P. Patston

发表

Substrate properties of C1 inhibitor Ma (alanine 434----glutamic acid). Genetic and structural evidence suggesting that the P12-region contains critical determinants of serine protease inhibitor/substrate status.

W. R. Wikoff, K. Skriver, A. Kaplan, 1991, The Journal of biological chemistry.

The role of conformational change in serpin structure and function

P. Gettins, P. Patston, M. Schapira, 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.

C1 Inhibitor Cross-linking by Tissue Transglutaminase*

P. Patston, M. Schapira, J. Hauert, 2000, The Journal of Biological Chemistry.

A Database of Recombinant Wild-type and Mutant Serpins

P. Gettins, P. Patston, P. Patston, 1994, Thrombosis and Haemostasis.

Serpin-ligand interactions.

S. Olson, P. Patston, F. Church, 2004, Methods.

Apparent Formation of Sodium Dodecyl Sulfate-stable Complexes between Serpins and 3,4-Dichloroisocoumarin-inactivated Proteinases Is Due to Regeneration of Active Proteinase from the Inactivated Enzyme*

S. Olson, P. Patston, I. Björk, 1997, The Journal of Biological Chemistry.

Linkage between the hormone binding site and the reactive center loop of thyroxine binding globulin.

P. Gettins, P. Patston, S. Suda, 2000, Archives of biochemistry and biophysics.

Formation and properties of C1‐inhibitor polymers

P. Patston, M. Schapira, J. Hauert, 1995, FEBS letters.

Reactivation of C1-inhibitor polymers by denaturation and gel-filtration chromatography.

P. Patston, M. Gauthier, 1997, Analytical biochemistry.

Structure and mechanism of action of serpins.

P. Gettins, P. Patston, M. Schapira, 1992, Hematology/oncology clinics of North America.

Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases.

P. Patston, Ahmed Ramaha, 2002, Archives of biochemistry and biophysics.

Low-affinity heparin stimulates the inactivation of plasminogen activator inhibitor-1 by thrombin

P. Patston, M. Schapira, 1994 .

Low-affinity heparin stimulates the inactivation of plasminogen activator inhibitor-1 by thrombin.

P. Patston, M. Schapira, 1994, Blood.

The inhibition of TNK-t-PA by C1-inhibitor

P. Patston, T. Sulikowski, 2001, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The Mechanism by Which Serpins Inhibit Thrombin and Other Serine Proteinases a

P. Gettins, P. Patston, M. Schapira, 1994, Annals of the New York Academy of Sciences.

Purification and properties of a protein activator of phosphorylated branched-chain 2-oxo acid dehydrogenase complex.

P. J. Randle, P. Patston, K. S. Lau, 1985, The Biochemical journal.

Effects of diet and of alloxan-diabetes on the activity of branched-chain 2-oxo acid dehydrogenase complex and of activator protein in rat tissues.

P. J. Randle, P. Patston, J. Espinal, 1984, The Biochemical journal.

Expression of matrix metalloproteinase genes in the rat intramembranous bone during postnatal growth and upon mechanical stresses.

J. Mao, P. Patston, J. Collins, 2005, Journal of biomechanics.

[22] Assay of total complex and activity state of branched-chain α-keto acid dehydrogenase complex and of activator protein in mitochondria, cells, and tissues

M. Beggs, P. J. Randle, P. Patston, 1988 .

Dephosphorylation and reactivation of phosphorylated purified ox‐kidney branched‐chain dehydrogenase complex by co‐purified phosphatase

P. J. Randle, P. Patston, H. Fatania, 1983, FEBS letters.

Regulation of C1-inhibitor function by binding to type IV collagen and heparin.

P. Patston, M. Schapira, 1997, Biochemical and biophysical research communications.

Studies on inhibition of neutrophil cathepsin G byα1-antichymotrypsin

P. Patston, 1995, Inflammation.

Inhibition of plasma kallikrein by C1-inhibitor: role of endothelial cells and the amino-terminal domain of C1-inhibitor

R. Welch, T. Grys, P. Patston, 2004, Thrombosis and Haemostasis.

The effect of cleavage by a Crotalus atrox alpha-proteinase fraction on the properties of C1-inhibitor.

J. Schifferli, P. Patston, M. Schapira, 1995, Toxicon : official journal of the International Society on Toxinology.

Serpins and other serine protease inhibitors.

P. Patston, 2000, Immunology today.

The effect of sex and age on antithrombin biosynthesis in the rat.

P. Patston, M. Schapira, Y. Kourteva, 1995, Thrombosis research.

α1‐Proteinase inhibitor mutants with specificity for plasma kallikrein and C1s but not C1

P. Patston, T. Sulikowski, Bryan A. Bauer, 2002, Protein science : a publication of the Protein Society.

Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen

P. Patston, M. Schapira, S. Ravindran, 2012, International journal of biomaterials.

Modulation of C 1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen

P. Patston, M. Schapira, S. Ravindran, 2012 .

Mechanism of serpin action: evidence that C1 inhibitor functions as a suicide substrate.

J. Beechem, P. Gettins, P. Patston, 1991, Biochemistry.

The reaction between plasmin and C1-inhibitor results in plasmin inhibition by the serpin mechanism

P. Patston, S. Ravindran, E. W. Brown, 2002, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The P6-P2 region of serpins is critical for proteinase inhibition and complex stability.

J. Huntington, P. Gettins, P. Patston, 1997, Biochemistry.

Reactivity of alpha 1-antitrypsin mutants against proteolytic enzymes of the kallikrein-kinin, complement, and fibrinolytic systems.

N. Roodi, R. Bischoff, J. Schifferli, 1990, The Journal of biological chemistry.

A common neoepitope is created when the reactive center of C1-inhibitor is cleaved by plasma kallikrein, activated factor XII fragment, C1 esterase, or neutrophil elastase.

P. Patston, M. Schapira, V. Marottoli, 1988, The Journal of clinical investigation.

C1 Inhibitor: Structure, function, biologic activity and angioedema

P. Patston, A. Davis, 2007 .

Serpins Are Suicide Substrates: Implications for the Regulation of Proteolytic Pathways

P. Gettins, P. Patston, M. Schapira, 1994, Seminars in thrombosis and hemostasis.

Rat tissue concentrations of branched-chain 2-oxo acid dehydrogenase complex. Re-evaluation by immunoassay and bioassay.

P. J. Randle, P. Patston, J. Espinal, 1986, The Biochemical journal.

S‐ovalbumin, an ovalbumin conformer with properties analogous to those of loop‐inserted serpins

J. Huntington, P. Gettins, P. Patston, 1995, Protein science : a publication of the Protein Society.

Serine protease inhibitors (serpins).

P. Patston, M. Schapira, 1991, Trends in cardiovascular medicine.

4 Branched-Chain Ketoacid Dehydrogenase

P. J. Randle, P. Patston, J. Espinal, 1987 .

Complement C1 inhibitor is produced by brain tissue and is cleaved in Alzheimer disease

D. Walker, P. Mcgeer, E. Mcgeer, 1995, Brain Research.

Influence of the P5 Residue on α1-Proteinase Inhibitor Mechanism*

P. Patston, C. Chaillan-Huntington, 1998, The Journal of Biological Chemistry.

Significance of secondary structure predictions on the reactive center loop region of seprins: a model for the folding of serpins into a metastable state

P. Gettins, P. Patston, P. Patston, 1996, FEBS letters.

Characterization of different high molecular weight angiotensinogen forms.

P. Patston, J. Célérier, Ahmed Ramaha, 2003, American journal of hypertension.

Serine protease inhibitors (serpins).

P. Patston, Marc Schapira, 1991, Trends in cardiovascular medicine.

Curriculum restructuring at a North American dental school: rationale for change.

K. Knoernschild, G. Adami, A. Obrez, 2007, Journal of dental education.