I. Kozekov

发表

Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.

I. Minko, R. Lloyd, C. Rizzo, 2008, Accounts of chemical research.

New trans/cis tetrahydroisoquinolines. 1. trans-2-benzyl-3-(l-methyl-1h-pyrrol-2-yl)-4-substituted-1,2,3,4-tetrahydroisoquinolin-1-ones and corresponding tetrahydroisoquinolines

I. Kozekov, R. Koleva, M. Palamareva, 2002 .

Synthesis of new trans-2-benzyl-3-(furan-2-yl)-4-substituted-1,2,3,4-tetrahydroisoquinolinones.

I. Kozekov, M. Palamareva, M. Kandinska, 2006, Molecules.

New TRANS/CIS tetrahydroisoquinolines. 3. [1,3]‐oxazolo‐[3,2‐B]‐tetrahydroisoquinolinones having an angular aryl substituent

I. Kozekov, M. Palamareva, P. Christov, 2006 .

New trans/cis tetrahydroisoquinolines. 2. trans- and cis-3-(1-methyl-1h-pyrrol-2-yl)-1-(2H)-oxo-2-phenethyl-1,2,3,4-tetrahydroisoquino-lin-4-carboxylic acids and subsequent transformations

I. Kozekov, M. Palamareva, M. Stoyanova, 2003 .

Automatic Selection of Mobile Phases. III. TLC on Silica of 2,3,4‐Trisubstituted Tetrahydroisoquinolinones

I. Kozekov, M. Palamareva, M. Stoyanova, 2003 .

AUTOMATIC SELECTION OF MOBILE PHASES. TLC ON SILICA OF 2-BENZYL-3- (1-METHYLPYRROL-2-YL)-4-SUBSTITUTEDTETRAHYDROISOQUINOLINES AND CORRESPONDING 1-ONES

I. Kozekov, R. Koleva, M. Palamareva, 2001 .

DNA interchain cross-links formed by acrolein and crotonaldehyde.

L. Nechev, C. Rizzo, C. Harris, 2003, Journal of the American Chemical Society.

Stereospecific synthesis of oligonucleotides containing crotonaldehyde adducts of deoxyguanosine.

L. Nechev, C. Harris, T. Harris, 2001, Chemical research in toxicology.

Deoxyguanosine forms a bis-adduct with E,E-muconaldehyde, an oxidative metabolite of benzene: implications for the carcinogenicity of benzene.

C. Rizzo, C. Harris, T. Harris, 2011, Chemical research in toxicology.

Screening for DNA adducts by data-dependent constant neutral loss-triple stage mass spectrometry with a linear quadrupole ion trap mass spectrometer.

S. Spivack, S. Langouët, I. Kozekov, 2009, Analytical chemistry.

The formamidopyrimidine derivative of 7-(2-oxoethyl)-2'-deoxyguanosine.

C. Rizzo, T. Harris, I. Kozekov, 2008, Chemical research in toxicology.

Site-specific synthesis and characterization of oligonucleotides containing an N6-(2-deoxy-D-erythro-pentofuranosyl)-2,6-diamino-3,4-dihydro-4-oxo-5-N-methylformamidopyrimidine lesion, the ring-opened product from N7-methylation of deoxyguanosine.

C. Rizzo, T. Harris, M. Stone, 2008, Chemical research in toxicology.

Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy.

L. Marnett, C. Rizzo, T. Harris, 2006, Chemical research in toxicology.

Synthesis and mutagenesis of the butadiene-derived N3 2'-deoxyuridine adducts.

R. Lloyd, I. Kozekov, L. Hackfeld, 2006, Chemical research in toxicology.

A First-Level Analysis of The Adsorption Mechanism of Esters of Racemic and Meso-2,3-dibromobutane 1,4-dioic Acids on Silica

I. Kozekov, M. Palamareva, 1997 .

Chromatographic behaviour of diastereoisomers XIII. Adsorptivity of esters of Z- and E-2,3-diphenylpropenoic acids and similar compounds on silica in terms of the Snyder theory

I. Kozekov, M. Palamareva, 1997 .

Liquid-Solid Chromatography with Computer-Selected Mobile Phases on the Basis of Snyder Theory

I. Kozekov, M. Palamareva, 1996 .

Mechanism of 1,N2-etheno-2'-deoxyguanosine formation from epoxyaldehydes.

C. Rizzo, I. Kozekov, Katya V. Petrova, 2007, Chemical research in toxicology.

Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.

F. Guengerich, C. Rizzo, T. Harris, 2005, Chemical research in toxicology.

Formation of deoxyguanosine cross-links from calf thymus DNA treated with acrolein and 4-hydroxy-2-nonenal.

C. Rizzo, C. Harris, T. Harris, 2010, Chemical research in toxicology.

Interstrand DNA Cross‐Linking 1,N2‐Deoxyguanosine Adducts Derived from α,β‐Unsaturated Aldehydes: Structure–Function Relationships

I. Minko, R. Lloyd, C. Rizzo, 2010 .

DNA cross‐link induced by trans‐4‐hydroxynonenal

Hao Wang, R. Lloyd, C. Rizzo, 2010, Environmental and molecular mutagenesis.

Adducts of the r ,-Unsaturated Aldehydes Acrolein , Crotonaldehyde , and 4-Hydroxynonenal

I. Minko, R. Lloyd, C. Rizzo, 2009 .

Stereochemistry Modulates Stability of Reduced Inter-Strand Cross-Links Arising From R - and S - α -CH 3 - γ -OH-1, N 2 -propano-2 ′ Deoxyguanosine in the 5 ′ -CpG-3 ′ DNA Sequence

C. Rizzo, T. Harris, Young-jin Cho, 2008 .

Orientation of the crotonaldehyde-derived N2-[3-Oxo-1(S)-methyl-propyl]-dG DNA adduct hinders interstrand cross-link formation in the 5'-CpG-3' sequence.

Hao Wang, R. Lloyd, M. Voehler, 2006, Chemical research in toxicology.

Structure of the 1,N2-Ethenodeoxyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2†

F. Guengerich, C. Rizzo, M. Stone, 2008, Chemical research in toxicology.

Stereochemistry modulates the stability of reduced interstrand cross-links arising from R- and S-alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine in the 5'-CpG-3' DNA sequence.

C. Rizzo, T. Harris, Young-jin Cho, 2007, Biochemistry.

Site-specific synthesis and reactivity of oligonucleotides containing stereochemically defined 1,N2-deoxyguanosine adducts of the lipid peroxidation product trans-4-hydroxynonenal.

C. Rizzo, T. Harris, I. Kozekov, 2003, Journal of the American Chemical Society.

Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases.

Urban Bren, F. Guengerich, C. Rizzo, 2009, Journal of molecular biology.

Chromatographic behaviour of diastereoisomers XII. Effects of alumina on separations of esters of maleic and fumaric acids

I. Kozekov, M. Palamareva, I. Jurova, 1994 .

Versatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts*

M. Egli, F. Guengerich, C. Rizzo, 2009, Journal of Biological Chemistry.

Replication of N2,3-ethenoguanine by DNA polymerases.

M. Egli, F. Guengerich, C. Rizzo, 2012, Angewandte Chemie.

Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).

F. Guengerich, C. Rizzo, M. Stone, 2010, Chemical research in toxicology.

Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.

M. O’Donnell, I. Minko, R. Lloyd, 2008, Chemical research in toxicology.

Translesion synthesis across 1,N2-ethenoguanine by human DNA polymerases.

F. Guengerich, C. Rizzo, I. Kozekov, 2006, Chemical research in toxicology.

DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine.

L. Nechev, C. Rizzo, T. Harris, 2002, Chemical research in toxicology.

Role for DNA Polymerase κ in the Processing of N2-N2-Guanine Interstrand Cross-links*

R. Moses, I. Minko, R. Lloyd, 2008, Journal of Biological Chemistry.

1,N2-Etheno-2′-deoxyguanosine Adopts the syn Conformation about the Glycosyl Bond When Mismatched with Deoxyadenosine

F. Guengerich, C. Rizzo, M. Stone, 2011, Chemical research in toxicology.

Structure of the 1,N2-Etheno-2′-deoxyguanosine Lesion in the 3′-G(εdG)T-5′ Sequence Opposite a One-Base Deletion†

F. Guengerich, C. Rizzo, M. Stone, 2010, Biochemistry.

Oxidation and Glycolytic Cleavage of Etheno and Propano DNA Base Adducts†

L. Marnett, F. Guengerich, C. Rizzo, 2009, Biochemistry.

Structure of the 1,N2-etheno-2'-deoxyguanosine adduct in duplex DNA at pH 8.6.

F. Guengerich, C. Rizzo, M. Stone, 2007, Chemical research in toxicology.

DNA Adduct Bypass Polymerization by Sulfolobus solfataricus DNA Polymerase Dpo4

M. Egli, F. Guengerich, A. Irimia, 2005, Journal of Biological Chemistry.

Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts.

I. Minko, R. Lloyd, C. Rizzo, 2008, Mutation research.

Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.

Hao Wang, I. Minko, R. Lloyd, 2005, Journal of the American Chemical Society.

Formation of inter- and intrastrand imine type DNA-DNA cross-links through secondary reactions of aldehydic adducts.

R. Lloyd, T. Harris, I. Kozekov, 2005, Chemical research in toxicology.

Interchain cross-linking of DNA mediated by the principal adduct of acrolein.

R. Lloyd, L. Nechev, C. Harris, 2001, Chemical research in toxicology.

Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N2-γ-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage†,‡

R. Lloyd, C. Rizzo, A. McCullough, 2010, Biochemistry.

Chemistry and Biology of DNA Containing 1,N2-Deoxyguanosine Adducts of the α,β-Unsaturated Aldehydes Acrolein, Crotonaldehyde, and 4-Hydroxynonenal

I. Minko, R. Lloyd, C. Rizzo, 2009, Chemical research in toxicology.

Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.

Hao Wang, C. Rizzo, T. Harris, 2009, Journal of the American Chemical Society.

Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes.

M. Egli, F. Guengerich, C. Rizzo, 2009, The Journal of biological chemistry.

Novel Enzymatic Function of DNA Polymerase ν in Translesion DNA Synthesis Past Major Groove DNA−Peptide and DNA−DNA Cross-Links

R. Wood, K. Takata, I. Minko, 2010, Chemical research in toxicology.

Stereospecific Formation of Interstrand Carbinolamine DNA Cross-Links by Crotonaldehyde- and Acetaldehyde-Derived α-CH3-γ-OH-1,N2-Propano-2‘-deoxyguanosine Adducts in the 5‘-CpG-3‘ Sequence

R. Lloyd, M. Voehler, C. Rizzo, 2006 .

Ring-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4

M. Egli, I. Minko, R. Lloyd, 2013, Chemical research in toxicology.

Mechanism of Repair of Acrolein- and Malondialdehyde-Derived Exocyclic Guanine Adducts by the α-Ketoglutarate/Fe(II) Dioxygenase AlkB

L. Marnett, J. Essigmann, C. Rizzo, 2014, Chemical research in toxicology.

Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequence.

Hao Wang, R. Lloyd, M. Voehler, 2006, Chemical research in toxicology.

Checkpoint signaling from a single DNA interstrand crosslink.

J. Gautier, M. Gottesman, C. Rizzo, 2009, Molecular cell.

Coupling products of nucleosides with the glyoxal adduct of deoxyguanosine.

C. Rizzo, T. Harris, I. Kozekov, 2004, Chemical Research in Toxicology.

Checkpoint signaling from a single DNA interstrand crosslink.

J. Gautier, M. Gottesman, C. Rizzo, 2009, Molecular cell.

Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.

I. Minko, R. Lloyd, C. Rizzo, 2008, Accounts of chemical research.

Comparison of the in vitro replication of the 7-(2-oxoheptyl)-1,N2-etheno-2'-deoxyguanosine and 1,N2-etheno-2'-deoxyguanosine lesions by Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).

C. Rizzo, I. Kozekov, Albena Kozekova, 2010, Chemical research in toxicology.

Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family.

I. Minko, C. Rizzo, I. Kozekov, 2008, Chemical research in toxicology.

Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4

M. Egli, C. Rizzo, I. Kozekov, 2009, The Journal of Biological Chemistry.

Stereospecific formation of the (R)-gamma-hydroxytrimethylene interstrand N2-dG:N2-dG cross-link arising from the gamma-OH-1,N2-propano-2'-deoxyguanosine adduct in the 5'-CpG-3' DNA sequence.

Hao Wang, C. Rizzo, T. Harris, 2009, Journal of the American Chemical Society.