous System Candidiasis

J. Ronan, Rena Zhang, Andrew M. Galgoci, 2011, Antimicrobial Agents and Chemotherapy.

Murgocil is a highly bioactive staphylococcal-specific inhibitor of the peptidoglycan glycosyltransferase enzyme MurG.

P. M. Pereira, F. Monsma, T. Roemer, 2013, ACS chemical biology.

Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents.

T. Roemer, Timothy C. Meredith, S. Walker, 2013, Chemistry & biology.

Use of Translational Pharmacokinetic/Pharmacodynamic Infection Models To Understand the Impact of Neutropenia on the Efficacy of Tedizolid Phosphate

S. Flanagan, Jin Wu, C. Gill, 2018, Antimicrobial Agents and Chemotherapy.

Comparative in vitro activity of norfloxacin against resistantNeisseria gonorrhoeae

C. Gill, D. Shungu, S. Ponticas, 1989, European Journal of Clinical Microbiology and Infectious Diseases.

Bactericidal activities of chloramphenicol and eleven other antibiotics against Salmonella spp

C. Gill, J. Campos, S. Preblud, 1984, Antimicrobial Agents and Chemotherapy.

Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin

Scott K. Smith, J. Phillips, F. Vicente, 2014, The Journal of Antibiotics.

In-vitro activity of imipenem against 100 strains of serotype b and nontypable Haemophilus influenzae, including strains resistant to ampicillin, chloramphenicol or both.

C. Gill, J. Campos, V. Ahonkhai, 1985, The Journal of antimicrobial chemotherapy.

Evaluation of experimental therapeutics in a new mouse model of Helicobacter felis utilizing 16S rRNA polymerase chain reaction for detection.

J. Smith, P. Scott, C. Gill, 1997, Scandinavian journal of gastroenterology.

PCR detection of colonization by Helicobacter pylori in conventional, euthymic mice based on the 16S ribosomal gene sequence

J. Smith, P. Scott, C. Gill, 1996, Clinical and diagnostic laboratory immunology.

Comparative susceptibilities of Campylobacter pylori to norfloxacin and other agents

D. Nalin, R. Gilman, B. Weissberger, 1987, Antimicrobial Agents and Chemotherapy.

Rustmicin, a Potent Antifungal Agent, Inhibits Sphingolipid Synthesis at Inositol Phosphoceramide Synthase*

M. Garcia-Calvo, H. Bull, C. Gill, 1998, The Journal of Biological Chemistry.

Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling

J. Phillips, F. Vicente, R. Donald, 2010, The Journal of Antibiotics.

Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.

T. Roemer, Xinwei Sher, J. Howe, 2017, Cell chemical biology.

Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor.

T. Roemer, S. Koseoglu, P. Tawa, 2017, Journal of medicinal chemistry.

In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin.

J. Smith, C. Gill, K. Bartizal, 1995, The Journal of antibiotics.

Use of translational PKPD infection models to understand impact of neutropenia on efficacy of tedizolid phosphate

Jin Wu, C. Gill, Jianying Xiao, 2017 .

Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets

C. Müller, T. Roemer, Xinwei Sher, 2016, PLoS pathogens.

Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3).

R. Nargund, Akinori Nishimura, Jin Wu, 2015, Bioorganic & medicinal chemistry letters.

In Vivo Efficacy of a Novel Oxazolidinone Compound in Two Mouse Models of Infection

C. Gill, K. Bartizal, A. Flattery, 2007, Antimicrobial Agents and Chemotherapy.

Caspofungin versus amphotericin B treatment of Aspergillus fumigatus in kidneys of chronically immunosuppressed infected mice

B. Pikounis, P. Liberator, C. Gill, 2005 .

Real-Time Monitoring of Bacterial Infection In Vivo: Development of Bioluminescent Staphylococcal Foreign-Body and Deep-Thigh-Wound Mouse Infection Models

Kathrin U. Jansen, Charles Gill, Kevin P. Francis, 2003, Antimicrobial Agents and Chemotherapy.

Experimental model of reversible myelosuppression caused by short-term, high-dose oxazolidinone administration

C. Gill, G. Abruzzo, A. Misura, 2006 .

Efﬁcacy of Caspofungin in a Juvenile Mouse Model of Central Nervous System Candidiasis (cid:1)

J. Ronan, Andrew M. Galgoci, C. Gill, 2011 .

Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3).

R. Nargund, Akinori Nishimura, Jin Wu, 2015, Bioorganic & medicinal chemistry letters.