W. Groutas

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Inhibition of human leukocyte proteinase 3 by a novel recombinant serine proteinase inhibitor (LEX032).

W. Groutas, S. Ruan, R. Kuang, 1997, Biochemical and biophysical research communications.

Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses

K. Battaile, W. Groutas, Yunjeong Kim, 2012, Journal of Virology.

Structure-based design and optimization of dipeptidyl inhibitors of norovirus 3CL protease

D. Hua, W. Groutas, Yunjeong Kim, 2014 .

Design, synthesis, and in vitro evaluation of potential West Nile virus protease inhibitors based on the 1-oxo-1,2,3,4-tetrahydroisoquinoline and 1-oxo-1,2-dihydroisoquinoline scaffolds.

G. Lushington, R. Padmanabhan, W. Groutas, 2010, Journal of combinatorial chemistry.

Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

N. Pedersen, D. Hua, Hongwei Liu, 2016, PLoS pathogens.

Potent inhibition of feline coronaviruses with peptidyl compounds targeting coronavirus 3C-like protease

W. Groutas, Yunjeong Kim, S. R. Mandadapu, 2012, Antiviral Research.

Structure-Guided Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease.

G. Lushington, K. Battaile, W. Groutas, 2020, Journal of medicinal chemistry.

Structure-Guided Design of Conformationally-Constrained Cyclohexane Inhibitors of SARS-CoV-2 3CL Protease

J. Zheng, S. Perlman, K. Battaile, 2021 .

Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies

S. Perlman, K. Battaile, W. Groutas, 2021, Journal of medicinal chemistry.

Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

S. Perlman, D. Meyerholz, K. Battaile, 2021, Proceedings of the National Academy of Sciences.

Putative structural rearrangements associated with the interaction of macrocyclic inhibitors with norovirus 3CL protease

K. Battaile, W. Groutas, Yunjeong Kim, 2019, Proteins.

Structure-Guided Design of Potent Spirocyclic Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3C-like Protease

K. Battaile, W. Groutas, Yunjeong Kim, 2022, Journal of medicinal chemistry.

Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors

D. Hua, W. Groutas, Yunjeong Kim, 2013, Bioorganic & Medicinal Chemistry Letters.

Inhibitors of human neutrophil cathepsin G: structural and biochemical studies.

W. Groutas, J. Epp, M. Brubaker, 1992, Archives of biochemistry and biophysics.

Inhibition of human leukocyte elastase by phosphate esters of N-hydroxysuccinimide and its derivatives: direct observation of a phosphorylated enzyme by 31P nuclear magnetic resonance spectroscopy.

W. Groutas, M. Brubaker, R. Venkataraman, 1991, Biochemistry.

Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils.

H. Huang, W. Groutas, J. Epp, 1994, Biochimica et biophysica acta.

Potent inhibition of Norwalk virus by cyclic sulfamide derivatives.

W. Groutas, Yunjeong Kim, K. Tiew, 2011, Bioorganic & medicinal chemistry.

Formation of an unusual product in the reaction of a 1,2,5‐thiadiazolidine 1,1‐dioxide‐derived thioether with sulfuryl chloride

W. Groutas, D. Eichhorn, E. Talaty, 2009 .

Inhibition of human leukocyte elastase by derivatives of N-hydroxysuccinimide. A structure-activity-relationship study.

W. Groutas, James Crowley, M. Brubaker, 1989, Journal of medicinal chemistry.

Inhibition of serine proteases by a new class of cyclosulfamide-based carbamylating agents.

S. Mohan, T. Williams, W. Groutas, 2008, Archives of biochemistry and biophysics.

Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase.

W. Groutas, R. Kuang, Dengfeng Dou, 2010, Bioorganic & medicinal chemistry.

Inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1 dioxide-based sulfonamides.

W. Groutas, K. Alliston, Dengfeng Dou, 2008, Bioorganic & medicinal chemistry.

Potential mechanism-based inhibitors of proteolytic enzymes

W. Groutas, J. Epp, M. Brubaker, 1992 .

Inhibitors of human neutrophil elastase based on a highly functionalized N-amino-4-imidazolidinone scaffold.

W. Groutas, K. Alliston, Dengfeng Dou, 2010, European journal of medicinal chemistry.

Potent inhibition of human leukocyte elastase by 1,2,5-thiadiazolidin-3-one 1,1 dioxide-based sulfonamide derivatives.

Yue H. Li, W. Groutas, K. Alliston, 2004, Archives of biochemistry and biophysics.

Potent inhibition of serine proteases by heterocyclic sulfide derivatives of 1,2,5-thiadiazolidin-3-one 1,1 dioxide.

W. Groutas, R. Kuang, H. Chan, 2000, Bioorganic & medicinal chemistry.

Serendipitous discovery of an unexpected rearrangement leads to two new classes of potential protease inhibitors.

J. Hoidal, W. Groutas, K. Alliston, 2004, Bioorganic & medicinal chemistry.

Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners.

O. Prakash, W. Groutas, R. Kuang, 1996, Bioorganic & medicinal chemistry.

Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study.

W. Groutas, E. H. Kim, J. Epp, 1995, Bioorganic & medicinal chemistry.

3-(Alkylthio)-N-hydroxysuccinimide derivatives: potent inhibitors of human leukocyte elastase.

W. Groutas, J. Epp, M. Brubaker, 1993, Biochimica et biophysica acta.

Potent Protease Inhibitors of Highly Pathogenic Lagoviruses: Rabbit Hemorrhagic Disease Virus and European Brown Hare Syndrome Virus

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2022, Microbiology spectrum.

Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies

G. Lushington, K. Battaile, W. Groutas, 2016, European Journal of Medicinal Chemistry.

Use of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide and isothiazolidin-3-one 1,1 dioxide scaffolds in the design of potent inhibitors of serine proteinases.

W. Groutas, S. Ruan, R. Kuang, 1998, Bioorganic & medicinal chemistry letters.

Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives.

R. Calderone, W. Groutas, K. Tiew, 2011, Bioorganic & medicinal chemistry.

Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2015, Antiviral Research.

Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis

N. Pedersen, Hongwei Liu, W. Groutas, 2017, Journal of feline medicine and surgery.

Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates.

W. Groutas, S. Ruan, R. Kuang, 2000, Bioorganic & medicinal chemistry.

Potent and specific inhibition of human leukocyte elastase, cathepsin G and proteinase 3 by sulfone derivatives employing the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold.

W. Groutas, S. Ruan, R. Kuang, 1998, Bioorganic & medicinal chemistry.

The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.

J. Hoidal, W. Groutas, R. Kuang, 1995, Bioorganic & medicinal chemistry.

A general approach toward the design of inhibitors of serine proteinases: inhibition of human leukocyte elastase by substituted dihydrouracils

W. Groutas, J. Epp, M. Brubaker, 1992 .

Facile redox formation of a 3-substituted maleimide from a 3-substituted N-hydroxysuccinimide

W. Groutas, M. Brubaker, R. Venkataraman, 1991 .

Inhibitors of leukocyte elastase and leukocyte Cathepsin G. Agents for the treatment of emphysema and related ailments

W. Groutas, 1987, Medicinal research reviews.

Potent norovirus inhibitors based on the acyclic sulfamide scaffold.

W. Groutas, Yunjeong Kim, K. Tiew, 2012, Bioorganic & medicinal chemistry.

Repurposing an inhibitor of ribosomal biogenesis with broad anti-fungal activity

R. Calderone, Dongmei Li, W. Groutas, 2017, Scientific Reports.

Inactivation of leukocyte elastase by aryl azolides and sulfonate salts. Structure-activity relationship studies.

M. Zandler, W. Groutas, James Crowley, 1986, Journal of medicinal chemistry.

Recent developments in the design of mechanism-based and alternate substrate inhibitors of serine proteases.

W. Groutas, Jiaying Zhong, 2004, Current topics in medicinal chemistry.

Noncovalent inhibitors of human leukocyte elastase based on the 4-imidazolidinone scaffold.

W. Groutas, K. Alliston, Liuqing Wei, 2003, Bioorganic & medicinal chemistry.

A General Inhibitor Scaffold for Serine Proteases with a (Chymo)trypsin-Like Fold: Solution-Phase Construction and Evaluation of the First Series of Libraries of Mechanism-Based Inhibitors

N. Schechter, W. Groutas, S. Ruan, 1999 .

Structure-based design of a general class of mechanism-based inhibitors of the serine proteinases employing a novel amino acid-derived heterocyclic scaffold.

O. Prakash, W. Groutas, S. Ruan, 1997, Biochemistry.

Human neutrophil proteinase 3: mapping of the substrate binding site using peptidyl thiobenzyl esters.

J. Hoidal, W. Groutas, N. Rao, 1992, Biochemical and biophysical research communications.

Specific inhibition of human leukocyte elastase by substituted alpha-pyrones

W. Groutas, W. Abrams, M. Moi, 1984, Experientia.

Mechanism-based inhibitors of elastase.

T. Ocain, J. Frankson, W. Groutas, 1980, Biochemical and biophysical research communications.

X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives.

Yasufumi Yamamoto, T. Williams, W. Groutas, 2008, Journal of medicinal chemistry.

Synthetic Applications of Cyanotrimethylsilane, lodotrimethylsilane, Azidotrimethylsilane, and Methylthiotrimethylsilane

W. Groutas, D. Felker, 1980 .

Hydantoin derivatives. A new class of inhibitors of human leukocyte elastase.

W. Groutas, M. A. Stanga, J. C. Castrisos, 1990, Journal of enzyme inhibition.

Design, synthesis and characterization of novel 1,2-benzisothiazol-3(2H)-one and 1,3,4-oxadiazole hybrid derivatives: potent inhibitors of Dengue and West Nile virus NS2B/NS3 proteases.

G. Lushington, R. Padmanabhan, W. Groutas, 2013, Bioorganic & medicinal chemistry.

Substituted 2-pyrones, 2-pyridones, and other congeners of elasnin as potential agents for the treatment of chronic obstructive lung diseases.

W. Groutas, M. Moi, T. Huang, 1985, Journal of medicinal chemistry.

Inhibition of neurotoxic esterase in vitro by novel carbamates.

J. Ambroso, R. Richardson, W. Groutas, 1997, Toxicology and applied pharmacology.

Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.

G. Lushington, W. Groutas, Yunjeong Kim, 2013, Bioorganic & medicinal chemistry letters.

Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors.

D. Hua, W. Groutas, Yunjeong Kim, 2013, Bioorganic & medicinal chemistry letters.

Mechanism-based inactivation of human leukocyte elastase via an enzyme-induced sulfonamide fragmentation process.

M. V. van Stipdonk, W. Groutas, K. Alliston, 2004, Archives of biochemistry and biophysics.

α-Cyanation of Tertiary Amines

P. Portoghese, W. Groutas, M. Essawi, 1980 .

t‐Butyldimethylsilyl Cyanide

W. Groutas, 2001 .

Inhibition of serine proteases by functionalized sulfonamides coupled to the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold.

W. Groutas, S. Ruan, R. Kuang, 2001, Bioorganic & medicinal chemistry.

The Lossen rearrangement in biological systems. Inactivation of leukocyte elastase and alpha-chymotrypsin by (dl)-3-benzyl-N-(methanesulfonyloxy) succinimide.

W. Groutas, James Crowley, M. Brubaker, 1986, Biochemical and biophysical research communications.

Utilization of the 1,2,3,5-thiatriazolidin-3-one 1,1-dioxide scaffold in the design of potential inhibitors of human neutrophil proteinase 3.

G. Lushington, W. Groutas, K. Alliston, 2010, Bioorganic & medicinal chemistry.

Inhibition of human leukocyte elastase and cathepsin G by isoxazoline derivatives

W. Groutas, J. Epp, M. Brubaker, 1992 .

Synthesis of Functionalized Alpha-methylene Lactones

W. Groutas, G. Meitzner, D. Magnin, 1980 .

Efficient inhibition of human leukocyte elastase and cathepsin G by saccharin derivatives.

H. Huang, W. Groutas, J. Epp, 1993, Journal of medicinal chemistry.

Synthesis of Aromatic a-Methylene Lactones

W. Groutas, D. Magnin, D. Felker, 1980 .

Design, synthesis, and in vitro evaluation of inhibitors of human leukocyte elastase based on a functionalized cyclic sulfamide scaffold.

W. Groutas, K. Alliston, Xiangdong Gan, 2004, Bioorganic & medicinal chemistry.

Antifungal drug discovery: the process and outcomes.

Dongmei Li, R. Calderone, F. Gay-andrieu, 2014, Future microbiology.

Anti-norovirus therapeutics: a patent review (2010-2015)

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2016, Expert opinion on therapeutic patents.

Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.

H. Huang, J. Hoidal, W. Groutas, 1995, Bioorganic & medicinal chemistry.

Heterocyclic inhibitors of human leukocyte elastase: 3-Hydroxypyridazopyrimidine, 3-hydroxypyridopyrimidine and 3-hydroxyquinazoline-2,4-1H,3H0dione derivatives

W. Groutas, R. Kuang, J. Epp, 1993 .

13C NMR evidence for an enzyme-induced Lossen rearrangement in the mechanism-based inactivation of .alpha.-chymotrypsin by 3-benzyl-N-((methylsulfonyl)oxy)succinimide

W. Groutas, M. Brubaker, M. A. Stanga, 1989 .

Substituted 2‐Pyrones and 5,6‐Dihydropyrones

W. Groutas, M. Moi, T. Huang, 1985 .

Inhibition of noroviruses by piperazine derivatives.

Guijia He, W. Groutas, Yunjeong Kim, 2012, Bioorganic & medicinal chemistry letters.

Substituted 2-pyrones and 5,6-dihydropyrones as inhibitors of the serine proteases

W. Groutas, M. Moi, T. Huang, 1985 .

Substituted 3-oxo-1,2,5-thiadiazolidine 1,1-dioxides: a new class of potential mechanism-based inhibitors of human leukocyte elastase and cathepsin G.

W. Groutas, R. Kuang, R. Venkataraman, 1994, Biochemical and biophysical research communications.

Amino Acid-Derived 1,2-Benzisothiazolinone Derivatives as Novel Small-Molecule Antifungal Inhibitors: Identification of Potential Genetic Targets

R. Calderone, F. Gay-andrieu, W. Groutas, 2012, Antimicrobial Agents and Chemotherapy.

Potent protease inhibitors of deadly lagoviruses: rabbit hemorrhagic disease virus and European brown hare syndrome virus

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2022, bioRxiv.

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice

S. Perlman, D. Meyerholz, K. Battaile, 2020, Science Translational Medicine.

Protease inhibitors broadly effective against feline, ferret and mink coronaviruses

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2018, Antiviral Research.

Neutrophil elastase inhibitors

W. Groutas, K. Alliston, Dengfeng Dou, 2011, Expert opinion on therapeutic patents.

Structural and inhibitor studies of norovirus 3C-like proteases.

D. Takahashi, W. Groutas, Yunjeong Kim, 2013, Virus research.

Cyclosulfamide-based derivatives as inhibitors of noroviruses.

W. Groutas, Yunjeong Kim, S. R. Mandadapu, 2012, European journal of medicinal chemistry.

Human chymase inhibitors based on the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold.

N. Schechter, W. Groutas, P. Huang, 1999, Bioorganic & medicinal chemistry letters.

Recent Advances in the Discovery of Norovirus Therapeutics.

W. Groutas, Yunjeong Kim, Kyeong-Ok Chang, 2015, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.

W. Groutas, Yunjeong Kim, K. Alliston, 2017, Journal of medicinal chemistry.

SYNTHETIC APPLICATIONS OF CYANOTRIMETHYLSILANE, IODOTRIMETHYLSILANE, AZIDOTRIMETHYLSILANE, AND METHYLTHIOTRIMETHYLSILANE

W. Groutas, D. Felker, 1981 .

Potential protease inhibitors based on a functionalized cyclic sulfamide scaffold.

W. Groutas, K. Alliston, Zhong Lai, 2004, Journal of combinatorial chemistry.

Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor

N. Pedersen, Hongwei Liu, W. Groutas, 2019, Veterinary Microbiology.

Broad-Spectrum Inhibitors against 3C-Like Proteases of Feline Coronaviruses and Feline Caliciviruses

D. Hua, S. Narayanan, W. Groutas, 2015, Journal of Virology.

Antiviral Drug Discovery: Norovirus Proteases and Development of Inhibitors

W. Groutas, Yunjeong Kim, S. Lovell, 2019, Viruses.

Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus

G. Lushington, D. Hua, W. Groutas, 2013, Bioorganic & Medicinal Chemistry Letters.

Affinity chromatography of glucose dehydrogenase

W. R. Carper, W. Groutas, D. Coffin, 1988, Experientia.

Inhibition of Dengue virus and West Nile virus proteases by click chemistry-derived benz[d]isothiazol-3(2H)-one derivatives.

G. Lushington, R. Padmanabhan, W. Groutas, 2012, Bioorganic & medicinal chemistry.

Synthesis, X-ray crystallographic determination, and opioid activity of erythro-5-methylmethadone enantiomers. Evidence which suggests that mu and delta opioid receptors possess different stereochemical requirements.

D. L. Larson, J. Poupaert, W. Duax, 1982, Journal of medicinal chemistry.

Repurposing an inhibitor of ribosomal biogenesis with broad anti-fungal activity

R. Calderone, Dongmei Li, W. Groutas, 2017, Scientific Reports.

Inhibitors of Dengue virus and West Nile virus proteases based on the aminobenzamide scaffold.

G. Lushington, R. Padmanabhan, W. Groutas, 2012, Bioorganic & medicinal chemistry.

Design, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease.

G. Lushington, W. Groutas, Yunjeong Kim, 2011, Bioorganic & medicinal chemistry letters.

Structure-Guided Design of Conformationally Constrained Cyclohexane Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 3CL Protease

S. Perlman, K. Battaile, W. Groutas, 2021, Journal of medicinal chemistry.

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

S. Perlman, Anthony R. Fehr, G. Lushington, 2018, European Journal of Medicinal Chemistry.

Tc-99m-labeled polystyrene and cellulose macromolecules: agents for gastrointestinal scintigraphy.

W. Groutas, M. Theodorakis, T. W. Whitlock, 1982, Journal of Nuclear Medicine.

Structure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studies.

K. Battaile, W. Groutas, Yunjeong Kim, 2015, Journal of medicinal chemistry.

Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies.

K. Battaile, Alexandra J Machen, W. Groutas, 2022, ACS pharmacology & translational science.

Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles.

G. Lushington, W. Groutas, Yunjeong Kim, 2012, Bioorganic & medicinal chemistry letters.

Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors.

G. Lushington, K. Battaile, W. Groutas, 2017, European journal of medicinal chemistry.

Design and synthesis of inhibitors of noroviruses by scaffold hopping.

W. Groutas, Yunjeong Kim, S. R. Mandadapu, 2011, Bioorganic & medicinal chemistry.

Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV)

K. Battaile, Alexandra J Machen, W. Groutas, 2023, European Journal of Medicinal Chemistry.

Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.

G. Lushington, K. Battaile, W. Groutas, 2017, European journal of medicinal chemistry.

Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease.

G. Lushington, K. Battaile, W. Groutas, 2016, Journal of medicinal chemistry.

Dual-action inhibitors of proteolytic enzymes: potential therapeutic agents for cystic fibrosis and related ailments.

W. Groutas, J. Epp, R. Venkataraman, 1993, Bioorganic & medicinal chemistry.

Enantioselective inhibition of human leukocyte elastase.

W. Groutas, M. Brubaker, R. Venkataraman, 1992, Archives of biochemistry and biophysics.

Dual function inhibitors of relevance to chronic obstructive pulmonary disease.

W. Groutas, K. Alliston, Dengfeng Dou, 2011, Bioorganic & medicinal chemistry letters.

Post-infection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection

S. Perlman, D. Meyerholz, K. Battaile, 2021, bioRxiv.

Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease.

G. Lushington, K. Battaile, W. Groutas, 2016, Journal of medicinal chemistry.

Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.

G. Lushington, K. Battaile, W. Groutas, 2018, European journal of medicinal chemistry.

Correction: Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

N. Pedersen, D. Hua, Hongwei Liu, 2016, PLoS pathogens.