C. Salinas

发表

The Simplified Reference Tissue Model: Model Assumption Violations and Their Impact on Binding Potential

G. Searle, R. Gunn, C. Salinas, 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Radiosynthesis and evaluation of 1-substituted 3-(2,3-dihydro-1H-inden-2-yl)-6-(1-ethylpropyl)-(3R,6R)-2,5-piperazinedione derivatives as PET tracers for imaging the central oxytocinergic system.

J. Passchier, S. Jakobsen, C. Plisson, 2017, Journal of labelled compounds & radiopharmaceuticals.

Robust experiment design for estimating myocardial beta adrenergic receptor concentration using PET.

P. Ernsberger, G. Saidel, R. F. Muzic, 2006, Medical physics.

Validity of model approximations for receptor-ligand kinetics in nuclear medicine.

G. Saidel, R. F. Muzic, C. Salinas, 2007, Medical physics.

Robust experimental design for estimating myocardial beta adrenergic receptor concentration using positron emission tomography.

C. Salinas, 2006 .

PET Imaging of Myocardial β-Adrenergic Receptors with Fluorocarazolol: Lack of Interference by Endogenous Catecholamines

P. Ernsberger, R. F. Muzic, C. Salinas, 2005, Journal of cardiovascular pharmacology.

A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway

G. Mills, H. Gabra, Rakesh Kumar, 2015, Oncotarget.

The role of P-glycoprotein on blood brain barrier permeability of [11C]Loperamide in humans

S. Houle, J. Passchier, M. Laruelle, 2008, NeuroImage.

Prediction of Repeat-Dose Occupancy from Single-Dose Data: Characterisation of the Relationship between Plasma Pharmacokinetics and Brain Target Occupancy

Stefano Zamuner, Roger N Gunn, Graham E Searle, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Dopamine D3 receptor antagonists: the quest for a potentially selective PET ligand. Part 3: Radiosynthesis and in vivo studies.

Yiyun Huang, M. Laruelle, R. Carson, 2009, Bioorganic & medicinal chemistry letters.

Comparison of [11C]PBR28 and [18F]FEPPA as CNS peripheral benzodiazepine receptor PET ligands in the pig

Alan A. Wilson, M. Laruelle, R. Gunn, 2008 .

Imaging Imidazoline-I2 Binding Sites in Porcine Brain Using 11C-BU99008

D. Nutt, A. Gee, S. Jakobsen, 2013, The Journal of Nuclear Medicine.

Effect of chronic antipsychotic treatment on striatal phosphodiesterase 10A levels: a [11C]MP-10 PET rodent imaging study with ex vivo confirmation

S. Kapur, S. Natesan, E. Rabiner, 2014, Translational Psychiatry.

11C-GSK189254: A Selective Radioligand for In Vivo Central Nervous System Imaging of Histamine H3 Receptors by PET

M. Laruelle, R. Gunn, A. Gee, 2009, Journal of Nuclear Medicine.

Dose-Finding Quantitative 18F-FDG PET Imaging Study with the Oral Pan-AKT Inhibitor GSK2141795 in Patients with Gynecologic Malignancies

Sabin Carme, Syed Babar, Cristian Salinas, 2015, The Journal of Nuclear Medicine.

Pharmacokinetic (PK)/pharmacodynamic (PD) analysis of escalating repeat doses of the AKT inhibitor GSK2141795 (GSK795) in patients (pts) with ovarian cancer.

R. Gunn, H. Gabra, R. Agarwal, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Preclinical Characterization of 18F-MK-6240, a Promising PET Tracer for In Vivo Quantification of Human Neurofibrillary Tangles

Talakad G. Lohith, L. Gantert, E. Hostetler, 2016, The Journal of Nuclear Medicine.

Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs).

Talakad G. Lohith, S. Melquist, L. Gantert, 2016, Journal of medicinal chemistry.

A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET

J. Seibyl, R. Gunn, M. Ichise, 2023, The Journal of Nuclear Medicine.

Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles

R. Vandenberghe, G. Bormans, E. Hostetler, 2018, The Journal of Nuclear Medicine.

A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET

Jessica A. Collins, J. Seibyl, R. Gunn, 2022, The Journal of Nuclear Medicine.

Test–retest characteristic of [18F]MK-6240 quantitative outcomes in cognitively normal adults and subjects with Alzheimer’s disease

C. Salinas, I. Bennacef, C. Sur, 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Radiosynthesis and Characterization of 11C-GSK215083 as a PET Radioligand for the 5-HT6 Receptor

Steen Jakobsen, Mark Slifstein, Marc Laruelle, 2012, The Journal of Nuclear Medicine.

Blood brain barrier permeability of [11C]loperamide in humans under normal and impaired P-glycoprotein function

Alan A. Wilson, S. Houle, J. Passchier, 2008 .

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: Dissection of D3 signal and anatomy

Mark Jenkinson, John D. Beaver, Marc Laruelle, 2011, NeuroImage.

Spatio-temporal pharmacokinetic model based registration of 4D PET neuroimaging data

Jieqing Jiao, Julia A. Schnabel, Roger N. Gunn, 2014, NeuroImage.

Advances in biomathematical modeling for PET neuroreceptor imaging.

Roger N Gunn, Qi Guo, Cristian A Salinas, 2011, Drug discovery today. Technologies.

Combining PET Biodistribution and Equilibrium Dialysis Assays to Assess the Free Brain Concentration and BBB Transport of CNS Drugs

Marc Laruelle, Roger N Gunn, Qi Guo, 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1

Mark Slifstein, Marc Laruelle, Stefano Zamuner, 2011, Synapse.

Quantitative systems pharmacology model for Alzheimer’s disease to predict the effect of aducanumab on brain amyloid

J. Burke, I. Nestorov, T. Bussiere, 2022, CPT: pharmacometrics & systems pharmacology.

Kinetic Analysis of Drug–Target Interactions with PET for Characterization of Pharmacological Hysteresis

Richard E Carson, David Weinzimmer, Roger N Gunn, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Monoamine Transporter Occupancy of a Novel Triple Reuptake Inhibitor in Baboons and Humans Using Positron Emission Tomography Clinical Imaging

Mark Slifstein, Marc Laruelle, Roger N Gunn, 2022 .

Preclinical Characterization of the Phosphodiesterase 10A PET Tracer [11C]MK-8193

I. Raheem, L. Gantert, E. Hostetler, 2016, Molecular Imaging and Biology.

Discovery of [11C]MK-6884: A Positron Emission Tomography (PET) Imaging Agent for the Study of M4 Muscarinic Receptor Positive Allosteric Modulators (PAMs) in Neurodegenerative Diseases.

Scott T. Harrison, M. Rudd, F. Monsma, 2020, Journal of medicinal chemistry.

Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A.

Richard E Carson, Steen Jakobsen, David Weinzimmer, 2011, Nuclear medicine and biology.

Evaluation of the adenosine A2A receptor ligand [11C] SCH442416 in the rodent brain

N. Keat, E. Rabiner, R. Gunn, 2013 .

Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

S. Kapur, R. Carson, D. Weinzimmer, 2014, The Journal of Nuclear Medicine.

Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with positron emission tomography

R N Gunn, M Laruelle, J. Passchier, 2010, Synapse.

A pseudo-reference region method applied to measurement of GlyT1 occupancy in human brain using [11C]GSK931145 and PET

Cristian Salinas, Marc Laruelle, Ana M. Catafau, 2010, NeuroImage.

Integrated Software Environment Based on COMKAT for Analyzing Tracer Pharmacokinetics with Molecular Imaging

Hsuan-Ming Huang, Cristian Salinas, Yu-Hua Dean Fang, 2010, Journal of Nuclear Medicine.

Biodistribution and Radiation Dosimetry of the Serotonin 5-HT6 Ligand [11C]GSK215083 Determined from Human Whole-Body PET

Alan A. Wilson, S. Houle, N. Keat, 2012, Molecular Imaging and Biology.

First-in-human PET imaging of mGluR2 receptors.

Talakad G. Lohith, G. Bormans, E. Hostetler, 2016 .

EARLY CLINICAL RESULTS AND PRECLINICAL VALIDATION OF THE O-GLCNACASE (OGA) INHIBITOR MK-8719 AS A NOVEL THERAPEUTIC FOR THE TREATMENT OF TAUOPATHIES

Dawn M. Toolan, Joseph James Duffy, J. Renger, 2016, Alzheimer's & Dementia.

Monoamine Transporter Occupancy of a Novel Triple Reuptake Inhibitor in Baboons and Humans Using Positron Emission Tomography

M. Laruelle, E. Rabiner, R. Gunn, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Prediction of Repeat-Dose Occupancy from Single-Dose Data: Characterisation of the Relationship between Plasma Pharmacokinetics and Brain Target Occupancy

M. Laruelle, G. Searle, E. Rabiner, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.