N. Kono

发表

Purification and properties of rabbit erythrocyte phosphofructokinase.

K. Uyeda, S. Tarui, N. Kono, 1972, The Journal of biological chemistry.

Enzymatic basis for the coexistence of myopathy and hemolytic disease in inherited muscle phosphofructokinase deficiency.

S. Tarui, N. Kono, T. Nasu, 1969, Biochemical and biophysical research communications.

Impaired ketogenesis in patients with adult-type citrullinemia.

Y. Matsuzawa, S. Kawata, S. Tarui, 1994, Gastroenterology.

Clinical utility of somatosensory evoked potentials in diabetes mellitus.

S. Tarui, N. Kono, M. Takahashi, 1989, Diabetes research and clinical practice.

Clinical evaluation of biosynthetic glucagon treatment for recovery from hypoglycemia developed in diabetic patients. The GL-G Hypoglycemia Study Group.

T. Hanafusa, M. Namba, S. Tarui, 1993, Diabetes research and clinical practice.

Autoimmune endocrine disease induced by recombinant interferon-alpha therapy for chronic active type C hepatitis.

Y. Matsuzawa, A. Imagawa, T. Hanafusa, 1995, The Journal of clinical endocrinology and metabolism.

Treatment of Kearns‐Sayre syndrome with coenzyme Q10

S. Yorifuji, S. Tarui, N. Kono, 1986, Neurology.

A comparative study on glucagon effect between mcardle disease and tarui disease

I. Mineo, S. Tarui, N. Kono, 1984, Muscle & nerve.

Metabolic basis of improved exercise tolerance

J. Kang, I. Mineo, S. Tarui, 1984, Neurology.

Enhanced release of ammonia and hypoxanthine from exercising muscles in patients with idiopathic hypoparathyroidism

I. Mineo, S. Tarui, N. Kono, 1987, Muscle & nerve.

Excess purine degradation in exercising muscles of patients with glycogen storage disease types V and VII.

I. Mineo, N. Kono, K. Nonaka, 1985, The Journal of clinical investigation.

Glucose infusion paradoxically accelerates degradation of adenine nucleotide in working muscle of patients with glycogen storage disease type VII

Y. Matsuzawa, I. Mineo, N. Kono, 1995, Neurology.

Transthyretin (prealbumin) in the pancreas and sera of newly diagnosed type I (insulin-dependent) diabetic patients.

T. Hanafusa, S. Kawata, S. Tamura, 1992, The Journal of clinical endocrinology and metabolism.

Improvement of abnormal pyruvate metabolism and cardiac conduction defect with coenzyme Ql0 in Kearns‐Sayre syndrome

S. Yorifuji, S. Tarui, N. Kono, 1985, Neurology.

Rat-liver-type phosphofructokinase mRNA. Structure, tissue distribution and regulation.

T. Tanaka, T. Noguchi, K. Hotta, 1991, European journal of biochemistry.

Prognostic Significance of Serum Soluble Interleukin-2 Receptor Level in Non-Hodgkin's Lymphoma: A Single Center Study in Japan

Y. Kanda, A. Togawa, N. Kono, 2000, Leukemia & lymphoma.

Histopathologic Study of Lymphocytic Infiltration the Pancreas Shows in Japanese Patients a Characterist with IDDM

A. Imagawa, T. Hanafusa, N. Kono, 2006 .

Occurrence of IDDM during interferon therapy for chronic viral hepatitis.

Y. Matsuzawa, A. Imagawa, T. Hanafusa, 1994, Diabetes research and clinical practice.

Altered expression of carnitine palmitoyltransferase II in liver, muscle, and heart of mouse strain with juvenile visceral steatosis.

Y. Matsuzawa, T. Saheki, K. Hotta, 1996, Biochimica et biophysica acta.

Disordered expression of glycolytic and gluconeogenic liver enzymes of juvenile visceral steatosis mice with systemic carnitine deficiency.

Y. Matsuzawa, T. Saheki, T. Noguchi, 1996, Diabetes research and clinical practice.

Disordered expression of hepatic glycolytic and gluconeogenic enzymes in Otsuka Long-Evans Tokushima fatty rats with spontanteous long-term hyperglycemia.

Y. Matsuzawa, R. Shingu, T. Noguchi, 1996, Biochimica et biophysica acta.

Tissue specificity in expression and alternative RNA splicing of human phosphofructokinase-M and -L genes.

T. Tanaka, T. Noguchi, K. Hotta, 1990, Biochemical and biophysical research communications.

Evidence for alternative RNA splicing and possible alternative promoters in the human muscle phosphofructokinase gene at the 5' untranslated region.

T. Tanaka, T. Noguchi, S. Tarui, 1990, Biochemical and biophysical research communications.

Cloning of human muscle phosphofructokinase cDNA

T. Noguchi, S. Tarui, N. Kono, 1987, FEBS letters.

Morphological study of lipoprotein particles in the livers of ventromedial hypothalamus lesioned rats.

Y. Matsuzawa, S. Kawata, N. Kono, 1987, International journal of obesity.

Animal model of systemic carnitine deficiency: Analysis in C3H-H-2° strain of mouse associated with juvenile visceral steatosis

T. Saheki, S. Kawata, T. Koizumi, 1991 .

HLA-DQA1*1 contributes to resistance and A1*3 confers susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects

T. Tanaka, T. Noguchi, K. Yamagata, 1991, Diabetologia.

Myogenic hyperuricemia. A common pathophysiologic feature of glycogenosis types III, V, and VII.

H. Kiyokawa, I. Mineo, N. Kono, 1987, The New England journal of medicine.

Carnitine

N. Kono, 2018, Reactions Weekly.

Expression of class II major histocompatibility complex antigens on pancreatic B cells in the NOD mouse

T. Hanafusa, S. Tarui, N. Kono, 1987, Diabetologia.

No detectable cytomegalovirus and Epstein-Barr virus genomes in the pancreas of recent-onset IDDM patients

Y. Matsuzawa, K. Yamagata, T. Hanafusa, 1995, Diabetologia.

Retrovirus gag protein p30 in the islets of non-obese diabetic mice: relevance for pathogenesis of diabetes mellitus

M. Yutsudo, A. Hakura, T. Hanafusa, 1992, Diabetologia.

Dominant TCR alpha-chain clonotypes and interferon-gamma are expressed in the pancreas of patients with recent-onset insulin-dependent diabetes mellitus.

Y. Matsuzawa, T. Noguchi, K. Yamagata, 1996, Diabetes research and clinical practice.

Chicken liver phosphofructokinase. 3. Kinetics and allosteric properties.

K. Uyeda, N. Kono, 1973, The Journal of biological chemistry.

Histopathologic study of the pancreas shows a characteristic lymphocytic infiltration in Japanese patients with IDDM.

Y. Matsuzawa, A. Imagawa, T. Hanafusa, 1997, Endocrine journal.

Autoantibodies to the insulin receptor impair clearance of plasma endogenous insulin.

H. Kiyokawa, I. Mineo, N. Kono, 1989, Diabetes research and clinical practice.

Hyperinsulinemia due to impaired insulin clearance associated with fasting hypoglycemia and postprandial hyperglycemia: an analysis of a patient with antiinsulin receptor antibodies.

H. Kiyokawa, I. Mineo, N. Kono, 1989, The Journal of clinical endocrinology and metabolism.

Effects of glucagon on urinary excretion of urea and on plasma ammonia level in argininosuccinate synthetase deficiency

Y. Matsuzawa, M. Namba, S. Kawata, 2005, Journal of Gastroenterology.

Requirement of Fas for the Development of Autoimmune Diabetes in Nonobese Diabetic Mice

Y. Matsuzawa, S. Nagata, A. Imagawa, 1997, The Journal of experimental medicine.

Induction of Insulitis by Adoptive Transfer With L3T4+ Lyt2− T-Lymphocytes in T-Lymphocyte–Depleted NOD Mice

H. Fujiwara, T. Hanafusa, T. Hamaoka, 1988, Diabetes.

Nicotinamide and 3-aminobenzamide reduce interferon-gamma-induced class II MHC (HLA-DR and -DP) molecule expression on cultured human endothelial cells and fibroblasts.

T. Hanafusa, S. Tarui, N. Kono, 1991, Immunopharmacology and immunotoxicology.

EXAGGERATED INSULIN SECRETORY RESPONSE IN PATIENTS WITH INSULINOMAS TO MIDAGLIZOLE, A DRUG WITH α2‐ADRENERGIC BLOCKING ACTIVITY

T. Hanafusa, H. Kiyokawa, M. Namba, 1988, Clinical endocrinology.

HLA-DP and susceptibility to insulin-dependent diabetes mellitus in Japanese.

T. Tanaka, T. Noguchi, K. Yamagata, 1991, Tissue antigens.

Aspartic acid at position 57 of DQβ chain does not protect against Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects

T. Tanaka, T. Noguchi, K. Yamagata, 1989, Diabetologia.

Low glucose-1, 6-bisphosphate and high fructose-2, 6-bisphosphate concentrations in muscles of patients with glycogenosis types VII and V.

H. Kiyokawa, N. Kono, M. Kuwajima, 1991, Biochemical and biophysical research communications.

Presence of glucagon-(1-21)-Like immunoreactive substance in the dog small intestinal mucosa.

Y. Shinomura, M. Namba, S. Tarui, 1989, Biochemical and biophysical research communications.

Glucagonlike peptide-1(7-36)amide suppresses glucagon secretion and decreases cyclic AMP concentration in cultured In-R1-G9 cells.

Y. Matsuzawa, M. Namba, M. Tanaka, 1992, Biochemical and biophysical research communications.

Influence of daily drinking habits on ethanol-induced hyperuricemia.

Y. Matsuzawa, I. Mineo, N. Kono, 1994, Metabolism: clinical and experimental.

Alteration of Glycolytic Intermediary Metabolism in Erythrocytes During Diabetic Ketoacidosis and Its Recovery Phase

S. Tarui, N. Kono, M. Kuwajima, 1981, Diabetes.

Resistance of the peripheral nerve to ischemia in diabetic patients--an electrophysiological study.

S. Tarui, N. Kono, Y. Nakamura, 1988, Diabetes Research and Clinical Practice.

Chicken liver phosphofructokinase. I. Crystallization and physicochemical properties.

R. M. Oliver, K. Uyeda, N. Kono, 1973, The Journal of biological chemistry.

Decreases in hepatic fructose-2,6-bisphosphate level and fructose-6-phosphate,2-kinase activity in diabetic mice: a close relationship to the development of ketosis.

I. Mineo, N. Kono, K. Nonaka, 1984, Biochemical and biophysical research communications.

Structure of the entire human muscle phosphofructokinase-encoding gene: a two-promoter system.

T. Tanaka, T. Noguchi, K. Hotta, 1991, Gene.

Elevated antibody-dependent cell-mediated cytotoxicity and its inhibition by nicotinamide in the diabetic NOD mouse.

T. Hanafusa, N. Kono, J. Miyagawa, 1986, Immunology letters.

Two types of autoantibodies to adrenal medullary cells in type 1 (insulin-dependent) diabetic patients: prevalence, properties and implications.

T. Hanafusa, N. Kono, J. Miyagawa, 1991, Journal of autoimmunity.

Glucagonostatic and Insulinotropic Action of Glucagonlike Peptide I-(7–36)-Amide

M. Namba, S. Tarui, N. Kono, 1989, Diabetes.

MULTIPLE FORMS OF GLUCAGON-LIKE PEPTIDE-1 AND GLUCAGON-LIKE IMMUNOREACTIVITIES IN CANINE GASTROINTESTINAL TRACT AND THEIR RELEASE INTO CIRCULATION

M. Namba, S. Tarui, N. Kono, 1990 .

Trophic effect of glucagon-(1-21)-peptide on the isolated rat ileal mucosal cells.

M. Namba, S. Tarui, N. Kono, 1988, Biochemical and biophysical research communications.

Demonstration of Islet Cell Surface Antibodies in Sera of New Zealand Black Mice and Inhibitory Effect on Insulin Release

T. Hanafusa, S. Tarui, N. Kono, 1986, Diabetes.

DIFFERENTIATION OF B—CELLS FROM DUCTAL CELLS AND ACCELERATION OF THIS PROCESS BY NICOTINAMIDE: ULTRASTRUCTURAL STUDY ON THE NON-OBESE DIABETIC (NOD) MICE WITH OVERT DIABETES

Y. Matsuzawa, T. Hanafusa, M. Namba, 1997 .

Interferon-gamma reduces the thyroid peroxidase content of cultured human thyrocytes and inhibits its increase induced by thyrotropin.

T. Hanafusa, S. Tarui, N. Kono, 1992, The Journal of clinical endocrinology and metabolism.

Metabolism of pyrazinamide and allopurinol in hereditary xanthine oxidase deficiency.

K. Higashino, N. Kono, T. Yamamoto, 1989, Clinica chimica acta; international journal of clinical chemistry.

Chicken liver phosphofructokinase. II. Cold inactivation.

K. Uyeda, N. Kono, 1973, The Journal of biological chemistry.

Cloning and reporter analysis of human mitochondrial phosphoenolpyruvate carboxykinase gene promoter.

H. Nakajima, N. Kono, T. Yamasaki, 2004, Gene.

Hereditary xanthine oxidase deficiency consisting of at least two subgroups.

K. Higashino, N. Kono, T. Yamamoto, 1989, Advances in experimental medicine and biology.

Ultrastructural and immunocytochemical aspects of lymphocytic submandibulitis in the non-obese diabetic NOD mouse

T. Hanafusa, S. Tarui, N. Kono, 1986, Virchows Archiv. B, Cell pathology including molecular pathology.

Dominant TCR α-chain clonotypes and interferon-γ are expressed in the pancreas of patients with recent-onset insulin-dependent diabetes mellitus

Y. Matsuzawa, T. Noguchi, K. Yamagata, 1996 .

Erythrocyte glycolysis and its marked alterations by muscular exercise in type VII glycogenosis.

H. Kiyokawa, I. Mineo, N. Kono, 1988, Blood.

Cold labile phosphofructokinase.

K. Uyeda, N. Kono, 1971, Biochemical and biophysical research communications.

Effect of glucagon-(1-21)-peptide on secretin-stimulated pancreatic exocrine secretion in anesthetized dogs.

M. Namba, S. Tarui, N. Kono, 1989, Life sciences.

Hereditary and acquired abnormalities in erythrocyte phosphofructokinase activity: the close association with altered 2,3-diphosphoglycerate levels.

S. Tarui, N. Kono, M. Kuwajima, 1980, Hemoglobin.

Effects of the intravenous administration of magnesium sulfate on corrected serum calcium level and nephrogenous cyclic AMP excretion in normal human subjects

S. Tarui, N. Kono, K. Nonaka, 1986, Calcified Tissue International.

The inhibitory effect of noradrenaline on thyrotrophin-stimulated 3,5,3'-tri-iodothyronine and thyroxine release is mediated through a Ca(2+)-dependent process in the thyroid gland of the mouse.

Y. Matsuzawa, T. Hanafusa, N. Kono, 1993, The Journal of endocrinology.

Familial renal hypouricemia with intact reabsorption of uric acid.

S. Tarui, N. Kono, H. Nakajima, 1987, Nephron.

Examination of islets in the pancreas biopsy specimens from newly diagnosed Type 1 (insulin-dependent) diabetic patients

K. Yamagata, T. Hanafusa, S. Kawata, 1990, Diabetologia.

Retroperitoneal cellular schwannoma: report of a case diagnosed by the presence of S-100 protein.

T. Hanafusa, K. Tokunaga, N. Kono, 1991, Japanese Journal of Medicine.

Animal model of systemic carnitine deficiency: analysis in C3H-H-2 degrees strain of mouse associated with juvenile visceral steatosis.

T. Saheki, S. Kawata, T. Koizumi, 1991, Biochemical and biophysical research communications.

Chicken Liver Phosphofructokinase

K. Uyeda, N. Kono, 1974 .

The association of serum testosterone levels and ventricular repolarization

H. Völzke, J. Witteman, B. Stricker, 2009, European Journal of Epidemiology.

Lipopolysaccharide augments HLA-A,B,C molecule expression but inhibits interferon-gamma-induced HLA-DR molecule expression on cultured human endothelial cells.

T. Hanafusa, S. Tarui, N. Kono, 1991, Immunology.

Increased plasma uric acid after exercise in muscle phosphofructokinase deficiency

I. Mineo, S. Tarui, N. Kono, 1986, Neurology.

Genetic defect in muscle phosphofructokinase deficiency. Abnormal splicing of the muscle phosphofructokinase gene due to a point mutation at the 5'-splice site.

T. Tanaka, T. Noguchi, K. Hotta, 1990, The Journal of biological chemistry.

Transcatheter arterial chemo-embolization for humoral hypercalcemia of hepatocellular carcinoma

H. Kiyokawa, A. Ono, I. Mineo, 1988, Gastroenterologia Japonica.

Preventive effect of a new immunosuppressant FK-506 on insulitis and diabetes in non-obese diabetic mice

K. Yamagata, T. Hanafusa, S. Tarui, 1990, Diabetologia.

Erythrocyte Glycolysis and Its Marked Alteration by Muscular Exercise in Type

Takao Shimizu, H. Kiyokawa, I. Mineo, 2005 .

Exercise induced alteration of erythrocyte glycolysis associated with myogenic hyperuricemia.

H. Kiyokawa, I. Mineo, N. Kono, 1989, Advances in experimental medicine and biology.

Kinetic properties of erythrocyte phosphofructokinase in patients with type VII glycogenosis from two families — close similarity to liver type phosphofructokinase

I. Mineo, N. Kono, K. Nonaka, 1984, Journal of Inherited Metabolic Disease.

Type VII glycogenosis (muscle and erythrocyte phosphofructokinase deficiency).

S. Tarui, N. Kono, M. Kuwajima, 1978, Monographs in human genetics.

Hyperuricemia in type V glycogenosis

I. Mineo, S. Tarui, N. Kono, 1987, Neurology.

Myogenic hyperuricemia: a comparative study between type V and type VII glycogenosis.

H. Kiyokawa, I. Mineo, N. Kono, 1989, Advances in experimental medicine and biology.

Myogenic hyperuricemia in hypoparathyroidism.

I. Mineo, N. Kono, M. Kuwajima, 1991, Advances in experimental medicine and biology.

Purine degradation in contracting fast and slow muscles of rats.

H. Kiyokawa, I. Mineo, N. Kono, 1989, Advances in experimental medicine and biology.

The effect of hypermagnesaemia on serum immunoreactive calcitonin levels in normal human subjects.

S. Tarui, N. Kono, T. Onishi, 1987, Acta Endocrinologica.

Demonstration of Interleukin-β on Perifollicular Endothelial Cells in the Thyroid Glands of Patients with Graves’ Disease*

T. Hanafusa, K. Yoshizaki, S. Tarui, 1989 .

Novel missense mutation (W686C) of the phosphofructokinase‐M gene in a Japanese patient with a mild form of glycogenosis VII

Y. Matsuzawa, T. Noguchi, S. Tarui, 1996 .

Insulin and epidermal growth factor stimulate glycolysis in quiescent 3T3 fibroblasts with no changes in key glycolytic enzyme activities.

S. Tarui, N. Kono, K. Nonaka, 1984, Endocrinologia japonica.

[The pathogenesis of non-insulin dependent diabetes mellitus].

H. Kiyokawa, S. Tarui, N. Kono, 1990, Nihon rinsho. Japanese journal of clinical medicine.

Function of DR-positive thyrocytes from patients with Graves' disease: quantitative analysis of thyroid peroxidase content by fluorescent photometry.

T. Hanafusa, S. Tarui, N. Kono, 1992, The Journal of clinical endocrinology and metabolism.

Interferon-gamma inhibits thyroid-stimulating hormone-induced morphological changes and induces the expression of major histocompatibility complex class II antigen in thyroid follicles in suspension culture.

T. Hanafusa, S. Tarui, N. Kono, 1991, Endocrinology.

[Carnitine].

N. Kono, M. Cairella, 1961, La Clinica terapeutica.

Renal hypouricaemia in a patient with 48,XXYY syndrome.

S. Tarui, N. Kono, H. Nakajima, 1986, Postgraduate medical journal.

Asymptomatic hereditary xanthinuria: a case report.

N. Kono, E. Murakami, K. Hiwada, 1990, Japanese journal of medicine.

Basal and Calcium-stimulated Serum Calcitonin Levels in Chronic Hypergiucocorticoid Subjects

S. Tarui, N. Kono, Yusaku Nakamura, 1987 .

Cell-to-cell communication in cultured rat thyroid monolayer cells is inhibited dose-dependently by methimazole.

H. Yamasaki, T. Hanafusa, S. Tarui, 1992, Research communications in chemical pathology and pharmacology.

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients.

K. Yamagata, A. Imagawa, T. Hanafusa, 1993, The Journal of clinical investigation.

Decreased renal clearance of xanthine and hypoxanthine in a patient with renal hypouricemia: a new defect in renal handling of purines.

H. Kiyokawa, I. Mineo, N. Kono, 1992, Nephron.

Decreased xanthine oxidase activities and increased urinary oxypurines in heterozygotes for hereditary xanthinuria.

I. Mineo, S. Tarui, N. Kono, 1990, Clinica chimica acta; international journal of clinical chemistry.

A genetic defect in muscle phosphofructokinase deficiency, a typical clinical entity presenting myogenic hyperuricemia.

T. Noguchi, K. Hotta, I. Mineo, 1991, Advances in experimental medicine and biology.

Improvement of hemolysis in muscle phosphofructokinase deficiency by restriction of exercise.

N. Kono, M. Kuwajima, H. Toyoda, 1996, Internal medicine.

The Exercise Test

S. Tarui, N. Kono, 1990 .

Glucose infusion abolishes the excessive ATP degradation in working muscles of a patient with McArdle's disease

H. Kiyokawa, I. Mineo, S. Tarui, 1990, Muscle and Nerve.

Molecular aspect of myogenic hyperuricemia: cloning of human muscle phosphofructokinase cDNA.

T. Noguchi, I. Mineo, S. Tarui, 1988 .

Glycogenosis type V (McArdle's disease) with hyperuricemia. A case report and clinical investigation.

N. Kono, K. Jinnai, F. Kanda, 1993, European neurology.