D. Ragsdale

发表

Direct demonstration of persistent Na+ channel activity in dendritic processes of mammalian cortical neurones

A. Alonso, J. Magistretti, D. Ragsdale, 1999, The Journal of physiology.

A mutation in segment IVS6 disrupts fast inactivation of sodium channels.

T. Scheuer, W. Catterall, D. Ragsdale, 1994, Proceedings of the National Academy of Sciences of the United States of America.

The intracellular segment of the sodium channel β1 subunit is required for its efficient association with the channel α subunit

J. Malhotra, D. Ragsdale, L. Isom, 2001 .

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.

W. Catterall, T. Scheuer, W. Catterall, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Tenascin-R Is a Functional Modulator of Sodium Channel β Subunits*

M. Schachner, J. Malhotra, D. Ragsdale, 1999, The Journal of Biological Chemistry.

Cloning, Localization, and Functional Expression of Sodium Channel β1A Subunits*

M. D'Andrea, D. Ragsdale, L. Isom, 2000, The Journal of Biological Chemistry.

Molecular Determinants of Na+ Channel Function in the Extracellular Domain of the β1 Subunit*

W. Catterall, David K. Smith, T. Scheuer, 1998, The Journal of Biological Chemistry.

Expressional potency of mRNAs encoding receptors and voltage-activated channels in the postmortem rat brain.

R. Miledi, D. Ragsdale, Ricardo Miledi, 1991, Proceedings of the National Academy of Sciences of the United States of America.

NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-Benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A New Selective Inhibitor of T-Type Calcium Channels

H. Zhuang, Luping Z. Huang, D. Ragsdale, 2004, Journal of Pharmacology and Experimental Therapeutics.

Molecular determinants of state-dependent block of Na+ channels by local anesthetics.

W. Catterall, T. Scheuer, W. Catterall, 1994, Science.

The batrachotoxin receptor on the voltage-gated sodium channel is guarded by the channel activation gate.

D. Ragsdale, Hong-ling Li, David Hadid, 2002, Molecular pharmacology.

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

Massimo Mantegazza, Giuseppe Biagini, Massimo Avoli, 2010, The Lancet Neurology.

Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif

W. Catterall, T. Scheuer, R. Westenbroek, 1995, Cell.

Expression of Neurotransmitter Receptors by mRNAs from Neurons Developing In Vitro: A Xenopus Oocyte Expression Study

R. Miledi, A. Schousboe, P. Wahl, 1993, Journal of neurochemistry.

State‐dependent access to the batrachotoxin receptor on the sodium channel

D. Ragsdale, Lyn De Leon, 2003, Neuroreport.

Functional characterization of the D188V mutation in neuronal voltage-gated sodium channel causing generalized epilepsy with febrile seizures plus (GEFS)

G. Rouleau, D. Rochefort, R. Lafreniére, 2003, Epilepsy Research.

Sodium channels as molecular targets for antiepileptic drugs

M. Avoli, D. Ragsdale, 1998, Brain Research Reviews.

A Critical Role for the S4-S5 Intracellular Loop in Domain IV of the Sodium Channel α-Subunit in Fast Inactivation*

W. Catterall, T. Scheuer, D. Ragsdale, 1998, The Journal of Biological Chemistry.

A Critical Role for Transmembrane Segment IVS6 of the Sodium Channel α Subunit in Fast Inactivation (*)

W. Catterall, T. Scheuer, D. Ragsdale, 1995, The Journal of Biological Chemistry.

Functional Co-expression of the 1 and Type IIA Subunits of Sodium Channels in a Mammalian Cell Line (*)

W. Catterall, T. Scheuer, D. Ragsdale, 1995, The Journal of Biological Chemistry.

How do mutant Nav1.1 sodium channels cause epilepsy?

D. Ragsdale, 2008, Brain Research Reviews.

An epilepsy mutation in the β1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin

D. Ragsdale, L. Meadows, Paul T. Lucas, 2005, Epilepsy Research.

Functional and Biochemical Analysis of a Sodium Channel β1 Subunit Mutation Responsible for Generalized Epilepsy with Febrile Seizures Plus Type 1

J. Malhotra, D. Ragsdale, L. Isom, 2002, The Journal of Neuroscience.

A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel.

D. Ragsdale, D S Ragsdale, H L Li, 1999, Molecular pharmacology.

Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs.

W. Catterall, T. Scheuer, W. Catterall, 1991, Molecular pharmacology.

Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line.

T. Scheuer, W. Catterall, D. Ragsdale, 1995, The Journal of biological chemistry.

Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C

P. Séguéla, D. Ragsdale, D. O'donnell, 2011, Molecular pain.

Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary β1, β2 and β3 subunits

Y. H. Chen, D. Ragsdale, J. Clare, 2002, Neuroscience.

Functional modulation of human brain Nav1.3 sodium channels, expressed in mammalian cells, by auxiliary beta 1, beta 2 and beta 3 subunits.

Y. H. Chen, D. Ragsdale, J. Clare, 2002, Neuroscience.

Evolving Mechanistic Concepts of Epileptiform Synchronization and their Relevance in Curing Focal Epileptic Disorders

M. Avoli, M. Lévesque, D. Ragsdale, 2019, Current neuropharmacology.

Lacosamide modulates interictal spiking and high-frequency oscillations in a model of mesial temporal lobe epilepsy

M. Avoli, M. Lévesque, D. Ragsdale, 2015, Epilepsy Research.

Increased Persistent Sodium Currents in Rat Entorhinal Cortex Layer V Neurons in a Post–Status Epilepticus Model of Temporal Lobe Epilepsy

A. Alonso, D. Ragsdale, Newton Agrawal, 2003, Epilepsia.

Reduced GABAB receptor subunit expression and paired-pulse depression in a genetic model of absence seizures

M. Avoli, G. D’Arcangelo, V. Tancredi, 2007, Neurobiology of Disease.

Activity-dependent changes in excitability of perirhinal cortex networks in vitro

M. Avoli, M. D'antuono, G. Biagini, 2015, Pflügers Archiv: European Journal of Physiology.

Proepileptic Influence of a Focal Vascular Lesion Affecting Entorhinal Cortex-CA3 Connections After Status Epilepticus

M. Avoli, G. Biagini, I. Zini, 2008, Journal of neuropathology and experimental neurology.

Persistent sodium channel activity mediates subthreshold membrane potential oscillations and low-threshold spikes in rat entorhinal cortex layer V neurons

A. Alonso, B. Hamam, J. Magistretti, 2001, Neuroscience.

The intracellular segment of the sodium channel beta 1 subunit is required for its efficient association with the channel alpha subunit.

J. Malhotra, D. Ragsdale, L. Isom, 2001, Journal of neurochemistry.

Kinetic diversity of single-channel burst openings underlying persistent Na(+) current in entorhinal cortex neurons.

A. Alonso, J. Magistretti, D. Ragsdale, 2003, Biophysical journal.

High Conductance Sustained Single-Channel Activity Responsible for the Low-Threshold Persistent Na+ Current in Entorhinal Cortex Neurons

A. Alonso, J. Magistretti, D. Ragsdale, 1999, The Journal of Neuroscience.

Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currents.

R. Rasmusson, D. Ragsdale, Xianming Wang, 2005, Biophysical journal.

Inhibition of rat brain glutamate receptors by philanthotoxin.

R. Miledi, N. Anis, A. Eldefrawi, 1989, The Journal of pharmacology and experimental therapeutics.

Activity-dependent changes in excitability of perirhinal cortex networks in vitro

M. Avoli, M. D'antuono, G. Biagini, 2014, Pflügers Archiv - European Journal of Physiology.