I. Astapova

发表

Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells.

J. Rossant, A. Zorn, R. Deterding, 2015, Cell stem cell.

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

D. Chuang, O. Ilkayeva, C. Newgard, 2018, Cell metabolism.

Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.

S. Balk, A. Hollenberg, I. Astapova, 2007, Cancer research.

The in vivo role of nuclear receptor corepressors in thyroid hormone action.

A. Hollenberg, I. Astapova, 2013, Biochimica et biophysica acta.

The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis.

A. Rosenzweig, Benjamin A. Rodwin, A. Hollenberg, 2011, Molecular endocrinology.

The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition

M. Herman, D. D’Alessio, J. Douros, 2020, Diabetes.

Thyroid Hormone Regulates Hepatic Expression of Fibroblast Growth Factor 21 in a PPARα-dependent Manner*

J. Flier, A. Hollenberg, E. Maratos-Flier, 2010, The Journal of Biological Chemistry.

Fibroblast growth factor 21 and thyroid hormone show mutual regulatory dependency but have independent actions in vivo.

J. Flier, A. Hollenberg, E. Maratos-Flier, 2014, Endocrinology.

Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1)

M. Willingham, O. Gavrilova, Sheue-yann Cheng, 2011, Proceedings of the National Academy of Sciences.

Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway.

R. H. Costa-e-Sousa, A. Hollenberg, D. Cohen, 2014, The Journal of clinical investigation.

PCR Amplification and Structural Analysis of Two Paralogous Rat Estrogen Sulfotransferase Genes

I. Astapova, A. N. Smirnov, P. Rubtsov, 2002, Molecular Biology.

Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha

Sheue-yann Cheng, A. Hollenberg, B. Freudenthal, 2019, Thyroid : official journal of the American Thyroid Association.

NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor

Linus T Tsai, A. Lyubetskaya, D. Tenen, 2017, Proceedings of the National Academy of Sciences.

The intestine is a major contributor to circulating succinate in mice

Guo-Fang Zhang, M. Herman, J. Rawls, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

NCoR1 and SMRT Play Unique Roles in Thyroid Hormone Action In Vivo

M. Bilban, A. Hollenberg, I. Astapova, 2014, Molecular and Cellular Biology.

“The Intestine is a Major Contributor to Circulating TCA Cycle Intermediates in Mice”

Guo-Fang Zhang, M. Herman, J. Rawls, 2022, bioRxiv.

Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition*

B. Singh, Sujoy Ghosh, A. Hollenberg, 2015, The Journal of Biological Chemistry.

TH regulates SIRT 1-RICTOR-AKT to activate FOXO 1 1 Hepatic FOXO 1 target genes are co-regulated by thyroid hormone via RICTOR deacetylation and MTORC 2-AKT inhibition *

B. Singh, Sujoy Ghosh, A. Hollenberg, 2015 .

Complex Role of the Vitamin D Receptor and Its Ligand in Adipogenesis in 3T3-L1 Cells*

J. Flier, A. Hollenberg, I. Astapova, 2006, Journal of Biological Chemistry.

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action

A. Rosenzweig, A. Hollenberg, I. Astapova, 2019, PloS one.

A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice

Mi-Sung Kim, M. Herman, I. Astapova, 2021, Nutrients.

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

M. Herman, M. Arlotto, I. Astapova, 2021, bioRxiv.

Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.

Robert C. Mines, Scott B. Crown, D. Hsu, 2018, Cell metabolism.

The Androgen Receptor Recruits Nuclear Receptor CoRepressor (N-CoR) in the Presence of Mifepristone via Its N and C Termini Revealing a Novel Molecular Mechanism for Androgen Receptor Antagonists*

S. Balk, A. Hollenberg, I. Astapova, 2005, Journal of Biological Chemistry.

The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo

M. Bilban, A. Hollenberg, I. Astapova, 2008, Proceedings of the National Academy of Sciences.

Role of co-regulators in metabolic and transcriptional actions of thyroid hormone.

I. Astapova, 2016, Journal of molecular endocrinology.

Thyroid Hormone Signaling In Vivo Requires a Balance between Coactivators and Corepressors

R. H. Costa-e-Sousa, A. Hollenberg, I. Astapova, 2014, Molecular and Cellular Biology.

The thyroid axis is regulated by NCoR1 via its actions in the pituitary.

F. Wondisford, R. H. Costa-e-Sousa, A. Hollenberg, 2012, Endocrinology.

Intestinal, but not hepatic, ChREBP is required for fructose tolerance.

M. Herman, S. Flier, G. Liang, 2017, JCI insight.

The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains

A. Hollenberg, I. Astapova, Melissa F. Dordek, 2009, Molecular and Cellular Endocrinology.

“Metformin Impairs Intestinal Fructose Metabolism”

Guo-Fang Zhang, M. Herman, I. Astapova, 2023, bioRxiv.

Metformin is a first-line anti-diabetic drug and the most

Guo-Fang Zhang, M. Herman, I. Astapova, 2023 .

Localization of a Site for Interaction with Hepatic Male-Specific Proteins in Two Rat Estrogen Sulfotransferase Genes

I. Astapova, A. N. Smirnov, P. Rubtsov, 2003, Biochemistry (Moscow).

Localization of Matrix-Associated Elements in the 5′-Region of the Rat Estrogen Sulfotransferase Gene

I. Astapova, A. N. Smirnov, P. Rubtsov, 2004, Russian Journal of Bioorganic Chemistry.

Intestinal, but not hepatic, ChREBP is required for fructose tolerance.

M. Herman, S. Flier, G. Liang, 2017, JCI insight.