O. James

David C. Jones, S. Pearce, A. Floreani, 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Patterns of autoimmunity in primary biliary cirrhosis patients and their families: a population-based cohort study.

David C. Jones, D. Jones, O. James, 2004, QJM : monthly journal of the Association of Physicians.

Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance.

C. Day, O. James, 1998, Journal of hepatology.

A disease of emerging identity and importance

C. Day, O. James, 1998 .

Induction of remission in hepatocellular carcinoma with a new thymidylate synthase inhibitor, CB3717. A phase II study.

A. Harris, N. Curtin, M. Bassendine, 1987, Journal of hepatology.

Guidelines for selection of patients for liver transplantation in the era of donor-organ shortage

J. Neuberger, O. James, 1999, The Lancet.

Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver

M. Bennett, A. Burt, C. Day, 1995, The Lancet.

Ursodeoxycholic acid treatment for chronic cholestatic liver disease.

O. James, 1990, Journal of hepatology.

GALLSTONES PRESENTING AS MENTAL AND PHYSICAL DEBILITY IN THE ELDERLY

C. Venables, O. James, O. James, 1984, The Lancet.

Hepatic drug clearance: the effect of age using indocyanine green as a model compound.

H. Wynne, M. Rawlins, J. Goudevenos, 1990, British journal of clinical pharmacology.

The effect of age on pathways of drug metabolism in human liver.

M. Rawlins, O. James, F. Williams, 1984, Age and ageing.

Effects of age and gender on in vitro properties of human liver microsomal monooxygenases

H. Wynne, O. James, M. McManus, 1990, Clinical pharmacology and therapeutics.

Non-alcoholic steatohepatitis: another disease of affluence

C. Day, O. James, 1999, The Lancet.

Primary biliary cirrhosis: clinical and associated autoimmune features and natural history.

David C. Jones, D. Jones, M. Bassendine, 1998, Clinics in liver disease.

The acute and subchronic effects of ketoconazole on hepatic microsomal monooxygenases in the rat.

R. G. Thomson, M. Rawlins, O. James, 1988, Biochemical pharmacology.

Progression of autoimmune damage in primary biliary cirrhosis: an immunohistochemical study.

A. Floreani, M. Bennett, S. McLachlan, 1989, Autoimmunity.

The association of age and frailty with paracetamol conjugation in man.

H. Wynne, M. Rawlins, O. James, 1990, Age and ageing.

Paraproteins in primary biliary cirrhosis.

O. James, A. Bird, H. Mitchison, 1986, The Quarterly journal of medicine.

Heterozygotes for HFE mutations have no increased risk of advanced alcoholic liver disease

J. Grove, A. Burt, C. Day, 1998, Gut.

No evidence for involvement of type 1 collagen structural genes in 'genetic predisposition' to alcoholic cirrhosis.

B. Sykes, C. Day, D. Ogilvie, 1992, Journal of hepatology.

Reduced serum lipoprotein(a) levels in patients with primary biliary cirrhosis.

M. Farrer, F. Game, J. Idle, 1994, Atherosclerosis.

Metabolic bone disease in primary biliary cirrhosis at presentation.

M. Bassendine, O. James, A. Malcolm, 1988, Gastroenterology.

CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis.

S. Pearce, K. Agarwal, B. Vaidya, 2000, Journal of hepatology.

A study of nutritional deficits of long-stay geriatric patients.

P. Kelly, O. James, O. James, 1993, Age and ageing.

Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort

A. Chetwynd, W. Craig, O. James, 2004, Gut.

Cancer risk in primary biliary cirrhosis: a study in northern England

D. Howel, D. Jones, O. James, 1999, Gut.

The Geoepidemiology of Primary Biliary Cirrhosis

O. James, J. Metcalf, Jane Metcalf1, 1997, Seminars in liver disease.

Who are the frail elderly?

H. Wynne, M. Rawlins, O. James, 1988, The Quarterly journal of medicine.

Hepatitis C virus infection in the elderly.

M. Bassendine, O. James, J. Watson, 1996, QJM : monthly journal of the Association of Physicians.

The natural history of nonalcoholic fatty liver: A follow‐up study

M. Bennett, A. Burt, C. Day, 1995, Hepatology.

Quantitative analysis of macrophages and perisinusoidal cells in primary biliary cirrhosis

A. Burt, O. James, S. Johnson, 1994, Histopathology.

HLA-DR antigens in primary biliary cirrhosis: lack of association.

M. Bassendine, O. James, P. Dewar, 1985, Gut.

Familial primary biliary cirrhosis reassessed: a geographically-based population study.

David C. Jones, D. Jones, M. Bassendine, 1999, Journal of hepatology.

The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol dehydrogenase genotype.

J. Grove, C. Day, A. Daly, 1998, Pharmacogenetics.

A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis.

M. Hudson, D. Jones, C. Day, 2007, Journal of hepatology.

Molecular aspects of the M2 autoantigens in primary biliary cirrhosis: What a difference a year makes

S. Yeaman, M. Bassendine, O. James, 1989, Hepatology.

C ASE R EPORT: Oral antioxidant therapy for the treatment of primary biliary cirrhosis: A pilot study

David C. Jones, P. Cann, O. James, 1999, Journal of gastroenterology and hepatology.

Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis: results of a multicentre, randomized, placebo‐controlled, cross‐over trial

D. Jones, O. James, D. Burke, 2003, Alimentary pharmacology & therapeutics.

The Canadian multi-center double-blind randomized controlled trial of ursodeoxycholic acid in primary biliary cirrhosis: Heathcote EJ, Cauch-Duder K, Walker V, Bailey RJ, Blendis LM, Ghent CM, Michieletti P, et al. Hepatology 1994;19:1149–1156

David E. J. Jones, M. Bassendine, O. James, 1995 .

Post-transfusion hepatitis after cardiac surgery

O. James, J. Collins, 1984 .

Platelet associated immunoglobulins in primary biliary cirrhosis: a cause of thrombocytopenia?

M. Bassendine, O. James, J. Collins, 1985, Gut.

PRIMARY BILIARY CIRRHOSIS: IDENTIFICATION OF TWO MAJOR M2 MITOCHONDRIAL AUTOANTIGENS

S. Yeaman, M. Bassendine, O. James, 1988, The Lancet.

Tamoxifen: a novel treatment for primary biliary cirrhosis?

M. Bassendine, O. James, M. Prince, 2004, Liver international : official journal of the International Association for the Study of the Liver.

Reactivity of primary biliary cirrhosis sera with Escherichia coli dihydrolipoamide acetyltransferase (E2p): characterization of the main immunogenic region.

J. Guest, Sohail T. Ali, S. Yeaman, 1990, Proceedings of the National Academy of Sciences of the United States of America.

The epidemiology of primary biliary cirrhosis.

O. James, M. Prince, 2003, Clinics in liver disease.

Lentil-lectin-reactive alpha-fetoprotein in the differential diagnosis of benign and malignant liver disease.

O. James, P. Buamah, A. Skillen, 1986, Clinical chemistry.

Low prevalence of antibody to hepatitis C virus in North East England

M. Bassendine, O. James, B. Cohen, 1990, Journal of medical virology.

Ageing and duodenal morphometry.

P. Kelly, M. Bennett, O. James, 1992, Journal of clinical pathology.

An exploratory population‐based case‐control study of primary biliary cirrhosis

C. Fischbacher, R. Bhopal, D. Howel, 2000, Hepatology.

Human pyruvate dehydrogenase complex as an autoantigen in primary biliary cirrhosis.

S. Yeaman, M. Bassendine, O. James, 1993, Clinical science.

Osteoporosis in primary biliary cirrhosis revisited

J. Newton, D. Jones, M. Bassendine, 2001, Gut.

Clarification of the identity of the major M2 autoantigen in primary biliary cirrhosis.

C. Ragan, J. Lindsay, S. Yeaman, 1991, Clinical science.

Primary biliary cirrhosis. Quantitation of autoantibodies to purified mitochondrial enzymes and correlation with disease progression.

P. Kelly, S. Yeaman, M. Bassendine, 1990, Gastroenterology.

Sodium status and the renin‐angiotensin‐aldosterone system in compensated liver disease

A. Shore, R. Wilkinson, O. James, 1981, European journal of clinical investigation.

Portal hypertension secondary to arterio-portal fistulae: two unusual cases.

G. Aithal, O. James, J. Rose, 1999, Liver.

Digoxin-like factors in liver disease.

C. Day, O. James, 1989, Journal of hepatology.

Is measurement of type III procollagen amino propeptide useful in primary biliary cirrhosis?

P. Kelly, M. Bassendine, O. James, 1989, Journal of hepatology.

LOW PREVALENCE OF HEPATITIS B IN MENTAL HANDICAP HOSPITAL

R. G. Thomson, M. Rawlins, O. James, 1989, The Lancet.

Polymerase chain reaction for detection of the alpha-1-antitrypsin Z allele in chronic liver disease.

M. Bassendine, O. James, I. Mcintosh, 1990, Journal of hepatology.

Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis.

J. Guest, S. Yeaman, M. Bassendine, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Primary biliary cirrhosis: epidemiology helping the clinician

R. Bhopal, D. Howel, O. James, 1996, BMJ.

OCCUPATIONAL VITILIGO INDUCED BY p-tert-BUTYLPHENOL, A SYSTEMIC DISEASE?

C. J. Stevenson, O. James, R. Mayes, 1977, The Lancet.

Prospective study of post-transfusion hepatitis after cardiac surgery in a British centre.

R. Ferner, M. Bassendine, O. James, 1983, British medical journal.

The Diurnal Profile of Gastric Pepsin Activity Is Reduced with Helicobacter pylori Infection

J. Newton, O. James, A. Allen, 2004, Digestive Diseases and Sciences.

Steatohepatitis: a tale of two "hits"?

C. Day, O. James, 1998, Gastroenterology.

Serial serum AFP heterogeneity changes in patients with hepatocellular carcinoma during chemotherapy

A. Harris, O. James, P. Buamah, 2004, Cancer Chemotherapy and Pharmacology.

Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717.

A. Harris, N. Curtin, M. Bassendine, 1986, British Journal of Cancer.

The association of age with the activity of alcohol dehydrogenase in human liver.

H. Wynne, M. Rawlins, O. James, 1992, Age and ageing.

No specific association between primary biliary cirrhosis and bacteriuria?

R. Freeman, A. Floreani, M. Bassendine, 1989, Journal of hepatology.

The value of tumour marker kinetics in the management of patients with primary hepatocellular carcinoma

O. James, P. Buamah, A. Skillen, 1988, Journal of surgical oncology.

Parenchymal liver disease in the elderly

O. James, O. James, 1997, Gut.

Metastatic breast carcinoma presenting as acute liver failure and portal hypertension

M. Hudson, D. Jones, K. Agarwal, 2002, American Journal of Gastroenterology.

Liver disease in the elderly.

M. Mahon, O. James, 1994, Journal of clinical gastroenterology.

Development of autoimmune hepatitis following liver transplantation for primary biliary cirrhosis

David C. Jones, B. Portmann, M. Hudson, 1999, Hepatology.

The failing malignant liver

O. James, B. Smith, 1998, Gut.

Aspects of nutrition in the elderly.

O. James, D. Beaumont, 1985, Clinics in gastroenterology.

Bacterial contamination of the small intestine is an important cause of occult malabsorption in the elderly.

O. James, J. Dutton, A. McEvoy, 1983, British medical journal.

Laxative-induced Diarrhoea: A Continuing Clinical Problem

J. Cummings, G. Sladen, O. James, 1974, British medical journal.

HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility

P. Donaldson, K. Agarwal, D. Jones, 2001, Gut.

Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use.

D. Jones, O. James, M. Prince, 2000, Journal of hepatology.

The E1 alpha and beta subunits of the pyruvate dehydrogenase complex are M2'd' and M2'e' autoantigens in primary biliary cirrhosis.

S. Yeaman, M. Bassendine, O. James, 1989, Clinical science.

Identification and Characterization of Four M2 Mitochondrial Autoantigens in Primary Biliary Cirrhosis

S. Yeaman, M. Bassendine, O. James, 1989, Seminars in liver disease.

Effects of physical activity and age on mitochondrial function.

D. Turnbull, M. Johnson, O. James, 1996, QJM : monthly journal of the Association of Physicians.

Unsuspected giardiasis as a cause of malnutrition and diarrhoea in the elderly.

O. James, D. Beaumont, 1986, British medical journal.

INCIDENCE AND PROGNOSTIC IMPORTANCE OF JAUNDICE AFTER CARDIOPULMONARY BYPASS SURGERY

M. Bassendine, O. James, R. Ferner, 1983, The Lancet.

Dextropropoxyphene induced hepatotoxicity mimicking biliary tract disease.

M. Bennett, M. Bassendine, O. James, 1986, Gut.

The occurence and significance of microaggregates in stored blood

O. James, 2004, European journal of intensive care medicine.

Analysis of H LA-class-li-encoded antigen-processing genes TAP1 and TAP2 in primary biliary cirrhosis

J. Idle, A. Daly, M. Bassendine, 1994 .

Case–control studies of risk factors for primary biliary cirrhosis in two United Kingdom populations

O. James, M. Prince, S. Ducker, 2010, Gut.

populations biliary cirrhosis in two United Kingdom control studies of risk factors for primary - Case

O. James, M. Prince, S. Ducker, 2010 .

The geographical distribution of primary biliary cirrhosis in a well‐defined cohort

Peter Diggle, Amanda Chetwynd, P. Diggle, 2001, Hepatology.

Development, validation, and evaluation of the PBC-40, a disease specific health related quality of life measure for primary biliary cirrhosis

A. Jacoby, J. Newton, D. Buck, 2005, Gut.

The true impact of fatigue in primary biliary cirrhosis: a population study.

David E. J. Jones, M. Bassendine, O. James, 2002, Gastroenterology.

Primary biliary cirrhosis once rare, now common in the United Kingdom?

D. Howel, A. Burt, O. James, 1999, Hepatology.

Duodenal brush-border mucosal glucose transport and enzyme activities in aging man and effect of bacterial contamination of the small intestine

J. Mathers, B. Hirst, O. James, 1993, Digestive Diseases and Sciences.

Tumour necrosis factor-a promoter polymorphisms in primary biliary cirrhosis

J. Newton, David E. J. Jones, J. Grove, 1999 .

M2 AUTOANTIGENS IN PRIMARY BILIARY CIRRHOSIS

S. Yeaman, M. Bassendine, O. James, 1989, The Lancet.

Defining the immunogenetic susceptibility to primary biliary cirrhosis

R. Chapman, R. Campbell, K. Fleming, 1994, Hepatology.

Non-parenchymal cell responses in paracetamol (acetaminophen)-induced liver injury.

A. Burt, O. James, J. Mathew, 1994, Journal of hepatology.

The effect of alcoholic cirrhosis on the two kinetic components (high and low affinity) of the microsomal 0-deethylation of 7-ethoxycoumarin in human liver

M. Rawlins, O. James, F. Williams, 2004, European Journal of Clinical Pharmacology.

The Effect of Alcoholic Cirrhosis on the Two Kinetic Components (High and Low Affinity) of the Microsomal O-Deethylation of 7-Ethoxycoumarin in Human Liver

M. Rawlins, O. James, F. Williams, 1984 .

Hepatic steatosis: Innocent bystander or guilty party?

C. Day, O. James, 1998, Hepatology.

Vasculitis in primary biliary cirrhosis--response to prednisolone.

M. Bassendine, O. James, P. Crook, 1990, The Quarterly journal of medicine.

A trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis

M. Hudson, D. Jones, C. Day, 2002 .

Assessing quality of life in primary biliary cirrhosis.

A. Jacoby, D. Buck, David E. J. Jones, 2004, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

Tumour necrosis factor-alpha promoter polymorphisms in primary biliary cirrhosis.

J. Newton, J. Grove, D. Jones, 1999, Journal of hepatology.

Natural history of early primary biliary cirrhosis

David E. J. Jones, M. Bassendine, O. James, 1996, The Lancet.

A controlled trial of prednisolone treatment in primary biliary cirrhosis. Three-year results.

C. Record, M. Bassendine, O. James, 1992, Journal of hepatology.

Tumour necrosis factor-α promoter polymorphisms in primary biliary cirrhosis

J. Newton, David E. J. Jones, J. Grove, 1999 .

Hepatic drug metabolism and ageing.

O. James, K. Woodhouse, O. James, 1990, British medical bulletin.

The acute effects of ethanol on acetanilide disposition in normal subjects, and in patients with liver disease.

O. James, I. Cobden, J. McKay, 1982, British journal of clinical pharmacology.

Grip strength and subjective fatigue in patients with primary biliary cirrhosis.

D. Jones, O. James, J. Goldblatt, 2001, JAMA.

Symptom development and prognosis in primary biliary cirrhosis: a study in two centers.

P. Kelly, J. Neuberger, Roger Williams, 1990, Gastroenterology.

M4 and M9 autoantigens in primary biliary cirrhosis--a negative study.

S. Yeaman, M. Bassendine, O. James, 1993, Journal of hepatology.

No Rise in Incidence but Geographical Heterogeneity in the Occurrence of Primary Biliary Cirrhosis in North East England

P. Norman, R. McNally, P. James, 2014, American journal of epidemiology.

Pain as a complication of use of opiate antagonists for symptom control in cholestasis.

M. Hudson, C. Day, O. James, 2003, Gastroenterology.

The epidemiology of primary biliary cirrhosis in north-east England: an increasingly common disease?

O. James, M. Myszor, O.F.W. James, 1990, The Quarterly journal of medicine.

Positive Antimitochondrial Antibody, Normal Liver Function Tests: Is this Primary Biliary Cirrhosis?

M. Bennett, M. Bassendine, O. James, 1985 .

Presentation and mortality of primary biliary cirrhosis in older patients.

J. Newton, A. Burt, D. Jones, 2000, Age and ageing.

D-penicillamine for primary biliary cirrhosis.

O. James, 1985, Gut.

Flumecinol improves pruritus in cholestatic liver disease — A double blind placebo controlled trial

M. Rawlins, O. James, I. Turner, 1990 .

Is primary biliary cirrhosis a different disease in the elderly?

M. Bassendine, O. James, A. Lehmann, 1985, Gerontology.

Ranitidine increases the bioavailability of postprandial ethanol by the reduction of first pass metabolism.

P. Kelly, M. Bennett, C. Day, 1995, Gut.

Liver in metabolic diseases

O. James, 1984 .

Does primary biliary cirrhosis cluster in time?

C. Muirhead, R. McNally, O. James, 2015, Spatial and spatio-temporal epidemiology.

Are transient environmental agents involved in the cause of primary biliary cirrhosis? Evidence from space–time clustering analysis

R. McNally, O. James, Samantha Ducker, 2009, Hepatology.

Pure alcoholic fatty liver and progression to cirrhosis or fibrosis

A. Ho, A. Burt, C. Day, 1995, The Lancet.

Mitochondrial involvement in the ageing process. Facts and controversies

Margaret A. Johnson, D. Turnbull, O. James, 1997, Molecular and Cellular Biochemistry.

The Adherent Gastric Antral and Duodenal Mucus Gel Layer Thins with Advancing Age in Subjects Infected with Helicobacter pylori

J. Newton, J. Pearson, O. James, 2000, Gerontology.

Helicobacter pylori in vivo causes structural changes in the adherent gastric mucus layer but barrier thickness is not compromised

J. Newton, J. Pearson, O. James, 1998, Gut.

T‐cell responses to the components of pyruvate dehydrogenase complex in primary biliary cirrhosis

D. Jones, S. Yeaman, M. Bassendine, 1995, Hepatology.

Clinical features and prognosis of alcoholic liver disease in respect of advancing age.

J. Potter, O. James, 1987, Gerontology.

Autoimmune hepatitis in older patients.

J. Newton, O. James, A. Burt, 1997, Age and ageing.

Sequential coronary artery bypass grafting and orthotopic liver transplantation: a case report.

M. Hudson, M. Thick, O. James, 1996, Clinical transplantation.

The effect of alcoholic cirrhosis on the activities of microsomal aldrin epoxidase, 7-ethoxycoumarin O-de-ethylase and epoxide hydrolase, and on the concentrations of reduced glutathione in human liver.

M. Rawlins, O. James, F. Williams, 1983, British journal of clinical pharmacology.

2,5-Diphenyloxazole as a probe for microsomal mono-oxygenation in human and rat liver.

M. Rawlins, O. James, F. Williams, 1985, Xenobiotica; the fate of foreign compounds in biological systems.

The metabolism of 7-ethoxycoumarin in human liver microsomes and the effect of primary biliary cirrhosis: implications for studies of drug metabolism in liver disease.

M. Rawlins, O. James, K. Woodhouse, 1985, British Journal of Clinical Pharmacology.

7-Ethoxyresorufin deethylase (EROD) in human liver —The effect of alcoholic liver disease

M. Rawlins, O. James, F. Williams, 2006, European Journal of Clinical Pharmacology.

Blood ammonia and Helicobacter pylori.

P. Kelly, J. Mathers, O. James, 1992, Australian and New Zealand journal of medicine.

A biphasic illness associated with acute hepatitis A virus infection.

O. James, I. Cobden, 1986, Journal of hepatology.

Reduction in incidence of severe paracetamol poisoning

M. Hudson, O. James, M. Prince, 2000, The Lancet.

Natural history and demography of primary biliary cirrhosis

O. James, 1998 .

Hepatocellular carcinoma in north-east England: importance of hepatitis B infection and ex-tropical military service.

M. Bassendine, O. James, I. Cobden, 1986, The Quarterly journal of medicine.

Insulin action in cirrhosis

R. Heine, K. Alberti, R. Taylor, 1985, Hepatology.

Liver function and structure in survivors of acetaminophen poisoning

O. James, A. Hamlyn, A. Watson, 1977, The American Journal of Digestive Diseases.

Defining the immunogenetic susceptibility to primary biliary cirrhosis

R. Chapman, R. Campbell, K. Fleming, 1994, Hepatology.

Gastrointestinal and liver function of old age.

O. James, 1983, Clinics in gastroenterology.

Epidemiology and genetics of primary biliary cirrhosis.

O. James, M. Myszor, 1990, Progress in liver diseases.

Transjugular intrahepatic portosystemic shunt: a limited role in refractory ascites

M. Hudson, C. Record, M. Bassendine, 1997, European journal of gastroenterology & hepatology.

Age and the metabolism of drugs.

H. Wynne, M. Rawlins, O. James, 1987, The Quarterly journal of medicine.

The effect of age and frailty upon acetanilide clearance in man.

H. Wynne, M. Rawlins, O. James, 1989, Age and ageing.

Comparison of omeprazole and histamine H2-receptor antagonists in the treatment of elderly and young patients with reflux oesophagitis.

O. James, O. James, K. Parry-Billings, 1994, Age and ageing.