G. Colonna‐Romano

C. Caruso, D. Lio, G. Candore, 2002, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Inflammation, Longevity, and Cardiovascular Diseases

C. Caruso, D. Lio, S. Vasto, 2006, Annals of the New York Academy of Sciences.

Can Alzheimer disease be a form of type 3 diabetes?

Giuseppina Candore, R. Monastero, C. Caruso, 2012, Rejuvenation research.

Understanding ageing: Biomedical and bioengineering approaches, the immunologic view

S. Vasto, G. Colonna‐Romano, Sonya Vasto, 2008, Immunity & Ageing.

Immunosenescence and anti-immunosenescence therapies: the case of probiotics.

C. Caruso, D. Lio, S. Vasto, 2008, Rejuvenation research.

B cell immunosenescence in the elderly and in centenarians.

C. Caruso, D. Lio, G. Candore, 2008, Rejuvenation research.

Inflammation, genes and zinc in ageing and age-related diseases

C. Caruso, D. Lio, S. Vasto, 2006, Biogerontology.

Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes'.

G. Pawelec, C. Caruso, D. Lio, 2002, Trends in immunology.

The Increase of the Pro-inflammatory Double Negative (IgD−CD27−) B Cell Subset Is Related to the Severity of Alzheimer’s Disease

C. Caruso, G. Colonna‐Romano, M. Bulati, 2019, Handbook of Immunosenescence.

The Increase of the Pro-inflammatory Double Negative (IgD−CD27−) B Cell Subset Is Related to the Severity of Alzheimer’s Disease

C. Caruso, G. Colonna‐Romano, M. Bulati, 2019, Handbook of Immunosenescence.

Centenarian offspring: a model for understanding longevity.

C. Caruso, D. Lio, C. Balistreri, 2013, Current vascular pharmacology.

Evidence for less marked potential signs of T-cell immunosenescence in centenarian offspring than in the general age-matched population.

G. Pawelec, C. Caruso, S. Buffa, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Expression of calpain-calpastatin system (CCS) member proteins in human lymphocytes of young and elderly individuals; pilot baseline data for the CALPACENT project

C. Caruso, J. Foerster, S. Buffa, 2013, Immunity & Ageing.

Association between HFE mutations and acute myocardial infarction: a study in patients from Northern and Southern Italy.

F. Licastro, A. Branzi, M. Chiappelli, 2003, Blood cells, molecules & diseases.

Alpha1-antitrypsin heterozygosity plays a positive role in attainment of longevity

C. Franceschi, G. Paolisso, C. Caruso, 2007, Biogerontology.

Association between the HFE mutations and unsuccessful ageing: a study in Alzheimer's disease patients from Northern Italy

C. Franceschi, F. Licastro, L. Grimaldi, 2003, Mechanisms of Ageing and Development.

Frequency of the HFE gene mutations in five Italian populations.

C. Caruso, D. Lio, A. Amoroso, 2002, Blood cells, molecules & diseases.

A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people

C. Caruso, D. Lio, G. Candore, 2009, Mechanisms of Ageing and Development.

A novel B cell population revealed by a CD38/CD24 gating strategy: CD38−CD24− B cells in centenarian offspring and elderly people

G. Pawelec, C. Caruso, S. Buffa, 2013, AGE.

Role of persistent CMV infection in configuring T cell immunity in the elderly

G. Pawelec, C. Caruso, A. Larbi, 2007, Immunity & Ageing.

B cell immunosenescence: different features of naive and memory B cells in elderly

C. Caruso, S. Buffa, G. Candore, 2011, Biogerontology.

B cells in the aged: CD27, CD5, and CD40 expression

C. Caruso, D. Lio, M. Malaguarnera, 2003, Mechanisms of Ageing and Development.

Trafficking phenotype and production of granzyme B by double negative B cells (IgG+IgD−CD27−) in the elderly

C. Caruso, D. Lio, S. Buffa, 2014, Experimental Gerontology.

Traf fi cking phenotype and production of granzyme B by double negative B cells ( IgG + IgD − CD 27 − ) in the elderly

C. Caruso, D. Lio, S. Buffa, 2014 .

Opposite Role of Pro‐Inflammatory Alleles in Acute Myocardial Infarction and Longevity

C. Franceschi, G. Paolisso, C. Caruso, 2006, Annals of the New York Academy of Sciences.

A Study of Serum Immunoglobulin Levels in Elderly Persons That Provides New Insights into B Cell Immunosenescence

C. Franceschi, C. Caruso, D. Lio, 2006, Annals of the New York Academy of Sciences.

Memory B cell subpopulations in the aged.

C. Caruso, D. Lio, G. Candore, 2006, Rejuvenation research.

Association between the HFE mutations and longevity: a study in Sardinian population

C. Franceschi, C. Caruso, D. Lio, 2003, Mechanisms of Ageing and Development.

Association between the HLA-DR alleles and longevity: a study in Sardinian population

L. Ferrucci, C. Franceschi, C. Caruso, 2003, Experimental Gerontology.

Analysis of hemochromatosis gene mutations in the Sicilian population: implications for survival and longevity.

C. Caruso, D. Lio, M. Malaguarnera, 2002, Archives of gerontology and geriatrics. Supplement.

Growth factors and IL-17 in hereditary angioedema

G. Colonna‐Romano, E. Cillari, S. Milano, 2016, Clinical and Experimental Medicine.

Nutraceutical properties of extra-virgin olive oil: a natural remedy for age-related disease?

C. Caruso, S. Vasto, G. Accardi, 2014, Rejuvenation research.

HLA and KIR frequencies in Sicilian Centenarians.

C. Caruso, D. Lio, D. Nuzzo, 2010, Rejuvenation research.

A Typical Immune T/B Subset Profile Characterizes Bicuspid Aortic Valve: In an Old Status?

D. Lio, G. Ruvolo, S. Sciarretta, 2018, Oxidative medicine and cellular longevity.

Systematic review by meta-analyses on the possible role of TNF-α polymorphisms in association with Alzheimer's disease

C. Franceschi, F. Licastro, C. Caruso, 2009, Brain Research Reviews.

Tumor necrosis factor-α−308A/G polymorphism is associated with age at onset of Alzheimer's disease

G. Annoni, F. Licastro, C. Caruso, 2006, Mechanisms of Ageing and Development.

SARS CoV2 infection _The longevity study perspectives

C. Caruso, D. Lio, C. Balistreri, 2021, Ageing Research Reviews.

Impairment of gamma/delta T lymphocytes in elderly: implications for immunosenescence

C. Caruso, D. Lio, G. Candore, 2004, Experimental Gerontology.

Looking for Immunological Risk Genotypes

C. Caruso, D. Lio, G. Candore, 2004, Annals of the New York Academy of Sciences.

Gamma/delta T lymphocytes are affected in the elderly

C. Caruso, D. Lio, G. Candore, 2002, Experimental Gerontology.

Immunological and immunogenetic markers of successful and unsuccessful ageing

C. Caruso, D. Lio, G. Candore, 2002 .

Inflammation, genetic background and longevity

C. Caruso, G. Candore, G. Colonna‐Romano, 2010, Biogerontology.

Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 −1082 promoter SNP and its interaction with TNF-α −308 promoter SNP

C. Franceschi, C. Caruso, D. Lio, 2003, Journal of medical genetics.

Opposite effects of interleukin 10 common gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is protective against coronary heart disease

C. Franceschi, F. Licastro, A. Branzi, 2004, Journal of Medical Genetics.

From lymphopoiesis to plasma cells differentiation, the age-related modifications of B cell compartment are influenced by “inflamm-ageing”

C. Caruso, G. Colonna‐Romano, M. Bulati, 2017, Ageing Research Reviews.

Double negative (IgG+IgD-CD27-) B cells are increased in a cohort of moderate-severe Alzheimer's disease patients and show a pro-inflammatory trafficking receptor phenotype.

R. Monastero, C. Caruso, S. Buffa, 2015, Journal of Alzheimer's disease : JAD.

Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease

C. Franceschi, F. Licastro, L. Grimaldi, 2003, Genes and Immunity.

Gender-specific association between −1082 IL-10 promoter polymorphism and longevity

L Scola, D Lio, C. Franceschi, 2002, Genes and Immunity.

Major Histocompatibility Complex Polymorphisms and Ageing

C. Caruso, D. Lio, G. Candore, 2004 .

Role of TLR Polymorphisms in Immunosenescence

C. Caruso, D. Lio, S. Vasto, 2009 .

Analysis of HLA-DRB1,DQA1,DQB1 haplotypes in Sardinian centenarians

L. Ferrucci, C. Franceschi, C. Caruso, 2008, Experimental Gerontology.

Inflammation, ageing and cancer

C. Caruso, D. Lio, G. Carruba, 2009, Mechanisms of Ageing and Development.

Impact of CMV and EBV seropositivity on CD8 T lymphocytes in an old population from West-Sicily

G. Pawelec, C. Caruso, D. Lio, 2007, Experimental Gerontology.

Role of TGF-β Pathway Polymorphisms in Sporadic Thoracic Aortic Aneurysm: rs900 TGF-β2 Is a Marker of Differential Gender Susceptibility

D. Lio, L. Vaccarino, G. Ruvolo, 2014, Mediators of inflammation.

Polymorphisms of pro-inflammatory genes and prostate cancer risk: a pharmacogenomic approach

C. Caruso, D. Lio, G. Carruba, 2009, Cancer Immunology, Immunotherapy.

NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

D. Lio, C. Balistreri, G. Accardi, 2013, Immunity & Ageing.

SARS CoV2 infection _The longevity study perspectives

C. Caruso, D. Lio, C. Balistreri, 2021, Ageing Research Reviews.

A pilot study on prostate cancer risk and pro-inflammatory genotypes: pathophysiology and therapeutic implications.

C. Caruso, D. Lio, G. Carruba, 2010, Current pharmaceutical design.

TLR4 Polymorphisms and Ageing: Implications for the Pathophysiology of Age-Related Diseases

C. Caruso, D. Lio, C. Balistreri, 2009, Journal of Clinical Immunology.

C. Franceschi, C. Caruso, D. Lio, 2010, Current pharmaceutical design.

Immune profiling of Alzheimer patients

G. Pawelec, C. Caruso, A. Larbi, 2012, Journal of Neuroimmunology.

C. Caruso, D. Lio, S. Vasto, 2010, Rejuvenation research.

Pathogenesis of autoimmune diseases associated with 8.1 ancestral haplotype: a genetically determined defect of C4 influences immunological parameters of healthy carriers of the haplotype.

M. Cuccia, C. Caruso, D. Lio, 2003, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Immunogenetics, Gender, and Longevity

C. Franceschi, C. Caruso, D. Lio, 2006, Annals of the New York Academy of Sciences.

Analysis of HLA-DQA, HLA-DQB frequencies in a group of Sardinian centenarians.

L. Ferrucci, C. Franceschi, C. Caruso, 2006, Rejuvenation research.

Major histocompatibility complex and sporadic Alzheimer's disease: a critical reappraisal

C. Caruso, D. Lio, C. Balistreri, 2004, Experimental Gerontology.

B Cells in Centenarians and Their Offspring

C. Caruso, G. Colonna‐Romano, M. Bulati, 2018 .

Double negative (CD19+IgG+IgD-CD27-) B lymphocytes: a new insight from telomerase in healthy elderly, in centenarian offspring and in Alzheimer's disease patients.

R. Monastero, C. Caruso, C. Balistreri, 2014, Immunology letters.

SARS CoV2 infection _The longevity study perspectives

C. Caruso, D. Lio, C. Balistreri, 2021, Ageing Research Reviews.

Genetics of longevity. data from the studies on Sicilian centenarians

D. Lio, L. Vaccarino, C. Balistreri, 2012, Immunity & Ageing.

Immune pro fi ling of Alzheimer patients

G. Pawelec, C. Caruso, A. Larbi, 2012 .

Inflammatory networks in ageing, age-related diseases and longevity

C. Caruso, D. Lio, D. Nuzzo, 2007, Mechanisms of Ageing and Development.

Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians

L. Ferrucci, C. Franceschi, C. Caruso, 2004, Aging clinical and experimental research.

NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies

D. Lio, C. Balistreri, G. Accardi, 2013, Immunity & Ageing.

Biology of longevity: role of the innate immune system.

C. Caruso, D. Lio, D. Nuzzo, 2006, Rejuvenation research.

Role of Toll-like receptor 4 in acute myocardial infarction and longevity.

C. Franceschi, C. Caruso, D. Lio, 2004, JAMA.

CCR5 Proinflammatory Allele in Prostate Cancer Risk

C. Caruso, D. Lio, G. Carruba, 2009, Annals of the New York Academy of Sciences.

CCR 5 Proinflammatory Allele in Prostate Cancer Risk A Pilot Study in Patients and Centenarians from Sicily

C. Caruso, D. Lio, G. Carruba, 2009 .

Polymorphisms of pro-inflammatory genes and Alzheimer's disease risk: A pharmacogenomic approach

F. Licastro, M. Chiappelli, C. Caruso, 2007, Mechanisms of Ageing and Development.

Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of IFN-γ gene in Alzheimer’s disease patients

C. Franceschi, F. Licastro, L. Grimaldi, 2003, Aging clinical and experimental research.

Report from the second cytomegalovirus and immunosenescence workshop

S. J. Griffiths, D. Melzer, P. Klenerman, 2011, Immunity & Ageing.

Inflammation, genes and zinc in Alzheimer's disease

Domenico Lio, Carmela Rita Balistreri, Giuseppina Candore, 2008, Brain Research Reviews.

Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: therapeutic implications.

C. Caruso, D. Lio, S. Vasto, 2010, Rejuvenation research.

Systemic immune responses in Alzheimer's disease: in vitro mononuclear cell activation and cytokine production.

M. Barbagallo, C. Caruso, D. Lio, 2010, Journal of Alzheimer's disease : JAD.

Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: implication for pharmacogenomics.

F. Licastro, M. Chiappelli, C. Caruso, 2010, Journal of Alzheimer's disease : JAD.

Glucose-induced loss of glycosyl-phosphatidylinositol-anchored membrane regulators of complement activation (CD59, CD55) by in vitro cultured human umbilical vein endothelial cells

G. Caimi, A. Ferrante, G. Colonna‐Romano, 2000, Diabetologia.

Is the mean blood leukocyte telomere length a predictor for sporadic thoracic aortic aneurysm? Data from a preliminary study.

C. Balistreri, C. Pisano, K. Fattouch, 2012, Rejuvenation research.

Association between platelet endothelial cellular adhesion molecule 1 (PECAM-1/CD31) polymorphisms and acute myocardial infarction: a study in patients from Sicily.

C. Caruso, D. Lio, L. Cavallone, 2004, European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics.

Role of TLR4 Receptor Polymorphisms in Boutonneuse Fever

C. Franceschi, C. Caruso, D. Lio, 2005, International journal of immunopathology and pharmacology.

LPS-mediated production of pro/anti-inflammatory cytokines and eicosanoids in whole blood samples: Biological effects of +896A/G TLR4 polymorphism in a Sicilian population of healthy subjects

C. Caruso, D. Lio, C. Balistreri, 2011, Mechanisms of Ageing and Development.

Mechanisms of immunosenescence

G. Pawelec, C. Caruso, D. Kipling, 2009, Immunity & Ageing.

Association between the interleukin-1β polymorphisms and Alzheimer's disease: A systematic review and meta-analysis

Antonella Plaia, Claudio Franceschi, Francesco Lescai, 2008, Brain Research Reviews.

Expression of calpain-calpastatin system (CCS) member proteins in human lymphocytes of young and elderly individuals; pilot baseline data for the CALPACENT project

C. Caruso, J. Foerster, S. Buffa, 2013, Immunity & Ageing.

Prevalence of non organ-specific autoantibodies in healthy centenarians.

C. Caruso, D. Lio, M. Malaguarnera, 2002, Archives of gerontology and geriatrics. Supplement.