J. Hauptmann

发表

Synthetic inhibitors of thrombin and factor Xa: from bench to bedside.

J. Stürzebecher, J. Hauptmann, J. Stürzebecher, 1999, Thrombosis research.

Synthetic inhibitors of bovine factor Xa and thrombin comparison of their anticoagulant efficiency.

J. Stürzebecher, F. Markwardt, U. Stürzebecher, 1989, Thrombosis research.

Synthetic thrombin inhibitors as anticoagulants pharmacological aspects.

F. Markwardt, J. Hauptmann, 1993, Advances in experimental medicine and biology.

Pharmacology of Synthetic Thrombin Inhibitors of the Tripeptide Type

J. Hauptmann, B. Kaiser, 1992 .

Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalanines.

W. Bode, M. Renatus, J. Stürzebecher, 1999, European journal of biochemistry.

Pharmacological characterization of a new highly effective synthetic thrombin inhibitor.

F. Markwardt, J. Hauptmann, B. Kaiser, 1985, Biomedica biochimica acta.

Influence of Structural Variations in Peptidomimetic 4-Amidinophenylalanine-Derived Thrombin Inhibitors on Plasma Clearance and Biliary Excretion in Rats

J. Stürzebecher, T. Steinmetzer, J. Hauptmann, 2002, Pharmaceutical Research.

Influence of Indocyanine Green on Plasma Disappearance and Biliary Excretion of a Synthetic Thrombin Inhibitor of the 3-Amidinophenyl-alanine Piperazide-type in Rats

J. Stürzebecher, J. Hauptmann, J. Stürzebecher, 1998, Pharmaceutical Research.

Pharmacokinetics of an emerging new class of anticoagulant/antithrombotic drugs

J. Hauptmann, 2001, European Journal of Clinical Pharmacology.

Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine.

J. Stürzebecher, J. Hauptmann, H. Vieweg, 1997, Journal of medicinal chemistry.

Transport of Peptidomimetic Thrombin Inhibitors with a 3-Amidino-Phenylalanine Structure: Permeability and Efflux Mechanism in Monolayers of a Human Intestinal Cell Line (Caco-2)

G. Klebe, H. Gohlke, J. Stürzebecher, 2001, Pharmaceutical Research.

Reduction of a benzamidoxime derivative to the corresponding benzamidine in vivo and in vitro.

J. Hauptmann, B. Kaiser, M. Paintz, 1988, Die Pharmazie.

Pharmacological Studies on the Antithrombotic Action of Hirudin in Experimental Animals

F. Markwardt, C. Klessen, J. Hauptmann, 1982, Thrombosis and Haemostasis.

Laboratory Studies of the Atmospheric Decay of Hydrocarbons in the NOx Free Atmosphere

K. Bächmann, J. Hauptmann, B. Kusserow, 1997 .

Factor Xa Inhibitors as Novel Antithrombotic Agents: Facts and Perspectives

J. Hauptmann, B. Kaiser, 1994 .

Anticoagulant and antithrombotic action of the factor Xa inhibitor antistasin (ATS).

J. Hauptmann, B. Kaiser, 1993, Thrombosis research.

Structure-Activity Relationships of New NAPAP-Analogs

T. Steinmetzer, J. Hauptmann, S. Künzel, 2001, Journal of enzyme inhibition and medicinal chemistry.

Advances in the development of thrombin inhibitors

T. Steinmetzer, J. Hauptmann, J. Stürzebecher, 2001, Expert opinion on investigational drugs.

Synthetic inhibitors of serine proteinases. XVI. Influence of 3- and 4-amidinobenzyl derivatives on the formation and action of thrombin.

F. Markwardt, J. Hauptmann, P. Walsmann, 1978, Thrombosis Research.

Design of benzamidine-type inhibitors of factor Xa.

W. Bode, M. Stubbs, L. Moroder, 1998, Journal of medicinal chemistry.

Influence of hirudin on the consumption of antithrombin III in experimental DIC.

J. Hauptmann, E. Brüggener, 1988, Folia haematologica.

Studies on the anticoagulant and antithrombotic action of an irreversible thrombin inhibitor.

F. Markwardt, J. Hauptmann, 1980, Thrombosis research.

Pharmacologic Aspects of the Development of Selective Synthetic Thrombin Inhibitors as Anticoagulants

F. Markwardt, J. Hauptmann, F Markwardt, 1992, Seminars in thrombosis and hemostasis.

On the fibrinolytic action of BIS-6,7-Dimethoxyisoquinoline derivatives

F. Markwardt, J. Hauptmann, H. Klöcking, 1973 .

Comparison of the Anticoagulant and Antithrombotic Effects of Synthetic Thrombin and Factor Xa Inhibitors

F. Markwardt, J. Hauptmann, B. Kaiser, 1990, Thrombosis and Haemostasis.

Anticoagulant and Antithrombotic Action of Novel Specific Inhibitors of Thrombin

F. Markwardt, J. Hauptmann, B. Kaiser, 1980, Thrombosis and Haemostasis.

Differential effects of staphylokinase, streptokinase and tissue-type plasminogen activator on the lysis of retracted human plasma clots and fibrinolytic plasma parameters in vitro.

J. Hauptmann, E. Glusa, 1995, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Effect of heparin, hirudin, and a synthetic thrombin inhibitor on antithrombin III in thrombin-induced disseminated intravascular coagulation in rats.

F. Markwardt, J. Hauptmann, E. Brüggener, 1987, Haemostasis.

Determination of Organic Peroxides

K. Bächmann, J. Hauptmann, 1990 .

Anticoagulant action of synthetic tight binding inhibitors of thrombin in vitro and in vivo.

F. Markwardt, J. Hauptmann, B. Kaiser, 1985, Thrombosis research.

Studies on cardioactive steroids. II. Structure-activity relationships in the isolated guinea-pig heart.

J. Hauptmann, K. Haustein, 1974, Pharmacology.

Inhibition of the haemolytic complement activity by derivatives of benzamidine.

F. Markwardt, J. Hauptmann, 1977, Biochemical pharmacology.

New Bivalent Thrombin Inhibitors with N? (Methyl)Arginine at the P1-Position

S. Reissmann, A. Vogel, T. Steinmetzer, 2000 .

Pharmacological characterization of a new structural variant of 4-amidinophenylalanine amide-type synthetic thrombin inhibitor.

F. Markwardt, J. Hauptmann, B. Kaiser, 1989, Die Pharmazie.

Anticoagulant potential of synthetic and recombinant inhibitors of factor Xa and thrombin in vitro

J. Hauptmann, B. Kaiser, 1993, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.