W. Shi

发表

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development

G. E. Fernandez, D. Warburton, R. Moats, 2018, Scientific Reports.

Loss of FLCN inhibits canonical WNT signaling via TFE3.

E. Henske, W. Shi, J. Kennedy, 2019, Human molecular genetics.

Transient overexpression of Gremlin results in epithelial activation and reversible fibrosis in rat lungs.

D. Warburton, L. Farkas, M. Kolb, 2011, American journal of respiratory cell and molecular biology.

Rho/ROCK-MYOCD in regulating airway smooth muscle growth and remodeling.

W. Shi, Qin Yang, 2021, American journal of physiology. Lung cellular and molecular physiology.

Pediatric Acute Respiratory Distress Syndrome: Fibrosis versus Repair

B. Driscoll, W. Shi, D. Im, 2016, Front. Pediatr..

VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis.

D. Warburton, S. Bellusci, E. Keshet, 2006, Developmental biology.

Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme

J. Wysolmerski, W. Shi, M. Hiremath, 2012, Development.

Is COPD in adulthood really so far removed from early development?

D. Warburton, W. Shi, 2010, European Respiratory Journal.

Isolation of purified and live Foxp3+ regulatory T cells using FACS sorting on scatter plot.

S. Zheng, H. Fan, Zhongmin Liu, 2010, Journal of molecular cell biology.

Isolation of Purified and Live Foxp3+ Regulatory T Cells Using FACS Sorting on Scatter Plot

S. Zheng, H. Fan, Zhongmin Liu, 2010 .

Molecular determinants of lung development.

J. Rossant, T. Mariani, J. Epstein, 2013, Annals of the American Thoracic Society.

Seventh BHD international symposium: recent scientific and clinical advancement

W. Linehan, R. Zoncu, E. Henske, 2022, Oncotarget.

Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome

R. Moats, E. Henske, Larry L. Wang, 2020, Thorax.

Lung development and adult lung diseases.

D. Warburton, S. Bellusci, W. Shi, 2007, Chest.

Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice.

S. Zheng, D. Warburton, Wei Xu, 2012, American journal of physiology. Lung cellular and molecular physiology.

Molecular mechanisms of MMP 9 overexpression and its role in emphysema pathogenesis of Smad 3-deficient mice

S. Zheng, D. Warburton, H. Chen, 2012 .

Xiao-Fan Wang emphysema deficiency is a developmental antecedent of centrilobular Abnormal mouse lung alveolarization caused by Smad 3

D. Warburton, Xiao-Fan Wang, S. Buckley, 2005 .

Cigarette Smoke-Induced Lung Endothelial and Alveolar Epithelial Injury Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad 3 knockout mice

D. Warburton, L. Farkas, N. Voelkel, 2011 .

Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice.

D. Warburton, L. Farkas, N. Voelkel, 2011, American journal of physiology. Lung cellular and molecular physiology.

Lung mesenchymal expression of Sox9 plays a critical role in tracheal development

D. Warburton, D. Menke, Gianluca Turcatel, 2013, BMC Biology.

BMP4 signaling induces senescence and modulates the oncogenic phenotype of A549 lung adenocarcinoma cells.

D. Warburton, B. Driscoll, S. Buckley, 2004, American journal of physiology. Lung cellular and molecular physiology.

Smad1 expression and function during mouse embryonic lung branching morphogenesis.

D. Warburton, H. Chen, Yuhua Chen, 2005, American journal of physiology. Lung cellular and molecular physiology.

Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins.

D. Warburton, Yan-Ling Wang, K. Anderson, 2004, American journal of physiology. Lung cellular and molecular physiology.

BMP 4 signaling induces senescence and modulates the oncogenic phenotype of A 549 lung adenocarcinoma cells

D. Warburton, B. Driscoll, S. Buckley, 2003 .

TACE is required for fetal murine cardiac development and modeling.

D. Warburton, S. Buckley, K. Anderson, 2003, Developmental biology.

Increased alveolar soluble annexin V promotes lung inflammation and fibrosis

D. Warburton, R. Moats, M. Selman, 2015, European Respiratory Journal.

New Developments in the Pathogenesis of Pulmonary Cysts in Birt–Hogg–Dubé Syndrome

E. Henske, W. Shi, J. Kennedy, 2020, Seminars in Respiratory and Critical Care Medicine.

Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis.

D. Warburton, S. Bellusci, W. Ding, 2004, American journal of physiology. Lung cellular and molecular physiology.

TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?

D. Warburton, W. Shi, Bing Xu, 2013, American journal of physiology. Lung cellular and molecular physiology.

Lo, and the niche is knit: lysyl oxidase activity and maintenance of lung, aorta, and skin integrity.

D. Warburton, W. Shi, 2005, The American journal of pathology.

Do lung remodeling, repair, and regeneration recapitulate respiratory ontogeny?

J. Thiery, D. Warburton, S. Bellusci, 2001, American journal of respiratory and critical care medicine.

Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation

D. Warburton, R. Moats, G. Pryhuber, 2019, Scientific Reports.

Smad1 and its target gene Wif1 coordinate BMP and Wnt signaling activities to regulate fetal lung development

Hui Chen, Min Xu, Wei Shi, 2011, Development.

BMP signaling is essential in neonatal surfactant production during respiratory adaptation.

Y. Mishina, Nan Li, Hui Chen, 2016, American journal of physiology. Lung cellular and molecular physiology.

, Nan Li , Yuji Mishina and Wei Shi production during respiratory adaptation BMP signaling is essential in neonatal surfactant

Y. Mishina, Nan Li, Hui Chen, 2016 .

Cell Signaling and Growth Factors in Lung Development

V. Kaartinen, D. Warburton, S. Bellusci, 2008 .

Lung development and susceptibility to chronic obstructive pulmonary disease.

D. Warburton, S. Bellusci, J. Gauldie, 2006, Proceedings of the American Thoracic Society.

Overexpression of Smurf 1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad 1 and Smad 5 proteins

D. Warburton, Yan-Ling Wang, K. Anderson, 2003 .

Overexpression of transforming growth factor-&bgr;1 in fetal monkey lung results in prenatal pulmonary fibrosis

D. Warburton, S. Buckley, M. Kolb, 2010, European Respiratory Journal.

Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme

D. Kotton, W. Shi, C. Villacorta-Martin, 2022, bioRxiv.

Inactivation of Tsc2 in Abcg2 Lineage Derived Cells Drives the Appearance of Polycystic Lesions and Fibrosis in the Adult Kidney.

K. Hopp, J. Harral, K. Ess, 2019, American journal of physiology. Renal physiology.

A cysteine residue in the helix-loop-helix domain of Id2 is critical for homodimerization and function.

D. Warburton, W. Shi, J. Liu, 2000, Biochemical and biophysical research communications.

Intrinsic BMP inhibitor Gremlin regulates lung alveolar progenitor cell proliferation and differentiation

M. Kolb, K. Tsubouchi, K. Ask, 2022, bioRxiv.

Gremlin promotes peritoneal membrane injury in an experimental mouse model and is associated with increased solute transport in peritoneal dialysis patients.

Limin Liu, A. Gangji, K. S. Brimble, 2014, The American journal of pathology.

A novel function for the protein tyrosine phosphatase Shp2 during lung branching morphogenesis.

D. Warburton, S. Bellusci, W. Shi, 2005, Developmental biology.

Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling

C. Ruppert, A. Günther, V. Vijayan, 2015, Proceedings of the National Academy of Sciences.

TACE in perinatal mouse lung epithelial cells promotes lung saccular formation.

Chengyu Liu, V. Kaartinen, Wei Xu, 2013, American journal of physiology. Lung cellular and molecular physiology.

The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors.

D. Warburton, B. Driscoll, S. Buckley, 2011, American journal of respiratory cell and molecular biology.

Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization.

D. Warburton, E. Henske, Larry L. Wang, 2016, The American journal of pathology.

Lysyl Oxidase‐Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor‐&bgr;1‐induced Pulmonary Fibrosis

Seidai Sato, C. Shimbori, M. Kolb, 2017, American journal of respiratory cell and molecular biology.

Optimising experimental research in respiratory diseases: an ERS statement

G. Joos, W. Kuebler, L. Richeldi, 2018, European Respiratory Journal.

On The Functional Dynamics of Alveolar and Ductal Growth in The Adolescent Lung

David S. Koos, D. Warburton, R. Moats, 2021 .

Molecular Mechanisms of Early Lung Specification and Branching Morphogenesis

D. Warburton, S. Bellusci, V. Fleury, 2005, Pediatric Research.

TGFβ signaling plays a critical role in promoting alternative macrophage activation

N. Heisterkamp, J. Groffen, S. Yi, 2012, BMC Immunology.

Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF‐β1 signaling and EGF as well as FGF receptor tyrosine kinase‐ERK pathways in mesenchymal cells

D. Warburton, N. Heisterkamp, J. Groffen, 2007, Journal of cellular physiology.

Synergistic effect of TGF‐β superfamily members on the induction of Foxp3+ Treg

S. Zheng, Xuehao Wang, W. Shi, 2009, European journal of immunology.

Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice.

D. Warburton, Xiao-Fan Wang, M. Datto, 2002, American journal of physiology. Lung cellular and molecular physiology.

Antigen-specific transforming growth factor β-induced Treg cells, but not natural Treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/Treg cell balance from Th17 predominance to Treg cell predominance.

S. Zheng, B. Ryffel, Zhongmin Liu, 2012, Arthritis and rheumatism.

Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer

D. Warburton, D. Menke, Wei Xu, 2013, BMC Biology.

Lung organogenesis.

D. Warburton, S. Bellusci, D. Riccardi, 2010, Current topics in developmental biology.

Development, repair and fibrosis: What is common and why it matters

D. Warburton, W. Shi, Jun Xu, 2009, Respirology.

Stem/progenitor cells in lung development, injury repair, and regeneration.

D. Warburton, S. Bellusci, B. Driscoll, 2008, Proceedings of the American Thoracic Society.

TGF-β receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung

D. Warburton, H. Moses, M. Kolb, 2008, European Respiratory Journal.

Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation.

D. Warburton, Y. Mishina, J. Whitsett, 2008, The American journal of pathology.

Functional analysis of the human Sprouty2 gene promoter.

D. Warburton, S. Bellusci, W. Ding, 2003, Gene.

Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry

V. Kaartinen, D. Warburton, S. Bellusci, 2003, Respiratory research.

Gremlin negatively modulates BMP-4 induction of embryonic mouse lung branching morphogenesis.

D. Warburton, K. Anderson, J. Zhao, 2001, American journal of physiology. Lung cellular and molecular physiology.

Smad7 and Smad6 Differentially Modulate Transforming Growth Factor β-induced Inhibition of Embryonic Lung Morphogenesis*

D. Warburton, Hui Chen, W. Shi, 2000, The Journal of Biological Chemistry.

Transforming Growth Factor-β Peptide Signaling in Pulmonary Development, Bronchopulmonary Dysplasia, Fibrosis, and Emphysema

D. Warburton, M. Kolb, J. Gauldie, 2005 .

Cartilage rings contribute to the proper embryonic tracheal epithelial differentiation, metabolism, and expression of inflammatory genes.

D. Warburton, M. Thornton, B. Grubbs, 2017, American journal of physiology. Lung cellular and molecular physiology.

Smad 3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

D. Warburton, Xiao-Fan Wang, M. Datto, 2002 .

miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution.

D. Guidolin, P. Parnigotto, D. Warburton, 2009, Developmental biology.

Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

S. Zheng, Y. Chai, Xuehao Wang, 2010, The Journal of Immunology.

Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis

W. Shi, Ming Liu, Dunqiang Ren, 2016, Stem Cell Research & Therapy.

Monocyte and macrophage derived myofibroblasts: Is it fate? A review of the current evidence

K. Ask, M. Vierhout, W. Shi, 2021, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Mesenchyme-specific deletion of Tgf-β1 in the embryonic lung disrupts branching morphogenesis and induces lung hypoplasia

D. Warburton, Gianluca Turcatel, W. Shi, 2019, Laboratory Investigation.

Restoration of intrahepatic regulatory T cells through MMP-9/13-dependent activation of TGF-β is critical for immune homeostasis following acute liver injury.

S. Zheng, Zanxian Xia, Guihua Chen, 2013, Journal of molecular cell biology.

Fibrosis, Adipogenesis, and Muscle Atrophy in Congenital Muscular Torticollis

W. Shi, Juan Cao, Sheng Tang, 2014, Medicine.

Strain-induced Differentiation of Fetal Type II Epithelial Cells Is Mediated via the Integrin α6β1-ADAM17/Tumor Necrosis Factor-α-converting Enzyme (TACE) Signaling Pathway*

D. Warburton, Zheping Huang, W. Shi, 2013, The Journal of Biological Chemistry.

Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice.

B. Driscoll, L. Barsky, J. Scholes, 2009, American journal of physiology. Lung cellular and molecular physiology.

Transforming Growth Factor-β1 Regulates Peroxisomal Genes/Proteins via Smad Signaling in Idiopathic Pulmonary Fibrosis Fibroblasts and Transgenic Mouse Models.

C. Ruppert, M. Bartkuhn, S. Karnati, 2022, The American journal of pathology.

Adoptive Transfer of Induced-Treg Cells Effectively Attenuates Murine Airway Allergic Inflammation

Hui Chen, Wei Xu, David Warburton, 2012, PloS one.

TGF-beta3-null mutation does not abrogate fetal lung maturation in vivo by glucocorticoids.

V. Kaartinen, D. Warburton, N. Heisterkamp, 1999, The American journal of physiology.

TGF-b 3-null mutation does not abrogate fetal lung maturation in vivo by glucocorticoids

V. Kaartinen, D. Warburton, N. Heisterkamp, 1999 .

TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism

E. Henske, S. Viswanathan, S. Ferguson, 2021, Nature Communications.

All-Trans Retinoic Acid Promotes TGF-β-Induced Tregs via Histone Modification but Not DNA Demethylation on Foxp3 Gene Locus

Wei Shi, Zanxian Xia, Song Guo Zheng, 2011, PloS one.

BMP4 Activation and Secretion Are Negatively Regulated by an Intracellular Gremlin-BMP4 Interaction*

D. Warburton, Hui Chen, W. Shi, 2006, Journal of Biological Chemistry.

Meningitic Escherichia coli K1 Penetration and Neutrophil Transmigration Across the Blood–Brain Barrier are Modulated by Alpha7 Nicotinic Receptor

A. Jong, Sheng-He Huang, Chun-Hua Wu, 2011, PloS one.

TGF-beta signaling promotes survival and repair in rat alveolar epithelial type 2 cells during recovery after hyperoxic injury.

D. Warburton, S. Buckley, L. Barsky, 2008, American journal of physiology. Lung cellular and molecular physiology.

Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema.

D. Warburton, Xiao-Fan Wang, S. Buckley, 2005, American journal of physiology. Lung cellular and molecular physiology.

Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells

J. Asara, E. Henske, S. El-Chemaly, 2021, Proceedings of the National Academy of Sciences.

Migration and gelatinases in cultured fetal, adult, and hyperoxic alveolar epithelial cells.

D. Warburton, B. Driscoll, S. Buckley, 2001, American journal of physiology. Lung cellular and molecular physiology.

A novel profibrotic mechanism mediated by TGFβ‐stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells

D. Warburton, M. Selman, Wei Xu, 2015, The Journal of pathology.

Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis.

D. Warburton, S. Frank, J. Peschon, 2001, Developmental biology.

Deficient Alk3-mediated BMP signaling causes prenatal omphalocele-like defect.

Y. Mishina, H. Ford, J. Upperman, 2007, Biochemical and biophysical research communications.

Smooth Muscle Differentiation Is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching.

Rongbo Li, Xin Sun, E. Hines, 2020, Developmental cell.

Histopathologic Features of Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins with Atypical Clinical Presentation.

D. Parham, Larry L. Wang, W. Shi, 2020, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development

D. Warburton, D. Menke, S. Bellusci, 2015, BMC Biology.

Myocd regulates airway smooth muscle cell remodeling in response to chronic asthmatic injury

M. Parmacek, Yongfeng Luo, Hui Chen, 2022, The Journal of pathology.

On growth and form of the distal air exchange surfaces within the lung

David S. Koos, D. Warburton, R. Moats, 2017, bioRxiv.

Mononuclear phagocytic system and fibrosis: back to the future?

K. Ask, M. Vierhout, W. Shi, 2021, European Respiratory Journal.