Nikhil Gadewal

发表

HISTome2: a database of histone proteins, modifiers for multiple organisms and epidrugs

Sanjay Gupta, S. Shah, Tushar Mandloi, 2020, Epigenetics & Chromatin.

Structural and biophysical properties of h-FANCI ARM repeat protein

Nikhil Gadewal, A. Varma, H. Misra, 2017, Journal of biomolecular structure & dynamics.

Understanding quasi-apoptosis of the most numerous enucleated components of blood needs detailed molecular autopsy

Nikhil Gadewal, R. Govekar, G. Gusev, 2017, Ageing Research Reviews.

Seminal role of deletion of amino acid residues in H1-S2 and S-loop regions in eukaryotic β-tubulin investigated from docking and dynamics perspective.

Nikhil Gadewal, C. Selvaa Kumar, Sudheer M. M. Mohammed, 2015, Journal of theoretical biology.

Role of Phosphorylation and Hyperphosphorylation of Tau in Its Interaction with βα Dimeric Tubulin Studied from a Bioinformatics Perspective

R. Chaudhary, Nikhil Gadewal, D. Dasgupta, 2020, Avicenna journal of medical biotechnology.

Design and synthesis of thiadiazolo-carboxamide bridged β-carboline-indole hybrids: DNA intercalative topo-IIα inhibition with promising antiproliferative activity

U. Lakshmi, N. Shankaraiah, Sravani Sana, 2020, Bioorganic Chemistry.

Pathogenicity of Mutations Discovered in BRCA1 BRCT Domains is Characterized by Destabilizing the Hydrophobic Interactions

Nikhil Gadewal, A. Varma, D. Badgujar, 2012 .

Restoration of miR-30a expression inhibits growth, tumorigenicity of medulloblastoma cells accompanied by autophagy inhibition.

T. Gupta, A. Moiyadi, A. Goel, 2017, Biochemical and biophysical research communications.

Proteomic profiling of cancer of the gingivo‐buccal complex: Identification of new differentially expressed markers

Sadhana Kannan, Nikhil Gadewal, Ravi Sirdeshmukh, 2009, Proteomics. Clinical applications.

ARID2 suppression promotes tumor progression and upregulates cytokeratin 8, 18 and β-4 integrin expression in TP53-mutated tobacco-related oral cancer and has prognostic implications.

R. Sarin, P. Shukla, Nikhil Gadewal, 2022, Cancer gene therapy.

Understanding the binding affinities between SFRP1 CRD , SFRP1 Netrin , Wnt 5B and frizzled receptors 2, 3 and 7 using MD simulations

R. Joshi, Shruti Koulgi, U. Sonavane, 2021, Journal of biomolecular structure & dynamics.

Design, synthesis and anticancer studies of novel aminobenzazolyl pyrimidines as tyrosine kinase inhibitors.

Sonali G. Thorat, R. Chikhale, Nikhil Gadewal, 2018, Bioorganic chemistry.

6-Shogaol Exhibits Anti-viral and Anti-inflammatory Activity in COVID-19-Associated Inflammation by Regulating NLRP3 Inflammasomes

S. Chattopadhyay, P. Mamidi, S. Mukherjee, 2023, ACS omega.

Identification of Leads from Marine Seaweeds against Human β-tubulin

Nikhil Gadewal, C. SelvaaKumar, Sudheer M. M. Mohammed, 2012 .

HIstome—a relational knowledgebase of human histone proteins and histone modifying enzymes

Sanjay Gupta, Satyajeet P. Khare, Farhat Habib, 2011, Nucleic Acids Res..

Biophysical evaluation to categorize pathogenicity of cancer-predisposing mutations identified in the BARD1 BRCT domain

N. S. Kumar, Nikhil Gadewal, A. Varma, 2018, RSC advances.

Targeting Pim-1 kinase for potential drug-development

Ashok Varma, Nikhil Gadewal, Nikhil Gadewal, 2012, Int. J. Comput. Biol. Drug Des..

Allosteric Regulation of Serine Protease HtrA2 through Novel Non-Canonical Substrate Binding Pocket

Nitu Singh, Nikhil Gadewal, G. M. Sastry, 2013, PloS one.

Molecular Modeling of Differentially Phosphorylated Serine 10 and Acetylated lysine 9/14 of Histone H3 Regulates their Interactions with 14-3-3ζ, MSK1, and MKP1

Sanjay Gupta, Nikhil Gadewal, A. Varma, 2013, Bioinformatics and biology insights.

β-Lactoglobulin-gold nanoparticles interface and its interaction with some anticancer drugs – an approach for targeted drug delivery

Arti R. Hole, C. Krishna, Nikhil Gadewal, 2021, Journal of biomolecular structure & dynamics.

Functional Basis and Biophysical Approaches to Characterize the C-Terminal Domain of Human—Ribosomal S6 Kinases-3

Nikhil Gadewal, A. Varma, M. Hosur, 2016, Cell Biochemistry and Biophysics.

Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas

V. Ramaswamy, T. Gupta, A. Moiyadi, 2019, Acta neuropathologica communications.

In silico analysis of peptide binding features of HLA-B*4006.

Nikhil Gadewal, N. Joshi, 2012, Indian journal of experimental biology.

Histone H2A isoforms: Potential implications in epigenome plasticity and diseases in eukaryotes

M. Rashid, Nikhil Gadewal, Tripti Verma, 2020, Journal of Biosciences.

Histone H2A isoforms: Potential implications in epigenome plasticity and diseases in eukaryotes

Sanjay Gupta, S. Shah, M. Rashid, 2020, Journal of Biosciences.

Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50

S. Nachimuthu, Nikhil Gadewal, A. Varma, 2017, Scientific Reports.

Multimodal approach to explore the pathogenicity of BARD1, ARG 658 CYS, and ILE 738 VAL mutants

Vikrant, N. S. Kumar, Nikhil Gadewal, 2016, Journal of biomolecular structure & dynamics.

Bioinformatics Based Understanding of Effect of Mutations in the Human β Tubulin Outside Drug Binding Sites and its Significance in Drug Resistance

Nikhil Gadewal, C. SelvaaKumar, D. Dasgupta, 2018 .

Forging of nicotine for the effective management of diabetic wounds: A hybrid of scaffold hopping and molecular dynamics simulation approaches

Nikhil Gadewal, R. Bhandare, A. Shaik, 2021, Arabian Journal of Chemistry.

Phosphorylation of deinococcal RecA affects its structural and functional dynamics implicated for its roles in radioresistance of Deinococcus radiodurans

D. Sharma, Nikhil Gadewal, A. Varma, 2020, Journal of biomolecular structure & dynamics.

Downregulation of ARID1B, a tumor-suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways.

T. Gupta, A. Goel, R. Jalali, 2021, Human molecular genetics.

Conserved residues at the MAPKs binding interfaces that regulate transcriptional machinery

Nikhil Gadewal, Satish Kumar, Ulka Sawant, 2015, Journal of biomolecular structure & dynamics.

miRNA–mRNA Profiling Reveals Prognostic Impact of SMC1A Expression in Acute Myeloid Leukemia

Nikhil Gadewal, A. Varma, S. Hasan, 2020, Oncology research.

Functional Basis and Biophysical Approaches to Characterize the C-Terminal Domain of Human—Ribosomal S6 Kinases-3

Nikhil Gadewal, A. Varma, M. Hosur, 2016, Cell Biochemistry and Biophysics.

Database and interaction network of genes involved in oral cancer: Version II

Nikhil Sureshkumar Gadewal, Surekha Mahesh Zingde, S. Zingde, 2011, Bioinformation.

Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas

V. Ramaswamy, T. Gupta, A. Moiyadi, 2019, Acta Neuropathologica Communications.

Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics

R. Joshi, U. Sonavane, Sanjay Gupta, 2017, Epigenetics & Chromatin.

Insights into the flexibility of the T3 loop and GTPase activating protein (GAP) domain of dimeric α and β tubulins from a molecular dynamics perspective

Nikhil Gadewal, C SelvaaKumar, Rajan kumar Choudhary, 2019, Comput. Biol. Chem..

The effect of p14ARF and YY1 peptides in MDM2-p53 mediated oncogenic pathway: An in silico perspective

Nikhil Gadewal, Nikita Soni, Shine Devarajan, 2018, 2018 International Conference on Bioinformatics and Systems Biology (BSB).

Conserved residues at the MAPKs binding interfaces that regulate transcriptional machinery

Nikhil Gadewal, Satish Kumar, Ulka Sawant, 2015, Journal of biomolecular structure & dynamics.

Pathogenic HER3 dimerization domain mutations create a structural bias towards un-conventional EGFR-HER3 signalling axis in breast cancer.

Nikhil Gadewal, Abhijit De, Pranay Dey, 2023, International journal of biological macromolecules.

Studies of protein-protein interactions in Fanconi anemia pathway to unravel the DNA interstrand crosslink repair mechanism.

Nikhil Gadewal, A. Varma, H. Misra, 2017, International journal of biological macromolecules.

Medulloblastoma-associated DDX3X mutants are oncogenic having a defect in translation-promoting activity but functional in stress granule formation and interferon signaling

Nikhil Gadewal, N. Shirsat, Satishkumar Vishram Singh, 2023, bioRxiv.