S. Raja

发表

Heparin Enhances the Specificity of Antithrombin for Thrombin and Factor Xa Independent of the Reactive Center Loop Sequence

S. Olson, Y. Chuang, R. Swanson, 2001, The Journal of Biological Chemistry.

A Novel Mechanism for Protein Delivery

M. Belting, R. Dressel, C. Menaa, 2005, Journal of Biological Chemistry.

Mechanism by Which Exosites Promote the Inhibition of Blood Coagulation Proteases by Heparin-activated Antithrombin*

S. Olson, R. Swanson, S. Raja, 2007, Journal of Biological Chemistry.

Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src@

Byung Min Chung, Chun Tu, V. Band, 2009, BMC Cell Biology.

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.

J. Trapani, E. Podack, S. Raja, 2002, Immunity.

Continuous requirement of ErbB2 kinase activity for loss of cell polarity and lumen formation in a novel ErbB2/Neu-driven murine cell line model of metastatic breast cancer

Lei Duan, V. Band, M. Dimri, 2011, Journal of carcinogenesis.

Granzyme-mediated Cytotoxicity Does Not Involve the Mannose 6-Phosphate Receptors on Target Cells*

K. von Figura, R. Dressel, S. Raja, 2004, Journal of Biological Chemistry.

Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance

V. Band, H. Band, M. Naramura, 2011, Journal of carcinogenesis.

NF‐κB protects from the lysosomal pathway of cell death

M. Peter, Justine C. Lee, D. Brömme, 2003, The EMBO Journal.

Encapsulation of Poorly Soluble Drugs in Polymer-Drug Conjugates: Effect of Dual-Drug Nanoformulations on Cancer Therapy

H. Band, S. Vinogradov, S. Raja, 2014, Pharmaceutical Research.

Glycosylphosphatidylinositol Anchors of Membrane Glycoproteins Are Binding Determinants for the Channel-forming Toxin Aerolysin*

D. Diep, S. Raja, K. Nelson, 1998, The Journal of Biological Chemistry.

Lysine 114 of Antithrombin Is of Crucial Importance for the Affinity and Kinetics of Heparin Pentasaccharide Binding*

S. Olson, I. Björk, S. Raja, 2001, The Journal of Biological Chemistry.

Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis

C. Gabay, M. Simon, S. Sprague, 2017, Arthritis & rheumatology.

Human and mouse granzyme A induce a proinflammatory cytokine response.

Lianfa Shi, M. Freudenberg, M. Simon, 2008, Immunity.

The Glycosylphosphatidylinositol-anchored Surface Glycoprotein Thy-1 Is a Receptor for the Channel-forming Toxin Aerolysin*

S. Raja, K. Nelson, J. Buckley, 1997, The Journal of Biological Chemistry.

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

Yong J. Lee, S. Raja, C. Froelich, 2003, The Journal of cell biology.

Granzyme B-mediated apoptosis – the elephant and the blind men?

S. Raja, C. Froelich, S. Metkar, 2004, Cell Death and Differentiation.

Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.

S. Raja, C. Froelich, S. Metkar, 2003, Current opinion in immunology.

NF-kappaB protects from the lysosomal pathway of cell death.

M. Peter, Justine C. Lee, D. Brömme, 2003, The EMBO journal.

High-throughput compatible fluorescence resonance energy transfer-based assay to identify small molecule inhibitors of AMSH deubiquitinase activity.

C. Das, A. Natarajan, S. Raja, 2013, Analytical biochemistry.

The antithrombin P1 residue is important for target proteinase specificity but not for heparin activation of the serpin. Characterization of P1 antithrombin variants with altered proteinase specificity but normal heparin activation.

S. Olson, Y. Chuang, R. Swanson, 2001, Biochemistry.

ESCRT proteins

V. Band, H. Band, K. Wagner, 2011, Bioarchitecture.

Deletion of P1 Arginine in a Novel Antithrombin Variant (Antithrombin London) Abolishes Inhibitory Activity but Enhances Heparin Affinity and Is Associated with Early Onset Thrombosis*

S. Olson, M. Laffan, D. Lane, 2003, The Journal of Biological Chemistry.

Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide.

S. Stupp, V. Cryns, V. Band, 2010, Cancer research.

A survey of dermatophytosis in animals in Madras, India.

S. Raja, S. Ranganathan, S. Balajee, 1997, Mycopathologia.

Movement of a loop in domain 3 of aerolysin is required for channel formation.

J. Rossjohn, M. Parker, S. Feil, 1998, Biochemistry.

A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells

V. Band, M. Dimri, H. Band, 2008, Cancer biology & therapy.

Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases.

Lin Dong, Nicholas Y. Palermo, G. Borgstahl, 2013, Biochimica et biophysica acta.

Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers

Lei Duan, V. Band, H. Band, 2011, Cancer biology & therapy.

Distinct Roles for Rho Versus Rac/Cdc42 GTPases Downstream of Vav2 in Regulating Mammary Epithelial Acinar Architecture*

Lei Duan, V. Band, M. Dimri, 2009, The Journal of Biological Chemistry.

A Kinase Inhibitor Screen Reveals Protein Kinase C-dependent Endocytic Recycling of ErbB2 in Breast Cancer Cells*

V. Band, H. Band, D. Kelly, 2014, The Journal of Biological Chemistry.

Loss of the Nuclear Pool of Ubiquitin Ligase CHIP/STUB1 in Breast Cancer Unleashes the MZF1-Cathepsin Pro-oncogenic Program.

J. Meza, N. Mishra, E. Rakha, 2018, Cancer research.

Localization and environment of tryptophans in soluble and membrane-bound states of a pore-forming toxin from Staphylococcus aureus.

A. K. Lala, A. Chattopadhyay, S. Rawat, 1999, Biophysical journal.

RE SE EE DUB Proteasome Lysosome MVB / Late Endosome ESCRT Degradative Pathway EGF CblUbiquitin EGFR Associated Protiens Recycling Pathway

Nicholas Y. Palermo, G. Borgstahl, V. Band, 2012 .

Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders

V. Band, H. Band, M. Sattler, 2011, Oncotarget.

Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition

V. Band, H. Band, T. Bronich, 2016, Oncotarget.

Cytotoxic Cell Granule-mediated Apoptosis

Borries Demeler, Umesh R. Desai, Christopher J. Froelich, 2002, The Journal of Biological Chemistry.

Polypeptide-based nanogels co-encapsulating a synergistic combination of doxorubicin with 17-AAG show potent anti-tumor activity in ErbB2-driven breast cancer models.

V. Band, H. Band, T. Bronich, 2015, Journal of controlled release : official journal of the Controlled Release Society.

CHIP/STUB1 Ubiquitin Ligase Functions as a Negative Regulator of ErbB2 by Promoting Its Early Post-Biosynthesis Degradation

V. Band, H. Band, S. Raja, 2021, Cancers.

Negative Regulation of EGFR-Vav2 Signaling Axis by Cbl Ubiquitin Ligase Controls EGF Receptor-mediated Epithelial Cell Adherens Junction Dynamics and Cell Migration

Lei Duan, V. Band, M. Dimri, 2010, The Journal of Biological Chemistry.

A Comprehensive, Multi-Scale Dynamical Model of ErbB Receptor Signal Transduction in Human Mammary Epithelial Cells

Tomáš Helikar, Jim A. Rogers, T. Helikar, 2013, PloS one.