Z. Spolarics

发表

Augmented resistance to oxidative stress in fatty rat livers induced by a short-term sucrose-rich diet.

Z. Spolarics, M. Meyenhofer, 2000, Biochimica et biophysica acta.

Influence of storage on red blood cell rheological properties.

E. Deitch, Z. Spolarics, S. Zaets, 2002, The Journal of surgical research.

Appearance of an erythrocyte population with decreased deformability and hemoglobin content following sepsis.

E. Deitch, M. Condon, Z. Spolarics, 2003, American journal of physiology. Heart and circulatory physiology.

Methemoglobin is a potent activator of endothelial cells by stimulating IL-6 and IL-8 production and E-selectin membrane expression.

Z. Spolarics, Xueying Liu, 2003, American journal of physiology. Cell physiology.

Ecto-5′-Nucleotidase (CD73) Decreases Mortality and Organ Injury in Sepsis

E. Deitch, L. Thompson, Z. Nemeth, 2011, The Journal of Immunology.

Complement activates Kupffer cells and neutrophils during reperfusion after hepatic ischemia.

H. Jaeschke, J. Spitzer, A. Farhood, 1993, The American journal of physiology.

Augmented erythrocyte band-3 phosphorylation in septic mice.

E. Deitch, M. Condon, Z. Spolarics, 2007, Biochimica et biophysica acta.

Augmented IL‐10 production and redox‐dependent signaling pathways in glucose‐6‐phosphate dehydrogenase‐deficient mouse peritoneal macrophages

E. Deitch, Z. Spolarics, Jeanette Wilmanski, 2005, Journal of leukocyte biology.

Acute alcohol administration attenuates insulin-mediated glucose use by skeletal muscle.

J. Spitzer, P. Pekala, C. Dobrescu, 1994, The American journal of physiology.

Intravenous injection of mesenteric lymph produced during hemorrhagic shock decreases RBC deformability in the rat.

E. Deitch, M. Senthil, M. Condon, 2011, The Journal of trauma.

Trauma-Hemorrhagic Shock Induces a CD36-Dependent RBC Endothelial-Adhesive Phenotype

Jacquelyn N. Tomaio, W. Durán, E. Deitch, 2014, Critical care medicine.

X-Linked IRAK1 Polymorphism is Associated with Sex-Related Differences In Polymorphonuclear Granulocyte and Monocyte Activation and Response Variabilities.

D. Livingston, Z. Spolarics, A. Mosenthal, 2020, Shock.

Female X-Chromosome Mosaicism for NOX2 Deficiency Presents Unique Inflammatory Phenotype and Improves Outcome in Polymicrobial Sepsis

E. Deitch, Z. Nemeth, R. Chandra, 2011, The Journal of Immunology.

Polymicrobial Sepsis Phenotype and Improves Outcome in Deficiency Presents Unique Inflammatory Female X-Chromosome Mosaicism for NOX2

E. Deitch, Z. Nemeth, R. Chandra, 2011 .

Effect of high-dose endotoxin on glucose production and utilization.

J. Spitzer, C. Lang, Z. Spolarics, 1993, Metabolism: clinical and experimental.

Monoclonal antibody against the CD18 adhesion molecule stimulates glucose uptake by the liver and hepatic nonparenchymal cells

C. Smith, H. Jaeschke, J. Spitzer, 1993, Hepatology.

Hepatic Responses to Bacterial Endotoxin (LPS)

H. Jaeschke, J. Spitzer, I. Deaciuc, 1993 .

Augmented TNF‐α and IL‐10 production by primed human monocytes following interaction with oxidatively modified autologous erythrocytes

J. Siegel, Z. Spolarics, T. Denny, 2001, Journal of leukocyte biology.

Tumor necrosis factor alpha augments the expression of glucose-6-phosphate dehydrogenase in rat hepatic endothelial and Kupffer cells.

Z. Spolarics, J. X. Wu, 1997, Life sciences.

Antineutrophil monoclonal antibody (1F12) alters superoxide anion release by neutrophils and Kupffer cells

C. Smith, H. Jaeschke, J. Spitzer, 1994, Journal of leukocyte biology.

Glutamine and fatty acid oxidation are the main sources of energy for Kupffer and endothelial cells.

J. Spitzer, C. Lang, G. Bagby, 1991, The American journal of physiology.

CB2 Cannabinoid Receptors Contribute to Bacterial Invasion and Mortality in Polymicrobial Sepsis

E. Deitch, Z. Nemeth, P. Pacher, 2009, PloS one.

Excessive Inflammation Sepsis-Induced Mortality by Dampening Adenosine Receptors Protect against 2BA

E. Vizi, E. Deitch, Z. Nemeth, 2010 .

Endotoxin stimulates hydrogen peroxide detoxifying activity in rat hepatic endothelial cells

Z. Spolarics, D. Stein, Z. Garcia, 1996, Hepatology.

IRAK1-Dependent Signaling Mediates Mortality in Polymicrobial Sepsis

E. Deitch, James A. Thomas, Z. Nemeth, 2013, Inflammation.

Mortality and Organ Injury in Sepsis -Nucleotidase (CD73) Decreases ¢ Ecto-5

E. Deitch, L. Thompson, Z. Nemeth, 2022 .

In vivo latex phagocytosis primes the Kupffer cells and hepatic neutrophils to generate superoxide anion

Á. Schuler, J. Spitzer, Z. Spolarics, 1992, Journal of leukocyte biology.

Comparison of biochemical properties of liver arginase from streptozocin-induced diabetic and control mice.

Z. Spolarics, J. Bond, 1989, Archives of biochemistry and biophysics.

Multiple molecular forms of mouse liver arginase.

Z. Spolarics, J. Bond, 1988, Archives of biochemistry and biophysics.

Endotoxemia, pentose cycle, and the oxidant/antioxidant balance in the hepatic sinusoid

Z. Spolarics, Zoltán Spolarics, 1998, Journal of leukocyte biology.

Red blood cell dysfunction in septic glucose-6-phosphate dehydrogenase-deficient mice.

E. Deitch, M. Condon, Z. Spolarics, 2004, American journal of physiology. Heart and circulatory physiology.

Red blood cell damage after trauma-hemorrhage is modulated by gender.

E. Deitch, Z. Spolarics, S. Zaets, 2004, The Journal of trauma.

Endotoxemia down‐regulates bone marrow lymphopoiesis but stimulates myelopoiesis: the effect of G6PD deficiency

E. Deitch, R. Chandra, Z. Spolarics, 2008, Journal of leukocyte biology.

Reversible inhibition of RNA synthesis and irreversible inhibition of protein synthesis by D-galactosamine in isolated mouse hepatocytes

J. Mandl, Z. Spolarics, K. Mészáros, 1982, Molecular and Cellular Biochemistry.

Association of thrombin, plasmin, thrombin-antithrombin III complex and plasmin-antithrombin III complex with isolated hepatocytes.

J. Mandl, M. Kalapos, Z. Spolarics, 1989, Biochimica et biophysica acta.

Changes of prostacyclin and thromboxane synthesis in the course of mouse liver perfusion. Stimulated thromboxane A2 synthesis of freshly prepared isolated mouse hepatocytes.

J. Mandl, G. Bánhegyi, Z. Spolarics, 1989, Prostaglandins, leukotrienes, and essential fatty acids.

cAMP dependent inhibition of thromboxane A2, prostacyclin and PGF2 alpha synthesis in mouse hepatocytes.

J. Mandl, G. Bánhegyi, Z. Spolarics, 1988, Prostaglandins.

Interaction of thrombin, antithrombin III and their complex with hepatocytes: comparison of the molecular components of human and mouse origin.

J. Mandl, M. Kalapos, Z. Spolarics, 1987, Thrombosis research.

Sphingosine 1-Phosphate Has Dual Functions in the Regulation of Endothelial Cell Permeability and Ca2+ Metabolism

E. Deitch, C. Hauser, K. Itagaki, 2007, Journal of Pharmacology and Experimental Therapeutics.

Kupffer cells play a major role in insulin-mediated hepatic glucose uptake in vivo.

J. Spitzer, C. Lang, Z. Spolarics, 1992, Biochemical and biophysical research communications.

Role of glutathione and catalase in H2O2 detoxification in LPS-activated hepatic endothelial and Kupffer cells.

Z. Spolarics, J. X. Wu, JUN-XI Wu, 1997, The American journal of physiology.

Role of glutathione and catalase in H2O2detoxification in LPS-activated hepatic endothelial and Kupffer cells.

Z. Spolarics, Jun-Xi Wu, 1997, American journal of physiology. Gastrointestinal and liver physiology.

Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients.

J. Siegel, E. Deitch, Z. Spolarics, 2003, Critical care medicine.

Sphingosine 1-Phosphate Has Dual Functions in the Regulation of Endothelial Cell Permeability and Ca Metabolism

E. Deitch, C. Hauser, K. Itagaki, 2007 .

Association of α2-macroglobulin-thrombin and α2-macroglobulin-plasmin complexes with isolated hepatocytes

J. Mandl, Z. Spolarics, I. Horváth, 1985 .

Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats

H. Jaeschke, J. Spitzer, Z. Spolarics, 1992, Journal of leukocyte biology.

Functional inactivation of neutrophils with a Mac‐1 (CD11b/CD18) monoclonal antibody protects against ischemia‐reperfusion injury in rat liver

C. Smith, H. Jaeschke, J. Spitzer, 1993, Hepatology.

Prostanoid synthesis in isolated parenchymal and nonparenchymal mouse liver cells in the presence of arachidonic acid.

J. Mandl, G. Bánhegyi, Z. Spolarics, 1987, Prostaglandins, leukotrienes, and medicine.

Prostaglandin and thromboxane synthesizing activity in isolated murine hepatocytes and nonparenchymal liver cells.

J. Mandl, Z. Spolarics, I. Horváth, 1984, Prostaglandins, leukotrienes, and medicine.

Extracellular ATP protects against sepsis through macrophage P2X7 purinergic receptors by enhancing intracellular bacterial killing

M. Idzko, K. Erdélyi, Z. Nemeth, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

ADENOSINE A2A RECEPTOR INACTIVATION INCREASES SURVIVAL IN POLYMICROBIAL SEPSIS

C. Ledent, E. Deitch, Z. Nemeth, 2006, Journal of immunology.

Directional X Chromosome Skewing of White Blood Cells from Subjects with Heterozygous Mosaicism for the Variant IRAK1 Haplotype

D. Livingston, Z. Spolarics, A. Mosenthal, 2019, Inflammation.

Endotoxin stimulates the expression of glucose‐6‐phosphate dehydrogenase in Kupffer and hepatic endothelial cells

Z. Spolarics, L. Navarro, 1994, Journal of leukocyte biology.

A2B Adenosine Receptors Protect against Sepsis-Induced Mortality by Dampening Excessive Inflammation

E. Vizi, E. Deitch, Z. Nemeth, 2010, The Journal of Immunology.

THE X-FILES OF INFLAMMATION: CELLULAR MOSAICISM OF X-LINKED POLYMORPHIC GENES AND THE FEMALE ADVANTAGE IN THE HOST RESPONSE TO INJURY AND INFECTION

Z. Spolarics, 2007, Shock.

Mesenteric lymph duct ligation decreases red blood cell alterations caused by acute pancreatitis.

D. Mole, E. Deitch, Z. Spolarics, 2005, American journal of surgery.

Tumor necrosis factor-alpha stimulates superoxide anion generation by perfused rat liver and Kupffer cells.

Á. Schuler, J. Spitzer, Z. Spolarics, 1991, The American journal of physiology.

Alcohol administration attenuates LPS-induced expression of inducible nitric oxide synthase in Kupffer and hepatic endothelial cells.

J. Spitzer, J. Kolls, Z. Spolarics, 1993, Biochemical and biophysical research communications.

Trauma-hemorrhagic shock-induced red blood cell damage leads to decreased microcirculatory blood flow*

E. Deitch, Z. Spolarics, S. Zaets, 2009, Critical care medicine.

Effect of Trauma-Hemorrhagic Shock on Red Blood Cell Deformability and Shape

E. Deitch, Z. Spolarics, S. Zaets, 2003, Shock.

Upregulation of glucose metabolism by granulocyte-monocyte colony-stimulating factor.

Á. Schuler, J. Spitzer, C. Lang, 1991, Life sciences.

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function

E. Vizi, C. Ledent, E. Deitch, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Increased incidence of sepsis and altered monocyte functions in severely injured type A− glucose-6-phosphate dehydrogenase-deficient African American trauma patients

J. Siegel, E. Deitch, D. Livingston, 2001, Critical care medicine.

Superoxide generation by Kupffer cells and priming of neutrophils during reperfusion after hepatic ischemia.

H. Jaeschke, J. Spitzer, Z. Spolarics, 1991, Free radical research communications.

Metabolic response of isolated liver cells to in Vivo phagocytic challenge

J. Spitzer, Z. Spolarics, A. Bautista, 1991, Hepatology.

Inherent X-Linked Genetic Variability and Cellular Mosaicism Unique to Females Contribute to Sex-Related Differences in the Innate Immune Response

R. Donnelly, D. Livingston, Z. Spolarics, 2017, Front. Immunol..

Trauma-Induced Acute X Chromosome Skewing in White Blood Cells Represents an Immuno-Modulatory Mechanism Unique to Females and a Likely Contributor to Sex-Based Outcome Differences

R. Donnelly, D. Livingston, Z. Spolarics, 2017, Shock.

Female X-chromosome mosaicism for gp91phox expression diversifies leukocyte responses during endotoxemia

E. Deitch, R. Chandra, Z. Spolarics, 2010, Critical care medicine.

Dopaminergic Control of Inflammation and Glycemia in Sepsis and Diabetes

L. Ulloa, Z. Spolarics, E. Feketeova, 2018, Front. Immunol..

Alterations in hepatic production and peripheral clearance of IGF-I after endotoxin.

A. Kolasa, C. Lang, C. Patlak, 1995, The American journal of physiology.

Attenuated Monocyte Il-10 Production in Glucose-6-Phosphate Dehydrogenase-Deficient Trauma Patients

J. Siegel, E. Deitch, Z. Spolarics, 2002, Shock.

INTERACTIONS BETWEEN BIOLOGICAL SEX AND THE X-LINKED VARIANT IRAK1 HAPLOTYPE IN MODULATING CLINICAL OUTCOME AND CELLULAR PHENOTYPES AFTER TRAUMA

D. Livingston, Z. Spolarics, Yong Qin, 2022, Shock.

In gender-based outcomes, sex hormones may be important but it is in the genes*.

Z. Spolarics, 2014, Critical care medicine.

Acute endotoxin tolerance is accompanied by stimulated glucose use in macrophage rich tissues.

J. Spitzer, Z. Spolarics, 1995, Biochemical and biophysical research communications.

Adenosine A2A Receptor Inactivation Increases Survival in Polymicrobial Sepsis1

C. Ledent, E. Deitch, Z. Nemeth, 2006, The Journal of Immunology.

Adenosine A 2 A Receptor Inactivation Increases Survival in Polymicrobial Sepsis 1

C. Ledent, E. Deitch, Z. Nemeth, 2006 .

DOMINANCE OF HIGH-PRODUCING INTERLEUKIN 6 AND LOW-PRODUCING INTERLEUKIN 10 AND INTERFERON γ ALLELES IN GLUCOSE-6-PHOSPHATE DEHYDROGENASE- DEFICIENT TRAUMA PATIENTS

H. Ford, J. Upperman, C. Kammerer, 2005, Shock.

Uptake of arachidonic acid, arachidic acid, oleic acid and their incorporation into phospholipids and triacylglycerols of isolated murine hepatocytes. Effect of thrombin-antithrombin III complex.

J. Mandl, Z. Spolarics, I. Horváth, 1984, Thrombosis research.

Endotoxin stimulates gene expression of ROS-eliminating pathways in rat hepatic endothelial and Kupffer cells.

Z. Spolarics, 1996, The American journal of physiology.

Augmented glucose use and pentose cycle activity in hepatic endothelial cells after in vivo endotoxemia

J. Spitzer, Z. Spolarics, 1993, Hepatology.

Relationship between oxidative burst activity and CD11b expression in neutrophils and monocytes from healthy individuals: effects of race and gender.

Z. Spolarics, T. Denny, D. Stein, 2001, Cytometry.

Cellular mosaicism for X‐linked polymorphisms and IRAK1 expression presents a distinct phenotype and improves survival following sepsis

R. Donnelly, Z. Nemeth, R. Chandra, 2014, Journal of leukocyte biology.

Victims or Culprits, B Cells May Serve as Markers for Mortality Risk and Targeted Therapy in Sepsis.

Z. Spolarics, 2017, Critical care medicine.

Brief endotoxemia markedly increases expression of GLUT1 glucose transporter in Kupffer, hepatic endothelial and parenchymal cells.

J. Spitzer, P. Pekala, G. Bagby, 1993, Biochemical and Biophysical Research Communications - BBRC.

IRAK1-Dependent Signaling Mediates Mortality in Polymicrobial Sepsis

E. Deitch, Z. Nemeth, R. Chandra, 2013, Inflammation.

Primed pentose cycle activity supports production and elimination of superoxide anion in Kupffer cells from rats treated with endotoxin in vivo.

J. Spitzer, Z. Spolarics, A. Bautista, 1993, Biochimica et biophysica acta.

Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis*

E. Deitch, Z. Spolarics, E. Villanueva, 2007, Critical care medicine.

Rapid detection of glucose‐6‐phosphate dehydrogenase type A‐202A/376G deficiency by allele‐specific polymerase chain reaction

Z. Spolarics, M. Siddiqi, Amy M. Liese, 2000, American journal of hematology.

A carbohydrate-rich diet stimulates glucose-6-phosphate dehydrogenase expression in rat hepatic sinusoidal endothelial cells.

Z. Spolarics, 1999, The Journal of nutrition.

(CDl lb/CDl8) Monoclonal Antibody Protects Against Ischemia-reperfusion Injury in Rat Liver

Jaeschke, Z. Spolarics, Bautista, 2005 .

Directional X Chromosome Skewing of White Blood Cells from Subjects with Heterozygous Mosaicism for the Variant IRAK1 Haplotype

D. Livingston, Z. Spolarics, A. Mosenthal, 2019, Inflammation.

Tumor Necrosis Factor Increases In Vivo Glucose Uptake in Hepatic Nonparenchymal Cells

Á. Schuler, J. Spitzer, C. Lang, 1991, Journal of leukocyte biology.

Monoclonal antibody against the CD18 adhesion molecule stimulates glucose uptake by the liver and hepatic nonparenchymal cells

J. Spitzer, Z. Spolarics, A. Bautista, 1993, Hepatology.

Intravenous injection of mesenteric lymph produced during hemorrhagic shock decreases RBC deformability in the rat.

E. Deitch, M. Senthil, M. Condon, 2011, The Journal of trauma.

Extracellular ATP protects against sepsis through macrophage P2X7 purinergic receptors by enhancing intracellular bacterial killing

M. Idzko, K. Erdélyi, Z. Nemeth, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

In vivo metabolic response of hepatic nonparenchymal cells and leukocytes to granulocyte‐macrophage colony‐stimulating factor

Á. Schuler, J. Spitzer, C. Lang, 1992, Journal of leukocyte biology.