S. Aggarwal

发表

Exposure of neonatal mice to bromine impairs their alveolar development and lung function.

S. Matalon, N. Ambalavanan, T. Jilling, 2018, American journal of physiology. Lung cellular and molecular physiology.

RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury

Haiyang Tang, S. Black, Ting Wang, 2020, Redox Biology.

Role of apoptosis and autophagy in tuberculosis.

L. A. Riesenberg, S. Aggarwal, Christine M Gross, 2017, American journal of physiology. Lung cellular and molecular physiology.

Sox18 Preserves the Pulmonary Endothelial Barrier Under Conditions of Increased Shear Stress

A. Verin, S. Black, S. Aggarwal, 2014, Journal of cellular physiology.

Hyper‐activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury

J. Catravas, J. Garcia, M. Cherian‐Shaw, 2017, Free radical biology & medicine.

Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.

J. Catravas, A. Verin, S. Black, 2014, American journal of respiratory cell and molecular biology.

Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection

S. Matalon, Z. Bebők, A. Lazrak, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: a legitimate approach.

R. Hartmann, T. Bhardwaj, Suresh Thareja, 2012, European journal of medicinal chemistry.

oxide: role of cyclic AMP GTP cyclohydrolase I expression is regulated by nitric

S. Black, Shruti Sharma, Kandasamy Ravi, 2016 .

Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonary hypertension.

R. Rafikov, S. Black, D. Jonigk, 2013, Free radical biology & medicine.

GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP.

S. Black, Shruti Sharma, Kandasamy Ravi, 2009, American journal of physiology. Lung cellular and molecular physiology.

Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension.

R. Rafikov, J. Yuan, S. Black, 2016, Free radical biology & medicine.

Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.

J. Catravas, A. Verin, S. Black, 2009, Physiological genomics.

A STUDY TO COMPARE THE CLINICAL FEATURES BETWEEN POST PULMONARY TUBERCULOSIS ASSOCIATED CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) WITH OTHER COPD PATIENTS

Ashutosh Kumar Singh, S. Verma, S. Kant, 2017 .

Oxidative stress and the development of endothelial dysfunction in congenital heart disease with increased pulmonary blood flow: lessons from the neonatal lamb.

S. Black, S. Aggarwal, J. Fineman, 2010, Trends in cardiovascular medicine.

Asymmetric Dimethylarginine Induces Endothelial Nitric-oxide Synthase Mitochondrial Redistribution through the Nitration-mediated Activation of Akt1*

R. Rafikov, S. Black, D. Fulton, 2012, The Journal of Biological Chemistry.

Reactive oxygen species in pulmonary vascular remodeling.

S. Black, Shruti Sharma, S. Aggarwal, 2013, Comprehensive Physiology.

Yet to Come Reactive Oxygen Species in Pulmonary Vascular Remodeling Comprehensive Physiology Inflammation Shear stress Hypoxia Contractile phenotypic markers Proliferative phenotypic markers Altered Ca 2 + homeostasis Vascular SMC SMC contraction and proliferation Growth factors Pulmonary vascular

S. Black, Shruti Sharma, S. Aggarwal, 2013 .

Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation.

S. Matalon, S. Komarova, Jianhua Zhang, 2015, Free radical biology & medicine.

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G+ -Toxins

J. Catravas, A. Verin, S. Black, 2014, PloS one.

Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.

R. Rafikov, S. Black, S. Fratz, 2013, Antioxidants & redox signaling.

Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema.

S. Matalon, J. Wells, M. Dransfield, 2018, JCI insight.

Hyper-Activation of pp 60 ( Src ) Limits Nitric Oxide Signaling by Increasing Asymmetric Dimethylarginine Levels During Acute Lung Injury

Wang, Ting, J. Catravas, 2018 .

Mechanisms of nitric oxide synthase uncoupling in endotoxin-induced acute lung injury: role of asymmetric dimethylarginine.

J. Catravas, S. Black, D. Fulton, 2010, Vascular pharmacology.

Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167.

R. Rafikov, Yali Hou, S. Black, 2014, Free radical biology & medicine.

Purification and functional analysis of protein kinase G-1α using a bacterial expression system.

R. Rafikov, S. Black, S. Aggarwal, 2011, Protein expression and purification.

Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors.

R. Hartmann, Rajnish Kumar, T. Bhardwaj, 2016, Bioorganic & medicinal chemistry.

Phosgene Inhalation Causes Hemolysis and Acute Lung Injury

S. Matalon, D. Ford, T. Jilling, 2019, bioRxiv.

Phosgene inhalation causes hemolysis and acute lung injury.

S. Matalon, D. Ford, T. Jilling, 2019, Toxicology letters.

Assessment of biological half life using in silico QSPkR approach: a self organizing molecular field analysis (SOMFA) on a series of antimicrobial quinolone drugs.

M. Kumar, V. Sinha, Suresh Thareja, 2011, International journal of pharmaceutics.

Hyaluronan and halogen‐induced airway hyperresponsiveness and lung injury

S. Matalon, T. Jilling, A. Lazrak, 2020, Annals of the New York Academy of Sciences.

Lipopolysaccharide-induced Lung Injury Involves the Nitration-mediated Activation of RhoA*

J. Catravas, A. Verin, R. Rafikov, 2014, The Journal of Biological Chemistry.

Protein engineering to develop a redox insensitive endothelial nitric oxide synthase☆

R. Rafikov, S. Black, M. Springer, 2014, Redox biology.

Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites.

T. Kole, S. Denmeade, R. Cotter, 2008, Biochemistry.

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.

J. Catravas, A. Verin, S. Black, 2010, Vascular pharmacology.

NF-κB-dependent repression of Sox18 transcription factor requires the epigenetic regulators histone deacetylases 1 and 2 in acute lung injury

S. Black, S. Aggarwal, Christine M Gross, 2022, Frontiers in Physiology.

Heme attenuates beta-endorphin levels in leukocytes of HIV positive individuals with chronic widespread pain

S. Matalon, S. Aggarwal, B. Goodin, 2020, Redox biology.

Heme Attenuates Endogenous Opioid Levels in Leukocytes of HIV positive individuals with Chronic Widespread Pain

S. Matalon, S. Aggarwal, B. Goodin, 2020, bioRxiv.

Neuroprotective Effect of Cyclooxygenase Inhibitors in ICV-STZ Induced Sporadic Alzheimer’s Disease in Rats

S. V. Padi, D. Dhull, S. Aggarwal, 2011, Journal of Molecular Neuroscience.

NipR 1 Peptide Binding to RhoA — To assess peptide binding to RhoA , we utilized biotinylated

J. Catravas, A. Verin, R. Rafikov, 2014 .

Glutathione Supplementation Attenuates Lipopolysaccharide-Induced Mitochondrial Dysfunction and Apoptosis in a Mouse Model of Acute Lung Injury

S. Black, Shruti Sharma, S. Aggarwal, 2012, Front. Physio..

Vascular Endothelial Growth Factor‐121 Administration Mitigates Halogen Inhalation‐Induced Pulmonary Injury and Fetal Growth Restriction in Pregnant Mice

S. Matalon, T. Jilling, C. Ren, 2020, Journal of the American Heart Association.

Increased NADPH oxidase-derived superoxide is involved in the neuronal cell death induced by hypoxia-ischemia in neonatal hippocampal slice cultures.

Thomas F. Rau, D. Poulsen, Yali Hou, 2012, Free radical biology & medicine.

Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury

Haiyang Tang, S. Black, Ting Wang, 2021, The Journal of biological chemistry.

Can a Vitamin a Day Keep Tuberculosis Away?

S. Aggarwal, J. DeBerry, 2018, American journal of respiratory cell and molecular biology.

CALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury

S. Matalon, S. Komarova, A. Lazrak, 2015 .

Mechanisms and Treatment of Halogen Inhalation–Induced Pulmonary and Systemic Injuries in Pregnant Mice

S. Matalon, N. Ambalavanan, D. Ford, 2017, Hypertension.

Tezosentan increases nitric oxide signaling via enhanced hydrogen peroxide generation in lambs with surgically induced acute increases in pulmonary blood flow

R. Rafikov, Yali Hou, S. Black, 2013, Journal of cellular biochemistry.

A dimeric peptide that binds selectively to prostate-specific membrane antigen and inhibits its enzymatic activity.

J. Isaacs, S. Denmeade, S. Aggarwal, 2006, Cancer research.

Rosiglitazone preserves pulmonary vascular function in lambs with increased pulmonary blood flow

S. Black, S. Fratz, A. Azakie, 2012, Pediatric Research.

Role of heme in bromine‐induced lung injury

S. Matalon, S. Aggarwal, Adam Lam, 2016, Annals of the New York Academy of Sciences.

Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury.

S. Matalon, A. Agarwal, A. Traylor, 2016, Antioxidants & redox signaling.

Comparative study of PSMA expression in the prostate of mouse, dog, monkey, and human

Simon A. Williams, S. Denmeade, S. Aggarwal, 2006, The Prostate.

SYNTHESIS, PHARMACOLOGICAL AND TOXICOLOGICAL EVALUATION OF AMIDE DERIVATIVES OF IBUPROFEN

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2003 .

An overview on 5α-reductase inhibitors

Saurabh Aggarwal, Abhilasha Verma, T. Bhardwaj, 2010, Steroids.

An overview of phytotherapeutic approaches for the treatment of benign prostatic hyperplasia.

Sonali Batra, T. Bhardwaj, S. Aggarwal, 2014, Mini reviews in medicinal chemistry.

Synthesis and In Vitro Evaluation of Novel 1, 2, 4-Triazole Derivatives as Antifungal Agents

Suresh Thareja, S. Aggarwal, G. Kokil, 2010 .

Oxidative Stress and Pulmonary Vascular Disorders

R. Rafikov, S. Black, S. Aggarwal, 2014 .

Differential regulation of autophagy and mitophagy in pulmonary diseases.

Jianhua Zhang, P. Mannam, S. Aggarwal, 2016, American journal of physiology. Lung cellular and molecular physiology.

LPS‐induced Acute Lung Injury Involves NF‐&kgr;B‐mediated Downregulation of SOX18

M. Gonzalez-Garay, J. Catravas, A. Verin, 2017, American journal of respiratory cell and molecular biology.

A combinatorial approach to the selective capture of circulating malignant epithelial cells by peptide ligands.

Saurabh Aggarwal, J. Harden, S. Denmeade, 2005, Biomaterials.

Protein Tyrosine Phosphatase 1B Inhibitors: A Molecular Level Legitimate Approach for the Management of Diabetes Mellitus

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2012, Medicinal research reviews.

LPS decreases CFTR open probability and mucociliary transport through generation of reactive oxygen species

S. Matalon, Z. Bebők, S. Rowe, 2021, Redox biology.

Chapter 14 – Pulmonary Hemodynamics

S. Black, S. Aggarwal, Christine M Gross, 2015 .

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

S. Denmeade, S. Aggarwal, W. Brennen, 2009, Molecular Cancer Therapeutics.

Halogen-Induced Chemical Injury to the Mammalian Cardiopulmonary Systems.

S. Matalon, T. Jilling, A. Lazrak, 2021, Physiology.

Chlorine‐induced cardiopulmonary injury

S. Matalon, E. Svendsen, S. Aggarwal, 2016, Annals of the New York Academy of Sciences.

Chlorine inhalation induces acute chest syndrome in humanized sickle cell mouse model and ameliorated by postexposure hemopexin

S. Matalon, N. Ambalavanan, D. Ford, 2021, Redox biology.

Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndrome

S. Matalon, D. Ford, A. Lazrak, 2020, Redox biology.

Heme Impairs Alveolar Epithelial Sodium Channels Post Toxic Gas Inhalation

S. Matalon, D. Ford, A. Lazrak, 2020 .

Synthesis and screening of a random dimeric peptide library using the one-bead-one-dimer combinatorial approach.

J. Harden, S. Denmeade, S. Aggarwal, 2006, Bioconjugate chemistry.

Endothelial Nitric Oxide Synthase Deficient Mice Are Protected from Lipopolysaccharide Induced Acute Lung Injury

R. Rafikov, S. Black, R. Lucas, 2015, PloS one.

Neuroprotective Effect of Cyclooxygenase Inhibitors in ICV-STZ Induced Sporadic Alzheimer’s Disease in Rats

S. V. Padi, D. Dhull, S. Aggarwal, 2011, Journal of Molecular Neuroscience.

Chronic inhibition of PPAR-γ signaling induces endothelial dysfunction in the juvenile lamb.

R. Rafikov, S. Black, Shruti Sharma, 2013, Pulmonary pharmacology & therapeutics.

Nitration of Tyrosine 247 Inhibits Protein Kinase G-1α Activity by Attenuating Cyclic Guanosine Monophosphate Binding*

R. Rafikov, S. Black, D. Jonigk, 2014, The Journal of Biological Chemistry.

Chronic Pain in HIV

S. Aggarwal, Dylan R. Addis, J. DeBerry, 2020, Molecular pain.

Attenuated vasodilatation in lambs with endogenous and exogenous activation of cGMP signaling: Role of protein kinase G nitration

S. Black, S. Fratz, S. Aggarwal, 2011, Journal of cellular physiology.

Endothelin-1 induces a glycolytic switch in pulmonary arterial endothelial cells via the mitochondrial translocation of endothelial nitric oxide synthase.

Yunchao Su, Yali Hou, S. Black, 2014, American journal of respiratory cell and molecular biology.

Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier.

S. Matalon, J. Pittet, S. Garantziotis, 2018, American journal of physiology. Lung cellular and molecular physiology.

Self-organizing molecular field analysis on pregnane derivatives as human steroidal 5α-reductase inhibitors

M. Kumar, T. Bhardwaj, Suresh Thareja, 2010, Steroids.

AICAR decreases acute lung injury by phosphorylating AMPK and upregulating heme oxygenase-1

S. Matalon, Gang Liu, T. Jilling, 2021, European Respiratory Journal.

Self-organizing molecular field analysis of 2,4-thiazolidinediones: A 3D-QSAR model for the development of human PTP1B inhibitors.

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2010, European journal of medicinal chemistry.

Sulphonamides as inhibitors of protein tyrosine phosphatase 1B: a three-dimensional quantitative structure-activity relationship study using self-organizing molecular field analysis approach.

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2010, Chemical & pharmaceutical bulletin.

3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: a self organizing molecular field analysis approach.

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2010, European journal of medicinal chemistry.

Self organizing molecular field analysis on a series of human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroid.

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2009, European journal of medicinal chemistry.

Targeted cancer therapies

S. Aggarwal, 2010, Nature Reviews Drug Discovery.

High Heme and Low Heme Oxygenase-1 Are Associated with Mast Cell Activation/Degranulation in HIV-Induced Chronic Widespread Pain

J. X. Masjoan Juncos, S. Aggarwal, B. Goodin, 2023, Antioxidants.

Heme-Induced Macrophage Phenotype Switching and Impaired Endogenous Opioid Homeostasis Correlate with Chronic Widespread Pain in HIV

J. X. Masjoan Juncos, S. Aggarwal, B. Goodin, 2023, Cells.

Self-Organizing Molecular Field Analysis on Pyridazine Analogues as Protein Tyrosine Phosphatase 1B (PTP 1B) Inhibitors

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2010 .

Targeted cancer therapies.

S. Aggarwal, 2010, Nature reviews. Drug discovery.

Saxagliptin: a new drug for the treatment of type 2 diabetes.

T. Bhardwaj, Suresh Thareja, S. Aggarwal, 2010, Mini-Reviews in Medical Chemistry.

Sex-Based Disparities in Leukocyte Migration and Activation in Response to Inhalation Lung Injury: Role of SDF-1/CXCR4 Signaling

J. X. Masjoan Juncos, S. Aggarwal, T. Lewis, 2023, Cells.

Vascular Permeability Disruption Explored in the Proteomes of Mouse Lungs and Human Microvascular Cells following Acute Bromine Exposure.

S. Matalon, D. Ford, J. Mobley, 2020, American journal of physiology. Lung cellular and molecular physiology.

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

A. LeBeau, S. Denmeade, S. Aggarwal, 2009, Molecular Cancer Therapeutics.

Increased NADPH oxidase-derived superoxide is involved in the neuronal cell death induced by hypoxia-ischemia in neonatal hippocampal slice cultures.

Thomas F. Rau, D. Poulsen, Yali Hou, 2012, Free radical biology & medicine.

Effect of PPARgamma inhibition on pulmonary endothelial cell gene expression: gene profiling in pulmonary hypertension.

J. Catravas, A. Verin, S. Black, 2009, Physiological genomics.

Attenuated vasodilatation in lambs with endogenous and exogenous activation of cGMP signaling: Role of protein kinase G nitration

S. Black, S. Fratz, S. Aggarwal, 2011, Journal of cellular physiology.

Chlorine‐induced cardiopulmonary injury

S. Matalon, E. Svendsen, S. Aggarwal, 2016, Annals of the New York Academy of Sciences.

Upregulation of Autophagy Decreases Chlorine Gas Induced Mitochondrial Injury and Lung Inflammation

S. Matalon, S. Komarova, Jianhua Zhang, 2015 .

Horsetail ferredoxin: isolation and some chemical studies.

H. Matsubara, K. K. Rao, S. Aggarwal, 1971, Journal of biochemistry.