Beth C. Holbrook

发表

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction.

M. Willingham, R. Michalek, J. Grayson, 2008, Immunity.

Regulatory T Cell Expansion Postinfection through Increased Natural Effector Cell Number at Late Times High Viral Burden Restricts Short-Lived

Beth C. Holbrook, M. Alexander-Miller, Samuel Amoah, 2013 .

High Viral Burden Restricts Short-Lived Effector Cell Number at Late Times Postinfection through Increased Natural Regulatory T Cell Expansion

Beth C. Holbrook, M. Alexander-Miller, Samuel Amoah, 2013, The Journal of Immunology.

Adjuvanting an inactivated influenza vaccine with conjugated R848 improves the level of antibody present at 6months in a nonhuman primate neonate model.

R. D'Agostino, M. Jorgensen, Beth C. Holbrook, 2017, Vaccine.

Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model.

G. Parks, R. D'Agostino, Beth C. Holbrook, 2016, Vaccine.

A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model

G. Parks, R. D'Agostino, N. Kock, 2016, The Journal of Immunology.

Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection.

G. Parks, N. Kock, Beth C. Holbrook, 2015, Virology.

Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates

G. Parks, S. Mizel, N. Kock, 2015, Journal of Virology.

Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults

Michael E. DeWitt, Beth C. Holbrook, M. Alexander-Miller, 2023, Immunity & Ageing.

Frailty and Age Impact Immune Responses to Moderna COVID-19 mRNA Vaccine

Michael E. DeWitt, Beth C. Holbrook, M. Alexander-Miller, 2022, Research square.

Influenza infected newborn and adult monkeys exhibit a strong primary antibody response to hemagglutinin stem.

J. Yewdell, M. Kanekiyo, B. Graham, 2020, JCI insight.

The Requirement of Reversible Cysteine Sulfenic Acid Formation for T Cell Activation and Function1

J. Fetrow, R. Michalek, L. Daniel, 2007, The Journal of Immunology.

Analysis of R848 as an Adjuvant to Improve Inactivated Influenza Vaccine Immunogenicity in Elderly Nonhuman Primates

Beth C. Holbrook, M. Alexander-Miller, Kali F. Crofts, 2022, Vaccines.

IFNgamma-producing, virus-specific CD8+ effector cells acquire the ability to produce IL-10 as a result of entry into the infected lung environment.

G. Parks, Beth C. Holbrook, M. Alexander-Miller, 2010, Virology.

Coinfection with Streptococcus pneumoniae Negatively Modulates the Size and Composition of the Ongoing Influenza-Specific CD8+ T Cell Response

G. Parks, Beth C. Holbrook, M. Alexander-Miller, 2014, The Journal of Immunology.

Influenza-Specific CD 8 Composition of the Ongoing Negatively Modulates the Size and Streptococcus pneumoniae Coinfection with

Martha, G. Parks, Beth C. Holbrook, 2014 .

Electron Transport Complex I Is Required for CD8+ T Cell Function1

R. Michalek, Nathan Laniewski, J. Grayson, 2006, The Journal of Immunology.

TCR Dependent Metabolic Programming Regulates Autocrine IL-4 Production Resulting in Self-Tuning of the CD8+ T Cell Activation Setpoint

D. Soto-Pantoja, Beth C. Holbrook, M. Alexander-Miller, 2020, Frontiers in Immunology.

In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection.

Beth C. Holbrook, M. Alexander-Miller, Lance K. Blevins, 2013, Viral immunology.

CD4+ T Cell Subset Differentiation and Avidity Setpoint Are Dictated by the Interplay of Cytokine and Antigen Mediated Signals

E. Shiner, Beth C. Holbrook, M. Alexander-Miller, 2014, PloS one.

TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination

M. Kanekiyo, B. Graham, Beth C. Holbrook, 2022, npj Vaccines.

An R848 adjuvanted influenza vaccine promotes early activation of B cells in the draining lymph nodes of non‐human primate neonates

M. Jorgensen, Beth C. Holbrook, M. Alexander-Miller, 2018, Immunology.

The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells.

Beth C. Holbrook, M. Alexander-Miller, S. King, 2018, Vaccine.

Higher Frequency and Increased Expression of Molecules Associated with Suppression on T Regulatory Cells from Newborn Compared with Adult Nonhuman Primates

Beth C. Holbrook, M. Alexander-Miller, Beth C Holbrook, 2020, The Journal of Immunology.

Higher frequency and increased expression of molecules associated with suppression on Tregs from newborn compared to adult nonhuman primates

Beth C. Holbrook, M. Alexander-Miller, Beth C Holbrook, 2020 .

An R848 conjugated influenza virus vaccine elicits robust IgG to hemagglutinin stem in a newborn nonhuman primate model.

J. Yewdell, M. Kanekiyo, B. Graham, 2020, The Journal of infectious diseases.

The requirement of reactive oxygen intermediates for lymphocytic choriomeningitis virus binding and growth.

R. Michalek, J. Grayson, Beth C. Holbrook, 2008, Virology.

Role of Bim in Regulating CD8+ T-Cell Responses during Chronic Viral Infection

David A Hildeman, J. Grayson, Beth C. Holbrook, 2006, Journal of Virology.

Neuraminidase-specific antibody responses are generated in naive and vaccinated newborn nonhuman primates following virus infection.

Beth C. Holbrook, M. Alexander-Miller, Kali F. Crofts, 2020, JCI insight.

Maternal influenza vaccination preferentially boosts hemagglutinin stem‐specific antibody resulting in efficient transplacental transfer of stem‐specific IgG

B. Snively, Beth C. Holbrook, M. Alexander-Miller, 2023, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

An Analysis of Linker-Dependent Effects on the APC Activation and In Vivo Immunogenicity of an R848-Conjugated Influenza Vaccine

D. Parsonage, Xuewei Zhu, Beth C. Holbrook, 2023, Vaccines.

Partial reconstitution of virus-specific memory CD8+ T cells following whole body γ-irradiation

Nathan Laniewski, J. Grayson, Beth C. Holbrook, 2006 .