C. Soroka

发表

A C‐terminal tyrosine‐based motif in the bile salt export pump directs clathrin‐dependent endocytosis

J. Boyer, P. Lam, Shuhua Xu, 2012, Hepatology.

Adult sea lamprey tolerates biliary atresia by altering bile salt composition and renal excretion

J. Boyer, L. Hagey, C. Soroka, 2013, Hepatology.

Organic Solute Transporter Alpha Deficiency: A Disorder With Cholestasis, Liver Fibrosis, and Congenital Diarrhea

D. Jain, J. Boyer, R. Lifton, 2019, Hepatology.

OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.

P. Dawson, J. Boyer, Michael S Madejczyk, 2005, Hepatology.

Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat.

J. Boyer, J. Schuetz, C. Soroka, 2004, Journal of hepatology.

Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression.

J. Boyer, Shuhua Xu, C. Soroka, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Phloracetophenone-induced choleresis in rats is mediated through Mrp2.

J. Boyer, N. Ballatori, C. Soroka, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Cellular localization and up‐regulation of multidrug resistance–associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

J. Boyer, F. Azzaroli, John M. Lee, 2001, Hepatology.

Down‐regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis

J. Boyer, H. Koepsell, U. Beuers, 2004, Hepatology.

Nuclear factor erythroid 2–related factor 2 is a positive regulator of human bile salt export pump expression

J. Boyer, C. Soroka, S. Cai, 2009, Hepatology.

The Role of Bcrp in the Adaptive Response to Cholestasis

J. Boyer, C. Soroka, A. Mennone, 2010 .

Cyclic AMP stimulates sorting of the canalicular organic anion transporter (Mrp2/cMoat) to the apical domain in hepatocyte couplets.

D. Keppler, J. Boyer, H. Roelofsen, 1998, Journal of cell science.

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTα-OSTβ in cholestasis in humans and rodents

J. Boyer, N. Ballatori, M. Trauner, 2006 .

Peroxisome proliferator‐activated receptor α activates human multidrug resistance transporter 3/ATP‐binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion

J. Boyer, M. Ananthanarayanan, C. Soroka, 2014, Hepatology.

An evolutionarily ancient Oatp: insights into conserved functional domains of these proteins.

W. Wang, J. Boyer, N. Ballatori, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.

J. Boyer, C. Soroka, 2014, Molecular aspects of medicine.

Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis.

J. Boyer, S. Nundy, F. Suchy, 1996, Gastroenterology.

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

J. Boyer, M. Trauner, P. Meier, 2000, Gastroenterology.

Sorting of rat liver and ileal sodium-dependent bile acid transporters in polarized epithelial cells.

F. Suchy, A. Sun, M. Ananthanarayanan, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.

J. Boyer, N. Ballatori, M. Trauner, 2006, American journal of physiology. Gastrointestinal and liver physiology.

The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II.

J. Boyer, C. Soroka, Lin Wang, 2002, The Journal of clinical investigation.

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis.

D. Keppler, J. Boyer, F. Suchy, 1997, Gastroenterology.

Ursodeoxycholic acid diminishes Fas‐ligand–induced apoptosis in mouse hepatocytes

J. Boyer, F. Azzaroli, W. Mehal, 2002, Hepatology.

The Bile Salt Export Pump: Clinical and Experimental Aspects of Genetic and Acquired Cholestatic Liver Disease

J. Boyer, P. Lam, C. Soroka, 2010, Seminars in liver disease.

Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases.

J. Boyer, P. Lam, Shuhua Xu, 2007, American journal of physiology. Cell physiology.

Synthesis of intestinal basement membrane.

M. Weiser, B. Albini, C. Soroka, 1989, Immunological investigations.

Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.

J. Boyer, T. Kensler, L. Hagey, 2012, American journal of physiology. Gastrointestinal and liver physiology.

All-Trans-Retinoic Acid Improves Cholestasis in α-Naphthylisothiocyanate–Treated Rats and Mdr2−/− Mice

J. Boyer, C. Soroka, S. Cai, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis.

J. Boyer, N. Ballatori, C. Soroka, 2010, Seminars in liver disease.

Canalicular Export Pumps Traffic with Polymeric Immunoglobulin A Receptor on the Same Microtubule-associated Vesicle in Rat Liver*

J. Boyer, C. Soroka, M. Pate, 1999, The Journal of Biological Chemistry.

Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes.

J. Boyer, M. Pypaert, C. Rahner, 2006, Gastroenterology.

Mouse organic solute transporter α deficiency enhances renal excretion of bile acids and attenuates cholestasis

J. Boyer, N. Ballatori, L. Hagey, 2010, Hepatology.

Gastrin-dependent inhibitory effects of octreotide on the genesis of gastric ECLomas.

I. Modlin, J. Goldenring, C. Soroka, 1992, Surgery.

Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets.

J. Boyer, C. Soroka, 1995, Gastroenterology.

Ostα-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity.

G. Shulman, J. Boyer, N. Ballatori, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.

D. Jain, J. Boyer, X. Ouyang, 2017, JCI insight.

ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.

J. Boyer, C. Rahner, S. Gautam, 2009, Gastroenterology.

Possible role of transforming growth factor alpha in the pathogenesis of Ménétrier's disease: supportive evidence form humans and transgenic mice.

R. Coffey, D. Ahlquist, David C. Lee, 1992, Gastroenterology.

CFTR-associated ligand is a negative regulator of Mrp2 expression.

J. Boyer, C. Soroka, Kathy M. Harry, 2017, American journal of physiology. Cell physiology.

NHERF-1 Binds to Mrp2 and Regulates Hepatic Mrp2 Expression and Function*

J. Boyer, E. Weinman, Wei Wang, 2010, The Journal of Biological Chemistry.

Overexpression of transforming growth factor-alpha alters differentiation of gastric cell lineages.

R. Coffey, I. Modlin, C. Soroka, 1996, Digestive diseases and sciences.

Taurolithocholic Acid Exerts Cholestatic Effects via Phosphatidylinositol 3-Kinase-dependent Mechanisms in Perfused Rat Livers and Rat Hepatocyte Couplets*

J. Boyer, U. Beuers, G. Paumgartner, 2003, The Journal of Biological Chemistry.

Characterization of a novel heparan sulfate proteoglycan found in the extracellular matrix of liver sinusoids and basement membranes

M. Farquhar, C. Soroka, M. G. Farquhar, 1991, The Journal of cell biology.

Degradation of the bile salt export pump at endoplasmic reticulum in progressive familial intrahepatic cholestasis type II

J. Boyer, M. Hochstrasser, N. Wei, 2008, Hepatology.

Basement membrane heparan sulfate proteoglycan is the main proteoglycan synthesized by glomerular epithelial cells in culture.

G. Striker, J. Stow, M. Farquhar, 1989, The American journal of pathology.

A comparison of gene expression in mouse liver and kidney in obstructive cholestasis utilizing high-density oligonucleotide microarray technology.

J. Boyer, A. Lin, C. Soroka, 2006, World journal of gastroenterology.

Overexpression of transforming growth factor-α alters differentiation of gastric cell lineages

R. Coffey, J. Goldenring, I. Modlin, 1996, Digestive Diseases and Sciences.

Hepatic NFAT signaling regulates the expression of inflammatory cytokines in cholestasis

J. Boyer, C. Soroka, S. Cai, 2020, bioRxiv.

Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice.

J. Boyer, C. Soroka, S. Cai, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Co-distribution of calmodulin-dependent protein kinase II and inositol trisphosphate receptors in an apical domain of gastrointestinal mucosal cells.

J. Goldenring, C. Soroka, A. Maranto, 1996, Journal of Histochemistry and Cytochemistry.

Immunogenicity of intestinal basement membrane

M. Weiser, B. Albini, C. Soroka, 1984, Survey of immunologic research.

Enterochromaffin‐like Cell Pathobiology of Mastomys

Laura H. Tang, I. Modlin, G. Lawton, 1994, Annals of the New York Academy of Sciences.

Evidence for a regulatory role for histamine in gastric enterochromaffin-like cell proliferation induced by hypergastrinemia.

I. Modlin, J. Goldenring, M. Kidd, 1996, Digestion.

Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat.

J. Boyer, K. Setchell, F. Azzaroli, 2001, Gastroenterology.

Bile formation and Secretion: An update.

J. Boyer, C. Soroka, 2021, Journal of hepatology.

HEPATIC AND EXTRAHEPATIC SYNTHESIS AND DISPOSITION OF DINITROPHENYL-S-GLUTATHIONE IN BILE DUCT-LIGATED RATS

J. Boyer, C. Soroka, S. Cai, 2006, Drug Metabolism and Disposition.

Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid–fed mouse model of cholestasis

J. Boyer, L. Hagey, C. Soroka, 2016, Hepatology.

OSTα‐OSTβ: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

P. Dawson, J. Boyer, N. Ballatori, 2005 .

Hepatic sequestration and modulation of the canalicular transport of the organic cation, daunorubicin, in the rat

J. Boyer, C. Soroka, L. Rios-Velez, 1999, Hepatology.

Role of Breast Cancer Resistance Protein in the Adaptive Response to Cholestasis

J. Boyer, C. Soroka, A. Mennone, 2010, Drug Metabolism and Disposition.

Mrp4−/− mice have an impaired cytoprotective response in obstructive cholestasis

J. Boyer, J. Schuetz, M. Adachi, 2006, Hepatology.

A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease

J. Boyer, A. Amsterdam, K. Sadler, 2005, Development.

Molecular characterization of a multidrug resistance-associated protein, Mrp2, from the little skate.

J. Boyer, N. Ballatori, C. Soroka, 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

Nuclear receptors RXRα:RARα are repressors for human MRP3 expression

J. Boyer, L. Denson, Shuhua Xu, 2007 .

MOLECULAR CHARACTERIZATION OF A MULTIDRUG RESISTANCE ASSOCIATED PROTEIN FROM THE LITTLE SKATE , RAJA ERINACEA

J. Boyer, N. Ballatori, C. Soroka, 2002 .

EGF receptor activation stimulates endogenous gastrin gene expression in canine G cells and human gastric cell cultures.

J. Merchant, C. Soroka, J. D. Valle, 1997, The Journal of clinical investigation.

Characterization of Parietal Cell Functional Morphology Utilizing Isolated Gastric Gland Perfusion, Atomic Force and Confocal Microscopy

W. Boron, J. Geibel, J. Goldenring, 1994 .

Identification of Functionally Distinct Na-HCO3 Co-Transporters in Colon

Peter Geibel, J. Geibel, C. Barmeyer, 2013, PloS one.

Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat.

J. Boyer, J. Miquel, F. Suchy, 2003, Journal of hepatology.

A cholecystohepatic shunt pathway: does the gallbladder protect the liver?

J. Boyer, C. Soroka, 2012, Gastroenterology.

Characterization of membrane and cytoskeletal compartments in cultured parietal cells: immunofluorescence and confocal microscopic examination.

J. Goldenring, I. Modlin, C. Soroka, 1993, European journal of cell biology.

Sorting of rat liver and ileal sodium-dependent bile acid transporters in polarized epithelial cells.

F. Suchy, A. Sun, M. Ananthanarayanan, 1998, The American journal of physiology.

Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies.

J. Boyer, C. Soroka, D. Assis, 2019, Methods in molecular biology.

Bile‐Derived Organoids From Patients With Primary Sclerosing Cholangitis Recapitulate Their Inflammatory Immune Profile

J. Boyer, Ariel Jaffe, C. Soroka, 2019, Hepatology.

Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes

J. Boyer, U. Beuers, G. Kullak-Ublick, 1999, Hepatology.

Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice.

J. Boyer, Yuhuan Luo, C. Soroka, 2014, Journal of hepatology.

Human Vascularized Bile Duct-on-a Chip: A multi-cellular micro-physiological system for studying Primary Sclerosing Cholangitis

J. Boyer, R. Wells, Chengyang Liu, 2023, bioRxiv.

Role of Biliary Organoids in Cholestasis Research and Regenerative Medicine

J. Boyer, C. Soroka, D. Assis, 2021, Seminars in Liver Disease.

Na+/H+ exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury

J. Boyer, E. Weinman, L. Hagey, 2015, Hepatology.

A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization

J. Boyer, F. Suchy, A. Sun, 2016, PloS one.

N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta

J. Boyer, P. Lam, Shuhua Xu, 2008, BMC Cell Biology.

Histamine as an intermediate growth factor in genesis of gastric ECLomas associated with hypergastrinemia in mastomys

J. Goldenring, O. Nilsson, I. Modlin, 1994, Digestive Diseases and Sciences.

Aryl hydrocarbon receptor and NF-E 2-related factor 2 are key regulators of human MRP 4 expression

J. Boyer, Shuhua Xu, C. Soroka, 2010 .

export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases Levels of plasma membrane expression in progressive and benign mutations of the bile salt

C. Trautwein, F. Lammert, H. Denk, 2007 .