I. Heinonen

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The Effect of Commercial Activity Tracker Based Physical Activity Intervention on Body Composition and Cardiometabolic Health Among Recent Retirees

S. Stenholm, J. Vahtera, J. Pentti, 2021, Frontiers in Aging.

Both sedentary time and physical activity are associated with cardiometabolic health in overweight adults in a 1 month accelerometer measurement

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2020, Scientific Reports.

Regulation of human skeletal muscle perfusion and its heterogeneity during exercise in moderate hypoxia.

V. Oikonen, J. Knuuti, R. Boushel, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Regulation of bone blood flow in humans: The role of nitric oxide, prostaglandins, and adenosine

Y. Hellsten, R. Boushel, K. Kalliokoski, 2018, Scandinavian journal of medicine & science in sports.

during cycle ramp exercise activation in different muscles of the quadriceps The relationship between muscle deoxygenation and

T. Barstow, J. Hannukainen, H. Rossiter, 2015 .

during exercise in humans Regulation of subcutaneous adipose tissue blood flow

J. Knuuti, S. Zakynthinos, R. Boushel, 2015 .

muscleon energy substrate utilization of human skeletal Effects of adenosine, exercise, and moderate acute

J. Knuuti, R. Boushel, P. Nuutila, 2013 .

Effect of nitric oxide synthase inhibition on the exchange of glucose and fatty acids in human skeletal muscle

Y. Hellsten, B. Saltin, J. Knuuti, 2013, Nutrition and Metabolism.

Regulation of subcutaneous adipose tissue blood flow during exercise in humans.

J. Knuuti, R. Boushel, P. Nuutila, 2012, Journal of applied physiology.

Local heating, but not indirect whole body heating, increases human skeletal muscle blood flow.

Juhani Knuuti, Craig G Crandall, Jukka Kemppainen, 2011, Journal of applied physiology.

Increase of Glucose Uptake in Human Bone Marrow With Increasing Exercise Intensity.

J. Knuuti, J. Kemppainen, K. Kalliokoski, 2019, International journal of sport nutrition and exercise metabolism.

Effects of heat and cold on health, with special reference to Finnish sauna bathing.

J. Laukkanen, I. Heinonen, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

INCREASING EXERCISE INTENSITY INCREASES GLUCOSE UPTAKE IN HUMAN BONE MARROW

J. Knuuti, J. Kemppainen, I. Heinonen, 2018 .

Bone blood flow and metabolism in humans: Effect of muscular exercise and other physiological perturbations

H. Langberg, J. Knuuti, M. Kjaer, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Role of adenosine in regulating the heterogeneity of skeletal muscle blood flow during exercise in humans.

S. Nesterov, J. Knuuti, M. Kjaer, 2007, Journal of applied physiology.

Evidence for Shear Stress–Mediated Dilation of the Internal Carotid Artery in Humans

P. Ainslie, D. Green, Andrew Haynes, 2016, Hypertension.

Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men.

J. Hannukainen, E. Löyttyniemi, K. Kalliokoski, 2016, American journal of physiology. Heart and circulatory physiology.

Objectively measured sedentary time before and after transition to retirement:The Finnish Retirement and Aging Study (FIREA).

S. Stenholm, J. Vahtera, J. Pentti, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

subjectsendurance athletes and healthy control Pulmonary blood flow and its distribution in highly

J. Knuuti, J. Hannukainen, P. Nuutila, 2014 .

Influence of the Duration and Timing of Data Collection on Accelerometer-Measured Physical Activity, Sedentary Time and Associated Insulin Resistance

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2021, International journal of environmental research and public health.

ventilationmaps of regional blood flow and regional

R. Glenny, V. Oikonen, J. Knuuti, 2013 .

artery, a possible causative factor of heatstroke Hyperthermia-induced vasoconstriction of the carotid

J. Knuuti, C. Crandall, Y. Shiu, 2015 .

Combined effects of continuous exercise and intermittent active interruptions to prolonged sitting on postprandial glucose, insulin, and triglycerides in adults with obesity: a randomized crossover trial

N. Owen, D. Dunstan, E. Cerin, 2020, International Journal of Behavioral Nutrition and Physical Activity.

Systemic Hypoxia Increases Circulating Concentration of Apelin in Humans.

O. Vuolteenaho, M. Nikinmaa, J. Koskenvuo, 2017, High altitude medicine & biology.

Animal models of heart failure with preserved ejection fraction

D. Duncker, I. Falcão-Pires, I. Heinonen, 2016, Netherlands Heart Journal.

Cool-Water Immersion Reduces Postexercise Quadriceps Femoris Muscle Perfusion More Than Cold-Water Immersion

D. Low, V. Di Salvo, Lorenzo Lolli, 2022, Medicine and science in sports and exercise.

Effects of adenosine, exercise, and moderate acute hypoxia on energy substrate utilization of human skeletal muscle.

H. Sipilä, J. Knuuti, R. Boushel, 2012, American Journal of Physiology. Regulatory Integrative and Comparative Physiology.

The Circulatory and Metabolic Responses to Hypoxia in Humans – With Special Reference to Adipose Tissue Physiology and Obesity

R. Boushel, K. Kalliokoski, I. Heinonen, 2016, Front. Endocrinol..

Capacity and hypoxic response of subcutaneous adipose tissue blood flow in humans.

J. Knuuti, R. Boushel, K. Kaskinoro, 2014, Circulation journal : official journal of the Japanese Circulation Society.

Relationship between liver fat content and lifestyle factors in adults with metabolic syndrome

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2022, Scientific Reports.

Cross-Sectional Associations of Body Adiposity, Sedentary Behavior, and Physical Activity with Hemoglobin and White Blood Cell Count

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2022, International journal of environmental research and public health.

Short-term exercise affects cardiac function ex vivo partially via changes in calcium channel levels, without influencing hypoxia sensitivity

T. Streng, K. Anttila, I. Heinonen, 2021, Journal of physiology and biochemistry.

Heterogeneity of Muscle Blood Flow and Metabolism: Influence of Exercise, Aging, and Disease States

D. Poole, K. Kalliokoski, I. Heinonen, 2015, Exercise and sport sciences reviews.

Standing time and daily proportion of sedentary time are associated with pain-related disability in a one month accelerometer measurement in adults with overweight or obesity

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2021, Scandinavian journal of pain.

Sympathetic limitation of exercise hyperemia: even hypoperfused muscle is not exempted

D. Duncker, I. Heinonen, 2012, Front. Physio..

Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a pet study with nitric oxide and cyclooxygenase inhibition.

Y. Hellsten, B. Saltin, H. Sipilä, 2011, American journal of physiology. Heart and circulatory physiology.

Organ-specific physiological responses to acute physical exercise and long-term training in humans.

J. Knuuti, J. Hannukainen, P. Nuutila, 2014, Physiology.

Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort

M. Laakso, P. Iozzo, L. Nummenmaa, 2021, Diabetes Care.

Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2022, Scandinavian journal of medicine & science in sports.

The Regulation of Skeletal and Cardiac Muscle Blood Flow in Humans. Studies by positron emission tomography with special reference to exercise, adenosine and nitric oxide

I. Heinonen, 2010 .

perfusion heterogeneity exercise on human skeletal muscle perfusion and Comparison of exogenous adenosine and voluntary

V. Oikonen, J. Knuuti, J. Hannukainen, 2015 .

Comparison of exogenous adenosine and voluntary exercise on human skeletal muscle perfusion and perfusion heterogeneity.

Y. Hellsten, V. Oikonen, J. Knuuti, 2010, Journal of applied physiology.

Acute exercise mobilizes CD8+ cytotoxic T cells and NK cells in lymphoma patients

H. Minn, C. Sundberg, I. Heinonen, 2023, Frontiers in Physiology.

α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction.

V. Hruby, A. Saraste, M. Cai, 2013, Cardiovascular research.

Sprint interval training decreases left-ventricular glucose uptake compared to moderate-intensity continuous training in subjects with type 2 diabetes or prediabetes

J. Knuuti, J. Hannukainen, E. Löyttyniemi, 2017, Scientific Reports.

Changes in Quadriceps Femoris Muscle Perfusion Following Different Degrees of Cold-Water Immersion.

D. Low, V. Di Salvo, M. Weston, 2020, Journal of applied physiology.

Long-term Leisure-time Physical Activity and Serum Metabolome

P. O’Reilly, P. Elliott, T. Lehtimäki, 2013, Circulation.

Cardiac autonomic function and high-intensity interval training in middle-age men.

Antti M Kiviniemi, Heikki V Huikuri, H. Huikuri, 2014, Medicine and science in sports and exercise.

Left ventricular vascular and metabolic adaptations to high‐intensity interval and moderate intensity continuous training: a randomized trial in healthy middle‐aged men

J. Knuuti, J. Hannukainen, J. Pärkkä, 2016, The Journal of physiology.

Dynamic heterogeneity of exercising muscle blood flow and O2 utilization.

D. Poole, H. Rossiter, I. Heinonen, 2014, Medicine and science in sports and exercise.

Sedentary behaviours and obesity in adults: the Cardiovascular Risk in Young Finns Study

T. Lehtimäki, J. Viikari, O. Raitakari, 2013, BMJ Open.

Autonomic Function Predicts Fitness Response to Short-Term High-Intensity Interval Training

M. Tulppo, J. Hannukainen, A. Kiviniemi, 2015, International Journal of Sports Medicine.

VO(2peak), myocardial hypertrophy, and myocardial blood flow in endurance-trained men.

J. Knuuti, M. Laaksonen, M. Luotolahti, 2014, Medicine and science in sports and exercise.

Positron emission tomography detects greater blood flow and less blood flow heterogeneity in the exercising skeletal muscles of old compared with young men during fatiguing contractions

T. Rudroff, K. Kaskinoro, M. Bucci, 2014, The Journal of physiology.

A New Method to Improve Running Economy and Maximal Aerobic Power in Athletes: Endurance Training With Periodic Carbon Monoxide Inhalation

I. Heinonen, Peng Zhang, Yang Xiang, 2019, Front. Physiol..

Effects of Different Exercise Training Protocols on Gene Expression of Rac1 and PAK1 in Healthy Rat Fast- and Slow-Type Muscles

J. Rantala, J. Hannukainen, R. Mäkelä, 2020, Frontiers in Physiology.

Myocardial blood flow and its transit time, oxygen utilization, and efficiency of highly endurance-trained human heart

H. Sipilä, V. Oikonen, J. Knuuti, 2014, Basic Research in Cardiology.

Reducing Sedentary Time and Whole-Body Insulin Sensitivity in Metabolic Syndrome: A 6-Month Randomized Controlled Trial

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2022, Medicine and science in sports and exercise.

Standing is associated with insulin sensitivity in adults with metabolic syndrome.

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2021, Journal of science and medicine in sport.

Inhibition of α-adrenergic tone disturbs the distribution of blood flow in the exercising human limb.

M. Scheinin, J. Knuuti, K. Kaskinoro, 2013, American journal of physiology. Heart and circulatory physiology.

The effects of equal caloric high fat and western diet on metabolic syndrome, oxidative stress and vascular endothelial function in mice

E. Savontaus, S. Ruohonen, M. Ahotupa, 2014, Acta physiologica.

Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition

N. Owen, D. Dunstan, E. Cerin, 2019, British Journal of Sports Medicine.

Distinct effects of acute exercise and breaks in sitting on cognition in older adults : a randomised crossover trial

Owen, D. Dunstan, E. Cerin, 2019 .

The effect of acute exercise with increasing workloads on inactive muscle blood flow and its heterogeneity in humans

J. Knuuti, K. Kalliokoski, D. Duncker, 2012, European Journal of Applied Physiology.

Morning exercise mitigates the impact of prolonged sitting on cerebral blood flow in older adults.

D. Dunstan, E. Cerin, K. Ellis, 2019, Journal of applied physiology.

Myocardial Blood Flow and Metabolic Rate of Oxygen Measurement in the Right and Left Ventricles at Rest and During Exercise Using 15O-Labeled Compounds and PET

H. Sipilä, V. Oikonen, J. Knuuti, 2019, Front. Physiol..

Increasing Exercise Intensity Reduces Heterogeneity of Glucose Uptake in Human Skeletal Muscles

Juhani Knuuti, Sergey V. Nesterov, Jukka Kemppainen, 2012, PloS one.

Perfusion heterogeneity does not explain excess muscle oxygen uptake during variable intensity exercise

H. Kyröläinen, J. Knuuti, M. Laaksonen, 2010, Clinical physiology and functional imaging.

The effect of nitric oxide synthase inhibition with and without inhibition of prostaglandins on blood flow in different human skeletal muscles

Y. Hellsten, B. Saltin, K. Kalliokoski, 2017, European Journal of Applied Physiology.

Body Adiposity, But Not Elements of Objectively Measured Sedentary Behavior or Physical Activity, Is Associated With Circulating Liver Enzymes in Adults With Overweight and Obesity

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2021, Frontiers in Endocrinology.

The Effect of a Consumer-Based Activity Tracker Intervention on Accelerometer-Measured Sedentary Time Among Retirees: A Randomized Controlled REACT Trial

S. Stenholm, J. Vahtera, J. Pentti, 2021, The journals of gerontology. Series A, Biological sciences and medical sciences.

The Effect of Consumer-based Activity Tracker Intervention on Physical Activity among Recent Retirees—An RCT Study

S. Stenholm, J. Vahtera, J. Pentti, 2021, Medicine and science in sports and exercise.

Intramyocellular lipid accumulation after sprint interval and moderate‐intensity continuous training in healthy and diabetic subjects

J. Hannukainen, E. Löyttyniemi, K. Kalliokoski, 2019, Physiological reports.

The effect of acute exercise on circulating immune cells in newly diagnosed breast cancer patients

H. Minn, C. Sundberg, I. Heinonen, 2023, Scientific reports.

Muscle-specific glucose and free fatty acid uptake after sprint interval and moderate-intensity training in healthy middle-aged men.

J. Hannukainen, E. Löyttyniemi, K. Kalliokoski, 2015, Journal of applied physiology.

Effects of reduced sedentary time on cardiometabolic health in adults with metabolic syndrome: A three-month randomized controlled trial.

T. Vasankari, J. Knuuti, H. Vähä-Ypyä, 2022, Journal of science and medicine in sport.

Circulating N-terminal brain natriuretic peptide and cardiac function in response to acute systemic hypoxia in healthy humans

J. Knuuti, O. Vuolteenaho, A. Saraste, 2014, Journal of Translational Medicine.

Myocardial blood flow and adenosine A2A receptor density in endurance athletes and untrained men

S. Nesterov, K. Någren, V. Oikonen, 2008, The Journal of physiology.

Convergent Validity of a Physical Activity Questionnaire against Objectively Measured Physical Activity in Adults: The Cardiovascular Risk in Young Finns Study

J. Viikari, O. Raitakari, M. Hirvensalo, 2017 .

Muscle‐specific functional sympatholysis in humans

I. Heinonen, 2014, Experimental physiology.

Pulmonary blood flow and its distribution in highly trained endurance athletes and healthy control subjects.

V. Oikonen, J. Knuuti, J. Kemppainen, 2013, Journal of applied physiology.

Regulation of subcutaneous adipose tissue blood flow during exercise in humans.

J. Knuuti, R. Boushel, P. Nuutila, 2012, Journal of applied physiology.

[18F]FDG Accumulation in Early Coronary Atherosclerotic Lesions in Pigs

J. Knuuti, M. Teräs, A. Saraste, 2015, PloS one.

Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men.

J. Hannukainen, E. Löyttyniemi, K. Kalliokoski, 2016, American Journal of Physiology. Heart and Circulatory Physiology.

Different Predictors of Right and Left Ventricular Metabolism in Healthy Middle-Aged Men

J. Hannukainen, J. Pärkkä, E. Löyttyniemi, 2015, Front. Physiol..

Positron emission tomography detects greater blood flow and less blood flow heterogeneity in the exercising skeletal muscles of old compared with young men during fatiguing contractions

T. Rudroff, K. Kaskinoro, M. Bucci, 2014, The Journal of physiology.

Changes in Quadriceps Femoris Muscle Perfusion Following Different Degrees of Cold-Water Immersion Changes in Quadriceps Femoris Muscle Perfusion Following Different Degrees of Cold-Water Immersion. Journal of Applied

J. Kemppainen, K. Kalliokoski, A. Kirjavainen, 2021 .

Comfortable at just below your critical speed: how is blood flow distribution coupled to muscle fibre recruitment during exercise?

I. Heinonen, 2011, The Journal of physiology.

Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome – a six-month exploratory RCT

T. Vasankari, H. Vähä-Ypyä, E. Löyttyniemi, 2024, Journal of human hypertension.

Exercise training and physical activity in children: Hard interval training or low hanging fruits to ensure normal growth and maturation for the sake of lifelong physical activity?

I. Heinonen, 2023, Scandinavian journal of medicine & science in sports.