D. Macmillan

发表

Evolving strategies for enzyme engineering.

F. Arnold, J. Bloom, C. Otey, 2005, Current opinion in structural biology.

Evolving Strategies for Protein Synthesis Converge on Native Chemical Ligation

D. Macmillan, 2007 .

PEPTIDE FRAGMENTS OF A ß-DEFENSIN DERIVATIVE WITH POTENT 1 BACTERICIDAL ACTIVITY 2 3

Martin De Cecco, D. Uhrín, P. Barran, 2010 .

Peptide Fragments of a β-Defensin Derivative with Potent Bactericidal Activity

D. Uhrín, P. Barran, J. Dorin, 2010, Antimicrobial Agents and Chemotherapy.

Elucidating the Function of Complex‐Type Oligosaccharides by Use of Chemical Synthesis of Homogeneous Glycoproteins

D. Macmillan, Y. Kajihara, M. Izumi, 2011 .

Mucin-Based Vaccines

J. Richardson, D. Macmillan, 2008 .

Access to phosphoproteins and glycoproteins through semi-synthesis, Native Chemical Ligation and N→S acyl transfer.

S. Smerdon, J. Masania, D. Macmillan, 2010, Organic & biomolecular chemistry.

Native N-glycopeptide thioester synthesis through N→S acyl transfer

D. Macmillan, B. Premdjee, A. Adams, 2011, Bioorganic & medicinal chemistry letters.

Exploring neoglycoprotein assembly through native chemical ligation using neoglycopeptide thioesters prepared via N-->S acyl transfer.

J. Richardson, D. Macmillan, J. Blanc, 2010, Organic & biomolecular chemistry.

Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3*

D. Uhrín, P. Barran, J. Dorin, 2008, Journal of Biological Chemistry.

Peptide Fragments of a (cid:1) -Defensin Derivative with Potent Bactericidal Activity (cid:1)

Martin De Cecco, D. Uhrín, P. Barran, 2010 .

Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases

V. Kinsler, D. Macmillan, W. Di, 2016, PloS one.

Cyanogen bromide cleavage generates fragments suitable for expressed protein and glycoprotein ligation.

D. Macmillan, Lubna Arham, 2004, Journal of the American Chemical Society.

Expanding the scope of N → S acyl transfer in native peptide sequences.

D. Macmillan, W. Di, B. Cowper, 2015, Organic & biomolecular chemistry.

Evolving strategies for protein synthesis converge on native chemical ligation.

D. Macmillan, 2006, Angewandte Chemie.

Solid-phase synthesis of thioether-linked glycopeptide mimics for application to glycoprotein semisynthesis.

M. Bayrhuber, S. Flitsch, D. Macmillan, 2002, Organic letters.

Persistent kallikrein 5 activation induces atopic dermatitis‐like skin architecture independent of PAR2 activity

E. Healy, D. Macmillan, W. Di, 2017, The Journal of allergy and clinical immunology.

Persistent kallikrein5 activation induces atopic dermatitis-like skin

E. Healy, D. Macmillan, W. Di, 2017 .

Chemoenzymatic synthesis of GDP-azidodeoxymannoses: non-radioactive probes for mannosyltransferase activity.

S. Marchesan, D. Macmillan, 2008, Chemical communications.

Sunflower trypsin inhibitor (SFTI-1) analogues of synthetic and biological origin via N→S acyl transfer: potential inhibitors of human Kallikrein-5 (KLK5)

D. Macmillan, W. Di, Y. Zhu, 2014 .

Peptide and protein thioester synthesis via N-->S acyl transfer.

D. Macmillan, Jaskiranjit Kang, 2010, Organic & biomolecular chemistry.

The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus

Derek Macmillan, Tian Man, Hongwei Wang, 2013, PloS one.

Towards biomolecular assembly employing extended native chemical ligation in combination with thioester synthesis using an N-->S acyl shift.

David W. Anderson, D. Macmillan, Tom Ackrill, 2010, Biopolymers.

Investigation of peptide thioester formation via N→Se acyl transfer

D. Macmillan, A. Adams, 2013, Journal of peptide science : an official publication of the European Peptide Society.

Rapid access to Asp/Glu sidechain hydrazides as thioester precursors for peptide cyclization and glycosylation.

D. Macmillan, N. Barnes, Kudakwashe Nyandoro, 2021, Chemical communications.

Investigation of Cysteine as an Activator of Side-Chain N→S Acyl Transfer and Tail-to-Side-Chain Cyclization

D. Macmillan, Durbis J. Castillo-Pazos, 2017 .

Development of an ion mobility quadrupole time of flight mass spectrometer.

P. Barran, J. Dorin, P. Kemper, 2008, Analytical chemistry.

Design and synthesis of a homogeneous erythropoietin analogue with two human complex-type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods.

D. Macmillan, K. Tezuka, Y. Kajihara, 2009, Angewandte Chemie.

Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides.

R. Field, D. Macmillan, K. P. Ravindranathan Kartha, 2008, Carbohydrate research.

Peptide thioester synthesis through N-->S acyl-transfer: application to the synthesis of a beta-defensin.

J. Dorin, D. Macmillan, Christine Tyrrell, 2009, Organic & biomolecular chemistry.

3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

J. Richardson, D. Macmillan, Jaskiranjit Kang, 2008, Chemical communications.

Microwave-assisted synthesis of cyclopentadienone iron tricarbonyl complexes: molecular structures of [{η4-C4R2C(O)C4H8}Fe(CO)3] (R = Ph, 2,4-F2C6H3, 4-MeOC6H4) and attempts to prepare Fe(II) hydroxycyclopentadienyl–hydride complexes

C. Richard, G. Hogarth, D. Macmillan, 2018, Transition Metal Chemistry.

The synthesis of novel homogeneous glycoproteins

Derek Macmillan, D. Macmillan, 1999 .

Shifting Native Chemical Ligation into Reverse through N→S Acyl Transfer

D. Macmillan, B. Premdjee, A. Adams, 2011, Israel journal of chemistry.

Examination of mercaptobenzyl sulfonates as catalysts for native chemical ligation: application to the assembly of a glycosylated Glucagon-Like Peptide 1 (GLP-1) analogue.

D. Macmillan, B. Cowper, B. Premdjee, 2015, Chemical communications.

Going Round in Circles with N→S Acyl Transfer

D. Macmillan, 2017, Synlett.

Synthesis of Cyclic Peptides through an Intramolecular Amide Bond Rearrangement

P. Barran, J. Dorin, D. Macmillan, 2011, Chembiochem : a European journal of chemical biology.

Rapid synthesis of acyl transfer auxiliaries for cysteine-free native glycopeptide ligation.

David W. Anderson, D. Macmillan, 2004, Organic letters.

Chk2 Oligomerization Studied by Phosphopeptide Ligation

I. Taylor, S. Howell, S. Smerdon, 2008, Journal of Biological Chemistry.

Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives.

G. Waksman, D. Macmillan, S. Virdee, 2010, Chemistry & biology.

M. Rolfe, P. Barran, S. Howie, 2009, European journal of immunology.

The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator

S. Smerdon, D. H. Larsen, J. Lukas, 2012, Nucleic acids research.

Small-molecule inhibition of c-MYC:MAX leucine zipper formation is revealed by ion mobility mass spectrometry.

Giovanna Zinzalla, Massimiliano Porrini, Derek MacMillan, 2012, Journal of the American Chemical Society.

Semi-synthesis of glycoproteins from E. coli through native chemical ligation.

J. Richardson, D. Macmillan, 2011, Methods in molecular biology.

Recent developments in the synthesis and discovery of oligosaccharides and glycoconjugates for the treatment of disease.

D. Macmillan, A. Daines, 2003, Current medicinal chemistry.

2,3,4‐Trimethoxy‐6‐[[(4‐methoxyphenyl)‐methyl]thio]benzaldehyde

D. Macmillan, 2009 .

Optimisation of chemical protein cleavage for erythropoietin semi-synthesis using native chemical ligation

J. Richardson, D. Macmillan, Jonathan P. Richardson, 2008, Organic & biomolecular chemistry.

Selective in vitro glycosylation of recombinant proteins: semi-synthesis of novel homogeneous glycoforms of human erythropoietin.

D Macmillan, R. Bill, S. Flitsch, 2001, Chemistry & biology.

Isoleucine/leucine2 is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6.

P. Barran, J. Dorin, D. Campopiano, 2010, Molecular immunology.

New directions in glycoprotein engineering

C. Bertozzi, D. Macmillan, 2000 .

Modular assembly of glycoproteins: towards the synthesis of GlyCAM-1 by using expressed protein ligation.

Derek Macmillan, Carolyn R Bertozzi, C. Bertozzi, 2004, Angewandte Chemie.

Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements.

P. Barran, J. Dorin, D. Campopiano, 2010, Physical chemistry chemical physics : PCCP.

Semisynthesis of Erythropoietin Analog Having Three Oligosaccharides

D. Macmillan, K. Tezuka, Y. Kajihara, 2011 .

Expanding the scope of N → S acyl transfer in native peptide sequences.

D. Macmillan, W. Di, B. Cowper, 2015, Organic & biomolecular chemistry.

Computer Aided Production Engineering (CAPE) 2007

J. A. McGeough, Akira Okada, Brian Flynn, 2007 .

56th CIRP General Assembly

J. A. McGeough, Akira Okada, Brian Flynn, 2006 .

CIRP Annuals 2007 - Manufacturing Technology

J. A. McGeough, Akira Okada, Brian Flynn, 2007 .

Peptide thioester synthesis through N-->S acyl-transfer: application to the synthesis of a beta-defensin.

J. Dorin, D. Macmillan, Christine Tyrrell, 2009, Organic & biomolecular chemistry.

A novel neoglycopeptide linkage compatible with native chemical ligation.

D. Macmillan, J. Blanc, 2006, Organic & biomolecular chemistry.

Conformational preferences of linear beta-defensins are revealed by ion mobility-mass spectrometry.

P. Barran, J. Dorin, D. Campopiano, 2010, The journal of physical chemistry. B.

Making Ends Meet: Chemically Mediated Circularization of Recombinant Proteins

D. Craik, D. Macmillan, B. Cowper, 2013, Chembiochem : a European journal of chemical biology.