N. Shankaraiah

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Iodine‐Mediated Oxidative Annulation by C–C Cleavage: A Domino Synthetic Approach to Quinazolinones and Benzo[4,5]imidazo[1,2‐ c ]quinazolines

Kavitha Donthiboina, Geeta Sai Mani, N. Shankaraiah, 2020 .

An efficient solid-phase synthesis of biologically important DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine dimers (DSB-120) and their C2-fluorinated analogues

N. Shankaraiah, A. Kamal, K. Reddy, 2006 .

Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect.

Akash P Sakla, S. Bhargava, N. Shankaraiah, 2020, European journal of medicinal chemistry.

Molecular iodine-catalysed oxidative CO–C(alkyl) bond cleavage of aryl/heteroaryl alkyl ketones: an efficient strategy to access fused polyheterocycles

Geeta Sai Mani, N. Shankaraiah, A. Kamal, 2018 .

Cinnamide derived pyrimidine-benzimidazole hybrids as tubulin inhibitors: Synthesis, in silico and cell growth inhibition studies.

S. Bhargava, N. Shankaraiah, Sravani Sana, 2021, Bioorganic chemistry.

Water mediated Heck and Ullmann couplings by supported palladium nanoparticles: importance of surface polarity of the carbon spheres

N. Shankaraiah, A. Kamal, V. Srinivasulu, 2012 .

Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity

U. Lakshmi, N. Shankaraiah, Sravani Sana, 2020, Bioorganic Chemistry.

Design, synthesis of DNA-interactive 4-thiazolidinone-based indolo-/pyrroloazepinone conjugates as potential cytotoxic and topoisomerase I inhibitors.

N. Nagesh, C. Godugu, N. Shankaraiah, 2022, European journal of medicinal chemistry.

Expedition to Phenanthrene Nucleus: A Two‐decade Research on Bench

N. Shankaraiah, Venkata Rao Kaki, Ramya Tokala, 2021, Asian Journal of Organic Chemistry.

Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances.

N. Shankaraiah, Akash P. Sakla, Prajwal Dhokne, 2021, European journal of medicinal chemistry.

Synthesis of Combretastatin‐A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization

U. Lakshmi, C. Godugu, N. Shankaraiah, 2019, ChemMedChem.

Synthesis of indolo/pyrroloazepinone-oxindoles as potential cytotoxic, DNA-intercalating and Topo I inhibitors.

N. Nagesh, C. Godugu, N. Shankaraiah, 2022, Bioorganic chemistry.

β-Carboline tethered cinnamoyl 2-aminobenzamides as class I selective HDAC inhibitors: Design, synthesis, biological activities and modelling studies.

A. Kamal, J. Soni, C. Godugu, 2021, Bioorganic chemistry.

Design and Synthesis of DNA‐Interactive β‐Carboline–Oxindole Hybrids as Cytotoxic and Apoptosis‐Inducing Agents

C. Godugu, N. Shankaraiah, Sravani Sana, 2018, ChemMedChem.

Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.

N. Shankaraiah, N. P. Praveen Kumar, D. Prasanna, 2017, Bioorganic & medicinal chemistry.

Synthesis of DNA interactive C3-trans-cinnamide linked β-carboline conjugates as potential cytotoxic and DNA topoisomerase I inhibitors.

A. Kamal, N. Nagesh, N. Shankaraiah, 2018, Bioorganic & medicinal chemistry.

Iodine-mediated C–N and N–N bond formation: a facile one-pot synthetic approach to 1,2,3-triazoles under metal-free and azide-free conditions

Kavitha Donthiboina, Geeta Sai Mani, N. Shankaraiah, 2019, RSC advances.

Design and synthesis of 1,2,3-triazolo-phenanthrene hybrids as cytotoxic agents.

Pankaj Sharma, N. Shankaraiah, Shalini Nekkanti, 2017, Bioorganic & medicinal chemistry letters.

Design and synthesis of C3-tethered 1,2,3-triazolo-β-carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies.

A. Kamal, N. Nagesh, N. Shankaraiah, 2016, Bioorganic chemistry.

Recent advances in multi-component reactions and their mechanistic insights: a triennium review

N. Shankaraiah, S. Gulati, Stephy Elza John, 2021 .

Synthesis and biological evaluation of substituted N-(2-(1H-benzo[d]imidazol-2-yl)phenyl)cinnamides as tubulin polymerization inhibitors.

A. Kamal, C. Godugu, Kavitha Donthiboina, 2020, Bioorganic chemistry.

A one-pot azido reductive tandem mono-N-alkylation employing dialkylboron triflates: online ESI-MS mechanistic investigation.

N. Shankaraiah, A. Kamal, V. Srinivasulu, 2011, The Journal of organic chemistry.

Exploration of C‐H Activation Strategies in Construction of Functionalized 2‐Aryl Benzoazoles: A Decisive Review

N. Shankaraiah, Stephy Elza John, Steeva Sunny, 2021, Asian Journal of Organic Chemistry.

Design and synthesis of DNA-intercalative naphthalimide-benzothiazole/cinnamide derivatives: cytotoxicity evaluation and topoisomerase-IIα inhibition.

A. Kamal, N. Nagesh, N. Shankaraiah, 2019, MedChemComm.

Synthesis and potential cytotoxic activity of new phenanthrylphenol-pyrrolobenzodiazepines.

A. Kamal, M. J. Ramaiah, S. Pushpavalli, 2010, European journal of medicinal chemistry.

Syntheses and reactivity of spiro-epoxy/aziridine oxindole cores: developments in the past decade.

Akash P Sakla, N. Shankaraiah, Akash P. Sakla, 2020, Organic & biomolecular chemistry.

H2 O-Mediated Epoxide Ring-Opening with Concomitant C-S Bond Formation: A One-Pot Method to 3-Hydroxy-oxindolino-dithiocarbamates as Cytotoxic Agents

Pankaj Sharma, V. Talla, N. Shankaraiah, 2018, ChemistrySelect.

Enantioselective total syntheses of ropivacaine and its analogues

N. Shankaraiah, Leonardo S. Santos, R. Pilli, 2008 .

FeCl 3 ‐Catalyzed [3+2] Cycloaddition Reaction: A Mild Synthetic Approach to Spirooxindolo‐2‐iminothiazolidine Scaffolds

Akash P Sakla, N. Shankaraiah, Sonali Bhandari, 2020 .

Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding.

N. Nagesh, N. Shankaraiah, Sravani Sana, 2021, Bioorganic & medicinal chemistry.

TCCA-mediated oxidative rearrangement of tetrahydro-β-carbolines: facile access to spirooxindoles and the total synthesis of (±)-coerulescine and (±)-horsfiline

N. Shankaraiah, Leonardo S. Santos, Akash P. Sakla, 2021, RSC advances.

Enantioselective total synthesis of pyrroloquinolone as a potent PDE5 inhibitor

N. Shankaraiah, Leonardo S. Santos, 2009 .

A facile intramolecular azido/amido reductive cyclization approach: synthesis of pyrrolobenzodiazepines and their dimers

N. Shankaraiah, A. Kamal, K. Reddy, 2008 .

4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.

A. Kamal, M. J. Ramaiah, S. Pushpavalli, 2013, Bioorganic & medicinal chemistry.

Catalyst‐Free Site‐Selective Diverse Functionalization of Inherent C–H Bonds in 1‐Aryl‐β‐carbolines, Norharmane and Harmine

J. Soni, N. Shankaraiah, M. Sathish, 2022, ChemistrySelect.

Stereoselective Aldol and Conjugate Addition Reactions Mediated by Proline‐Based Catalysts and Its Analogues: A Concise Review

N. Shankaraiah, Manasa Kadagathur, Durgesh Gurukkala Valapil, 2021, European Journal of Organic Chemistry.

Enantioselective total synthesis of (s)-(+)-lennoxamine through asymmetric hydrogenation mediated by l-proline-tetrazole ruthenium catalyst

N. Shankaraiah, Leonardo S. Santos, Yaneris Mirabal-Gallardo, 2012 .

Asymmetric syntheses of piperidino-benzodiazepines through ‘cation-pool’ host/guest supramolecular approach and their DNA-binding studies

N. Shankaraiah, A. Kamal, Leonardo S. Santos, 2010 .

Short synthesis of noscapine, bicuculline, egenine, capnoidine, and corytensine alkaloids through the addition of 1-siloxy-isobenzofurans to imines

N. Shankaraiah, Leonardo S. Santos, M. C. Soriano, 2010 .

H2O-mediated isatin spiro-epoxide ring opening with NaCN: Synthesis of novel 3-tetrazolylmethyl-3-hydroxy-oxindole hybrids and their anticancer evaluation.

A. Kamal, N. Shankaraiah, Manish Kumar Jeengar, 2015, European journal of medicinal chemistry.

Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.

A. Kamal, V. L. Nayak, N. Nagesh, 2018, European journal of medicinal chemistry.

Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.

N. Jain, A. Kamal, Sowjanya Polepalli, 2014, Bioorganic & medicinal chemistry.

Synthesis of enamino-2-oxindoles via conjugate addition between α-azido ketones and 3-alkenyl oxindoles: Cytotoxicity evaluation and apoptosis inducing studies.

A. Kamal, B. Sridhar, C. Godugu, 2018, Bioorganic & medicinal chemistry letters.

Recent advances in the solid-phase combinatorial synthetic strategies for the quinoxaline, quinazoline and benzimidazole based privileged structures.

A. Kamal, N. Shankaraiah, K. Reddy, 2006, Mini reviews in medicinal chemistry.

A recyclable and water soluble copper(I)-catalyst: one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their biological evaluation

N. Shankaraiah, Ramya Tokala, Shalini Nekkanti, 2016 .

An efficient one-pot decarboxylative aromatization of tetrahydro-β-carbolines by using N-chlorosuccinimide: total synthesis of norharmane, harmane and eudistomins

N. Shankaraiah, A. Kamal, V. Srinivasulu, 2015 .

Novel supramolecular palladium catalyst for the asymmetric reduction of imines in aqueous media.

Manoel T. Rodrigues, C. K. Andrade, N. Shankaraiah, 2009, Organic letters.

Corrigendum to “Enantioselective total synthesis of pyrroloquinolone as a potent PDE5 inhibitor” [Tetrahedron Lett. 50 (2009) 520]

N. Shankaraiah, Leonardo S. Santos, 2009 .

Enantioselective total synthesis of (S)-()-quinolactacin B

C. K. Andrade, N. Shankaraiah, Leonardo S. Santos, 2008 .

Synthesis and cytotoxicity evaluation of DNA-interactive β-carboline indolyl-3-glyoxamide derivatives: Topo-II inhibition and in silico modelling studies.

N. Nagesh, J. Soni, N. Shankaraiah, 2022, Bioorganic chemistry.

Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction.

N. Nagesh, N. Shankaraiah, Sravani Sana, 2020, Bioorganic chemistry.

Synthesis and in vitro cytotoxicity evaluation of β-carboline-combretastatin carboxamides as apoptosis inducing agents: DNA intercalation and topoisomerase-II inhibition.

A. Kamal, S. Bhargava, N. Nagesh, 2019, Bioorganic & medicinal chemistry.

Chemoselective aromatic azido reduction with concomitant aliphatic azide employing Al/Gd triflates/NaI and ESI-MS mechanistic studies.

M. Eberlin, N. Shankaraiah, A. Kamal, 2009, Chemistry.

Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update

N. Shankaraiah, P. Kumari, Kritika Laxmikeshav, 2021, Medicinal research reviews.

Rh(III)-catalysed site-selective alkylation of β-carbolines/isoquinolines and tandem C H/C N functionalization to construct indolizine-indole frameworks

N. Shankaraiah, M. Sathish, Stephy Elza John, 2022, Molecular Catalysis.

The role of sulphonamides and N-sulphonyl ketimines/aldimines as directing groups in the field of C-H activation.

N. Shankaraiah, Darshana Bora, Mary Sravani Galla, 2021, Chemistry, an Asian journal.

Iron-Mediated One-Pot Synthesis of 3,5-Diarylpyridines from β-Nitrostyrenes.

N. Shankaraiah, A. Kamal, A. Alarifi, 2016, The Journal of organic chemistry.

TBAI/TBHP-catalyzed [3 + 2]cycloaddition/oxidation/aromatization cascade and online ESI-MS mechanistic studies: synthesis of pyrrolo[2,1-a]isoquinolines and indolizino[8,7-b]indoles

N. Shankaraiah, A. Kamal, Leonardo S. Santos, 2016 .

Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines by employing polymer-supported reagents: Preparation of DC-81

N. Shankaraiah, A. Kamal, K. Reddy, 2004 .

Copper Oxide Nanoparticles Supported on Graphene Oxide‐ Catalyzed S‐Arylation: An Efficient and Ligand‐Free Synthesis of Aryl Sulfides

N. Nagesh, N. Shankaraiah, A. Kamal, 2013 .

Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects

N. Shankaraiah, Stephy Elza John, Shivani Gulati, 2021, Beilstein journal of organic chemistry.

Synthesis of substituted phenanthrene-9-benzimidazole conjugates: Cytotoxicity evaluation and apoptosis inducing studies.

Pankaj Sharma, A. Kamal, N. Shankaraiah, 2017, European journal of medicinal chemistry.

An insight into medicinal attributes of dithiocarbamates: Bird's eye view.

Akash P Sakla, N. Shankaraiah, Akash P. Sakla, 2020, Bioorganic chemistry.

The microwave-assisted syntheses and applications of non-fused single-nitrogen-containing heterocycles.

J. Soni, N. Shankaraiah, Swanand Vinayak Joshi, 2020, Organic & biomolecular chemistry.

Reliability of Click Chemistry on Drug Discovery: A Personal Account.

Nagula Shankaraiah, Akash P Sakla, Kritika Laxmikeshav, 2020, Chemical record.

Selective reduction of aromatic azides in solution/solid-phase and resin cleavage by employing BF3·OEt2/EtSH. Preparation of DC-81

N. Shankaraiah, A. Kamal, K. Reddy, 2006 .

Microwave-assisted one-pot synthesis of new phenanthrene fused-tetrahydrodibenzo-acridinones as potential cytotoxic and apoptosis inducing agents.

Pankaj Sharma, A. Kamal, S. Bhargava, 2018, European journal of medicinal chemistry.

Microwave‐Assisted One‐Pot [3+2] Cycloaddition of Azomethine Ylides and 3‐Alkenyl Oxindoles: A Facile Approach to Pyrrolidine‐Fused Bis‐Spirooxindoles

N. Shankaraiah, Sravani Sana, Sonali Bhandari, 2019, ChemistrySelect.

Base-mediated 1,3-dipolar cycloaddition of pyridinium bromides with bromoallyl sulfones: a facile access to indolizine scaffolds.

N. Shankaraiah, A. Kamal, Chetna Jadala, 2020, Organic & biomolecular chemistry.

Synthesis of (Z)-3-(arylamino)-1-(3-phenylimidazo[1,5-a]pyridin-1-yl)prop-2-en-1-ones as potential cytotoxic agents.

A. Kamal, C. Godugu, Kavitha Donthiboina, 2020, Bioorganic & medicinal chemistry letters.

Microwave-assisted direct oxidative synthesis of α-ketoamides from aryl methyl ketones and amines by a water soluble Cu(I)-complex

N. Shankaraiah, Shalini Nekkanti, N. P. Kumar, 2016 .

Transition metal-free one-pot synthesis of substituted pyrroles by employing aza-Wittig reaction

N. Shankaraiah, A. Kamal, Chetna Jadala, 2019, RSC advances.

Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity.

A. Kamal, S. Prabhakar, N. Shankaraiah, 2008, Bioorganic & medicinal chemistry letters.

Conversion of Amines to Imines Employing Polymer‐Supported Sulfoxide (PSS) and Polymer‐Supported Perruthenate (PSP): Synthesis of Pyrrolo[2,1‐c][1,4]benzodiazepines

N. Shankaraiah, A. Kamal, K. Reddy, 2006 .

A new approach for the solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepines involving reductive cleavage

N. Shankaraiah, A. Kamal, K. Reddy, 2004 .

Syntheses and medicinal chemistry of azepinoindolones: a look back to leap forward.

N. Shankaraiah, D. K. Sigalapalli, S. Patra, 2021, Organic & biomolecular chemistry.

An update on the progress of cycloaddition reactions of 3-methyleneindolinones in the past decade: versatile approaches to spirooxindoles.

N. Shankaraiah, Akash P. Sakla, Ruqaiya Saeed, 2021, Organic & biomolecular chemistry.

Selective Reduction of Aromatic Azides in Solution/Solid-Phase and Resin Cleavage by Employing BF3×OEt2/EtSH. Preparation of DC-81.

N. Shankaraiah, A. Kamal, K. Reddy, 2006 .

Effect of Sulfamic Acid on 1,3-Dipolar Cycloaddition Reaction: Mechanistic Studies and Synthesis of 4-Aryl-NH-1,2,3-triazoles from Nitroolefins

N. Shankaraiah, Leonardo S. Santos, O. Forero-Doria, 2016 .

β-Carboline directed regioselective hydroxylation by employing Cu(OAc)2 and mechanistic investigation by ESI-MS.

N. Shankaraiah, Ramya Tokala, B. Prasanth, 2020, Organic & biomolecular chemistry.

Application of Transition Metal‐Catalyzed C−H Activation Strategies in the Synthesis and Functionalization of β‐Carbolines

N. Shankaraiah, K. Riyazahmed, Darshana Bora, 2021 .

Cyclodesulfurization: An Enabling Protocol for Synthesis of Various Heterocycles

N. Shankaraiah, D. K. Sigalapalli, Manasa Kadagathur, 2021 .

Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines

N. Shankaraiah, Sravani Sana, Sonali Bhandari, 2020, RSC advances.

Lewis-acid catalyzed dehydrative [3+2] cycloaddition reaction: A facile synthetic approach to spiro-benzoindoline oxindoles

N. Shankaraiah, Sonali Bhandari, Akash P. Sakla, 2020 .

Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.

Ahmed Kamal, N Shankaraiah, Subrata Sen, 2008, Bioorganic & medicinal chemistry letters.

Iodine-promoted one-pot synthesis of 1,3,4-oxadiazole scaffolds via sp3 C–H functionalization of azaarenes

Kavitha Donthiboina, Geeta Sai Mani, N. Shankaraiah, 2019, New Journal of Chemistry.

Iodine promoted dual oxidative C(sp3)-H amination of 2-methyl-3-arylquinazolin-4(3H)-ones: a facile route to 1,4-diarylimidazo[1,5-a]quinazolin-5(4H)-ones.

J. Nanubolu, Kavitha Donthiboina, N. Shankaraiah, 2018, Organic & biomolecular chemistry.

The Riveting Chemistry of Poly‐ aza ‐heterocycles Employing Microwave Technique: A Decade Review

J. Soni, N. Shankaraiah, Swanand Vinayak Joshi, 2021 .

Microwave‐Assisted Regioselective Friedel–Crafts Arylation by BF 3 ⋅ OEt 2 : A Facile Synthetic Access to 3‐Substituted‐3‐Propargyl Oxindole Scaffolds

Akash P Sakla, N. Shankaraiah, Akash P. Sakla, 2020 .

Ru(II)-Catalyzed Regioselective Hydroxymethylation of β-Carbolines and Isoquinolines via C-H Functionalization: Probing the Mechanism by Online ESI-MS/MS Screening.

N. Shankaraiah, Sravani Sana, Leonardo S. Santos, 2019, The Journal of organic chemistry.

Conventional and microwave-assisted synthesis of new 1H-benzimidazole-thiazolidinedione derivatives: A potential anticancer scaffold.

S. Bhargava, N. Shankaraiah, T. S. Reddy, 2017, European journal of medicinal chemistry.

Silver(I)-catalysed domino alkyne-annulation/Diels–Alder reaction: a mild synthetic approach to tetrahydrospiro[carbazole-4,3′-indoline] scaffolds

B. Sridhar, N. Shankaraiah, P. Sharma, 2016 .

Silver catalyzed domino aza-annulation/Diels-Alder cyclization of 2-ene-yne anilines: a facile one-pot access to carbazole, dihydrocarbazole and tetrahydrocarbazole frameworks.

A. Saraswati, N. Shankaraiah, A. Kamal, 2016, Chemical communications.

Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.

V. Talla, U. Lakshmi, N. Nagesh, 2019, Bioorganic chemistry.

Solid-phase synthesis of fused [2,1-b]quinazolinone alkaloids

N. Shankaraiah, A. Kamal, K. Reddy, 2006 .

Sulfamic acid promoted one-pot synthesis of phenanthrene fused-dihydrodibenzo-quinolinones: Anticancer activity, tubulin polymerization inhibition and apoptosis inducing studies.

A. Kamal, U. Lakshmi, C. Godugu, 2018, Bioorganic & medicinal chemistry.

One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.

A. Kamal, N. Shankaraiah, Manish Kumar Jeengar, 2015, Bioorganic & medicinal chemistry letters.

AlCl3-NaI assisted cleavage of polymer-bound esters with concomitant amine coupling and azido-reductive cyclization: synthesis of pyrrolobenzodiazepine derivatives

S. Prabhakar, N. Shankaraiah, A. Kamal, 2013 .

Synthesis of C8–C8/C2–C8-linked triazolo pyrrolobenzodiazepine dimers by employing ‘click’ chemistry and their DNA-binding affinity

S. Prabhakar, N. Shankaraiah, A. Kamal, 2008 .

Recent advances in the solid-phase combinatorial synthetic strategies for the benzodiazepine based privileged structures.

A. Kamal, N. Shankaraiah, K. Reddy, 2006, Mini reviews in medicinal chemistry.

Facile and Efficient Solid-Phase Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepines

N. Shankaraiah, A. Kamal, K. Reddy, 2004 .

Dithiocarbamate/piperazine bridged pyrrolobenzodiazepines as DNA-minor groove binders: synthesis, DNA-binding affinity and cytotoxic activity.

N. Shankaraiah, A. Kamal, V. Srinivasulu, 2015, Bioorganic chemistry.

Chemoselective aromatic azido reduction with concomitant aliphatic azide employing Al/Gd triflates/NaI and ESI-MS mechanistic studies.

M. Eberlin, N. Shankaraiah, A. Kamal, 2009, Chemistry.

A Polymer-Assisted Solution-Phase Strategy for the Synthesis of Fused [2,1-b]Quinazolinones and the Preparation of Optically Active Vasicinone

N. Shankaraiah, A. Kamal, K. Reddy, 2006 .

Microwave-assisted oxidation reactions

N. Shankaraiah, Ramya Tokala, 2021 .

Anticancer potential of spirocompounds in medicinal chemistry: A pentennial expedition.

N. Shankaraiah, A. Kaushal, Darshana Bora, 2021, European journal of medicinal chemistry.

An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.

A. Kamal, N. Shankaraiah, M. S. Kumar, 2011, Bioorganic & medicinal chemistry letters.

Asymmetric Michael addition of ketones to nitroolefins: pyrrolidinyl-oxazole-carboxamides as new efficient organocatalysts.

A. Kamal, N. Shankaraiah, V. Srinivasulu, 2014, Organic & biomolecular chemistry.

Studies towards the construction of quaternary indolizidines by [2,3]-sigmatropic rearrangement cocatalyzed by ionic liquid

N. Shankaraiah, Leonardo S. Santos, Daniela A. Geraldo, 2009 .

Synthesis of bis-1,2,3-triazolo-bridged unsymmetrical pyrrolobenzodiazepine trimers via ‘click’ chemistry and their DNA-binding studies

Ahmed Kamal, G. Narahari Sastry, Hemant Kumar Srivastava, 2010 .

Synthesis and biological evaluation of new benzimidazole-thiazolidinedione hybrids as potential cytotoxic and apoptosis inducing agents.

Pankaj Sharma, S. Bhargava, N. Shankaraiah, 2016, European journal of medicinal chemistry.

Design, synthesis and anticancer evaluation of tetrahydro-β-carboline-hydantoin hybrids.

Pankaj Sharma, N. Shankaraiah, A. Kamal, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of 1,2,3‐Triazolo‐fused‐tetrahydro‐β‐carboline Derivatives via 1,3‐Dipolar Cycloaddition Reaction: Cytotoxicity Evaluation and DNA‐Binding studies

C. Godugu, N. Shankaraiah, Venkatesh Pooladanda, 2017 .

Microwave-Assisted Direct Oxidative Synthesis of α-Ketoamides from Aryl Methyl Ketones and Amines by a Water Soluble Cu(I)-Complex.

N. Shankaraiah, Shalini Nekkanti, N. P. Kumar, 2016 .

Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability.

A. Kamal, N. Nagesh, N. Shankaraiah, 2015, Bioorganic & medicinal chemistry.

DNA-binding affinity and anticancer activity of β-carboline-chalcone conjugates as potential DNA intercalators: Molecular modelling and synthesis.

Pankaj Sharma, A. Kamal, N. Nagesh, 2015, Bioorganic chemistry.

Design and Synthesis of C3‐Pyrazole/Chalcone‐Linked Beta‐Carboline Hybrids: Antitopoisomerase I, DNA‐Interactive, and Apoptosis‐Inducing Anticancer Agents

A. Kamal, N. Rangaraj, N. Nagesh, 2014, ChemMedChem.

Total Synthesis of Rutaecarpine and Analogues by Tandem Azido Reductive Cyclization Assisted by Microwave Irradiation

N. Shankaraiah, A. Kamal, Leonardo S. Santos, 2011 .

Synthesis of 2-aryl-1,2,4-oxadiazolo-benzimidazoles: Tubulin polymerization inhibitors and apoptosis inducing agents.

A. Kamal, N. Shankaraiah, V. Srinivasulu, 2015, Bioorganic & medicinal chemistry.

Palladium‐Catalyzed Aryl CH Activation and Tandem ortho‐Hydroxylation/Alkoxylation of 2‐Aryl Benzimidazoles: Cytotoxicity and DNA‐Binding Studies

M. N. Rao, N. Nagesh, N. Shankaraiah, 2014 .

Solid-phase synthesis of a library of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones with potential antitubercular activity.

A. Kamal, N. Shankaraiah, K. Reddy, 2007, Journal of combinatorial chemistry.

Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents.

C. Godugu, N. Shankaraiah, Swarna Bale, 2018, Bioorganic & medicinal chemistry letters.

Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers.

A. Kamal, M. J. Ramaiah, S. Pushpavalli, 2011, European journal of medicinal chemistry.

A one-pot ‘click’ reaction from spiro-epoxides catalyzed by Cu(I)-pyrrolidinyl-oxazole-carboxamide

Pankaj Sharma, B. Sridhar, N. Shankaraiah, 2015 .

Spirooxindole-derived morpholine-fused-1,2,3-triazoles: Design, synthesis, cytotoxicity and apoptosis inducing studies.

A. Kamal, N. Shankaraiah, Manish Kumar Jeengar, 2015, European journal of medicinal chemistry.

Short total synthesis of (-)-lupinine and (-)-epiquinamide by double Mitsunobu reaction

N. Shankaraiah, Leonardo S. Santos, Yaneris Mirabal-Gallardo, 2011 .

Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors.

N. Jain, A. Kamal, Sowjanya Polepalli, 2014, Bioorganic & medicinal chemistry letters.

An Efficient Selective Reduction of Aromatic Azides to Amines Employing BF3·OEt2/NaI : Synthesis of Pyrrolobenzodiazepines

N. Shankaraiah, A. Kamal, C. S. Reddy, 2008 .

Design, Synthesis and Biological Activity of A-C8/C-C2-Linked 6-Chloropurine-Pyrrolobenzodiazepine Hybrids as Anticancer Agents

S. Sen, N. Shankaraiah, A. Kamal, 2007 .

Synthesis and Biological Activity of C-8 Fluoroaryl Substituted Pyrimidine Linked-Pyrrolobenzodiazepine Conjugates

N. Shankaraiah, A. Kamal, K. Reddy, 2005 .

Ru(II)-Catalyzed Regioselective C–N Bond Formation on Benzothiazoles Employing Acyl Azide as an Amidating Agent

N. Shankaraiah, Vivek Dhiman, G. Samanthula, 2021, ACS omega.

New (E)-1-alkyl-1H-benzo[d]imidazol-2-yl)methylene)indolin-2-ones: Synthesis, in vitro cytotoxicity evaluation and apoptosis inducing studies.

N. Shankaraiah, Dinesh Thummuri, V. Naidu, 2016, European journal of medicinal chemistry.

Benzimidazole based bis-carboxamide derivatives as promising cytotoxic agents: Design, synthesis, in silico and tubulin polymerization inhibition

Pooja Sharma, O. Kulkarni, N. Nagesh, 2022, Journal of Molecular Structure.

Targeting tubulin polymerization and DNA binding of 4-thiazolidinone–umbelliferone hybrids: synthesis and cytotoxicity evaluation

N. Nagesh, N. Shankaraiah, Ramya Tokala, 2021, New Journal of Chemistry.

Future of Drug Discovery

N. Shankaraiah, A. Kamal, M. Sathish, 2017 .

β-Carboline-based molecular hybrids as anticancer agents: a brief sketch.

J. Soni, N. Shankaraiah, Y. Yeole, 2021, RSC medicinal chemistry.

Unravelling KDM4 histone demethylase inhibitors for cancer therapy.

N. Shankaraiah, Stephin Baby, G. V. Durgesh, 2021, Drug discovery today.

Exploration of Benzimidazoles as Potential Microtubule Modulators: An Insight in the Synthetic and Therapeutic Evolution

N. Shankaraiah, Kritika Laxmikeshav, Ambati Himaja, 2021, Journal of Molecular Structure.

Syntheses and Applications of Spirocyclopropyl Oxindoles: A Decade Review

Akash P Sakla, N. Shankaraiah, Akash P. Sakla, 2020 .

Diverse targeted approaches to battle multidrug resistance in cancer.

N. Shankaraiah, Shalini Nekkanti, Ojaswitha Ommi, 2019, Current medicinal chemistry.

Design and Synthesis of 5‐Morpholino‐Thiophene‐Indole/ Oxindole Hybrids as Cytotoxic Agents

Akash P Sakla, V. Talla, C. Godugu, 2020 .

Synthesis of substituted biphenyl methylene indolinones as apoptosis inducers and tubulin polymerization inhibitors.

A. Kamal, C. Godugu, Kavitha Donthiboina, 2019, Bioorganic chemistry.

Design and synthesis of 4'-O-alkylamino-tethered-benzylideneindolin-2-ones as potent cytotoxic and apoptosis inducing agents.

Pankaj Sharma, N. Shankaraiah, Dinesh Thummuri, 2016, Bioorganic & medicinal chemistry letters.

Triazolo‐linked benzimidazoles as tubulin polymerization inhibitors and DNA intercalators: Design, synthesis, cytotoxicity, and docking studies

N. Nagesh, C. Godugu, N. Shankaraiah, 2023, Archiv der Pharmazie.

Design, synthesis and apoptosis inducing effect of novel (Z)-3-(3'-methoxy-4'-(2-amino-2-oxoethoxy)-benzylidene)indolin-2-ones as potential antitumour agents.

Pankaj Sharma, N. Shankaraiah, Dinesh Thummuri, 2016, European journal of medicinal chemistry.

Development of hydrazide hydrazone-tethered combretastatin-oxindole derivatives as antimitotic agents

N. Shankaraiah, Anamika Sharma, Stephy Elza John, 2023, Journal of Molecular Structure.

Synthesis and Anticancer Activity of Chalcone‐Pyrrolobenzodiazepine Conjugates Linked via 1,2,3‐Triazole Ring Side‐Armed with Alkane Spacers.

M. J. Ramaiah, S. Pushpavalli, N. Shankaraiah, 2012 .

Niclosamide inhibits epithelial-mesenchymal transition with apoptosis induction in BRAF/ NRAS mutated metastatic melanoma cells.

C. Godugu, N. Shankaraiah, Venkatesh Pooladanda, 2023, Toxicology in vitro : an international journal published in association with BIBRA.

Contribution of Knoevenagel Condensation Products toward the Development of Anticancer Agents: An Updated Review

N. Shankaraiah, Ramya Tokala, Darshana Bora, 2022, ChemMedChem.

Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2,4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies

C. Godugu, N. Shankaraiah, Sravani Sana, 2018 .

Synthesis of Novel C3-Linked β-Carboline-Pyridine Derivatives Employing Khronke Reaction: DNA-binding Ability and Molecular Modeling Studies

Pankaj Sharma, N. Shankaraiah, A. Kamal, 2016 .

Synthesis of 2,3,6,7-tetramethoxyphenanthren-9-amine: An efficient precursor to access new 4-aza-2,3-dihydropyridophenanthrenes as apoptosis inducing agents.

Pankaj Sharma, A. Kamal, S. Bhargava, 2017, European journal of medicinal chemistry.

Exploration of cytotoxic potential and tubulin polymerization inhibition activity of cis-stilbene-1,2,3-triazole congeners.

C. Godugu, N. Shankaraiah, Anamika Sharma, 2023, RSC medicinal chemistry.

Exploration of Mercaptoacetamide-linked Pyrimidine-1,3,4-Oxadiazole Derivatives as DNA Intercalative Topo II inhibitors: Cytotoxicity and Apoptosis Induction.

N. Nagesh, N. Shankaraiah, Ramya Tokala, 2022, Bioorganic & medicinal chemistry letters.

Regioselective ortho‐sulfonamidation: Exploration of intrinsic directing property of β‐carbolines and their photophysical studies

N. Shankaraiah, Sravani Sana, R. Sonti, 2021, Asian Journal of Organic Chemistry.

A validated high‐performance liquid chromatography method for the determination of brassinin, an indoleamine 2,3‐dioxygenase inhibitor in rat plasma

Akash P Sakla, N. Shankaraiah, R. Sonti, 2023, SEPARATION SCIENCE PLUS.

Design, synthesis and in vitro cytotoxic evaluation of β-carboline tethered quinoline-4-carboxamide conjugates as DNA-interactive Topo II inhibitors

N. Nagesh, J. Soni, C. Godugu, 2023, Journal of Molecular Structure.

Efficient solid-phase synthesis of a library of imidazo[1,2-a]pyridine-8-carboxamides.

A. Kamal, N. Shankaraiah, K. Reddy, 2007, Journal of combinatorial chemistry.

Role of histone demethylases and histone methyltransferases in triple-negative breast cancer: Epigenetic mnemonics.

C. Godugu, N. Shankaraiah, Stephin Baby, 2022, Life sciences.

Asymmetric Michael addition of ketones to nitroolefins: pyrrolidinyl-oxazole-carboxamides as new efficient organocatalysts.

A. Kamal, N. Shankaraiah, V. Srinivasulu, 2014, Organic & biomolecular chemistry.

Regioselective synthesis and in vitro cytotoxicity evaluation of 3-thiooxindole derivatives: Tubulin polymerization inhibition and apoptosis inducing studies.

Akash P Sakla, C. Godugu, N. Shankaraiah, 2023, Bioorganic & medicinal chemistry.

Recent Horizons in Drug Discovery and Development

N. Shankaraiah, A. Kamal, Shalini Nekkanti, 2014 .

Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and in vitro cytotoxicity studies.

N. Nagesh, N. Shankaraiah, R. Phanindranath, 2023, Bioorganic & medicinal chemistry letters.

Development of Benzimidazole‐Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies

Akash P Sakla, N. Shankaraiah, Mohd Rabi Bazaz, 2024, ChemMedChem.

Microwave-Assisted Ru(II)-Catalyzed Regioselective Methyl Acylation of 2-Arylbenzoazoles: Synthesis of Benzofuran Conjugates via C-H Activation/Annulation.

N. Shankaraiah, Stephy Elza John, Sowmya Dastari, 2024, The Journal of organic chemistry.