J. Bégué

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Trifluoromethylcyclohexane as a new solvent? Limits of use

J. Legros, B. Crousse, D. Bonnet-Delpon, 2002 .

D. Bonnet-Delpon, J. Bégué, D. Bonnet‐Delpon, 2008 .

Stereoselective Synthesis of Peptidyl Trifluoromethyl Alcohols and Ketones: Inhibitory Potency Against Human Leucocyte Elastase, Cathepsin G, Porcine Pancreatic Elastase and HIV‐1 Protease

D. Bonnet-Delpon, J. Bégué, A. Amour, 1998, The Journal of pharmacy and pharmacology.

Recent Advances (1995‐2005) in Fluorinated Pharmaceuticals Based on Natural Products

D. Bonnet-Delpon, J. Bégué, D. Bonnet‐Delpon, 2006 .

Recent advances (1995–2005) in fluorinated pharmaceuticals based on natural products ☆

D. Bonnet-Delpon, J. Bégué, D. Bonnet‐Delpon, 2006 .

An efficient and robust fluoroketone catalyst epoxidation

J. Legros, B. Crousse, D. Bonnet-Delpon, 2001 .

One-pot synthesis of non-symmetric tetraoxanes with the H2O2/MTO/fluorous alcohol system

D. Bonnet-Delpon, J. Bégué, J. Iskra, 2003 .

Comparative study of the ring opening of 1-CF3-epoxy ethers mediated by Brönsted acids and hexafluoro-2-propanol

D. Bonnet-Delpon, J. Bégué, J. Iskra, 2005 .

Design of fluoroketones as efficient reagents for epoxidation reactions in hexafluoropropan-2-ol

J. Legros, B. Crousse, D. Bonnet-Delpon, 2002 .

Alkylation of manganese(II) tetraphenylporphyrin by antimalarial fluorinated artemisinin derivatives.

B. Meunier, D. Bonnet-Delpon, J. Bégué, 2003, Bioorganic & medicinal chemistry letters.

Fluoroartemisinins: Metabolically More Stable Antimalarial Artemisinin Derivatives

D. Bonnet-Delpon, J. Bégué, D. Bonnet‐Delpon, 2007, ChemMedChem.

Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.

Sébastien Charneau, P. Grellier, B. Crousse, 2004, Journal of medicinal chemistry.

First synthesis of 10 alpha-(trifluoromethyl)deoxoartemisinin.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002, Organic letters.

Anhydrodihydroartemisinin and its 10-trifluoromethyl analogue: access to novel d-ring-contracted artemisinin trifluoromethyl ketones.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002, The Journal of organic chemistry.

Synthesis and antimalarial activities of fluoroalkyl derivatives of dihydroartemisinin.

B. Pradines, D. Bonnet-Delpon, J. Bégué, 1998, Journal of medicinal chemistry.

Synthesis and in vivo antimatarial activity of 12α-trifluoromethyl-hydroartemisinin

D. Bonnet-Delpon, J. Bégué, J. Gantier, 1996 .

Preparation of 10-trifluoromethyl artemether and artesunate. Influence of hexafluoropropan-2-ol on substitution reaction.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2003, The Journal of organic chemistry.

Synthesis in fluorous phase: a convenient synthesis of isolongifolene epoxide and its rearrangement to ketone

D. Bonnet-Delpon, J. Bégué, M. Ourévitch, 2000 .

Selective oxidation of sulfides: selective preparation of 1-trifluoromethyl vinyl sulfoxides

D. Bonnet-Delpon, J. Bégué, K. S. Ravikumar, 1999 .

Manganese (III) acetate dihydrate catalyzed aerobic epoxidation of unfunctionalized olefins in fluorous solvents

D. Bonnet-Delpon, J. Bégué, K. S. Ravikumar, 1998 .

Cyclic oxonium salts:13C magnetic resonance spectroscopy. The correlation of chemical shifts with the calculated charge density

D. Bonnet-Delpon, J. Bégué, D. Bonnet‐Delpon, 1980 .

The future of antimalarials : artemisinins and synthetic endoperoxides

D. Bonnet-Delpon, J. Bégué, 2005 .

Ions α-cétocarbenium

J. Bégué, J. Sansoulet, M. Charpentier-Morize, 1978 .

Bioorganic and Medicinal Chemistry of Fluorine

D. Bonnet-Delpon, J. Bégué, Jean-Pierre Bégué, 2008 .

Synthesis of 2-CF(3)-tetrahydroquinoline and quinoline derivatives from CF(3)-N-aryl-aldimine.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2000, The Journal of organic chemistry.

Synthesis of tetrahydroquinoline derivatives from α-CF3-N-arylaldimine and vinyl ethers

B. Crousse, D. Bonnet-Delpon, J. Bégué, 1998 .

Preparation of trifluoromethyl ketones and related fluorinated ketones

D. Bonnet-Delpon, J. Bégué, D. Bonnet‐Delpon, 1991 .

The chemistry of trifluoromethyl imines and related acetals derived from fluoral.

J. Legros, B. Crousse, D. Bonnet-Delpon, 2005, Chemical Society reviews.

TRIFLUOROMETHYLALKENES IN CYCLOADDITION REACTIONS

D. Bonnet-Delpon, J. Bégué, T. Lequeux, 1996 .

Aza-Diels–Alder reaction in fluorinated alcohols. A one-pot synthesis of tetrahydroquinolines

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2003 .

Fluoro artemisinins: difluoromethylene ketones.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2001, The Journal of organic chemistry.

Fluorinated Synthons: Reactivity of 1-RF-Epoxy Ethers with Lewis Acids

D. Bonnet-Delpon, J. Bégué, F. Benayoud, 1995 .

Lewis acid induced ene cyclization of ω-olefinic trifluoromethyl ketones : access to bicyclic compounds bearing a CF3 group

D. Bonnet-Delpon, J. Bégué, A. Abouabdellah, 1991 .

Intramolecular ω-olefinic-ketone ene-reaction for the construction of trifluoromethylated five-membered ring compounds

J. Bégué, C. Aubert, 1988 .

Urea‐Hydrogen Peroxide/Hexafluoro‐2‐propanol: An Efficient System for a Catalytic Epoxidation Reaction without a Metal

J. Legros, B. Crousse, D. Bonnet-Delpon, 2002 .

Fluorinated Alcohols: A New Medium for Selective and Clean Reaction

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2004 .

Methyltrioxorhenium-catalysed epoxidation of alkenes: enhancement of reactivity in hexafluoro-2-propanol

D. Bonnet-Delpon, J. Bégué, J. Iskra, 2002 .

Role of Hexafluoro‐2‐propanol in Selective Oxidation of Sulfide to Sulfoxide: Efficient Preparation of Glycosyl Sulfoxides

Yongming Zhang, D. Bonnet-Delpon, J. Bégué, 1998 .

A SELECTIVE CONVERSION OF SULFIDE TO SULFOXIDE IN HEXAFLUORO-2-PROPANOL

D. Bonnet-Delpon, J. Bégué, K. S. Ravikumar, 1998 .

A convenient synthesis of fluoroalkyl and fluoroaryl glycosides using Mitsunobu conditions

D. Bonnet-Delpon, J. Bégué, D. Gueyrard, 1999 .

Claisen rearrangement of α-(F-alkyl)enol ethers prepared via Wittig olefination of allyl perfluoroalkanoates

T. Nakai, D. Bonnet-Delpon, J. Bégué, 1994 .

Short and efficient preparation of trifluoromethyl vinyl sulphides

D. Bonnet-Delpon, J. Bégué, Abderrahim M'bida, 1993 .

The Wittig reaction of perfluoro acid derivatives: access to fluorinated enol ethers, enamines, and ketones

D. Bonnet-Delpon, J. Bégué, Sheng-Wen Wu, 1992 .

Nouvelle synthese de trifluoromethylcetones et d' /ga-bromo trifluoromethylcetones

J. Bégué, D. Mesureur, 1988 .

β'β anionic elimination of carboxylic esters

J. Biellmann, J. Bégué, C. Aubert, 1986 .

Methods generale d'acess aux trifluoromethylcetones. 1ère partie: Alkylation directe du trifluoroacetylacetate d'ethyle

B. Langlois, J. Bégué, C. Aubert, 1989 .

Trifluoromethylated furans via iodocyclisation of γ-unsaturated ethyl trifluoroacetoacetates

D. Bonnet-Delpon, J. Bégué, M. Ourévitch, 1993 .

Synthesis of (Trifluoromethyl)aziridines in 1,1,1,3,3,3-Hexafluoropropan-2-ol: First Example of Coupling Reactions of Fluoral, an Amine and a Diazo Compound

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002 .

A simple preparation of alkyl trifluoromethanesulfonates (triflates) from alkyl trimethylsilyl ethers

J. Bégué, C. Aubert, 1985 .

Vinylogous Mannich reactions. Additions of trimethylsilyloxyfuran to fluorinated aldimines

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2004 .

Highly selective 1,3-dipolar cycloaddition of a cyclic azomethine ylide to ethyltrifluorocrotonates

D. Bonnet-Delpon, J. Bégué, M. Ourévitch, 2001 .

Synthesis and biological activity of novel 3′-trifluoromethyl taxoids

J. Veith, I. Ojima, J. Bégué, 1997 .

Diastereoselective Synthesis of the Nonracemic Methyl syn-(3-Fluoroalkyl)isoserinates

D. Bonnet-Delpon, J. Bégué, A. Abouabdellah, 1997 .

Enhancement of alkene reactivity by a trifluoromethyl group: Synthesis of pyrrolidines via 1,3-dipolar cycloaddition

J. Bégué, Danièle Bonnet-Delpon aThierry Lequeux, 1993 .

A Novel Approach to the Study of Solution Structures and Dynamic Behavior of Paclitaxel and Docetaxel Using Fluorine-Containing Analogs as Probes

S. Kuduk, S. Chakravarty, I. Ojima, 1997 .

Lewis acid-induced ene-cyclization of ω-olefinic trifluoromethyl ketones: access to alicyclic compounds bearing a CF3 group

D. Bonnet-Delpon, J. Bégué, C. Aubert, 1991 .

Lewis Acid-Induced Stereoselective Ene-Cyclization of ω-Unsaturated Trifluoromethylketones

D. Bonnet-Delpon, J. Bégué, C. Aubert, 1989 .

Preparation of trifluoromethyl ketones and related fluorinated ketones

D. Bonnet-Delpon, J. Bégué, 1991 .

Fluoro alcohol as reaction medium: one-pot synthesis of β-hydroxy sulfoxides from epoxides

V. Kesavan, D. Bonnet-Delpon, J. Bégué, 2000 .

Asymmetric microbial reduction of tetralones

J. Bégué, S. Sicsic, C. Cerceau, 1992 .

Stereoselective synthesis and inhibitor properties towards human leucocyte elastase of chiral β-peptidyl trifluoromethyl alcohols.

D. Bonnet-Delpon, J. Bégué, A. Amour, 1994 .

Intramolecular ω-Olefinic Ketone Ene-Reaction for the Construction of Trifluoromethylated Five-Membered Ring Compounds.

J. Bégué, C. Aubert, 1988 .

Lewis Acid Induced Ene Cyclization of ω‐Olefinic Trifluoromethyl Ketones: Access to Bicyclic Compounds Bearing a CF3 Group.

D. Bonnet-Delpon, J. Bégué, A. Abouabdellah, 1992 .

Oxidation in Fluoro Alcohols: Mild and Efficient Preparation of Disulfides from Thiols

V. Kesavan, D. Bonnet-Delpon, J. Bégué, 2000 .

Novel [1,2]- and [2,3]-Wittig rearrangements of alpha-benzyloxy beta-CF(3)-beta-lactam enolates.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2001, Organic letters.

Stereoselective Barbier-type allylation reaction of trifluoromethyl aldimines.

J. Legros, B. Crousse, D. Bonnet-Delpon, 2003, The Journal of organic chemistry.

Synthesis of new artemisinin-derived dimers by self-cross-metathesis reaction.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2005, Organic letters.

.alpha.-Acylcarbenium ions

J. Bégué, M. Charpentier-Morize, 1980 .

Access to trifluoromethylindanes; cycloalkylation of β-phenyl trifluoromethyl ketones, β-keto esters, and alcohols

D. Bonnet-Delpon, J. Bégué, C. Aubert, 1989 .

A new synthesis of 1-(trifluoromethyl)enamines and 1-(trifluoromethyl)alkylamines

J. Bégué, D. Mesureur, 1989 .

Synthesis of 2-CF3-Tetrahydroquinoline and Quinoline Derivatives from CF3-N-Arylaldimine.

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2000 .

SYNTHESIS OF 3-(ALKYLTHIO AND PHENYLTHIO)-1,1,1-TRIFLUOROALKAN-2-ONES VIA RING OPENING OF EPOXY ETHERS

D. Bonnet-Delpon, J. Bégué, A. Kornilov, 1996 .

Trifluoromethyl ketones derived from squalene: inhibition of the cholesterol biosynthesis in HepG2 cells

O. Boutaud, C. Richard, F. Schuber, 2000 .

Alkylation du trifluoroacetylacetate d'ethyle methode generale d'acces aux trifluoromethylcetones. 2ème Partie: alkylations indirects du TFAAE

B. Langlois, J. Bégué, C. Aubert, 1989 .

1, 3-Dipolar cycloaddition between ethyl trifluoroacetoacetate and N-(benzylidene)methylamine N-oxide

D. Bonnet-Delpon, J. Bégué, T. Lequeux, 1991 .

First Stereoselective Synthesis of cis 3-CF3-Aziridine-2-carboxylates. A Route to New (Trifluoromethyl) α-Functionalised β-Amino Acids

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2001 .

Stereoselective Barbier-type allylation reaction of trifluoromethyl aldimines.

J. Legros, B. Crousse, D. Bonnet-Delpon, 2003, The Journal of organic chemistry.

Preparation, isolation and chemical reactivity of the α-CF3-propargylium ion stabilized by a heterobimetallic [CoMo] cluster

B. Malézieux, D. Bonnet-Delpon, J. Bégué, 1995 .

Mild and Selective Oxidation of Sulfur Compounds in Trifluoroethanol: Diphenyl Disulfide and Methyl Phenyl Sulfoxide

V. Kesavan, B. Crousse, D. Bonnet-Delpon, 2003 .

Comparison of the mass spectrometric behaviour of fluorinated ethers and sulphides

P. Traldi, D. Favretto, D. Bonnet-Delpon, 1995 .

Carbocationic cyclizations initiated by dehalogenation of unsaturated α-bromoimine

D. Bonnet-Delpon, J. Bégué, M. Charpentier-Morize, 1985 .

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin.

B. Pradines, Sébastien Charneau, W. Charman, 2004, Journal of medicinal chemistry.

C-10-Fluorinated derivatives of dihydroartemisinin: difluoromethylene ketones

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2001 .

A versatile synthesis of amino trifluoromethyl ketones and Alcohols

D. Bonnet-Delpon, J. Bégué, H. Sdassi, 1992 .

Concise stereoselective synthesis of 1-perfluoroalkyl enamines via the addition of N-lithiated amines to enol ethers and their subsequent metalation to form new functionalized enamines

D. Bonnet-Delpon, J. Bégué, D. Bouvet, 1998 .

Fluoro-artemisinins: When a gem-difluoroethylene replaces a carbonyl group

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2006 .

Preparation of α,α-Disubstituted Trifluoromethyl Ketones via Suzuki Reaction of Bromoenamines

J. Legros, B. Crousse, D. Bonnet-Delpon, 2000 .

1-Trifluoromethyl epoxy ethers. Effect of hexafluoro-2-propanol on reactions with secondary aromatic amines: synthesis of 3-trifluoromethyl indole derivatives.

D. Bonnet-Delpon, J. Bégué, I. Rodrigues, 2001, The Journal of organic chemistry.

Addition of organolithium reagents to α-(trifluoromethyl)styrene: concise synthesis of functionalised gem-difluoroalkenes

D. Bonnet-Delpon, J. Bégué, M. Rock, 1996 .

Synthesis of Hindered and Functionalized 1-CF3 Substituted Olefins via a Carbolithiation−Elimination−Metalation Cascade

D. Bonnet-Delpon, J. Bégué, M. Rock, 1996 .

A concise synthesis of functionalised gem-difluoroalkenes, via the addition of organolithium reagents to α-trifluoromethylstyrene

D. Bonnet-Delpon, J. Bégué, M. Rock, 1995 .

Facile syntheses of gem-difluoroalkenes from chlorodifluoromethylketones

R. Wilkes, J. Percy, D. Bonnet-Delpon, 1995 .

Configurational assignment by 13C NMR of stereoisomeric 3‐bromo‐3‐acyl derivatives of 5α‐ and 5β‐ androstane

D. Bonnet-Delpon, J. Bégué, 1982 .

Palladium-catalyzed reaction of functionalized β-trifluoromethyl vinyl bromides with terminal alkynes and alkenes

J. Legros, B. Crousse, D. Bonnet-Delpon, 2001 .

First Synthesis of Methyl syn 3-CF3-Isoserinate

D. Bonnet-Delpon, J. Bégué, A. Abouabdellah, 1996 .

Regio- and stereoselective remote hydroxylations of the A ring of steroids. A novel route to 5-.alpha. steroids with cis-coupled A and B rings

J. Bégué, 1982 .

The Mass Spectrometric Behaviour of Some Halogen-Containing Epoxyethers

P. Traldi, D. Favretto, D. Bonnet-Delpon, 1997 .

Design, Synthesis and Antimalarial Activity of Trifluoromethylartemisinin–Mefloquine Dual Molecules

P. Grellier, D. Bonnet-Delpon, J. Bégué, 2005, Chembiochem : a European journal of chemical biology.

The addition of N-lithiated amines to 1,1,1-trifluoromethylstyrene, a concise synthesis of 3-gem-difluoro-2-phenyl allylic amines

D. Bonnet-Delpon, J. Bégué, M. Rock, 1995 .

The Addition of N-Lithiated Amines to 1,1,1,-Trifluoromethylstyrene, a Concise Synthesis of 3-gem-Difluoro-2-phenyl Allylic Amines.

D. Bonnet-Delpon, J. Bégué, M. Rock, 1995 .

The effect of 10 alpha-trifluoromethylhydroartemisinin on Plasmodium berghei infection and its toxicity in experimental animals.

L. Cong, D. Bonnet-Delpon, J. Bégué, 2002, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Allylic bromination of anhydrodihydroartemisinin and of its 10-trifluoromethyl analogue: a new access to 16-substituted artemisinin derivatives

B. Crousse, D. Bonnet-Delpon, J. Bégué, 2002 .

Determination of Z and E configurations in trifluoromethylated vinyl compounds: 3J(CF) coupling constants as a criterion for configurational assignments

D. Bonnet-Delpon, J. Bégué, M. Ourévitch, 1991 .

Palladium-Catalyzed Boronic Acid Cross-Coupling Reactions of β-Ethoxy β-Trifluoromethyl Vinyl Bromides

D. Bonnet-Delpon, J. Bégué, D. Bouvet, 1998 .

Cyclization of α‐substituted α,ω‐diphenylalkyl carbenium ions: Reactivity of α‐trifluoromethylbenzyl cations vs. α‐methylbenzyl cations

D. Bonnet-Delpon, J. Bégué, H. Grützmacher, 1993 .

A Novel Approach to the Study of Solution Structures and Dynamic Behavior of Paclitaxel and Docetaxel Using Fluorine‐Containing Analogues as Probes.

S. Kuduk, S. Chakravarty, I. Ojima, 1997 .

Electrosynthesis of new functionalized difluoro allylsilanes

D. Bonnet-Delpon, J. Bégué, S. Condon, 1998 .

New catalytic oxidation of trifluoromethyl carbinols by a ruthenium(II) complex

V. Kesavan, S. Chandrasekaran, D. Bonnet-Delpon, 2000 .

Analogues of key precursors of aspartyl protease inhibitors: synthesis of trifluoromethyl amino epoxides.

N. T. Tam, B. Crousse, D. Bonnet-Delpon, 2005, The Journal of organic chemistry.

Syntheses, Biological Activity, and Conformational Analysis of Fluorine-Containing Taxoids

S. Kuduk, S. Chakravarty, J. Veith, 1996 .

Conversion of trifluoromethyl carbonyl compounds to the corresponding vinylsilanes with cyclopentadienyltris(trimethylsilylmethyl) titanium(IV)

J. Bégué, M. Rock, 1995 .

Synthesis of allylic trifluoromethyl alcohols from 1-trifluoromethyl-epoxy ethers

J. Bégué, N. Fischer‐Durand, A. Kornilov, 1996 .

Cobalt-Induced C-N and C-C Bond Formation via Metal-Stabilized alpha-CF(3) Carbenium Ion.

B. Malézieux, J. Bégué, H. Amouri, 2000, Organic letters.

Effects of Fluorine Substitution on Biological Properties

J. Bégué, D. Bonnet‐Delpon, 2007 .

Facile ring opening of oxiranes with aromatic amines in fluoro alcohols

V. Kesavan, Kesavan, B. Crousse, 2000, The Journal of organic chemistry.