K. Hashimoto

发表

Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury.

G. Korbutt, B. Thébaud, S. Bonnet, 2005, American journal of respiratory and critical care medicine.

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Sébastien Bonnet, S. Archer, J. Allalunis-Turner, 2007, Cancer cell.

In Vivo Gene Transfer of the O2-Sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic Rats

J. Dyck, S. Archer, B. Thébaud, 2003, Circulation.

Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic-Sensitive Potassium Channel Kv 1 . 5 Reduces Pulmonary 2 In Vivo Gene

J. Dyck, S. Archer, B. Thébaud, 2003 .

The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted

S. Archer, S. Bonnet, E. Michelakis, 2007, Proceedings of the National Academy of Sciences.

Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.

S. Archer, M. S. Mcmurtry, E. Michelakis, 2007, American journal of physiology. Lung cellular and molecular physiology.

Calvarial Bone Implantation and in vivo Imaging of Tumor Cells in Mice.

S. Takeda, H. Ochi, Shingo Sato, 2019, Bio-protocol.

Endothelium-Derived Hyperpolarizing Factor in Human Internal Mammary Artery Is 11,12-Epoxyeicosatrienoic Acid and Causes Relaxation by Activating Smooth Muscle BKCa Channels

S. Archer, J. Falck, J. Falck, 2003, Circulation.

METHOD FOR TREATING CANCER CROSS REFERENCE TO RELATED APPLICATION

C. Porter, K. Hashimoto, Christopher T. Lee, 2017 .

Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension Comparison With Inhaled Nitric Oxide

S. Archer, E. Michelakis, K. Hashimoto, 2002 .

Potassium channels regulate tone in rat pulmonary veins.

S. Archer, E. K. Weir, E. Michelakis, 2001, American journal of physiology. Lung cellular and molecular physiology.

Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.

J. Dyck, S. Archer, M. S. Mcmurtry, 2001, Advances in experimental medicine and biology.

The neurovascular mechanism of clitoral erection: nitric oxide and cGMP‐stimulated activation of BKCa channels

S. Archer, E. Michelakis, K. Hashimoto, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Sildenafil Reverses O2 Constriction of the Rabbit Ductus Arteriosus by Inhibiting Type 5 Phosphodiesterase and Activating BKCa Channels

S. Archer, B. Thébaud, E. Michelakis, 2002, Pediatric Research.

Dichloroacetate Prevents and Reverses Pulmonary Hypertension by Inducing Pulmonary Artery Smooth Muscle Cell Apoptosis

J. Dyck, M. S. Mcmurtry, S. Bonnet, 2004, Circulation research.

dysfunction and dysplasia in rats Chronic hypoxia induces nonreversible right ventricle

V. Eder, G. Korbutt, B. Thébaud, 2006 .

Oxygen Activates the Rho/Rho-Kinase Pathway and Induces RhoB and ROCK-1 Expression in Human and Rabbit Ductus Arteriosus by Increasing Mitochondria-Derived Reactive Oxygen Species: A Newly Recognized Mechanism for Sustaining Ductal Constriction

S. Archer, Hidemi Kajimoto, B. Thébaud, 2007, Circulation.

Oxygen-Sensitive Kv Channel Gene Transfer Confers Oxygen Responsiveness to Preterm Rabbit and Remodeled Human Ductus Arteriosus: Implications for Infants With Patent Ductus Arteriosus

J. Dyck, S. Archer, B. Thébaud, 2004, Circulation.

Extrusion of mitochondrial contents from lipopolysaccharide-stimulated cells: Involvement of autophagy

K. Hashimoto, K. Uemura, T. Aki, 2015, Autophagy.

Preferential Expression and Function of Voltage-Gated, O2-Sensitive K+ Channels in Resistance Pulmonary Arteries Explains Regional Heterogeneity in Hypoxic Pulmonary Vasoconstriction: Ionic Diversity in Smooth Muscle Cells

S. Archer, B. Thébaud, M. S. Mcmurtry, 2004, Circulation research.

Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage‐gated potassium channel Kv1.5

S. Archer, E. Michelakis, B. London, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Vascular Endothelial Growth Factor Gene Therapy Increases Survival, Promotes Lung Angiogenesis, and Prevents Alveolar Damage in Hyperoxia-Induced Lung Injury: Evidence That Angiogenesis Participates in Alveolarization

S. Archer, G. Thurston, G. Korbutt, 2005, Circulation.

O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide

S. Archer, B. Thébaud, E. Michelakis, 2004, Biological chemistry.

In Vitro and In Vivo Antifungal Activities of T-2307, a Novel Arylamidine

A. Kimura, H. Narita, K. Hashimoto, 2008, Antimicrobial Agents and Chemotherapy.

Developmental Absence of the O2 Sensitivity of L-Type Calcium Channels in Preterm Ductus Arteriosus Smooth Muscle Cells Impairs O2 Constriction Contributing to Patent Ductus Arteriosus

S. Archer, Hidemi Kajimoto, B. Thébaud, 2008, Pediatric Research.

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

E. Michelakis, P. Dromparis, K. Hashimoto, 2014, Cell.

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A

N. Kosaka, T. Ochiya, S. Takeda, 2018, Proceedings of the National Academy of Sciences.

Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.

S. Archer, G. Korbutt, B. Thébaud, 2009, American journal of respiratory and critical care medicine.

Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension: Comparison With Inhaled Nitric Oxide

E. Michelakis, K. Hashimoto, W. Tymchak, 2002, Circulation.

Soluble RANKL is physiologically dispensable but accelerates tumour metastasis to bone

H. Takayanagi, T. Okamura, K. Hashimoto, 2019, Nature metabolism.

Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition.

S. Archer, E. Michelakis, K. Hashimoto, 2002, American journal of physiology. Heart and circulatory physiology.

O2 Sensing in the Human Ductus Arteriosus: Regulation of Voltage-Gated K+ Channels in Smooth Muscle Cells by a Mitochondrial Redox Sensor

Bernard Thébaud, J. Dyck, S. Archer, 2002, Circulation research.

Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing

S. Takeda, H. Ochi, Shingo Sato, 2019, International journal of molecular sciences.

Soluble RANKL is physiologically dispensable but accelerates tumour metastasis to bone

H. Takayanagi, T. Okamura, K. Hashimoto, 2019, Nature Metabolism.

A Nuclear Pyruvate Dehydrogenase Complex Is Important for the Generation of Acetyl-CoA and Histone Acetylation

E. Michelakis, P. Dromparis, K. Hashimoto, 2014, Cell.

In Vitro and In Vivo Antifungal Activities of T-2307, a Novel Arylamidine

A. Kimura, H. Narita, K. Hashimoto, 2008, Antimicrobial Agents and Chemotherapy.