R. Koehler

发表

Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype.

Thomas W. Mühleisen, T. Mühleisen, M. Nöthen, 2013, Blood.

A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1

M. Nöthen, James Allan, M. Greaves, 2016, Leukemia.

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study.

J. V. van Dongen, O. Haas, M. Schrappe, 2010, Blood.

Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients

L. Gautier, T. Sicheritz-Pontén, S. Brunak, 2014, Leukemia.

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

B. Meissner, A. Teigler‐Schlegel, J. Harbott, 2010, Haematologica.

leukemia : results in 3184 patients of the AIEOP-BFM ALL 2000 study children and adolescents with B-cell precursor acute lymphoblastic Molecular response to treatment redefines all prognostic factors in

O. Haas, C. Bartram, J. Dongen, 2010 .

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia

B. Schäfer, M. Schrappe, C. Bartram, 2008, Leukemia.

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse

T. Rausch, J. Korbel, A. Stütz, 2014, Haematologica.

Low frequency of BMPR2 mutations in a German cohort of patients with sporadic idiopathic pulmonary arterial hypertension

R. Ewert, B. Janssen, H. Olschewski, 2004, Journal of Medical Genetics.

Verification of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood.

E. Papaemmanuil, J. Vijayakrishnan, R. Houlston, 2010, Blood.

Polymorphism of Amyloid Fibrils In Vivo.

C. Sigurdson, M. Fändrich, U. Hegenbart, 2016, Angewandte Chemie.

NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia

M. Muckenthaler, M. Schrappe, W. Ludwig, 2013, Haematologica.

Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.

H. Lilie, M. Groll, M. Fändrich, 2017, Angewandte Chemie.

IKZF1plus Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.

D. Steinemann, M. Muckenthaler, R. Houlston, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment

M. Schrappe, C. Bartram, C. Eckert, 2011, Leukemia.

Enhanced hypoxic pulmonary vasoconstriction in families of adults or children with idiopathic pulmonary arterial hypertension.

B. Janssen, H. Olschewski, E. Grünig, 2005, Chest.

Serotonin transporter gene polymorphism in a cohort of German patients with idiopathic pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension.

B. Janssen, M. Hoeper, H. Olschewski, 2005, Chest.

Brief report Veriﬁcation of the susceptibility loci on 7p12.2, 10q21.2, and 14q11.2 in precursor B-cell acute lymphoblastic leukemia of childhood

E. Papaemmanuil, M. Greaves, J. Vijayakrishnan, 2010 .

Minimal residual disease in BCR::ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease

J. Stuchly, M. Trková, E. Froňková, 2022, Leukemia.

Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk

James Allan, E. Papaemmanuil, J. Vijayakrishnan, 2010, Nature Genetics.

Stress Doppler Echocardiography in Relatives of Patients With Idiopathic and Familial Pulmonary Arterial Hypertension: Results of a Multicenter European Analysis of Pulmonary Artery Pressure Response to Exercise and Hypoxia

M. Humbert, W. Seeger, A. Torbicki, 2009, Circulation.

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

Martin Zimmermann, Carl W. Miller, Rolf Koehler, 2008, Proceedings of the National Academy of Sciences.

The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL–BFM 2000 protocol can be separated from FBXW7 loss of function

M. Muckenthaler, M. Schrappe, W. Ludwig, 2010, Leukemia.

Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia.

B. Meissner, I. Heřmanová, A. Teigler‐Schlegel, 2014, Human molecular genetics.

Pediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation

V. Beneš, T. Rausch, J. Korbel, 2015, Haematologica.

childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study Late MRD response determines relapse risk overall and in subsets of

B. Schäfer, M. Schrappe, C. Bartram, 2013 .

Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome

B. Meissner, A. Teigler‐Schlegel, M. Schrappe, 2012, Haematologica.

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study.

J. V. van Dongen, B. Schäfer, M. Schrappe, 2011, Blood.

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray.

Carl W. Miller, S. Ogawa, K. Hemminki, 2007, Blood.

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia

B. Meissner, J. Stuchly, A. Teigler‐Schlegel, 2015, Leukemia.

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia

B. Meissner, J. Stuchly, A. Teigler‐Schlegel, 2014, Leukemia.

M. Muckenthaler, J. Vijayakrishnan, R. Houlston, 2023, Journal of Experimental & Clinical Cancer Research.

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia

E. Froňková, M. Schrappe, C. Bartram, 2016, British journal of haematology.

A genome-wide association study identi fi es risk loci for childhood acute lymphoblastic leukemia at 10 q 26 . 13 and 12 q 23 . 1

J. Vijayakrishnan, K. Hemminki, M. Greaves, 2017 .

Genetic association of the serotonin transporter in pulmonary arterial hypertension.

Eric W. Glissmeyer, J. Carlquist, W. Seeger, 2006, American journal of respiratory and critical care medicine.

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

M. Nöthen, R. Eeles, Z. Kote-Jarai, 2018, Nature Communications.

Large BRCA1 gene deletions are found in 3% of German high‐risk breast cancer families

C. Bartram, R. Klaes, B. Janssen, 2004, Human mutation.

The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A

Thomas W. Mühleisen, T. Mühleisen, M. Nöthen, 2015, Scientific Reports.

The 9 p 21 . 3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN 2 A

Thomas W. Mühleisen, T. Mühleisen, M. Nöthen, 2015 .

Mutations of the TGF‐β type II receptor BMPR2 in pulmonary arterial hypertension

J. Carlquist, M. Humbert, W. Seeger, 2006, Human mutation.

Hypoxia Pulmonary Arterial Hypertension : Results of a Multicenter European Analysis of Stress Doppler Echocardiography in Relatives of Patients With Idiopathic and Familial

Kathleen, M. Humbert, A. Torbicki, 2009 .

Primary Pulmonary Hypertension in Children May Have a Different Genetic Background Than in Adults

C. Bartram, H. Katus, B. Janssen, 2004, Pediatric Research.

Primary pulmonary hypertension may be a heterogeneous disease with a second locus on chromosome 2q31.

C. Bartram, H. Katus, B. Janssen, 2003, Journal of the American College of Cardiology.

The Strong Prognostic Effect of Concurrent Deletions of IKZF1 and PAX5, CDKN2A, CDKN2B or PAR1 in the Absence of ERG Deletions (IKZF1plus) in Pediatric Acute Lymphoblastic Leukemia Strongly Depends on Minimal Residual Disease Burden after Induction Treatment

R. Houlston, M. Yaspo, A. Teigler‐Schlegel, 2014 .

The Favorable Effect of Activating NOTCH1 Receptor Mutations On Long Term Outcome in T-ALL Is Treatment Related and Can Be Separated From NOTCH Pathway Activation by FBXW7 Loss of Function.

M. Muckenthaler, M. Schrappe, W. Ludwig, 2009 .