T. Ide

发表

Increased secretion of very low density lipoprotein triglyceride following inhibition of long chain fatty acid oxidation in isolated rat liver.

J. Ontko, T. Ide, 1981, The Journal of biological chemistry.

Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance*

T. Kadowaki, T. Yamauchi, N. Kubota, 2006, Journal of Biological Chemistry.

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

P. Froguel, T. Kadowaki, A. Tsuchida, 2007, Nature Medicine.

A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.

Y. Yazaki, T. Kadowaki, Y. Akanuma, 1998, Diabetes.

Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha.

T. Kadowaki, M. Suzuki, T. Ide, 1999, Biochemical and biophysical research communications.

SREBPs suppress IRS-2-mediated insulin signalling in the liver

A. Fukamizu, H. Sone, H. Shimano, 2004, Nature Cell Biology.

A novel PPARalpha agonist ameliorates insulin resistance in dogs fed a high-fat diet.

M. Nagasawa, T. Ide, M. Tsunoda, 2008, American journal of physiology. Endocrinology and metabolism.

A novel PPAR (cid:1) agonist ameliorates insulin resistance in dogs fed a high-fat diet

M. Nagasawa, T. Ide, M. Tsunoda, 2008 .

Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis

M. Nagasawa, T. Ide, K. Murakami, 2012, Molecular and Cellular Endocrinology.

Chronic leptin treatment stimulates lipid oxidation in immortalized and primary mouse skeletal muscle cells.

T. Ide, M. Tsunoda, K. Murakami, 2009, Biochimica et biophysica acta.

Overexpression of MCP-1 in adipose tissues causes macrophage recruitment and insulin resistance

Ichiro, T. Kadowaki, T. Yamauchi, 2006 .

SREBP-1 Interacts with Hepatocyte Nuclear Factor-4α and Interferes with PGC-1 Recruitment to Suppress Hepatic Gluconeogenic Genes*

H. Sone, H. Shimano, N. Yahagi, 2004, Journal of Biological Chemistry.

Direct evidence for leptin-induced lipid oxidation independent of long-form leptin receptor.

T. Ide, M. Tsunoda, K. Murakami, 2010, Biochimica et biophysica acta.

Design, synthesis, and evaluation of substituted phenylpropanoic acid derivatives as human peroxisome proliferator activated receptor activators. Discovery of potent and human peroxisome proliferator activated receptor alpha subtype-selective activators.

Masahiro Suzuki, H. Miyachi, T. Ide, 2003, Journal of medicinal chemistry.

Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice.

T. Ide, M. Tsunoda, K. Murakami, 2004, Medical science monitor : international medical journal of experimental and clinical research.

The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation*

F. Tashiro, H. Koga, T. Kadowaki, 2009, Journal of Biological Chemistry.

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Y. Terauchi, N. Kubota, P. Froguel, 2001, Nature Medicine.

p53 Activation in Adipocytes of Obese Mice*

H. Shimano, N. Yahagi, N. Yamada, 2003, Journal of Biological Chemistry.

Absence of Sterol Regulatory Element-binding Protein-1 (SREBP-1) Ameliorates Fatty Livers but Not Obesity or Insulin Resistance inLep ob /Lep ob Mice*

H. Shimano, N. Yahagi, N. Yamada, 2002, The Journal of Biological Chemistry.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.

H. Sone, H. Shimano, N. Yahagi, 2003, Molecular endocrinology.

Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes

T. Ide, K. Murakami, Minoru Ito, 2010, Journal of Lipid Research.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Hitoshi Shimano, Takashi Matsuzaka, Hirohito Sone, 2003, Molecular endocrinology.

Cross-Talk between Peroxisome Proliferator-Activated Receptor ( PPAR ) and Liver X Receptor ( LXR ) in Nutritional Regulation of Fatty Acid Metabolism

H. Sone, H. Shimano, N. Yahagi, 2003 .

The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance*

Y. Terauchi, T. Kadowaki, T. Yamauchi, 2001, The Journal of Biological Chemistry.

Fatty-acyl-CoA thioesters inhibit recruitment of steroid receptor co-activator 1 to alpha and gamma isoforms of peroxisome-proliferator-activated receptors by competing with agonists.

T. Kadowaki, T. Ide, T Kadowaki, 2001, The Biochemical journal.

Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.

A. Itai, Y. Terauchi, T. Kadowaki, 2001, The Journal of clinical investigation.

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

H. Sone, H. Shimano, N. Yahagi, 2006, Nature Medicine.

Identification of a functional peroxisome proliferator-activated receptor (PPAR) response element (PPRE) in the human apolipoprotein A-IV gene.

T. Ide, K. Murakami, Yunike Akasaka, 2009, Biochemical pharmacology.

Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor α (PPARα) agonist in human hepatoma cells

T. Ide, K. Murakami, Yunike Akasaka, 2007 .

Sterol Regulatory Element-binding Proteins Activate Insulin Gene Promoter Directly and Indirectly through Synergy with BETA2/E47*

H. Sone, H. Shimano, N. Yahagi, 2005, Journal of Biological Chemistry.

Polyunsaturated Fatty Acids Suppress Sterol Regulatory Element-binding Protein 1c Promoter Activity by Inhibition of Liver X Receptor (LXR) Binding to LXR Response Elements*

H. Sone, H. Shimano, N. Yahagi, 2002, The Journal of Biological Chemistry.

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.

Y. Terauchi, T. Kadowaki, T. Yamauchi, 2001, The Journal of biological chemistry.

Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats.

T. Ide, K. Murakami, T. Mochizuki, 2000, Metabolism: clinical and experimental.

A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes

T. Ide, M. Tsunoda, K. Murakami, 2013, Journal of Lipid Research.

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.

T. Kodama, T. Kawai, Kenji Inoue, 2011, Cell metabolism.

Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes[S]

T. Ide, K. Murakami, Yunike Akasaka, 2011, Journal of Lipid Research.

ited when insulin decreased the CIDEA mRNA level. Small interfering RNA-mediated depletion of CIDEA inhibited starvation-induced apoptosis similarly to insulin and restored insulin deprivation-reduced adipocyte number, whereas CIDEC depletion did not. Lipid droplet size of adipocytes was increased w

T. Ide, K. Murakami, Minoru Ito, 2010 .

Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins

Yusuke Tsutsui, T. Ide, Yunike Akasaka, 2023, iScience.

Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells.

T. Ide, K. Murakami, Yunike Akasaka, 2007, Biochemical pharmacology.

Design, synthesis and evaluation of substituted phenylpropanoic acid derivatives as peroxisome proliferator-activated receptor (PPAR) activators: novel human PPARalpha-selective activators.

H. Miyachi, T. Ide, M. Tsunoda, 2002, Bioorganic & Medicinal Chemistry Letters.

Pharmacological characterization of a human-specific peroxisome proliferater-activated receptor alpha (PPARalpha) agonist in dogs.

T. Ide, M. Tsunoda, K. Murakami, 2004, Biochemical pharmacology.

Amelioration by KRP-297, a new thiazolidinedione, of impaired glucose uptake in skeletal muscle from obese insulin-resistant animals.

T. Ide, M. Tsunoda, K. Murakami, 1999, Metabolism: clinical and experimental.

Design, synthesis and evaluation of substituted phenylpropanoic acid derivatives as peroxisome proliferator-activated receptor (PPAR) activators: novel human PPARalpha-selective activators.

H. Miyachi, T. Ide, M. Tsunoda, 2002, Bioorganic & medicinal chemistry letters.