I. Verhamme

发表

A Fluorescent Probe Study of Plasminogen Activator Inhibitor-1

D. Lawrence, D. Ginsburg, J. Shore, 1995, The Journal of Biological Chemistry.

Serpin-Protease Complexes Are Trapped as Stable Acyl-Enzyme Intermediates (*)

D. Lawrence, D. Ginsburg, J. Shore, 1995, The Journal of Biological Chemistry.

Metals affect the structure and activity of human plasminogen activator inhibitor‐1. I. Modulation of stability and protease inhibition

D. Day, I. Verhamme, Lawrence C. Thompson, 2011, Protein science : a publication of the Protein Society.

Sucrose Octasulfate Selectively Accelerates Thrombin Inactivation by Heparin Cofactor II*

I. Verhamme, D. Kravtsov, D. Gailani, 2010, The Journal of Biological Chemistry.

The Preferred Pathway of Glycosaminoglycan-accelerated Inactivation of Thrombin by Heparin Cofactor II*

P. E. Bock, I. Verhamme, C. Jackson, 2004, Journal of Biological Chemistry.

Exosites in the substrate specificity of blood coagulation reactions

P. Panizzi, P. E. Bock, I. Verhamme, 2007, Journal of thrombosis and haemostasis : JTH.

Role of the Streptokinase α-Domain in the Interactions of Streptokinase with Plasminogen and Plasmin*

P. E. Bock, I. Verhamme, Ronald R. Bean, 2005, Journal of Biological Chemistry.

Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation.

J. Emsley, I. Verhamme, D. Gailani, 2017, Blood.

Factor XI anion‐binding sites are required for productive interactions with polyphosphate

I. Verhamme, J. Sheehan, J. Morrissey, 2013, Journal of thrombosis and haemostasis : JTH.

The dimeric structure of factor XI and zymogen activation.

Stephanie A. Smith, I. Verhamme, J. Morrissey, 2013, Blood.

Characterization of Novel Forms of Coagulation Factor XIa

P. E. Bock, I. Verhamme, D. Gailani, 2008, Journal of Biological Chemistry.

Proteases: Pivot Points in Functional Proteomics.

I. Verhamme, Sarah-Ellen Leonard, Ray C Perkins, 2018, Methods in molecular biology.

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

R. Huber, W. Bode, S. Kawabata, 2003, Nature.

Binding of Exosite Ligands to Human Thrombin

S. Olson, P. E. Bock, I. Verhamme, 2002, The Journal of Biological Chemistry.

The Use of Fluorescent Probes to Characterize Conformational Changes in the Interaction between Vitronectin and Plasminogen Activator Inhibitor-1*

J. Shore, D. Day, I. Verhamme, 1997, The Journal of Biological Chemistry.

The hyperglycemic byproduct methylglyoxal impairs anticoagulant activity through covalent adduction of antithrombin III.

H. Hamm, I. Verhamme, J. Schoenecker, 2014, Thrombosis research.

Pathogen activators of plasminogen

P. Panizzi, P. E. Bock, I. Verhamme, 2015, Journal of thrombosis and haemostasis : JTH.

Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis

G. Wojtkiewicz, Y. Iwamoto, C. Calcagno, 2020, Science Translational Medicine.

An update on factor XI structure and function.

Chan Li, J. Emsley, I. Verhamme, 2018, Thrombosis research.

Activation of factor XI by products of prothrombin activation.

I. Verhamme, J. Sheehan, D. Gailani, 2011, Blood.

Streptokinase Triggers Conformational Activation of Plasminogen through Specific Interactions of the Amino-terminal Sequence and Stabilizes the Active Zymogen Conformation*

W. Fay, P. E. Bock, I. Verhamme, 2001, The Journal of Biological Chemistry.

Non-identity of human plasma lysozyme and 4-methylumbelliferyl-tetra-N-acetyl-beta-D-chitotetraoside hydrolase.

I. Verhamme, T. Inaba, J. Brouwer, 1988, The International journal of biochemistry.

Fluorescent reporters of thrombin, heparin cofactor II, and heparin binding in a ternary complex.

I. Verhamme, 2012, Analytical biochemistry.

Inhibitory mechanism of serpins: loop insertion forces acylation of plasminogen activator by plasminogen activator inhibitor-1.

J. Shore, I. Verhamme, J. Kvassman, 1998, Biochemistry.

A novel antithrombin domain dictates the journey's end of a proteinase

I. Verhamme, 2017, The Journal of Biological Chemistry.

Analogs of Human Plasminogen That Are Labeled with Fluorescence Probes at the Catalytic Site of the Zymogen

S. Olson, M. Bernardo, P. E. Bock, 1996, The Journal of Biological Chemistry.

Rapid Binding of Plasminogen to Streptokinase in a Catalytic Complex Reveals a Three-step Mechanism*

P. E. Bock, I. Verhamme, P. Bock, 2014, The Journal of Biological Chemistry.

Rapid-reaction Kinetic Characterization of the Pathway of Streptokinase-Plasmin Catalytic Complex Formation*

P. E. Bock, I. Verhamme, P. Bock, 2008, Journal of Biological Chemistry.

Binding of the COOH-terminal Lysine Residue of Streptokinase to Plasmin(ogen) Kringles Enhances Formation of the Streptokinase·Plasmin(ogen) Catalytic Complexes*

P. Panizzi, P. E. Bock, I. Verhamme, 2006, Journal of Biological Chemistry.

Resolution of Conformational Activation in the Kinetic Mechanism of Plasminogen Activation by Streptokinase*

P. E. Bock, I. Verhamme, P. D. Boxrud, 2004, Journal of Biological Chemistry.

The mechanism underlying activation of factor IX by factor XIa.

J. Emsley, I. Verhamme, S. P. Bajaj, 2014, Thrombosis research.

A Sequential Mechanism for Exosite-mediated Factor IX Activation by Factor XIa*

S. Bajaj, I. Verhamme, S. P. Bajaj, 2012, The Journal of Biological Chemistry.

Ionic-strength-dependent substrate inhibition of the lysis of Micrococcus luteus by hen egg-white lysozyme.

A. Lauwers, I. Verhamme, G. V. Van Dedem, 1988, European journal of biochemistry.

Protease Activity in Single-Chain Prekallikrein.

A. Kaplan, I. Verhamme, B. Mohammed, 2019, Blood.

A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain.

A. Gruber, S. Kundu, K. McCrae, 2019, Blood.

Generation and characterization of aptamers targeting factor XIa.

B. Sullenger, I. Verhamme, R. Woodruff, 2017, Thrombosis research.

Evidence for factor IX‐independent roles for factor XIa in blood coagulation

O. Umunakwe, A. Gruber, I. Verhamme, 2013, Journal of thrombosis and haemostasis : JTH.

Kinetic Investigation of the Inhibition of Lysozyme by Heparin a

A. Lauwers, I. Verhamme, G. W. K. Dedem, 1989 .

Exosite-mediated Substrate Recognition of Factor IX by Factor XIa

I. Verhamme, D. Gailani, T. Ogawa, 2005, Journal of Biological Chemistry.

Glycosaminoglycan-binding properties and kinetic characterization of human heparin cofactor II expressed in Escherichia coli.

D. Friedman, Diana R. Arnett, I. Verhamme, 2010, Analytical biochemistry.

Identification of Tissue-type Plasminogen Activator-specific Plasminogen Activator Inhibitor-1 Mutants

D. Lawrence, D. Ginsburg, J. Shore, 1995, The Journal of Biological Chemistry.

Accelerated Conversion of Human Plasminogen Activator Inhibitor-1 to Its Latent Form by Antibody Binding*

P. Declerck, J. Shore, D. Day, 1999, The Journal of Biological Chemistry.

Analysis of the factor XI variant Arg184Gly suggests a structural basis for factor IX binding to factor XIa

J. Emsley, I. Verhamme, S. P. Bajaj, 2013, Journal of thrombosis and haemostasis : JTH.

Binding of Exosite Ligands to Human Thrombin RE-EVALUATION OF ALLOSTERIC LINKAGE BETWEEN THROMBIN EXOSITES I AND II*

S. Olson, I. Verhamme, D. Tollefsen, 2002 .

Model for surface-dependent factor XII activation: the roles of factor XII heavy chain domains

O. McCarty, R. Law, I. Verhamme, 2022, Blood advances.

A non‐circulating pool of factor XI associated with glycosaminoglycans in mice

O. McCarty, A. Gruber, J. Emsley, 2019, Journal of thrombosis and haemostasis : JTH.

Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin

J. Meiler, P. Panizzi, I. Verhamme, 2020, The Journal of Biological Chemistry.

Activation of factor XI by products of prothrombin activation.

I. Verhamme, J. Sheehan, D. Gailani, 2011, Blood.

Pathogen activators of plasminogen

I. Verhamme, P. Bock, Peter R. Panizzi, 2015, Journal of thrombosis and haemostasis : JTH.

AI is a viable alternative to high throughput screening: a 318-target study

Eva M García-Cuesta, Frederick S. Vizeacoumar, Stephen J. Capuzzi, 2024, Scientific reports.

Resolution of Michaelis complex, acylation, and conformational change steps in the reactions of the serpin, plasminogen activator inhibitor-1, with tissue plasminogen activator and trypsin.

S. Olson, J. Shore, D. Day, 2001, Biochemistry.