A. Olma

发表

Introduction of alpha-hydroxymethyamino acid residues in substrate specificity P1 position of trypsin inhibitor SFTI-1 from sunflower seeds retains its activity.

A. Jaśkiewicz, Ewa Zabłotna, A. Kret, 2006, Biochemical and biophysical research communications.

Carboxy terminus of vasopressin required for activity but not binding

M. Manning, A. Misicka, A. Olma, 1984, Nature.

Synthesis and absolute configuration of (+) α-hydroxymethyltyrosine by X-ray analysis of its N-benzoyl derivative

A. Olma, M. Leplawy, W. Wieczorek, 1991 .

α-Hydroxymethylaspartic acid: Synthesis and absolute configuration by X-ray analysis of its derivative (+)-4-benzoylamino-4-carboxy-γ-butyrolactone

A. Olma, M. Leplawy, W. Wieczorek, 1991 .

(−)-S-Benzyl-α-hydroxymethylcysteine: Confirmation of its (S)-configuration by x-ray analysis of itsN-benzoyl derivative

A. Olma, M. Leplawy, W. Wieczorek, 1989 .

Correction of vasopressin deficit in the lateral septum ameliorates social deficits of mouse autism model.

G. Guillon, M. Manning, F. Muscatelli, 2020, The Journal of clinical investigation.

Chemistry of α‐hydroxymethylserine: problems and solutions

A. Olma, M. Leplawy, U. Słomczyńska, 2008, Journal of peptide science : an official publication of the European Peptide Society.

TAPP analogs containing β3‐homo‐amino acids: synthesis and receptor binding

A. Lipkowski, P. Kosson, A. Olma, 2012, Journal of peptide science : an official publication of the European Peptide Society.

Control of Social Withdrawal of Mice Deficient for the Autism Gene Magel2 by Restoration of Vasopressin-Oxytocin Dialogue in Septum

G. Guillon, M. Manning, F. Muscatelli, 2019, bioRxiv.

The biological consequences of replacing hydrophobic amino acids in deltorphin I with amphiphilic alpha-hydroxymethylamino acids.

A. Lipkowski, A. Olma, M. Łachwa, 2003, The journal of peptide research : official journal of the American Peptide Society.

Synthesis, binding affinities and metabolic stability of dimeric dermorphin analogs modified with β3‐homo‐amino acids

A. Misicka, P. Kosson, A. Olma, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Solid-phase synthesis of 16 potent (selective and nonselective) in vivo antagonists of oxytocin.

M. Manning, A. Olma, W. Sawyer, 1989, Journal of medicinal chemistry.

Potent and selective antagonists of the antidiuretic responses to arginine-vasopressin based on modifications of [1-(beta-mercapto-beta,beta-pentamethylenepropionic acid),2-D-isoleucine,4- valine]arginine-vasopressin at position 4.

M. Manning, A. Misicka, A. Olma, 1984, Journal of medicinal chemistry.

Design of more potent antagonists of the antidiuretic responses to arginine-vasopressin.

M. Manning, A. Olma, W. Sawyer, 1982, Journal of medicinal chemistry.

Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics

G. Guillon, S. Stoev, M. Manning, 2012, Journal of neuroendocrinology.

An efficient synthesis of optically pure α-alkyl-β-azido- and α-alkyl-β-aminoalanines via ring opening of 3-amino-3-alkyl-2-oxetanones

A. Olma, A. Kudaj, 2007 .

An Efficient Synthesis of Optically Active 3‐Amino‐3‐alkyl‐2‐oxetanones.

A. Olma, A. Kudaj, 2005 .

ALPHA -HYDROXYMETHYLPHENYLGLYCINE AND ALPHA -HYDROXYMETHYLPHENYLALANINE : SYNTHESIS, RESOLUTION, AND ABSOLUTE CONFIGURATION

A. Olma, 1996 .

Biphalin analogs containing β3-homo-amino acids at the 4,4′ positions: Synthesis and opioid activity profiles

A. Lipkowski, P. Kosson, A. Olma, 2015, Peptides.

A convenient route to optically pure α-alkyl-β-(sec-amino)alanines

A. Olma, A. Lasota, A. Kudaj, 2011, Amino Acids.

C-terminal deletions in agonistic and antagonistic analogues of vasopressin that improve their specificities for antidiuretic (V2) and vasopressor (V1) receptors.

M. Manning, A. Misicka, A. Olma, 1987, Journal of medicinal chemistry.

No requirement of cyclic conformation of antagonists in binding to vasopressin receptors

M. Manning, W. H. Sawyer, A. Olma, 1987, Nature.

Potent antagonists of the antidiuretic responses to arginine-vasopressin based on modifications of [1-(beta-mercapto-beta,beta-cyclopentamethylenepropionic acid),2-D- phenylalanine,4-valine]arginine-vasopressin at position 4.

M. Manning, A. Olma, W. Sawyer, 1983, Journal of medicinal chemistry.

The Biological Consequences of Replacing d‐Ala in Biphalin with Amphiphilic α‐Alkylserines

A. Lipkowski, A. Olma, A. Lasota, 2014, Chemical biology & drug design.

POTENT AND SELECTIVE ANTAGONISTS OF THE ANTIDIURETIC RESPONSES TO ARGININE-VASOPRESSIN BASED ON MODIFICATIONS OF (1-(β-MERCAPTO-β,β-PENTAMETHYLENEPROPIONIC ACID), 2-D-ISOLEUCINE, 4-VALINE)ARGININE-VASOPRESSIN AT POSITION 4

M. Manning, A. Misicka, A. Olma, 1984 .

Potent Antagonists of the Antidiuretic Responses to Arginine-Vasopressin Based on Modifications of [1(β-Mercapto-β,β-cyclopentamethylenepropionic Acid)2-D-phenylalanine,4-valine]arginine-vasopressin at Position 4.

M. Manning, A. Olma, W. Sawyer, 1984 .

An investigation of position 3 in arginine vasopressin with aliphatic, aromatic, conformationally‐restricted, polar and charged amino acids

S. Stoev, M. Manning, A. Olma, 1999, Journal of peptide science : an official publication of the European Peptide Society.

Novel linear antagonists of the antidiuretic (V2) and vasopressor (V1) responses to vasopressin.

M. Manning, A. Olma, W. Sawyer, 2009, International journal of peptide and protein research.

An investigation of position 3 in arginine vasopressin (AVP)

S. Stoev, M. Manning, A. Olma, 2002 .

Position Three in Vasopressin Antagonist Tolerates Conformationally Restricted and Aromatic Amino Acid Substitutions: A Striking Contrast with Vasopressin Agonists

S. Stoev, M. Manning, A. Olma, 1997, Journal of peptide science : an official publication of the European Peptide Society.

Neuroanatomical distribution and function of the vasopressin V1B receptor in the rat brain deciphered using specific fluorescent ligands.

G. Guillon, M. Manning, Y. Ueta, 2017, General and comparative endocrinology.

The impact of β‐azido(or 1‐piperidinyl)methylamino acids in position 2 or 3 on biological activity and conformation of dermorphin analogues

M. Maciejczyk, A. Misicka, P. Kosson, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Synthesis, Biological Activity, and NMR‐Based Structural Studies of Deltorphin I Analogs Modified in Message Domain with a New α,α‐Disubstituted Glycines

M. Maciejczyk, A. Olma, A. Ejchart, 2016, Chemical biology & drug design.

Analogues of deltorphin I containing conformationally restricted amino acids in position 2: structure and opioid activity

A. Lipkowski, A. Olma, A. Ejchart, 2015, Journal of peptide science : an official publication of the European Peptide Society.

Synthesis and receptor binding of opioid peptide analogues containing β3‐homo‐amino acids

P. Kosson, A. Olma, A. Ejchart, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Analogs of arginine vasopressin modified in position 3 with (R)-alpha-hydroxymethylphenylalanine.

A. Olma, J. Slaninová, B. Lammek, 1999, The journal of peptide research : official journal of the American Peptide Society.

An investigation of position 3 in arginine vasopressin with aliphatic, aromatic, conformationally-restricted, polar and charged amino acidsSymbols and abbreviations are in accordance with the recommendations of the IUPAC-IUB Commission on Biochemical Nomenclature (Eur. J. Biochem. 180, A9-A11, 1989)

S. Stoev, M. Manning, A. Olma, 1999 .

Design of potent and selective linear antagonists of vasopressor (V1-receptor) responses to vasopressin.

S. Stoev, M. Manning, A. Misicka, 1990, Journal of medicinal chemistry.

Synthesis and binding properties of endomorphin-2 analogs containing α-hydroxymethyl amino acids

D. Tourwé, A. Olma, 2000, Letters in Peptide Science.

Design of more potent and selective antagonists of the antidiuretic responses to arginine-vasopressin devoid of antidiuretic agonism.

M. Manning, A. Olma, W. Sawyer, 1982, Journal of medicinal chemistry.

DESIGN OF MORE POTENT AND SELECTIVE ANTAGONISTS OF THE ANTIDIURETIC RESPONSES TO ARGININE-VASOPRESSIN DEVOID OF ANTIDIURETIC AGONISM

M. Manning, A. Olma, W. Sawyer, 1982 .

Effects of a D-Cys6/L-Cys6 interchange in nonselective and selective vasopressin and oxytocin antagonists.

M. Manning, A. Olma, W. Sawyer, 1995, Journal of medicinal chemistry.

A convenient route to optically pure α-alkyl-β-(sec-amino)alanines

A. Olma, bullet A Lasota, bullet A Kudaj, 2011, Amino Acids.

A convenient transformation of a-alkylserines into a-halogenomethyl-a-alkylglycines

A. Olma, A. Kudaj, 2008 .

Synthesis and receptor binding of opioid peptide analogues containing β3‐homo‐amino acids

P. Kosson, A. Olma, A. Ejchart, 2009, Journal of peptide science : an official publication of the European Peptide Society.

α-Hydroxymethylphenylglycine and α- Hydroxymethylphenylalanine: Synthesis, Resolution, and Absolute Configuration.

A. Olma, 1997 .