Joanne K. Hobbs

发表

Toward More Accurate Ancestral Protein Genotype–Phenotype Reconstructions with the Use of Species Tree-Aware Gene Trees

M. Gouy, V. Arcus, S. Gribaldo, 2014, Molecular biology and evolution.

On the origin and evolution of thermophily: reconstruction of functional precambrian enzymes from ancestors of Bacillus.

V. Arcus, R. Daniel, D. Saul, 2012, Molecular biology and evolution.

On the Temperature Dependence of Enzyme-Catalyzed Rates.

Adrian J Mulholland, Vickery L Arcus, Emily J Parker, 2016, Biochemistry.

Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model.

M. Wilcox, Joanne K. Hobbs, J. Freeman, 2011, The Journal of antimicrobial chemotherapy.

KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate

A. Boraston, K. Abe, J. Hehemann, 2016, Proceedings of the National Academy of Sciences.

Functional Analyses of Resurrected and Contemporary Enzymes Illuminate an Evolutionary Path for the Emergence of Exolysis in Polysaccharide Lyase Family 2*

A. Boraston, D. W. Abbott, Richard McLean, 2015, The Journal of Biological Chemistry.

Metabolism of a hybrid algal galactan by members of the human gut microbiome

Nitin, Xiaohui Xing, A. Boraston, 2022, Nature Chemical Biology.

XF-73, a novel antistaphylococcal membrane-active agent with rapid bactericidal activity.

I. Chopra, K. Miller, W. Love, 2009, The Journal of antimicrobial chemotherapy.

Article TowardMoreAccurateAncestralProteinGenotype-Phenotype Reconstructions with the Use of Species Tree-Aware Gene Trees

M. Gouy, V. Arcus, S. Gribaldo, 2014 .

Antistaphylococcal activity of the novel cephalosporin CB-181963 (CAB-175).

I. Chopra, K. Miller, Joanne K. Hobbs, 2005, The Journal of antimicrobial chemotherapy.

Molecular Characterization of Clinical Rel Mutations and Consequences for Resistance Expression and Fitness in Staphylococcus aureus

A. Boraston, Joanne K. Hobbs, Ashley T Deventer, 2022, Antimicrobial agents and chemotherapy.

(p)ppGpp and the Stringent Response: An Emerging Threat to Antibiotic Therapy.

A. Boraston, Joanne K. Hobbs, 2019, ACS infectious diseases.

Clinical Mutations That Partially Activate the Stringent Response Confer Multidrug Tolerance in Staphylococcus aureus

A. Boraston, Joanne K. Hobbs, A. Hettle, 2019, Antimicrobial Agents and Chemotherapy.

Consequences of daptomycin-mediated membrane damage in Staphylococcus aureus.

I. Chopra, K. Miller, A. O’Neill, 2008, The Journal of antimicrobial chemotherapy.

Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species

O. Salama-Alber, J. Hui, A. Boraston, 2019, Communications Biology.

Glycan‐metabolizing enzymes in microbe–host interactions: the Streptococcus pneumoniae paradigm

A. Boraston, Joanne K. Hobbs, B. Pluvinage, 2018, FEBS letters.

Biochemical Reconstruction of a Metabolic Pathway from a Marine Bacterium Reveals Its Mechanism of Pectin Depolymerization

A. Boraston, Joanne K. Hobbs, C. Vickers, 2018, Applied and Environmental Microbiology.

Reconstructed Ancestral Enzymes Impose a Fitness Cost upon Modern Bacteria Despite Exhibiting Favourable Biochemical Properties

E. Prentice, V. Arcus, M. Groussin, 2015, Journal of Molecular Evolution.

Molecular Characterization of N-glycan Degradation and Transport in Streptococcus pneumoniae and Its Contribution to Virulence

H. Brumer, H. Yesilkaya, A. Boraston, 2017, PLoS pathogens.

Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.

A. Boraston, Joanne K. Hobbs, Steven P. Smith, 2019 .

Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens

A. Boraston, Joanne K. Hobbs, Steven P. Smith, 2019, The Journal of Biological Chemistry.

Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed rates.

L. Schipper, V. Arcus, E. Parker, 2013, ACS chemical biology.

A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans*

A. Boraston, Joanne K. Hobbs, M. Higgins, 2015, The Journal of Biological Chemistry.

Thermodynamic theory explains the temperature optima of soil microbial processes and high Q10 values at low temperatures

L. Schipper, V. Arcus, S. Rutledge, 2014, Global change biology.

Evolution of extended-spectrum beta-lactamases in a MutS-deficient Pseudomonas aeruginosa hypermutator.

I. Chopra, K. Miller, J. Bostock, 2006, The Journal of antimicrobial chemotherapy.

Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species

O. Salama-Alber, J. Hui, A. Boraston, 2019, Communications Biology.

Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species

O. Salama-Alber, J. Hui, A. Boraston, 2019, Communications Biology.

Separation and Visualization of Glycans by Fluorophore-Assisted Carbohydrate Electrophoresis.

A. Boraston, Joanne K. Hobbs, M. Robb, 2017, Methods in molecular biology.

A surrogate structural platform informed by ancestral reconstruction and resurrection of a putative carbohydrate binding module hybrid illuminates the neofunctionalization of a pectate lyase.

D. W. Abbott, Richard McLean, Joanne K. Hobbs, 2019, Journal of structural biology.

On the Temperature Dependence of Enzyme-Catalyzed Rates.

L. Schipper, E. Prentice, V. Arcus, 2016, Biochemistry.

KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate

A. Boraston, K. Abe, J. Hehemann, 2016, Proceedings of the National Academy of Sciences.