F. Carta

发表

Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV.

C. Supuran, A. Scozzafava, D. Vullo, 2013, Bioorganic & medicinal chemistry.

6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells.

C. Supuran, C. Ghelardini, L. di Cesare Mannelli, 2015, Journal of medicinal chemistry.

The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy

C. Supuran, A. Laurenzana, F. Bianchini, 2018, Journal of enzyme inhibition and medicinal chemistry.

Searching for intermediates in Prins cyclisations: the 2-oxa-5-adamantyl carbocation.

C. Reed, C. Willis, F. Carta, 2010, Organic & biomolecular chemistry.

Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore.

C. Supuran, A. Brancale, A. Dessì, 2011, Bioorganic & medicinal chemistry letters.

Lansoprazole and carbonic anhydrase IX inhibitors sinergize against human melanoma cells

C. Supuran, E. Iessi, S. Fais, 2016, Journal of enzyme inhibition and medicinal chemistry.

Chagas Disease: Perspectives on the Past and Present and Challenges in Drug Discovery

C. Supuran, A. Angeli, Alane Beatriz Vermelho, 2020, Molecules.

Natural extracellular nanovesicles and photodynamic molecules: is there a future for drug delivery?

C. Supuran, H. Murata, E. Iessi, 2017, Journal of enzyme inhibition and medicinal chemistry.

Amine- and Amino Acid-Based Compounds as Carbonic Anhydrase Activators

S. Carradori, C. Supuran, A. Angeli, 2021, Molecules.

Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs

C. Supuran, V. Kairys, M. Parikka, 2019, International journal of molecular sciences.

Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.

C. Supuran, A. Scozzafava, D. Vullo, 2009, Bioorganic & medicinal chemistry.

Development of a New LC-MS/MS Screening Method for Detection of 120 NPS and 43 Drugs in Blood

C. Supuran, F. Carta, E. Bertol, 2021, Separations.

Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity.

C. Supuran, A. Azqueta, A. Angeli, 2020, Journal of medicinal chemistry.

Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII)

C. Supuran, H. Abdel‐Aziz, A. Alafeefy, 2015, Journal of enzyme inhibition and medicinal chemistry.

Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells

E. Giannoni, C. Supuran, A. Scozzafava, 2013, Cell cycle.

Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts.

C. Supuran, A. Scozzafava, B. Telfer, 2012, Journal of medicinal chemistry.

Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.

C. Supuran, A. Scozzafava, J. Winum, 2012, Bioorganic & medicinal chemistry letters.

Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides.

C. Supuran, F. Carta, B. Mahon, 2017, European journal of medicinal chemistry.

Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.

C. Supuran, A. Scozzafava, M. Flentje, 2013, Bioorganic & medicinal chemistry.

Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis

C. Supuran, F. Bianchini, Jessica Ruzzolini, 2017, Journal of Molecular Medicine.

Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase

S. Carradori, C. Supuran, J. Winum, 2021, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of N'-phenyl-N-hydroxyureas and investigation of their inhibitory activities on human carbonic anhydrases.

C. Supuran, Z. Alothman, A. Angeli, 2018, Bioorganic chemistry.

Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.

C. Supuran, D. Vullo, A. Alafeefy, 2017, Bioorganic & medicinal chemistry.

Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma.

Abdul-Malek S. Al-Tamimi, C. Supuran, A. Alafeefy, 2016, Bioorganic & medicinal chemistry.

Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties.

Abdul-Malek S. Al-Tamimi, C. Supuran, A. Alafeefy, 2016, Bioorganic & medicinal chemistry.

New natural product carbonic anhydrase inhibitors incorporating phenol moieties.

C. Supuran, A. Karioti, A. Bilia, 2015, Bioorganic & medicinal chemistry.

Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action.

C. Supuran, A. Scozzafava, E. Masini, 2015, Bioorganic & medicinal chemistry.

Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII.

C. Supuran, G. Bartolucci, F. Carta, 2015, Bioorganic & medicinal chemistry.

Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity.

Abdul-Malek S. Al-Tamimi, C. Supuran, A. Scozzafava, 2015, Bioorganic & medicinal chemistry.

Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII.

C. Supuran, A. Scozzafava, F. Carta, 2012, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of selective hCA IX inhibitors

D. Vullo, A. Angeli, F. Carta, 2021 .

Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013)

C. Supuran, F. Carta, 2013, Expert opinion on therapeutic patents.

Assembled comprising an absorber of light in the near infrared covalently bound to a carbonic anhydrase inhibitor

C. Supuran, A. Scozzafava, S. Capaccioli, 2013 .

Selective inhibition of CA IX over CA XII in breast cancer cells using benzene sulfonamides: Disconnect between CA activity and growth inhibition

C. Supuran, C. Tu, F. Carta, 2018, bioRxiv.

Resolution of co-eluting isomers of anti-inflammatory drugs conjugated to carbonic anhydrase inhibitors from plasma in liquid chromatography by energy-resolved tandem mass spectrometry

C. Supuran, D. Vullo, C. Ghelardini, 2018, Journal of enzyme inhibition and medicinal chemistry.

Crystal Structure of a Tetrameric Type II β-Carbonic Anhydrase from the Pathogenic Bacterium Burkholderia pseudomallei

C. Supuran, M. Ferraroni, C. Capasso, 2020, Molecules.

X-ray crystallography of Epacadostat in adduct with Carbonic Anhydrase IX.

C. Supuran, T. Peat, A. Angeli, 2020, Bioorganic chemistry.

Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity.

C. Supuran, T. Peat, C. Ghelardini, 2019, European journal of medicinal chemistry.

Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects.

C. Supuran, T. Peat, C. Ghelardini, 2019, European journal of medicinal chemistry.

Mechanisms of action of carbonic anhydrase inhibitors

D. Vullo, F. Carta, 2019, Carbonic Anhydrases.

A deadly spillover: SARS-CoV-2 outbreak

C. Supuran, M. Mori, C. Capasso, 2020, Expert opinion on therapeutic patents.

Poly(amidoamine) Dendrimers with Carbonic Anhydrase Inhibitory Activity and Antiglaucoma Action.

C. Supuran, E. Masini, J. Winum, 2015, Journal of medicinal chemistry.

Dendrimers incorporating benzenesulfonamide moieties strongly inhibit carbonic anhydrase isoforms I-XIV.

C. Supuran, D. Vullo, Z. Alothman, 2015, Organic & biomolecular chemistry.

Poly(amidoamine) dendrimers show carbonic anhydrase inhibitory activity against α-, β-, γ- and η-class enzymes.

C. Supuran, D. Vullo, C. Capasso, 2015, Bioorganic & medicinal chemistry.

6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA.

C. Supuran, A. Scozzafava, F. Carta, 2015, Organic & biomolecular chemistry.

7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.

C. Supuran, A. Scozzafava, F. Carta, 2013, Bioorganic & medicinal chemistry.

Polypharmacology of epacadostat: a potent and selective inhibitor of the tumor associated carbonic anhydrases IX and XII.

C. Supuran, M. Ferraroni, A. Angeli, 2019, Chemical communications.

Acyl selenoureido benzensulfonamides show potent inhibitory activity against carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.

C. Supuran, C. Capasso, G. Abbas, 2017, Bioorganic chemistry.

Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis.

C. Supuran, D. Vullo, C. Ghelardini, 2019, Journal of medicinal chemistry.

Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111.

C. Supuran, F. Carta, B. Mahon, 2016, Bioorganic & medicinal chemistry.

Peptidomimetics as protein arginine deiminase 4 (PAD4) inhibitors

C. Supuran, A. Scozzafava, F. Carta, 2015, Journal of enzyme inhibition and medicinal chemistry.

Taurultams incorporating arylsulfonamide: First in vitro inhibition studies of α-, β- and γ-class Carbonic Anhydrases from Vibrio cholerae and Burkholderia pseudomallei.

C. Supuran, C. Capasso, A. Angeli, 2021, European journal of medicinal chemistry.

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX.

C. Supuran, A. Innocenti, B. Spingler, 2012, Angewandte Chemie.

Small Molecule Alkoxy Oriented Selectiveness on Human Carbonic Anhydrase II and IX Inhibition

C. Supuran, A. Angeli, F. Carta, 2022, ChemMedChem.

In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos

C. Supuran, D. Vullo, M. Parikka, 2019, Journal of enzyme inhibition and medicinal chemistry.

Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis.

C. Supuran, A. Scozzafava, D. Vullo, 2017, Journal of medicinal chemistry.

Multivalent Carbonic Anhydrases Inhibitors †

C. Supuran, J. Winum, P. Dumy, 2019, International journal of molecular sciences.

CO2 Permeability of Rat Hepatocytes and Relation of CO2 Permeability to CO2 Production

Q. Yuan, C. Supuran, V. Endeward, 2018, Cellular Physiology and Biochemistry.

CO2 and HCO3- Permeability of the Rat Liver Mitochondrial Membrane

C. Supuran, V. Endeward, G. Gros, 2016, Cellular Physiology and Biochemistry.

Carbonic anhydrase inhibition for the management of cerebral ischemia: in vivo evaluation of sulfonamide and coumarin inhibitors

C. Supuran, C. Ghelardini, L. Micheli, 2016, Journal of enzyme inhibition and medicinal chemistry.

Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

F. Sbrana, C. Supuran, S. Avnet, 2015, Expert opinion on therapeutic targets.

Dithiocarbamates are strong inhibitors of the beta-class fungal carbonic anhydrases from Cryptococcus neoformans, Candida albicans and Candida glabrata.

C. Supuran, A. Scozzafava, S. M. Monti, 2012, Bioorganic & medicinal chemistry letters.

Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.

C. Supuran, A. Scozzafava, A. Innocenti, 2011, Bioorganic & medicinal chemistry letters.

Thiosemicarbazide-Substituted Coumarins as Selective Inhibitors of the Tumor Associated Human Carbonic Anhydrases IX and XII

C. Supuran, A. Angeli, F. Carta, 2022, Molecules.

Benzenesulfonamides with different rigidity-conferring linkers as carbonic anhydrase inhibitors: an insight into the antiproliferative effect on glioblastoma, pancreatic, and breast cancer cells

S. Carradori, C. Supuran, R. Ronca, 2022, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties

C. Supuran, D. Vullo, F. Carta, 2021, Pharmaceuticals.

Tellurides bearing benzensulfonamide as carbonic anhydrase inhibitors with potent antitumor activity.

C. Supuran, C. Ghelardini, M. Pinteala, 2021, Bioorganic & medicinal chemistry letters.

Seleno Containing Compounds as Potent and Selective Antifungal Agents

C. Supuran, C. Capasso, A. Angeli, 2022, ACS infectious diseases.

Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents.

C. Supuran, A. Scozzafava, E. Masini, 2014, Bioorganic & medicinal chemistry.

Structural modulation of the biological activity of gold nanoparticles functionalized with a carbonic anhydrase inhibitor

P. Baglioni, C. Supuran, A. Scozzafava, 2013, The European physical journal. E, Soft matter.

Selected strategies to fight pathogenic bacteria

C. Supuran, J. Yli-Kauhaluoma, A. Sobolev, 2023, Journal of enzyme inhibition and medicinal chemistry.

Spirocyclic sulfonamides with carbonic anhydrase inhibitory and anti-neuropathic pain activity.

Abdul-Malek S. Al-Tamimi, C. Supuran, C. Ghelardini, 2019, Bioorganic chemistry.

Novel Insights on CAI-CORM Hybrids: Evaluation of the CO Releasing Properties and Pain-Relieving Activity of Differently Substituted Coumarins for the Treatment of Rheumatoid Arthritis.

S. Carradori, C. Supuran, C. Ghelardini, 2023, Journal of medicinal chemistry.

Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis

C. Supuran, E. Masini, F. Carta, 2020, Biomolecules.

Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo.

C. Supuran, A. Scozzafava, E. Masini, 2012, Journal of medicinal chemistry.

Design and Synthesis of Novel Indole β-Diketo Acid Derivatives as HIV-1 Integrase Inhibitors

R. Shoemaker, R. Dayam, N. Neamati, 2004 .

N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII.

C. Supuran, D. Vullo, A. Kazaks, 2017, Bioorganic & medicinal chemistry.

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

S. Carradori, C. Supuran, S. Dedhar, 2020, Metabolites.

Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa.

C. Supuran, D. Vullo, C. Capasso, 2017, Bioorganic & medicinal chemistry.

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

S. Leung, A. Oloumi, B. Clarke, 2011, Cancer Research.

Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.

C. Supuran, A. Scozzafava, S. Dedhar, 2011, Journal of medicinal chemistry.

Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations.

C. Supuran, E. Masini, M. Ferraroni, 2016, Journal of medicinal chemistry.

7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII

C. Supuran, F. Carta, A. Nocentini, 2016, Journal of enzyme inhibition and medicinal chemistry.

Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis

C. Supuran, D. Vullo, F. Carta, 2013, Journal of enzyme inhibition and medicinal chemistry.

Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases.

C. Supuran, A. Scozzafava, J. Winum, 2012, Chemical communications.

5- and 6-membered (thio)lactones are prodrug type carbonic anhydrase inhibitors.

C. Supuran, A. Scozzafava, F. Carta, 2012, Bioorganic & medicinal chemistry letters.

4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.

C. Supuran, M. Ferraroni, G. Rance, 2016, Journal of medicinal chemistry.

Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups.

C. Supuran, A. Scozzafava, E. Masini, 2014, Journal of medicinal chemistry.

Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.

C. Supuran, A. Scozzafava, M. Ferraroni, 2014, Bioorganic & medicinal chemistry.

Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases.

C. Supuran, A. Scozzafava, J. Winum, 2012, Chemical communications.

Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates

C. Supuran, D. Vullo, C. Capasso, 2017, Journal of enzyme inhibition and medicinal chemistry.

Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma.

E. Novellino, C. Supuran, A. Scozzafava, 2016, Journal of medicinal chemistry.

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases

U. Farooq, C. Supuran, G. Zanotti, 2020, International journal of molecular sciences.

Design of Novel Bioisosteres of β-Diketo Acid Inhibitors of HIV-1 Integrase

N. Neamati, A. Dessì, F. Carta, 2005 .

New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs.

P. Lambin, M. V. van Gisbergen, L. Dubois, 2017, European journal of medicinal chemistry.

Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms

C. Supuran, F. Allouche, F. Carta, 2013, Journal of enzyme inhibition and medicinal chemistry.

Structural investigation of 3,5-disubstituted isoxazoles by 1H-nuclear magnetic resonance†

N. Neamati, F. Carta, M. Sechi, 2003 .

Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors.

C. Supuran, T. Peat, C. Ghelardini, 2017, ACS medicinal chemistry letters.

Inhibition of carbonic anhydrase IX targets primary tumors, metastases, and cancer stem cells: Three for the price of one

C. Supuran, S. M. Monti, F. Carta, 2018, Medicinal research reviews.

Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.

C. Supuran, D. Vullo, A. Alafeefy, 2017, Bioorganic & medicinal chemistry.

Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies.

C. Supuran, A. Scozzafava, M. Ferraroni, 2016, Bioorganic & medicinal chemistry.

Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins.

C. Supuran, A. Scozzafava, M. Ferraroni, 2016, Journal of medicinal chemistry.

7-Amino-3,4-dihydro-1H-quinolin-2-one, a compound similar to the substituted coumarins, inhibits α-carbonic anhydrases without hydrolysis of the lactam ring

C. Supuran, D. Vullo, F. Carta, 2015, Journal of enzyme inhibition and medicinal chemistry.

New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.

C. Supuran, A. Scozzafava, D. Vullo, 2012, Bioorganic & medicinal chemistry letters.

Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations.

C. Supuran, A. Scozzafava, F. Carta, 2012, Chemical communications.

Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule.

K. Kaila, C. Supuran, A. Scozzafava, 2010, Journal of medicinal chemistry.

Phenols and Polyphenols as Carbonic Anhydrase Inhibitors

C. Supuran, A. Karioti, F. Carta, 2016, Molecules.

Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.

Vladimir Garaj, Andrea Scozzafava, Alfonso Maresca, 2011, Bioorganic & medicinal chemistry.

Direct and straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors.

C. Supuran, M. Ferraroni, A. Angeli, 2019, European journal of medicinal chemistry.

From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes.

C. Sotriffer, N. Neamati, A. Bacchi, 2008, Journal of medicinal chemistry.

Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo.

C. Supuran, A. Scozzafava, E. Masini, 2013, Journal of medicinal chemistry.

Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019

C. Supuran, F. Carta, A. S. Altamimi, 2019, Expert opinion on therapeutic patents.

Polyamines and α-Carbonic Anhydrases

C. Supuran, A. Scozzafava, F. Carta, 2016, Molecules.

Design and Synthesis of Novel Dihydroxyindole-2-Carboxylic Acids as HIV-1 Integrase Inhibitors

Roberto Dallocchio, Alberto Mariani, Fabrizio Carta, 2004, Antiviral chemistry & chemotherapy.

Antiobesity carbonic anhydrase inhibitors: a literature and patent review

Andrea Scozzafava, Fabrizio Carta, Claudiu T Supuran, 2013, Expert opinion on therapeutic patents.

Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors.

C. Supuran, A. Angeli, C. Matassini, 2020, ACS medicinal chemistry letters.

Synthesis of Azasugar–Sulfonamide conjugates and their Evaluation as Inhibitors of Carbonic Anhydrases: the Azasugar Approach to Selectivity

C. Supuran, M. Ferraroni, A. Angeli, 2021 .

A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects.

C. Supuran, A. Scozzafava, C. Ghelardini, 2015, Bioorganic & medicinal chemistry.

Discovery of new organoselenium compounds as antileishmanial agents.

Abdul-Malek S. Al-Tamimi, C. Supuran, A. Angeli, 2019, Bioorganic chemistry.

Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.

C. Supuran, A. Scozzafava, P. Tosco, 2013, Bioorganic & medicinal chemistry letters.

Azidothymidine “Clicked” into 1,2,3-Triazoles: First Report on Carbonic Anhydrase–Telomerase Dual-Hybrid Inhibitors

S. Carradori, C. Supuran, T. Peat, 2020, Journal of medicinal chemistry.

Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes.

N. Neamati, A. Dessì, F. Carta, 2009, Antiviral research.

Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors.

C. Supuran, A. Angeli, G. Bartolucci, 2017, Bioorganic & medicinal chemistry.

Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action.

H. Buschmann, C. Supuran, W. Schwab, 2017, Journal of medicinal chemistry.

Carbonic anhydrase inhibitors for the treatment of epilepsy and obesity

F. Carta, Emanuela Berrino, 2019, Carbonic Anhydrases.

Sulfonamides: a patent review (2008 – 2012)

C. Supuran, A. Scozzafava, F. Carta, 2012, Expert opinion on therapeutic patents.

Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.

R. Pecori, C. Supuran, E. Masini, 2018, Journal of medicinal chemistry.

State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes.

C. Supuran, D. Vullo, F. Carta, 2019, Current medicinal chemistry.

Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition

C. Supuran, K. Brown, C. Tu, 2018, PloS one.

Selective inhibition of CA IX over CA XII in breast cancer cells using benzene sulfonamides: Disconnect between CA activity and growth inhibition

C. Supuran, K. Brown, C. Tu, 2018, bioRxiv.

In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition

C. Supuran, A. Salatino, F. Trapasso, 2020, Antioxidants.

In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition

C. Supuran, A. Salatino, F. Trapasso, 2020 .

Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties.

C. Supuran, F. Carta, M. Tanc, 2014, Bioorganic & medicinal chemistry.

Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety.

C. Supuran, F. Carta, M. Tanc, 2013, Bioorganic & medicinal chemistry.

Antiglaucoma carbonic anhydrase inhibitors: a patent review

C. Supuran, A. Scozzafava, E. Masini, 2013, Expert opinion on therapeutic patents.

Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors

S. C. Chafe, Frederick S. Vizeacoumar, Franco J. Vizeacoumar, 2021, Science advances.

First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors

C. Supuran, D. Vullo, A. Papini, 2022, Journal of enzyme inhibition and medicinal chemistry.

Pharmacological inhibition of Carbonic Anhydrase IX and XII to enhance targeting of acute myeloid leukaemia cells under hypoxic conditions

C. Supuran, G. Sandusky, M. Czader, 2021, Journal of cellular and molecular medicine.

Modulating the Efficacy of Carbonic Anhydrase Inhibitors through Fluorine Substitution.

C. Supuran, F. Carta, A. Martin-Mingot, 2021, Angewandte Chemie.

Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

C. Supuran, C. Capasso, S. Parkkila, 2020, Journal of enzyme inhibition and medicinal chemistry.

Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal Arteries

C. Supuran, F. Carta, S. Selleri, 2019, International Journal of Molecular Sciences.

Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors

C. Supuran, M. Botta, A. Mugelli, 2017, Molecules.

Heterologous expression and biochemical characterisation of the recombinant β-carbonic anhydrase (MpaCA) from the warm-blooded vertebrate pathogen malassezia pachydermatis

A. Scaloni, C. Supuran, V. De Luca, 2021, Journal of enzyme inhibition and medicinal chemistry.

Inhibitory Effects of Sulfonamide Derivatives on the β-Carbonic Anhydrase (MpaCA) from Malassezia pachydermatis, a Commensal, Pathogenic Fungus Present in Domestic Animals

A. Scaloni, C. Supuran, V. De Luca, 2021, International journal of molecular sciences.

N-aryl-N'-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties.

C. Supuran, J. Winum, C. Ghelardini, 2019, Bioorganic chemistry.

Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides

C. Supuran, A. Angeli, F. Carta, 2017, Journal of enzyme inhibition and medicinal chemistry.

One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes.

C. Supuran, E. Masini, M. Ferraroni, 2021, Journal of medicinal chemistry.

Carbonic anhydrases and their functional differences in human and mouse sperm physiology.

C. Supuran, J. Deitmer, F. Carta, 2015, Biochemical and biophysical research communications.

The role of carbonic anhydrases in extinction of contextual fear memory

I. Izquierdo, C. Supuran, P. Blandina, 2020, Proceedings of the National Academy of Sciences.

Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies.

C. Supuran, F. Carta, A. Nocentini, 2018, Chemistry.

Carbonic anhydrase activation enhances object recognition memory in mice through phosphorylation of the extracellular signal-regulated kinase in the cortex and the hippocampus

C. Supuran, A. Scozzafava, D. Vullo, 2017, Neuropharmacology.

Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry.

C. Supuran, F. Carta, R. McKenna, 2014, ACS medicinal chemistry letters.

Development of Praziquantel sulphonamide derivatives as antischistosomal drugs

J. Keiser, C. Supuran, M. Ferraroni, 2022, Journal of enzyme inhibition and medicinal chemistry.

Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides.

C. Supuran, M. Ferraroni, M. Pinteala, 2021, Journal of medicinal chemistry.

Dithiocarbamates with potent inhibitory activity against the Saccharomyces cerevisiae β-carbonic anhydrase

C. Supuran, A. Scozzafava, D. Vullo, 2016, Journal of Enzyme Inhibition and Medicinal Chemistry.

Sulfonamides and their isosters as carbonic anhydrase inhibitors.

C. Supuran, A. Scozzafava, F. Carta, 2014, Future medicinal chemistry.

A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer

C. Supuran, A. Laurenzana, F. Bianchini, 2019, Journal of enzyme inhibition and medicinal chemistry.

Vasodilation of Pre-contracted Porcine Retinal Arteries by Carbonic Anhydrase Inhibitors with Enhanced Lipophilicity

C. Supuran, A. Angeli, F. Carta, 2022, Current eye research.

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer’s Disease

C. Supuran, S. Fossati, F. Carta, 2019, International journal of molecular sciences.

Dual Acting Carbon Monoxide Releasing Molecules and Carbonic Anhydrase Inhibitors Differentially Modulate Inflammation in Human Tenocytes

S. Carradori, A. Cataldi, F. Oliva, 2021, Biomedicines.

Bioisosteric Development of Multi-target Nonsteroidal Anti-inflammatory Drug - Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.

C. Supuran, E. Masini, C. Ghelardini, 2020, Journal of Medicinal Chemistry.

Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.

C. Supuran, A. Scozzafava, D. Vullo, 2018, Journal of medicinal chemistry.

β-CA-specific inhibitor dithiocarbamate Fc14–584B: a novel antimycobacterial agent with potential to treat drug-resistant tuberculosis

C. Supuran, Harlan R. Barker, M. Parikka, 2017, Journal of enzyme inhibition and medicinal chemistry.

The anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies.

C. Supuran, J. Winum, F. Carta, 2016, Organic & biomolecular chemistry.

Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.

C. Supuran, J. Winum, K. D'Ambrosio, 2012, Journal of medicinal chemistry.

Synthesis, Computational Studies and Assessment of in Vitro Activity of Squalene Derivatives as Carbonic Anhydrase Inhibitors

C. Supuran, M. Pinteala, A. Angeli, 2020, ChemMedChem.

Mono- and di-thiocarbamate inhibition studies of the δ-carbonic anhydrase TweCAδ from the marine diatom Thalassiosira weissflogii

C. Supuran, C. Capasso, Silvia Bua, 2018, Journal of enzyme inhibition and medicinal chemistry.

Advances in new psychoactive substances identification: the U.R.I.To.N. Consortium

Claudiu T. Supuran, Elisabetta Bertol, Francesco Mari, 2017, Journal of enzyme inhibition and medicinal chemistry.

Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.

P. Lambin, L. Dubois, A. Harris, 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Secondary and tertiary sulfonamides: a patent review (2008 – 2012)

C. Supuran, A. Scozzafava, F. Carta, 2013, Expert opinion on therapeutic patents.

Novel therapies for glaucoma: a patent review 2007 – 2011

C. Supuran, A. Scozzafava, F. Carta, 2012, Expert opinion on therapeutic patents.

Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors.

S. Carradori, C. Supuran, S. Dedhar, 2020, Biophysical journal.

The β-carbonic anhydrases from Mycobacterium tuberculosis as drug targets.

C. Supuran, A. Scozzafava, I. Nishimori, 2010, Current pharmaceutical design.

Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.

C. Supuran, S. Mowbray, F. Carta, 2009, Bioorganic & medicinal chemistry letters.

Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium

C. Supuran, F. Annunziato, A. Laurenzana, 2016, Journal of enzyme inhibition and medicinal chemistry.

First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy

C. Supuran, M. Ferraroni, C. Ghelardini, 2023, Journal of medicinal chemistry.

Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae

C. Supuran, M. Seleem, Nader S. Abutaleb, 2021, Journal of enzyme inhibition and medicinal chemistry.

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes

C. Supuran, A. Mugelli, C. Capasso, 2018, Journal of enzyme inhibition and medicinal chemistry.

Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 beta-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides.

C. Supuran, A. Scozzafava, D. Vullo, 2009, Bioorganic & medicinal chemistry letters.

Benzylaminoethylureido‐Tailed Benzenesulfonamides Show Potent Inhibitory Activity against Bacterial Carbonic Anhydrases

U. Farooq, C. Supuran, C. Capasso, 2020, ChemMedChem.

Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.

Abdul-Malek S. Al-Tamimi, C. Supuran, M. Ferraroni, 2019, European journal of medicinal chemistry.

Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines.

C. Supuran, C. Ghelardini, A. Angeli, 2018, ACS medicinal chemistry letters.

Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition.

C. Supuran, A. Scozzafava, F. Carta, 2013, Bioorganic & medicinal chemistry.

A Class of 4-Sulfamoylphenyl-ω-aminoalkyl Ethers with Effective Carbonic Anhydrase Inhibitory Action and Antiglaucoma Effects

C. Supuran, A. Scozzafava, E. Masini, 2014, Journal of medicinal chemistry.

α-Carbonic Anhydrases Possess Thioesterase Activity.

C. Supuran, A. Scozzafava, F. Carta, 2015, ACS medicinal chemistry letters.

Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action

C. Supuran, Z. Alothman, F. Carta, 2017, Journal of enzyme inhibition and medicinal chemistry.

Unconventional amino acids in medicinal chemistry: First report on taurine merged within carbonic anhydrase inhibitors.

C. Supuran, D. Vullo, A. Angeli, 2020, Bioorganic chemistry.

Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster.

C. Supuran, M. Hilvo, D. Vullo, 2013, Bioorganic & medicinal chemistry.

Serendipitous fragment-based drug discovery: ketogenic diet metabolites and statins effectively inhibit several carbonic anhydrases.

C. Supuran, A. Scozzafava, D. Vullo, 2012, Chemical communications.

Modulating the Efficacy of Carbonic Anhydrase Inhibitors through Fluorine Substitution

C. Supuran, F. Carta, A. Martin-Mingot, 2021, Angewandte Chemie.

Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action.

S. Carradori, C. Supuran, M. Ferraroni, 2021, European journal of medicinal chemistry.

More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design

A. Milac, C. Supuran, F. Carta, 2013, Journal of enzyme inhibition and medicinal chemistry.

Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX.

C. Supuran, S. Dedhar, M. Ferraroni, 2018, Journal of medicinal chemistry.

Dual Carbonic Anhydrase IX/XII Inhibitors and Carbon Monoxide Releasing Molecules Modulate LPS-Mediated Inflammation in Mouse Macrophages

S. Carradori, C. Supuran, H. Schweikl, 2021, Antioxidants.

Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs.

C. Supuran, D. Vullo, Z. Alothman, 2017, Bioorganic & medicinal chemistry.

Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents.

Abdul-Malek S. Al-Tamimi, C. Supuran, R. Ahmad, 2016, European journal of medicinal chemistry.

Plasmonic Particles that Hit Hypoxic Cells

Francesca Tatini, Roberto Pini, Franco Fusi, 2015 .

Cyclodextrin complexation highly enhances efficacy of arylsulfonylureido benzenesulfonamide carbonic anhydrase inhibitors as a topical antiglaucoma agents.

C. Supuran, A. Scozzafava, E. Masini, 2015, Bioorganic & medicinal chemistry.

Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.

C. Supuran, M. Ferraroni, A. Veselovsky, 2021, Journal of medicinal chemistry.

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

C. Supuran, C. Ward, A. Turnbull, 2017, Oncotarget.

Oncotarget paper published

C. Supuran, C. Ward, A. Turnbull, 2017 .

Explorer Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

C. Supuran, C. Ward, A. Turnbull, 2017 .

N-aryl-N'-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions.

C. Supuran, T. Tuccinardi, A. Angeli, 2020, Bioorganic chemistry.

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

C. Supuran, G. Sandusky, M. Kelley, 2018, Scientific Reports.

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

C. Supuran, G. Sandusky, M. Kelley, 2018, Scientific Reports.

A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors.

C. Supuran, D. Vullo, Federica Moraca, 2019, European journal of medicinal chemistry.

Carbonic Anhydrases: Versatile and Useful Biocatalysts in Chemistry and Biochemistry

C. Supuran, A. Angeli, F. Carta, 2020, Catalysts.

Carbonic Anhydrase Inhibitors: Inhibition of Cytosolic Carbonic Anhydrase Isozymes II and VII with Simple Aromatic Sulfonamides and Some Azo Dyes

C. Supuran, M. Tiwari, F. Carta, 2009, Chemical biology & drug design.

Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain.

C. Supuran, C. Ghelardini, K. D'Ambrosio, 2021, European journal of medicinal chemistry.

Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models

M. Korc, M. Ivan, C. Supuran, 2016, Molecular Cancer Therapeutics.

A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells.

C. Supuran, K. Brown, C. Heldermon, 2019, The Biochemical journal.

Polypharmacology of Epacadostat: a Potent and Selective Inhibitor of the Tumor Associated Carbonic Anhydrases IX and XII

C. Supuran, M. Ferraroni, A. Angeli, 2019 .

Prostaglandins with Carboxylic Functionalities for the Treatment of Glaucoma

C. Supuran, F. Carta, 2016 .

Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.

M. Korc, M. Ivan, C. Supuran, 2016, Molecular cancer therapeutics.

Uncovering Novel Capsaicin Inhibitory Activity towards Human Carbonic Anhydrase Isoforms IX and XII by Combining In Silico and In Vitro Studies

C. Supuran, A. Salatino, F. Trapasso, 2023, Antioxidants.

Evaluation of Thio- and Seleno-Acetamides Bearing Benzenesulfonamide as Inhibitor of Carbonic Anhydrases from Different Pathogenic Bacteria

C. Supuran, C. Capasso, G. Abbas, 2020, International journal of molecular sciences.

Multiplexed cellular profiling identifies an organoselenium compound as an inhibitor of CRM1‐mediated nuclear export

C. Supuran, R. Silvestri, W. Link, 2022, Traffic.

Intramolecular oxidative deselenization of acylselenoureas: a facile synthesis of benzoxazole amides and carbonic anhydrase inhibitors.

C. Supuran, T. Peat, A. Angeli, 2016, Organic & biomolecular chemistry.

An innovative spectroscopic approach for qualitative and quantitative evaluation of Mb-CO from myoglobin carbonylation reaction through chemometrics methods

S. Carradori, C. Supuran, Alane Beatriz Vermelho, 2021, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.

Metalloenzyme inhibitors for the treatment of Gram-negative bacterial infections: a patent review (2009 – 2012)

C. Supuran, A. Scozzafava, F. Carta, 2013, Expert opinion on therapeutic patents.

Multitargeting application of proline-derived peptidomimetics addressing cancer-related human matrix metalloproteinase 9 and carbonic anhydrase II.

C. Supuran, A. Angeli, F. Carta, 2021, European journal of medicinal chemistry.

Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology.

C. Supuran, T. Peat, C. Ghelardini, 2018, ACS medicinal chemistry letters.

Selenolesterase enzyme activity of carbonic anhydrases.

C. Supuran, M. Ferraroni, A. Angeli, 2020, Chemical communications.

Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors.

C. Supuran, A. Angeli, F. Carta, 2020, European journal of medicinal chemistry.

The Integrase: An Overview of a Key Player Enzyme in the Antiviral Scenario

C. Supuran, F. Carta, Gioele Renzi, 2023, International journal of molecular sciences.

Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships

S. Carradori, C. Supuran, C. Capasso, 2023, Journal of enzyme inhibition and medicinal chemistry.

Escinosome thermosensitive gel optimizes efficacy of CAI-CORM in a rat model of rheumatoid arthritis.

C. Supuran, C. Ghelardini, L. Mannelli, 2023, Journal of controlled release : official journal of the Controlled Release Society.

A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells

C. Supuran, K. Brown, C. Heldermon, 2018, bioRxiv.

Oncotarget paper published

C. Supuran, C. Ward, A. Turnbull, 2017 .

New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors

C. Supuran, A. Angeli, F. Carta, 2023, Molecules.

Carbonic anhydrases and their functional differences in human and mouse sperm physiology.

C. Supuran, J. Deitmer, F. Carta, 2015, Biochemical and biophysical research communications.

Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013)

C. Supuran, F. Carta, 2013, Expert opinion on therapeutic patents.

Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster.

C. Supuran, M. Hilvo, D. Vullo, 2013, Bioorganic & medicinal chemistry.

Membrane Permeability Is Required for the Vasodilatory Effect of Carbonic Anhydrase Inhibitors in Porcine Retinal Arteries

C. Supuran, D. Vullo, F. Carta, 2023, International journal of molecular sciences.

Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on In Vitro and In Vivo Studies

C. Supuran, J. Winum, M. Parikka, 2018, Molecules.

Kinase inhibitors: 20 years of success and many new challenges and recent trends in their patents.

C. Supuran, F. Carta, H. Ghneim, 2024, Expert Opinion on Therapeutic Patents.

Erlotinib-containing benzenesulfonamides as anti-Helicobacter pylori agents through carbonic anhydrase inhibition.

C. Supuran, C. Capasso, R. Grande, 2023, Future medicinal chemistry.

Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy.

C. Supuran, M. Ferraroni, C. Capasso, 2024, Journal of medicinal chemistry.

Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis

C. Supuran, C. Ghelardini, Bergonzi, 2019, International journal of molecular sciences.

Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity.

C. Supuran, D. Vullo, A. Alafeefy, 2017, Bioorganic & medicinal chemistry.

Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors.

C. Supuran, A. Scozzafava, D. Vullo, 2016, Bioorganic & medicinal chemistry.

Carbonic anhydrase, its inhibitors and vascular function

C. Supuran, F. Carta, T. Eysteinsson, 2024, Frontiers in molecular biosciences.