S. Land

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Regulation of vascular signalling by nuclear Sprouty2 in fetal lung epithelial cells: Implications for co-ordinated airway and vascular branching in lung development

David J. Walker, D. Walker, S. Land, 2018, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

mTOR signalling, embryogenesis and the control of lung development.

S. Land, C. Scott, David Walker, 2014, Seminars in cell & developmental biology.

Control of HIF-1α and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock

A. Tee, E. Cwiklinski, D. Walker, 2010, American Journal of Physiology - Lung cellular and Molecular Physiology.

Redox regulation of lung development and perinatal lung epithelial function.

S. Land, Stuart M. Wilson, S. Wilson, 2005, Antioxidants & redox signaling.

Hypoxia-inducible Factor 1α Is Regulated by the Mammalian Target of Rapamycin (mTOR) via an mTOR Signaling Motif*

A. Tee, S. Land, Andrew R. Tee, 2007, Journal of Biological Chemistry.

Determining the pathogenicity of patient-derived TSC2 mutations by functional characterization and clinical evidence

S. McKee, H. Kingston, A. Tee, 2011, European Journal of Human Genetics.

Endotoxin-induced nitric oxide production rescues airway growth and maturation in atrophic fetal rat lung explants.

S. Land, C. Rae, C. Rae, 2006, Biochemical and biophysical research communications.

O2-evoked regulation of HIF-1α and NF-κB in perinatal lung epithelium requires glutathione biosynthesis

J. Haddad, S. Land, 2000 .

A non‐hypoxic, ROS‐sensitive pathway mediates TNF‐α‐dependent regulation of HIF‐1α

J. Haddad, S. Land, J. Haddad, 2001 .

The ex vivo differential expression of apoptosis signaling cofactors in the developing perinatal lung: essential role of oxygenation during the transition from placental to pulmonary-based respiration.

J. Haddad, S. Land, K. K. Choudhary, 2001, Biochemical and biophysical research communications.

A non-hypoxic, ROS-sensitive pathway mediates TNF-alpha-dependent regulation of HIF-1alpha.

J. Haddad, S. Land, 2001, FEBS letters.

Oxygen‐evoked Na+ transport in rat fetal distal lung epithelial cells

A. Collett, D. Baines, J. Haddad, 2001, The Journal of physiology.

Immunopharmacological potential of selective phosphodiesterase inhibition. I. Differential regulation of lipopolysaccharide-mediated proinflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) biosynthesis in alveolar epithelial cells.

J. Haddad, M. Zembala, W. Tarnow-Mordi, 2002, The Journal of pharmacology and experimental therapeutics.

Immunomodulatory potential of thymulin-Zn(2+) in the alveolar epithelium: amelioration of endotoxin-induced cytokine release and partial amplification of a cytoprotective IL-10-sensitive pathway.

J. Haddad, N. Saadé, S. Land, 2000, Biochemical and biophysical research communications.

Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells.

J. Haddad, S. Land, 2002, Antioxidants & redox signaling.

Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-kappaB/nuclear factor-kappaB-sensitive pathway in alveolar epithelial cells.

J. Haddad, M. Zembala, W. Tarnow-Mordi, 2002, The Journal of pharmacology and experimental therapeutics.

NF-kappaB blockade reduces the O2-evoked rise in Na+ conductance in fetal alveolar cells.

A. Collett, J. Haddad, S. Wilson, 2001, Biochemical and biophysical research communications.

Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium.

J. Haddad, N. Saadé, S. Land, 2001, The Journal of pharmacology and experimental therapeutics.

Amiloride Blockades Lipopolysaccharide-Induced Proinflammatory Cytokine Biosynthesis in an I κ B- α /NF- κ B–Dependent Mechanism: Evidence for the Amplification of an Antiinflammatory Pathway in the Alveolar Epithelium

J. Haddad, S. Land, 2002 .

The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting.

J. Haddad, S. Land, 2000, Biochemical and biophysical research communications.

Nuclear Factor-κB Blockade Attenuates but Does Not Abrogate Lipopolysaccharide-Dependent Tumor Necrosis Factor-α Biosynthesis in Alveolar Epithelial Cells

J. Haddad, S. Land, 2001 .

University of Dundee Dexamethasone and insulin activate serum and glucocorticoid-inducible kinase 1 ( SGK 1 ) via different molecular mechanisms in cortical collecting duct cells

David J. Walker, M. Bailey, D. Walker, 2016 .

Response of protein synthesis to anoxia and recovery in anoxia-tolerant hepatocytes.

P. W. Hochachka, L. Buck, S. Land, 1993, The American journal of physiology.

Anoxia-tolerant hepatocytes: model system for study of reversible metabolic suppression.

P. W. Hochachka, L. Buck, S. Land, 1993, The American journal of physiology.

Immunopharmacological Potential of Selective Phosphodiesterase Inhibition. II. Evidence for the Involvement of an Inhibitory- (cid:1) B/Nuclear Factor- (cid:1) B-Sensitive Pathway in Alveolar Epithelial Cells

J. Haddad, M. Zembala, W. Tarnow-Mordi, 2002 .

Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance

A. Mehta, S. Land, K. Tosoni, 2016, PloS one.

Chemioxyexcitation (delta pO2/ROS)-dependent release of IL-1 beta, IL-6 and TNF-alpha: evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium.

J. Haddad, N. Saadé, S. Land, 2001, Cytokine.

A regulated apical Na(+) conductance in dexamethasone-treated H441 airway epithelial cells.

S. Wilson, S. Land, K. Richard, 2004, American journal of physiology. Lung cellular and molecular physiology.

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

P. W. Hochachka, L. Buck, S. Land, 1996, Proceedings of the National Academy of Sciences of the United States of America.

A heme-protein-based oxygen-sensing mechanism controls the expression and suppression of multiple proteins in anoxia-tolerant turtle hepatocytes.

P. W. Hochachka, S. Land, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of vascular signalling by nuclear Sprouty2 in fetal lung epithelial cells: Implications for co-ordinated airway and vascular branching in lung development

David J. Walker, D. Walker, S. Land, 2018, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

The self-referencing oxygen-selective microelectrode: detection of transmembrane oxygen flux from single cells.

D M Porterfield, P. Smith, S. Land, 1999, The Journal of experimental biology.

Chapter 18 Estivation: Mechanisms and control of metabolic suppression

S. Land, N. Bernier, 1995 .

Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1α and NF-κB Redox Sensitivity

J. Haddad, S. Land, R. Olver, 2000, The Journal of Biological Chemistry.

Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation: evidence for involvement of an interleukin-1beta193-195 receptor antagonism in the alveolar epithelium.

J. Haddad, N. Saadé, S. Land, 2001 .

University of Dundee Vascular Growth in the Fetal Lung Land , Stephen

S. Land, 2017 .

Vascular Growth in the Fetal Lung

S. Land, 2011 .

COMPARTMENTATION OF LIVER PHOSPHOENOLPYRUVATE CARBOXYKINASE IN THE AQUATIC TURTLE PSEUDEMYS SCRIPTA ELEGANS: A REASSESSMENT

P. W. Hochachka, S. Land, 1993 .

Detection of Cl- flux in the apical microenvironment of cultured foetal distal lung epithelial cells.

A. Collett, S. Land, 2001, The Journal of experimental biology.

Amiloride blockades lipopolysaccharide-induced proinflammatory cytokine biosynthesis in an IkappaB-alpha/NF-kappaB-dependent mechanism. Evidence for the amplification of an antiinflammatory pathway in the alveolar epithelium.

J. Haddad, S. Land, 2002, American journal of respiratory cell and molecular biology.

Absence of the Birt–Hogg–Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

A. Pause, A. Tee, D. M. Davies, 2011, Oncogene.

Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonists.

S. Land, 2012, International journal of physiology, pathophysiology and pharmacology.

CHEMIOXYEXCITATION (Δp O2/ROS)-DEPENDENT RELEASE OF IL-1β, IL-6 AND TNF-α: EVIDENCE OF CYTOKINES AS OXYGEN-SENSITIVE MEDIATORS IN THE ALVEOLAR EPITHELIUM

J. Haddad, N. Saadé, S. Land, 2001 .

Protein turnover during metabolic arrest in turtle hepatocytes: role and energy dependence of proteolysis.

P. W. Hochachka, S. Land, Peter W. Hochachka, 1994, The American journal of physiology.

iNOS initiates and sustains metabolic arrest in hypoxic lung adenocarcinoma cells: mechanism of cell survival in solid tumor core.

S. Land, C. Rae, 2005, American journal of physiology. Cell physiology.

J. Haddad, N. Saadé, S. Land, 2001 .

Redox/ROS regulation of lipopolysaccharide‐induced mitogen‐activated protein kinase (MAPK) activation and MAPK‐mediated TNF‐α biosynthesis

J. Haddad, S. Land, 2002, British journal of pharmacology.

Thymulin evokes IL-6-C/EBPβ regenerative repair and TNF-α silencing during endotoxin exposure in fetal lung explants

F. Darakhshan, S. Land, 2004 .

Leukocyte Inflammatory Mediators and Lung Physiology Thymulin evokes IL-6C / EBP regenerative repair and TNF-silencing during endotoxin exposure in fetal lung explants

F. Darakhshan, S. Land, 2004 .

O2 availability modulates transmembrane Ca2+ flux via second-messenger pathways in anoxia-tolerant hepatocytes.

P. Smith, S. Land, R. Sanger, 1997, Journal of applied physiology.

Hochachka's "Hypoxia Defense Strategies" and the development of the pathway for oxygen.

S. Land, 2004, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Oxygen-sensing pathways and the development of mammalian gas exchange

S. Land, 2003, Redox report : communications in free radical research.

Thymulin evokes IL-6-C/EBPbeta regenerative repair and TNF-alpha silencing during endotoxin exposure in fetal lung explants.

F. Darakhshan, S. Land, 2004, American journal of physiology. Lung cellular and molecular physiology.

Oxygen sensing and signal transduction in metabolic defense against hypoxia: lessons from vertebrate facultative anaerobes.

P. W. Hochachka, L. Buck, S. Land, 1997, Comparative biochemistry and physiology. Part A, Physiology.

Dexamethasone and insulin activate serum and glucocorticoid‐inducible kinase 1 (SGK1) via different molecular mechanisms in cortical collecting duct cells

David J. Walker, M. Bailey, D. Walker, 2016, Physiological reports.

O2 can raise fetal pneumocyte Na+ conductance without affecting ENaC mRNA abundance.

S. Land, K. Richard, R. Olver, 2003, Biochemical and biophysical research communications.

Hypoxic activation of an amiloride-sensitive cation conductance in alveolar epithelial cells.

S. Wilson, S. Land, S. Jovanović, 2001, Biochemical and biophysical research communications.

Birt-Hogg-Dube syndrome is a novel ciliopathy.

A. Tee, R. Giles, J. Broers, 2013, Human molecular genetics.

Cardioprotective SUR2A promotes stem cell properties of cardiomyocytes☆☆☆

David J. Walker, A. Jovanovic, D. Walker, 2013, International journal of cardiology.

Antioxidant/pro-oxidant equilibrium regulates HIF-1alpha and NF-kappa B redox sensitivity. Evidence for inhibition by glutathione oxidation in alveolar epithelial cells.

J. Haddad, S. Land, R. Olver, 2000, The Journal of biological chemistry.

3 Vascular Growth in the Fetal Lung

S. Land, 2022 .

The biphasic immunoregulation of pyrimidylpiperazine (Y‐40138) is IL‐10 sensitive and requires NF‐κB targeting in the alveolar epithelium

J. Haddad, N. Saadé, S. Land, 2001, British journal of pharmacology.

Expression of Wild-Type CFTR Suppresses NF-κB-Driven Inflammatory Signalling

A. Mehta, S. Land, K. Treharne, 2010, PloS one.

Control of HIF-1α and vascular signaling in fetal lung involves cross talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock

David J. Walker, A. Tee, E. Cwiklinski, 2010, American Journal of Physiology - Lung Cellular and Molecular Physiology.

Epithelial Na+ channel activity in human airway epithelial cells: the role of serum and glucocorticoid‐inducible kinase 1

S. Land, G. Watt, A. G. Caballero, 2012, British journal of pharmacology.

mTOR signalling, embryogenesis and the control of lung development.

S. Land, C. Scott, David Walker, 2014, Seminars in cell & developmental biology.