T. Tran

发表

Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor

I. McLay, Shawn P. Williams, I. Uings, 2009, Proceedings of the National Academy of Sciences.

Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo

Bryan L. Roth, Xi-Ping Huang, B. Roth, 2009, Psychopharmacology.

N-Alkyl-octahydroisoquinolin-1-one-8-carboxamides: a Novel Class of Selective, Nonbasic, Nitrogen-Containing κ-Opioid Receptor Ligands.

V. Setola, B. Roth, P. Ghosh, 2010, ACS medicinal chemistry letters.

N-Alkyl-octahydroisoquinolin-1-one-8-carboxamides: Selective and Nonbasic κ-Opioid Receptor Ligands

V. Setola, B. Roth, P. Ghosh, 2010 .

Sequential Metabolism of AMG 487, a Novel CXCR3 Antagonist, Results in Formation of Quinone Reactive Metabolites That Covalently Modify CYP3A4 Cys239 and Cause Time-Dependent Inhibition of the Enzyme

D. Rock, R. Subramanian, G. Tonn, 2012, Drug Metabolism and Disposition.

Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors.

K. Scearce-Levie, A. Beresford, A. Medhurst, 2012, Journal of medicinal chemistry.

Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quino

J. McCarter, D. Whittington, Iain D. G. Campuzano, 2016, Journal of medicinal chemistry.

Synthesis and SAR study of potent and selective PI3Kδ inhibitors.

J. McCarter, D. Metz, S. Wong, 2015, Bioorganic & medicinal chemistry letters.

Visible-Light-Driven Photocatalytic Degradation of Rhodamine B over Bimetallic Cu/Ti-MOFs

T. Tran, S. Do, Hong-Tham T. Nguyen, 2022, Indonesian Journal of Chemistry.

2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

C. Duraiswami, Yonghui Wang, T. Graybill, 2009, Bioorganic & medicinal chemistry letters.

Predicting new molecular targets for known drugs

Michael J. Keiser, J. Irwin, B. Shoichet, 2009, Nature.

Homoleptic group 12 metal bis(mercaptoimidazolyl)borate complexes M(Bm(R))2 (M = Zn, Cd, Hg).

T. Tran, D. Rabinovich, H. Alvarez, 2003, Inorganic chemistry.

Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors.

J. McCarter, D. Whittington, D. Metz, 2016, Journal of medicinal chemistry.

Discovery of selective LRRK2 inhibitors guided by computational analysis and molecular modeling.

Jason Drummond, Xingrong Liu, Yichin Liu, 2012, Journal of medicinal chemistry.

Synthesis of Mn-Doped Fe-MOFs with Different Ratios and Its Application for Photocatalytic Degradation of Rhodamine B Dye

T. Tran, S. Do, Kim-Ngan T. Tran, 2022, Indonesian Journal of Chemistry.

The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist.

Shawn P. Williams, S. Short, T. Consler, 2009, Acta crystallographica. Section D, Biological crystallography.

Strain-Dependent Variability of Early Discovery Small Molecule Pharmacokinetics in Mice: Does Strain Matter?

Brooke M. Rock, J. T. Barr, T. Tran, 2020, Drug Metabolism and Disposition.

Fraction Unbound for Liver Microsome and Hepatocyte Incubations for All Major Species Can Be Approximated Using a Single-Species Surrogate

Julie M. Lade, J. T. Barr, T. Tran, 2019, Drug Metabolism And Disposition.

Predicting new molecular targets for known drugs

Michael J. Keiser, J. Irwin, B. Shoichet, 2009, Nature.

Characterization of Nefazodone Time‐dependent Inhibition of Cytochrome P450 3A

D. Rock, Brooke M. Rock, T. Tran, 2017, The FASEB Journal.