L. de Ridder

发表

The duration of effect of infliximab maintenance treatment in paediatric Crohn’s disease is limited

J. Schweizer, P. V. van Rheenen, C. Kneepkens, 2011, Alimentary pharmacology & therapeutics.

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease.

A. Griffiths, J. Hugot, G. Veres, 2014, Journal of Crohn's & colitis.

Adalimumab Therapy in Children With Crohn Disease Previously Treated With Infliximab

P. V. van Rheenen, T. D. de Meij, A. Kindermann, 2015, Journal of pediatric gastroenterology and nutrition.

Vedolizumab in Paediatric Inflammatory Bowel Disease: A Retrospective Multi-Centre Experience From the Paediatric IBD Porto Group of ESPGHAN

V. Wolters, H. Uhlig, K. Kolho, 2017, Journal of Crohn's & colitis.

Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease.

H. Tilg, C. Lees, Y. Yazdanpanah, 2009, Journal of Crohn's & colitis.

Infliximab as first-line therapy in severe pediatric Crohn disease.

D. Hommes, M. Benninga, J. Taminiau, 2006, Journal of pediatric gastroenterology and nutrition.

Management of Pediatric Ulcerative Colitis: Joint ECCO and ESPGHAN Evidence-based Consensus Guidelines

David C. Wilson, A. Griffiths, J. Hugot, 2012, Journal of pediatric gastroenterology and nutrition.

Risk of Infection and Prevention in Pediatric Patients With IBD: ESPGHAN IBD Porto Group Commentary

G. Veres, J. Rahier, J. Fell, 2012, Journal of pediatric gastroenterology and nutrition.

Protocol for a multinational risk-stratified randomised controlled trial in paediatric Crohn’s disease: methotrexate versus azathioprine or adalimumab for maintaining remission in patients at low or high risk for aggressive disease course

R. Russell, M. Neyt, D. Turner, 2020, BMJ Open.

Nutrition in Paediatric Inflammatory Bowel Disease: A Position Paper on Behalf of The Porto IBD Group of ESPGHAN.

R. Russell, A. Staiano, E. Miele, 2018, Journal of pediatric gastroenterology and nutrition.

Malignancy and mortality in paediatric‐onset inflammatory bowel disease: a 3‐year prospective, multinational study from the paediatric IBD Porto group of ESPGHAN

G. Veres, P. Lionetti, K. Kolho, 2018, Alimentary Pharmacology and Therapeutics.

Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis—An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis; An Evidence-based Consensus Guideline from ECCO and ESPGHAN.

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World

A. Griffiths, D. Turner, J. Hyams, 2018, Canadian journal of gastroenterology & hepatology.

Venous Thromboembolic Complications in Pediatric Gastrointestinal Diseases: Inflammatory Bowel Disease and Intestinal Failure

L. de Ridder, B. D. de Koning, R. Klomberg, 2022, Frontiers in Pediatrics.

[Guideline 'Diagnosis and treatment of inflammatory bowel disease in children'].

E. Rings, J. Escher, L. de Ridder, 2010, Nederlands tijdschrift voor geneeskunde.

Infliximab dependency in pediatric Crohn's disease: Long‐term follow‐up of an unselected cohort

J. Schweizer, E. Rings, M. Benninga, 2008, Inflammatory bowel diseases.

Infliximab Use in Children and Adolescents With Inflammatory Bowel Disease

D. Hommes, S. V. van Deventer, M. Benninga, 2007, Journal of pediatric gastroenterology and nutrition.

Infliximab Therapy in 30 Patients With Refractory Pediatric Crohn Disease With and Without Fistulas in The Netherlands

R. Houwen, J. Schweizer, E. Rings, 2004, Journal of pediatric gastroenterology and nutrition.

Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort.

C. Sokollik, I. Lindberg, Martín G. Martín, 2013, Gastroenterology.

C. Strisciuglio, P. Lionetti, D. Turner, 2015, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

Changes in Natural Foxp3+Treg but Not Mucosally-Imprinted CD62LnegCD38+Foxp3+Treg in the Circulation of Celiac Disease Patients

C. Mulder, J. Samsom, J. Escher, 2013, PloS one.

Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary

A. Griffiths, R. Baldassano, M. Dubinsky, 2019, Gut.

Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care- an Evidence-Based Guideline from ECCO and ESPGHAN.

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

Diagnostic and Therapeutic Approach in Paediatric Inflammatory Bowel Diseases: Results from a Clinical Practice Survey

A. Griffiths, O. Hradsky, J. Bronský, 2019, Journal of pediatric gastroenterology and nutrition.

Predicting Outcomes in Pediatric Crohn's Disease for Management Optimization: Systematic Review and Consensus Statements from PIBD-Ahead Program.

A. Griffiths, M. Dubinsky, G. Veres, 2020, Gastroenterology.

The Incidence and Characteristics of Venous Thromboembolisms in Paediatric-Onset Inflammatory Bowel Disease: A Prospective International Cohort Study Based on the PIBD-SETQuality Safety Registry

M. Aardoom, H. van Ommen, L. de Ridder, 2021, Journal of Crohn's & colitis.

Manifestations of Munchausen syndrome by proxy in pediatric gastroenterology.

J. Hoekstra, L. de Ridder, 2000, Journal of pediatric gastroenterology and nutrition.

Use of Placebo in Pediatric Inflammatory Bowel Diseases: A Position Paper From ESPGHAN, ECCO, PIBDnet, and the Canadian Children IBD Network

A. Griffiths, M. Dubinsky, S. Vermeire, 2016, Journal of pediatric gastroenterology and nutrition.

Cannabis, a potential treatment option in pediatric IBD? Still a long way to go

L. de Ridder, M. Groeneweg, Nienke M Halbmeijer, 2019, Expert review of clinical pharmacology.

Evaluation of exclusive enteral nutrition and corticosteroid induction treatment in new-onset moderate-to-severe luminal paediatric Crohn’s disease

V. Wolters, K. Kolho, T. D. de Meij, 2022, European Journal of Pediatrics.

The Medical Management of Paediatric Crohn's Disease: an ECCO-ESPGHAN Guideline Update.

A. Griffiths, R. Russell, P. V. van Rheenen, 2020, Journal of Crohn's & colitis.

Antitumor necrosis factor treatment for pediatric inflammatory bowel disease

J. Escher, C. D. de Bie, L. de Ridder, 2012, Inflammatory bowel diseases.

High intra‐uterine exposure to infliximab following maternal anti‐TNF treatment during pregnancy

E. Kuipers, M. Peppelenbosch, C. J. van der Woude, 2011, Alimentary pharmacology & therapeutics.

Quality of care standards in inflammatory bowel diseases: a European Crohn's and Colitis Organisation (ECCO) position paper.

J. Gisbert, A. Hart, G. Fiorino, 2020, Journal of Crohn's & colitis.

G. Veres, R. Russell, V. Wolters, 2019, Journal of pediatric gastroenterology and nutrition.

Paediatric Inflammatory Bowel Disease: A Multi-Stakeholder Perspective to Improve Development of Drugs for Children and Adolescents

A. Griffiths, G. Vassal, D. Turner, 2022, Journal of Crohn's & colitis.

A Review on the Use of Anti-TNF in Children and Adolescents with Inflammatory Bowel Disease

M. Aardoom, L. de Ridder, G. Veereman, 2019, International journal of molecular sciences.

Anti-Tumour Necrosis Factor Therapy for Paediatric Crohn’s Disease: Improved Benefits Through Treatment Optimisation, Deeper Understanding of Its Risks, and Reduced Costs due to Biosimilar Availability

J. Samsom, L. de Ridder, M. Cozijnsen, 2017, Pediatric Drugs.

Top-down Infliximab Study in Kids with Crohn's disease (TISKids): an international multicentre randomised controlled trial

J. Samsom, J. Escher, L. de Ridder, 2016, BMJ open gastroenterology.

Thromboprophylaxis Use in Paediatric Inflammatory Bowel Disease: An International RAND Appropriateness Panel

M. Samaan, E. Benchimol, R. Hansen, 2022, Journal of Crohn's & colitis.

High impact of pediatric inflammatory bowel disease on caregivers' work productivity and daily activities: an international prospective study.

D. Rizopoulos, M. Neyt, M. Aardoom, 2022, The Journal of pediatrics.

Infliximab in young paediatric IBD patients: it is all about the dosing

D. Rizopoulos, V. Wolters, K. Kolho, 2020, European Journal of Pediatrics.

Methotrexate for maintaining remission in paediatric Crohn's patients with prior failure or intolerance to thiopurines: a multicenter cohort study.

M. Mearin, P. V. van Rheenen, T. D. de Meij, 2015, Journal of Crohn's & colitis.

First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn’s disease: an open-label multicentre randomised controlled trial

D. Rizopoulos, V. Wolters, P. V. van Rheenen, 2020, Gut.

Predicting Outcomes in Pediatric Ulcerative Colitis for Management Optimization: Systematic Review and Consensus Statements from PIBD-Ahead Program.

A. Griffiths, M. Dubinsky, G. Veres, 2020, Gastroenterology.

Complications of single-balloon enteroscopy: a prospective evaluation of 166 procedures.

E. Kuipers, J. Haringsma, L. de Ridder, 2010, Endoscopy.

Complications and Disease Recurrence After Primary Ileocecal Resection in Pediatric Crohn's Disease: A Multicenter Cohort Analysis

M. Mearin, V. Wolters, P. V. van Rheenen, 2016, Inflammatory bowel diseases.

Azathioprine maintains first remission in newly diagnosed pediatric Crohn's disease.

E. Rings, H. Verkade, J. Taminiau, 2006, Inflammatory bowel diseases.

Azathioprine Maintains first remission in newly diagnosed pediatric Crohn's disease

E. Rings, H. Verkade, J. Taminiau, 2006, Inflammatory bowel diseases.

Malignancy and Mortality in Pediatric Patients with Inflammatory Bowel Disease: A Multinational Study from the Porto Pediatric IBD Group

G. Veres, P. Lionetti, K. Kolho, 2014, Inflammatory bowel diseases.

Editorial: implications and future perspectives of the increase in biologics use in paediatric inflammatory bowel disease

L. de Ridder, S. Vuijk, 2022, Alimentary pharmacology & therapeutics.

Diagnostic Workup of Paediatric Patients With Inflammatory Bowel Disease in Europe: Results of a 5-Year Audit of the EUROKIDS Registry

G. Veres, J. Escher, C. D. de Bie, 2012, Journal of pediatric gastroenterology and nutrition.

Health Care Transition Outcomes in Inflammatory Bowel Disease: A Multinational Delphi Study

C. J. van der Woude, J. Escher, L. de Ridder, 2019, Journal of Crohn's & colitis.

Self‐efficacy did not predict the outcome of the transition to adult care in adolescents with inflammatory bowel disease

C. J. van der Woude, J. Escher, L. de Ridder, 2018, Acta paediatrica.

Endoscopy in Pediatric Inflammatory Bowel Disease: A Position Paper on Behalf of the Porto IBD Group of the Espghan.

E. Miele, N. Afzal, M. Thomson, 2018, Journal of pediatric gastroenterology and nutrition.

Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood: A European Society for Paediatric Gastroenterology Hepatology and Nutrition Position Paper

E. Miele, M. Benninga, M. Thomson, 2021 .

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease.

M. Toruner, S. Vavricka, U. Kopylov, 2021, Journal of Crohn's & colitis.

Clinical Genomics for the Diagnosis of Monogenic Forms of Inflammatory Bowel Disease: A Position Paper From the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology and Nutrition

A. Griffiths, C. Klein, S. Travis, 2020, Journal of Pediatric Gastroenterology & Nutrition.

IL-10 signaling in dendritic cells controls IL-1β-mediated IFNγ secretion by human CD4+ T cells: relevance to inflammatory bowel disease

D. Winter, M. Van Leeuwen, L. de Ridder, 2019, Mucosal Immunology.

Clinical Genomics for the Diagnosis of Monogenic forms of Inflammatory Bowel Disease: A Position Paper from The Paediatric IBD Porto Group of ESPGHAN.

A. Griffiths, C. Klein, S. Travis, 2020, Journal of pediatric gastroenterology and nutrition.

Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care—An Evidence-based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition

A. Griffiths, G. Veres, R. Russell, 2018, Journal of pediatric gastroenterology and nutrition.

ESPGHAN Revised Porto Criteria for the Diagnosis of Inflammatory Bowel Disease in Children and Adolescents

G. Veres, R. Russell, A. Staiano, 2013, Journal of pediatric gastroenterology and nutrition.

Development and Validation of the Mucosal Inflammation Noninvasive Index For Pediatric Crohn's Disease.

A. Griffiths, R. Russell, T. Walters, 2019, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Genetic susceptibility has a more important role in pediatric‐onset Crohn's disease than in adult‐onset Crohn's disease

D. Hommes, I. Nolte, R. Weersma, 2007, Inflammatory bowel diseases.

Self-efficacy in adolescents with inflammatory bowel disease: a pilot study of the "IBD-yourself", a disease-specific questionnaire.

J. Escher, C. D. de Bie, L. de Ridder, 2013, Journal of Crohn's & colitis.

Malignancy and Mortality in Pediatric-onset Inflammatory Bowel Disease: A Systematic Review.

M. Aardoom, A. Levine, L. de Ridder, 2018, Inflammatory bowel diseases.

Percutaneous endoscopic gastrostomy (PEG) in children is not a minor procedure: risk factors for major complications.

W. Hop, J. Escher, L. de Ridder, 2009, Seminars in pediatric surgery.

Nutrition in Pediatric Inflammatory Bowel Disease: A Position Paper on Behalf of the Porto Inflammatory Bowel Disease Group of the European Society of Pediatric Gastroenterology, Hepatology and Nutrition

R. Russell, A. Staiano, E. Miele, 2018, Journal of pediatric gastroenterology and nutrition.

Results of the 2nd part Scientific Workshop of the ECCO. II: Measures and markers of prediction to achieve, detect, and monitor intestinal healing in inflammatory bowel disease.

M. Färkkilä, I. Dotan, P. Lakatos, 2011, Journal of Crohn's & colitis.

Development and Function of Immune Cells in an Adolescent Patient With a Deficiency in the Interleukin-10 Receptor.

G. Driessen, D. Halley, K. Biermann, 2017, Journal of pediatric gastroenterology and nutrition.

Outcomes Following Pouch Formation in Paediatric Ulcerative Colitis: A Study from the Porto Group of ESPGHAN.

B. Weiss, I. Dotan, C. Strisciuglio, 2020, Journal of pediatric gastroenterology and nutrition.

Single-balloon enteroscopy, magnetic resonance enterography, and abdominal US useful for evaluation of small-bowel disease in children with (suspected) Crohn's disease.

M. Lequin, C. J. van der Woude, R. D. de Krijger, 2012, Gastrointestinal endoscopy.

Enteroscopy in paediatric Crohn's disease.

G. Di Nardo, S. Cucchiara, J. Escher, 2013, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

A Simple Endoscopic Score Modified for the Upper Gastrointestinal Tract in Crohn’s Disease [UGI-SES-CD]: A Report From the ImageKids Study

A. Griffiths, J. Kelsen, M. Amitai, 2018, Journal of Crohn's & colitis.

Safety of Thioguanine in Pediatric Inflammatory Bowel Disease: A Multi-Center Case Series

C. Mulder, V. Wolters, M. Benninga, 2022, Journal of pediatric gastroenterology and nutrition.

Editorial: achievements and unresolved questions in improving the pharmacokinetics of vedolizumab in adolescents with inflammatory bowel disease

L. de Ridder, S. Vuijk, 2023, Alimentary pharmacology & therapeutics.

Limitations of Fecal Calprotectin At Diagnosis in Untreated Pediatric Crohn's Disease

G. Veres, P. Lionetti, K. Kolho, 2012, Inflammatory bowel diseases.

The diagnosis and management of CMV colitis in IBD patients shows high practice variation: a national survey among gastroenterologists

C. J. van der Woude, A. A. van der Eijk, L. de Ridder, 2022, Scandinavian journal of gastroenterology.

Pharmacokinetics, Pharmacodynamics and Immunogenicity of Infliximab in Paediatric Inflammatory Bowel Disease; a Systematic Review and Revised Dosing Considerations.

J. Taminiau, S. D. de Wildt, J. Escher, 2020, Journal of pediatric gastroenterology and nutrition.

Rectal bleeding in children: endoscopic evaluation revisited

M. Benninga, J. Taminiau, L. de Ridder, 2007, European journal of gastroenterology & hepatology.

Rapid Test for Fecal Calprotectin Levels in Children With Crohn Disease

G. Veres, A. Staiano, D. Turner, 2012, Journal of pediatric gastroenterology and nutrition.

International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study

R. Russell, M. Neyt, T. Walters, 2020, BMJ Open.

The use of biosimilars in paediatric inflammatory bowel disease

A. Vulto, L. de Ridder, M. Jongsma, 2017, Current opinion in pediatrics.

Predictive Prenatal Diagnosis for Infantile-Onset Inflammatory Bowel Disease due to Interleukin-10 Signalling Defects.

H. Kanegane, C. Klein, S. Snapper, 2020, Journal of pediatric gastroenterology and nutrition.

Benefits and Risks of Combining Anti-tumor Necrosis Factor with Immunomodulator Therapy in Pediatric Inflammatory Bowel Disease

A. Griffiths, D. Turner, J. Escher, 2015, Inflammatory bowel diseases.

Identifying Health Economic Considerations to Include in the Research Protocol of a Randomized Controlled Trial (the REDUCE-RISK Trial): Systematic Literature Review and Assessment

R. Russell, M. Neyt, D. Turner, 2021, JMIR formative research.

Magnetic Resonance Enterography for Suspected Inflammatory Bowel Disease in a Pediatric Population

J. Stoker, M. V. van Leeuwen, R. Houwen, 2010, Journal of pediatric gastroenterology and nutrition.

Rotterdam Transition Test: A Valid Tool for Monitoring Disease Knowledge in Adolescents With Inflammatory Bowel Disease

D. Rizopoulos, C. J. van der Woude, J. Escher, 2021, Journal of pediatric gastroenterology and nutrition.

Endoscopy in Pediatric Inflammatory Bowel Disease: A Position Paper on Behalf of the Porto IBD Group of the Espghan.

E. Miele, N. Afzal, M. Thomson, 2018, Journal of pediatric gastroenterology and nutrition.

Infliximab Level Between Venous and Capillary Blood Using Novel Device Strongly Correlate in Paediatric Inflammatory Bowel Disease Patients

L. de Ridder, A. de Vries, K. Bloem, 2020, Journal of pediatric gastroenterology and nutrition.

Vedolizumab in paediatric IBD: a huge step forward but not there yet.

L. de Ridder, R. Klomberg, 2023, The lancet. Gastroenterology & hepatology.

Vedolizumab Trough Levels in Children With Anti-Tumor Necrosis Factor Refractory Inflammatory Bowel Disease

M. Aardoom, J. Escher, L. de Ridder, 2020, Journal of pediatric gastroenterology and nutrition.

Quality of life and colorectal function in Crohn’s disease patients that underwent ileocecal resection during childhood

M. Mearin, V. Wolters, P. V. van Rheenen, 2019, European Journal of Pediatrics.

Small bowel endoscopy in children.

J. Escher, L. de Ridder, M. Tabbers, 2012, Best practice & research. Clinical gastroenterology.

ECCO Guidelines on Inflammatory Bowel Disease and Malignancies.

T. Molnár, S. Vavricka, U. Kopylov, 2022, Journal of Crohn's & colitis.

Cytomegalovirus Infection in Pediatric Severe Ulcerative Colitis-A Multicenter Study from the Pediatric Inflammatory Bowel Disease Porto Group of the European Society of Pediatric Gastroenterology, Hepatology and Nutrition.

V. Wolters, U. Kopylov, T. D. de Meij, 2017 .

New Kids in the Neighborhood: Biosimilars.

H. Winter, L. de Ridder, 2017, Journal of pediatric gastroenterology and nutrition.

Dual Biologic or Small Molecule Therapy in Refractory Pediatric Inflammatory Bowel Disease (DOUBLE-PIBD): A Multicenter Study from the Pediatric IBD Porto Group of ESPGHAN.

K. Kolho, B. Kang, M. Bramuzzo, 2023, Inflammatory bowel diseases.

Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Infliximab in Pediatric Inflammatory Bowel Disease: A Systematic Review and Revised Dosing Considerations.

J. Taminiau, S. D. de Wildt, J. Escher, 2020, Journal of pediatric gastroenterology and nutrition.

Eosinophilic myenteric ganglionitis as a cause of chronic intestinal pseudo-obstruction

R. D. de Krijger, J. Hulst, J. Verheij, 2011, Virchows Archiv.

Serum Immune Profiling in Paediatric Crohn’s Disease Demonstrates Stronger Immune Modulation With First-Line Infliximab Than Conventional Therapy and Pre-Treatment Profiles Predict Clinical Response to Both Treatments

J. Samsom, J. Escher, L. de Ridder, 2023, Journal of Crohn's & Colitis.

The Continental Divide: Anti-TNF Use in Pediatric IBD Is Different in North America Compared to Other Parts of the World

A. Griffiths, D. Turner, J. Hyams, 2018, Canadian journal of gastroenterology & hepatology.

Validation and Reference Scores of the Transition Readiness Assessment Questionnaire in Adolescent and Young Adult IBD Patients

J. Escher, L. de Ridder, D. Rizopoulos, 2023, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

Validation of predictive models for disease outcomes in paediatric ulcerative colitis: A multicentre prospective inception cohort

B. Choe, B. Kang, D. Shouval, 2023, Alimentary pharmacology & therapeutics.

A. Griffiths, G. Veres, C. Strisciuglio, 2018, Journal of pediatric gastroenterology and nutrition.

Precision medicine in monogenic inflammatory bowel disease: proposed mIBD REPORT standards

S. Snapper, D. Shouval, D. McGovern, 2023, Nature Reviews Gastroenterology & Hepatology.

Antitumor necrosis factor treatment for pediatric inflammatory bowel disease

J. Escher, C. D. de Bie, L. de Ridder, 2012, Inflammatory bowel diseases.

C. Strisciuglio, P. Lionetti, D. Turner, 2015, Journal of pediatric gastroenterology and nutrition.

ECCO Topical Review on Clinicopathological Spectrum & Differential Diagnosis of IBD.

V. Villanacci, J. Burisch, A. Mookhoek, 2021, Journal of Crohn's & Colitis.

Diagnosis, Management, and Prevention of Button Battery Ingestion in Childhood: A European Society for Paediatric Gastroenterology Hepatology and Nutrition Position Paper

E. Miele, M. Benninga, M. Thomson, 2021, Journal of pediatric gastroenterology and nutrition.