Lu Shen

发表

The cost of Alzheimer's disease in China and re-estimation of costs worldwide

J Zhang, L. Tan, Q. Guo, 2018, Alzheimer's & Dementia.

Mutation analysis of the TIA1 gene in Chinese patients with amyotrophic lateral sclerosis and frontotemporal dementia

B. Tang, Li-li Hou, Xinxiang Yan, 2017, Neurobiology of Aging.

Mutation analysis of the ATM gene in two Chinese patients with ataxia telangiectasia

K. Xia, Q. Pan, H. Dai, 2006, Journal of the Neurological Sciences.

Disruption of Regional Brain Activity and Functional Connectivity in Patients with Asymptomatic Vulnerable Carotid Plaque

Wei He, W. Liao, Lu Shen, 2019, Neuroscience Letters.

Spinocerebellar ataxia type 35 (SCA35)-associated transglutaminase 6 mutants sensitize cells to apoptosis.

K. Xia, B. Tang, Ji-feng Guo, 2013, Biochemical and biophysical research communications.

SUMO-1 Modification on K166 of PolyQ-Expanded aTaxin-3 Strengthens Its Stability and Increases Its Cytotoxicity

K. Xia, B. Tang, Juan Du, 2013, PloS one.

Biallelic Intronic AAGGG Expansion of RFC1 is Related to Multiple System Atrophy

T. Ashizawa, K. Xia, B. Tang, 2020, Annals of neurology.

Identification of RELN variation p.Thr3192Ser in a Chinese family with schizophrenia

Zhening Liu, Haihong Liu, Jingping Zhao, 2016, Scientific Reports.

SPG46 and SPG56 are rare causes of hereditary spastic paraplegia in China

B. Tang, Juan Du, Lu Shen, 2016, Journal of Neurology.

Analyses Mutations in GSN, CST3, TTR, and ITM2B Genes in Chinese Patients With Alzheimer’s Disease

Lu Shen, Bin Jiao, Xixi Liu, 2020, Frontiers in Aging Neuroscience.

Mutational analysis of PRNP in Alzheimer’s disease and frontotemporal dementia in China

Lu Shen, B. Tang, Lu Shen, 2016, Scientific Reports.

Genetics of frontotemporal dementia in China

Lu Shen, Bin Jiao, Yaling Jiang, 2021, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Mutational analysis in early-onset familial Alzheimer's disease in Mainland China

B. Tang, Xinxiang Yan, Yanjiang Wang, 2014, Neurobiology of Aging.

Analyses MAPT, GRN, and C9orf72 mutations in Chinese patients with frontotemporal dementia

B. Tang, Xinxiang Yan, Lu Shen, 2016, Neurobiology of Aging.

Rare NRXN1 missense variants identified in autism interfered protein degradation and Drosophila sleeping.

K. Xia, L. Xia, Lu Shen, 2021, Journal of psychiatric research.

Identification of Alzheimer's disease-associated rare coding variants in the ECE2 gene.

K. Xia, Jinchen Li, B. Tang, 2020, JCI Insight.

Association of Genes Involved in the Metabolic Pathways of Amyloid-β and Tau Proteins With Sporadic Late-Onset Alzheimer’s Disease in the Southern Han Chinese Population

B. Tang, Xinxiang Yan, Lu Shen, 2020, Frontiers in Aging Neuroscience.

Ethnicity-specific and overlapping alterations of brain hydroxymethylome in Alzheimer's disease.

Xiongwei Zhu, P. Jin, Hao Wu, 2019, Human molecular genetics.

New ZNF644 mutations identified in patients with high myopia

K. Xia, L. Xia, Hui Guo, 2014, Molecular vision.

A diagnostic gene chip for hereditary spastic paraplegias

K. Xia, Zhengmao Hu, B. Tang, 2013, Brain Research Bulletin.

GCH1 variants contribute to the risk and earlier age-at-onset of Parkinson’s disease: a two-cohort case-control study

B. Tang, Zhenghuan Fang, Ji-feng Guo, 2020, Translational Neurodegeneration.

Evaluation of Peripheral Immune Activation in Amyotrophic Lateral Sclerosis

K. Xia, B. Tang, Ji-feng Guo, 2020, Frontiers in Neurology.

Spin labeling artery method perfusion MRI study of SPG4 and SCA3/MJD.

W. Liao, Lu Shen, Xiao-yi Wang, 2014, Magnetic resonance imaging.

A Systematic Review and Meta-Analysis of Deep Brain Stimulation for Progressive Supranuclear Palsy

Lu Shen, Bin Jiao, Yafang Zhou, 2020 .

Genetic Identification Is Critical for the Diagnosis of Parkinsonism: A Chinese Pedigree with Early Onset of Parkinsonism

K. Xia, B. Tang, Ji-feng Guo, 2015, PloS one.

Expansion of GGC repeat in the human-specific NOTCH2NLC gene is associated with essential tremor.

K. Xia, B. Tang, Fan Liang, 2019, Brain : a journal of neurology.

UBA5 Mutations Cause a New Form of Autosomal Recessive Cerebellar Ataxia

B. Tang, Ji-feng Guo, Guanghui Wang, 2016, PLoS ONE.

Profiling the Genome-Wide Landscape of Short Tandem Repeats by Long-Read Sequencing

K. Xia, Fan Liang, Guihu Zhao, 2022, Frontiers in Genetics.

Direct Interaction Between Two Parkinson-related Protein Parkin and PINK1*: Direct Interaction Between Two Parkinson-related Protein Parkin and PINK1*

B. Tang, Ji-feng Guo, Hong Jiang, 2010 .

The BAG2 Protein Stabilises PINK1 By Decreasing its Ubiquitination.

B. Tang, Ji-feng Guo, Guanghui Wang, 2013, Biochemical and biophysical research communications.

Genetic and clinical analyses of spinocerebellar ataxia type 8 in mainland China

K. Xia, B. Tang, Hong Jiang, 2019, Journal of Neurology.

Spinocerebellar ataxia type 23 is an uncommon SCA subtype in the Chinese Han population

K. Xia, B. Tang, Hong Jiang, 2012, Neuroscience Letters.

Spinocerebellar ataxia type 11 in the Chinese Han population

K. Xia, Q. Pan, B. Tang, 2010, Neurological Sciences.

Lack of variation of ATTCT pentanucleotide repeats at ATXN10 gene between clinically diagnosed ataxia patients and normal individuals originated from Chinese Han

K. Xia, Q. Pan, B. Tang, 2008, Journal of Genetics.

Spinocerebellar ataxia type 6 in Mainland China: Molecular and clinical features in four families

Q. Pan, B. Tang, Hong Jiang, 2005, Journal of the Neurological Sciences.

Spinocerebellar ataxia type 21 exists in the Chinese Han population

K. Xia, Q. Pan, B. Tang, 2016, Scientific reports.

Three novel mutations of the spastin gene in Chinese patients with hereditary spastic paraplegia.

K. Xia, Q. Pan, H. Dai, 2004, Archives of neurology.

Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson’s disease in Chinese Han population

K. Xia, B. Tang, Ji-feng Guo, 2013, BMC Neurology.

The progression rate of spinocerebellar ataxia type 3 varies with disease stage

K. Xia, B. Tang, Hong Jiang, 2022, Journal of translational medicine.

A neuropathological study at autopsy of early onset spinocerebellar ataxia 6

B. Tang, Hong Jiang, Lu Shen, 2010, Journal of Clinical Neuroscience.

Novel ATL1 mutation in a Chinese family with hereditary spastic paraplegia: A case report and review of literature

Lu Shen, Zhang-Yuan Lin, Zhenhua Yuan, 2019, World journal of clinical cases.

Targeted sequencing on neurodegenerative genes identified novel causal and risk variants of familial Alzheimer's disease

B. Tang, Xinxiang Yan, Lu Shen, 2020 .

C9orf72 hexanucleotide expansion analysis in Chinese patients with multiple system atrophy.

K. Xia, B. Tang, Hong Jiang, 2015, Parkinsonism & related disorders.

The Natural History of Spinocerebellar Ataxia Type 3 in Mainland China: A 2-Year Cohort Study

T. Klockgether, K. Xia, B. Tang, 2022, Frontiers in Aging Neuroscience.

PSAP variants in Parkinson's disease: a large cohort study in Chinese mainland population.

B. Tang, Guihu Zhao, Zhenghuan Fang, 2020, Brain : a journal of neurology.

The role of genetics in Parkinson's disease: a large cohort study in Chinese mainland population.

H. Shang, Z. Wang, P. Chan, 2020, Brain : a journal of neurology.

Rare TBK1 variants in patients with frontotemporal dementia and amyotrophic lateral sclerosis in a Chinese cohort

B. Tang, Xinxiang Yan, Lu Shen, 2018, Translational Neurodegeneration.

FTD-PSP is an Unusual Clinical Phenotype in A Frontotemporal Dementia Patient with A Novel Progranulin Mutation

Lu Shen, Y. Luo, Kunling Jin, 2021, Aging and disease.

Analysis of SCA2 and SCA3/MJD repeats in Parkinson's disease in mainland China: Genetic, clinical, and positron emission tomography findings

K. Xia, Q. Pan, B. Tang, 2009, Movement disorders : official journal of the Movement Disorder Society.

Six cases of SCA3/MJD patients that mimic hereditary spastic paraplegia in clinic

K. Xia, Q. Pan, B. Tang, 2009, Journal of the Neurological Sciences.

Analysis of PLA2G6 gene mutation in sporadic early-onset parkinsonism patients from Chinese population

B. Tang, Ji-feng Guo, Xinxiang Yan, 2012, Neuroscience Letters.

New Model for Estimation of the Age at Onset in Spinocerebellar Ataxia Type 3

T. Klockgether, K. Xia, Jinchen Li, 2021, Neurology.

Mutation screening of the PRRT2 gene for benign epilepsy with centrotemporal spikes in Chinese mainland population

K. Xia, B. Tang, Hong Jiang, 2017, The International journal of neuroscience.

Direct Conversion of Norm al and Alzheimer ’ s Disease Human Fibroblasts into Neuronal Cells by Small Molecules Graphical

B. Tang, Gangcai Xie, Hanzhi T. Zhao, 2022 .

Variants in the Niemann-pick type C genes are not associated with Alzheimer's disease: a large case-control study in the Chinese population

Jinchen Li, Lu Shen, Bin Jiao, 2022, Neurobiology of Aging.

Clinical findings of autosomal-dominant striatal degeneration and PDE8B mutation screening in parkinsonism and related disorders.

B. Tang, Xiaoping Yi, Hong Jiang, 2019, Parkinsonism & related disorders.

A Spinocerebellar Ataxia Family with Expanded Alleles in the Tata-Binding Protein Gene and Ataxin-3 Gene

B. Tang, Hong Jiang, Lu Shen, 2010, The International journal of neuroscience.

Mutation analysis of the small heat shock protein 27 gene in chinese patients with Charcot-Marie-Tooth disease.

K. Xia, Q. Pan, Biao Chen, 2005, Archives of neurology.

Identification of GGC repeat expansion in the NOTCH2NLC gene in amyotrophic lateral sclerosis

B. Tang, Hong Jiang, Lu Shen, 2020, Neurology.

Mutation and Clinical Characteristics of Autosomal-Dominant Hereditary Spastic Paraplegias in China

K. Xia, Q. Pan, B. Tang, 2014, Neurodegenerative Diseases.

Mutation analysis of GLT8D1 and ARPP21 genes in amyotrophic lateral sclerosis patients from mainland China

Jinchen Li, B. Tang, Lu Shen, 2020, Neurobiology of Aging.

Novel mutations of the SPG11 gene in hereditary spastic paraplegia with thin corpus callosum

K. Xia, B. Tang, N. Li, 2008, Journal of the Neurological Sciences.

A novel mutation of KCNQ3 gene in a Chinese family with benign familial neonatal convulsions

K. Xia, Q. Pan, B. Tang, 2003, Epilepsy Research.

Rare GCH1 heterozygous variants contributing to Parkinson's disease.

K. Xia, B. Tang, Ji-feng Guo, 2017, Brain : a journal of neurology.

Mutations of CCNF gene is rare in patients with amyotrophic lateral sclerosis and frontotemporal dementia from Mainland China

B. Tang, Li-li Hou, Lu Shen, 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.

Identification of C9orf72 repeat expansions in patients with amyotrophic lateral sclerosis and frontotemporal dementia in mainland China

K. Xia, B. Tang, Xinxiang Yan, 2014, Neurobiology of Aging.

Screening of SOD1, FUS and TARDBP genes in patients with amyotrophic lateral sclerosis in central-southern China

B. Tang, Li-li Hou, Xinxiang Yan, 2016, Scientific Reports.

Mutation Detection in Candidate Genes for Benign Familial Infantile Seizures on a Novel Locus

K. Xia, Q. Pan, Zhengmao Hu, 2010, The International journal of neuroscience.

C9ORF72 repeat expansion is not detected in sporadic ataxia patients in mainland China

B. Tang, Hong Jiang, Lu Shen, 2016, Journal of the Neurological Sciences.

The Development of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disorders

Lu Shen, Bin Jiao, Qijie Yang, 2020, Frontiers in Genetics.

Multiple reversible encephalitic attacks: a rare manifestation of neuronal intranuclear inclusion disease

Zaiqiang Zhang, Lu Shen, Kai Li, 2020, BMC Neurology.

Detection of changes in synaptic density in amyotrophic lateral sclerosis patients using 18F‐SynVesT‐1 positron emission tomography

Yiyun Huang, M. Zhou, B. Tang, 2022, European journal of neurology.

Familial amyloid polyneuropathy with chronic paroxysmal dry cough in Mainland China: A Chinese family with a proven heterozygous missense mutation c.349G>T in the transthyretin gene

B. Tang, Xinxiang Yan, Lu Shen, 2019, Journal of Clinical Neuroscience.

Adult-onset neuronal intranuclear inclusion disease, with both stroke-like onset and encephalitic attacks: a case report

Lu Shen, Yun Tian, Ying-Qiu Huang, 2021, BMC Neurology.

One PMP22/MPZ and Three MFN2/GDAP1 Concomitant Variants Occurred in a Cohort of 189 Chinese Charcot-Marie-Tooth Families

B. Tang, Ji-feng Guo, Lu Shen, 2022, Frontiers in Neurology.

Genotype and phenotype distribution of 435 patients with Charcot–Marie–Tooth disease from central south China

Zhengmao Hu, B. Tang, S. Zuchner, 2021, European journal of neurology.

Homozygosity mapping and next generation sequencing for the genetic diagnosis of hereditary ataxia and spastic paraplegia in consanguineous families.

Zhengmao Hu, B. Tang, Hong Jiang, 2020, Parkinsonism & related disorders.

Identification of novel SPG11 mutations in a cohort of Chinese families with hereditary spastic paraplegia

B. Tang, Hong Jiang, Lu Shen, 2018, The International journal of neuroscience.

Association of variants in the KIF1A gene with amyotrophic lateral sclerosis

B. Tang, Ji-feng Guo, Zhuohua Zhang, 2022, Translational Neurodegeneration.

Genetic and Clinical Features in 24 Chinese Distal Hereditary Motor Neuropathy Families

Zhengmao Hu, B. Tang, Ji-feng Guo, 2020, Frontiers in Neurology.

[Clinical and mutational analysis of KCNQ3 gene in a Chinese family with benign familial neonatal convulsions].

K. Xia, B. Tang, Ji-feng Guo, 2006, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

Research on Mitochondrial DNA Mutations in Patients with SCA3/MJD

B. Tang, Hong Jiang, Lu Shen, 2017, bioRxiv.

Chinese patients with distal hereditary motor neuropathy: an analysis of clinical characteristics: Chinese patients with distal hereditary motor neuropathy: an analysis of clinical characteristics

B. Tang, Hong Jiang, Xinxiang Yan, 2010 .

Characterization of the central motor conduction time in a large cohort of spinocerebellar ataxia type 3 patients.

K. Xia, B. Tang, Hong Jiang, 2022, Parkinsonism & related disorders.

[Gene screening in five Chinese families with hereditary spastic paraplegia with thin corpus callosum].

K. Xia, B. Tang, Lu Shen, 2007, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

Clinical features of hereditary spastic paraplegia with thin corpus callosum: report of 5 Chinese cases.

B. Tang, W. Luo, Hong Jiang, 2004, Chinese medical journal.

Familial paroxysmal kinesigenic dyskinesia is associated with mutations in the KCNA1 gene

Zhixian Yang, K. Xia, B. Tang, 2018, Human molecular genetics.

Multiple Visual Rating Scales Based on Structural MRI and a Novel Prediction Model Combining Visual Rating Scales and Age Stratification in the Diagnosis of Alzheimer's Disease in the Chinese Population

B. Tang, Mengxing Liu, Xinxiang Yan, 2019, Front. Neurol..

Performance of Plasma Amyloid β, Total Tau, and Neurofilament Light Chain in the Identification of Probable Alzheimer's Disease in South China

B. Tang, Xinxiang Yan, Lu Shen, 2021, Frontiers in Aging Neuroscience.

Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules.

Qinying Wang, Gang Pei, Lu Shen, 2015, Cell stem cell.

TGM6 identified as a novel causative gene of spinocerebellar ataxias using exome sequencing.

Xin Jin, K. Xia, Q. Pan, 2010, Brain : a journal of neurology.

Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias

K. Xia, B. Tang, Zhengmao Hu, 2011, Brain : a journal of neurology.

Novel mutation of EDA causes new asymmetrical X‐linked hypohidrotic ectodermal dysplasia phenotypes in a female

K. Xia, Hui Guo, Zhengmao Hu, 2019, The Journal of dermatology.

Identification of One BOCR Mutation and Five NF1 Mutations in Male Patients with Neurofibromatosis Type 1 and Congenital Pseudarthrosis of the Tibia

Li-li Hou, Lu Shen, Zhang-Yuan Lin, 2016 .

Genome-wide copy number variation analysis in a Chinese autism spectrum disorder cohort

Liangdan Sun, Xuejun Zhang, Jingping Zhao, 2017, Scientific Reports.

A presenilin-1 mutation causes Alzheimer disease without affecting Notch signaling

C. Rankin, B. Tang, Ji-feng Guo, 2018, Molecular Psychiatry.

Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders

P. Jin, K. Xia, B. Tang, 2019, American journal of human genetics.

Associations of risk genes with onset age and plasma biomarkers of Alzheimer’s disease: a large case–control study in mainland China

Jinchen Li, Lu Shen, Zhenhua Yuan, 2022, Neuropsychopharmacology.

Shanghai cognitive intervention of mild cognitive impairment for delaying progress with longitudinal evaluation-a prospective, randomized controlled study (SIMPLE): rationale, design, and methodology

Wei Zhao, H. Yu, Chunbo Li, 2018, BMC Neurology.

Rare inherited missense variants of POGZ associate with autism risk and disrupt neuronal development.

Jingping Zhao, K. Xia, J. Ou, 2019, Journal of genetics and genomics = Yi chuan xue bao.

Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China

B. Tang, Ling Huang, Hong Jiang, 2020, The European journal of neuroscience.

Polygenic Analysis of Late-Onset Alzheimer’s Disease from Mainland China

Mary Miu Yee Waye, Maggie Haitian Wang, Lu Shen, 2015, PloS one.

Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns

Lu Shen, Bin Jiao, Weiwei Zhang, 2016, Stem cells international.

Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

Bradley P. Coe, B. Coe, C. Baker, 2018, Molecular Autism.

Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population

M. Nalls, A. Singleton, C. Blauwendraat, 2023, npj Parkinson's Disease.

Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission

Mahshid S. Azamian, J. Rosenfeld, J. Gécz, 2019, Science Advances.

Expression of expanded GGC repeats within NOTCH2NLC causes behavioral deficits and neurodegeneration in a mouse model of neuronal intranuclear inclusion disease

K. Xia, Yujing Li, B. Tang, 2022, Science advances.

Identification of CHIP as a Novel Causative Gene for Autosomal Recessive Cerebellar Ataxia

Jun Wang, Jianguo Zhang, K. Xia, 2013, PloS one.

The role of genetics in neurodegenerative dementia: a large cohort study in South China

Jinchen Li, B. Tang, Xinxiang Yan, 2021, NPJ genomic medicine.

DNA Methylation as a Biomarker for Neuropsychiatric Diseases

B. Tang, Ji-feng Guo, Lu Shen, 2012, The International journal of neuroscience.

Prediction of orthostatic hypotension in multiple system atrophy and Parkinson disease

K. Xia, B. Tang, Ji-feng Guo, 2016, Scientific Reports.

The role of NOTCH3 variants in Alzheimer's disease and subcortical vascular dementia in the Chinese population

B. Tang, Lu Shen, Junling Wang, 2021, CNS neuroscience & therapeutics.

SLC39A5 dysfunction impairs extracellular matrix synthesis in high myopia pathogenesis

K. Xia, L. Xia, Hui Guo, 2021, Journal of cellular and molecular medicine.

SLC39A5 mutations interfering with the BMP/TGF-β pathway in non-syndromic high myopia

Liangdan Sun, Xuejun Zhang, K. Xia, 2014, Journal of Medical Genetics.

Excess of RALGAPB de novo variants in neurodevelopmental disorders.

K. Xia, J. Ou, Kuokuo Li, 2020, European journal of medical genetics.

Small heat-shock protein 22 mutated in autosomal dominant Charcot-Marie-Tooth disease type 2L

K. Xia, Q. Pan, H. Dai, 2005, Human Genetics.

LRRK2 A419V variant is a risk factor for Parkinson's disease in Asian population

Yuan Zhang, K. Xia, B. Tang, 2015, Neurobiology of Aging.

Identification of CHCHD2 mutations in patients with Alzheimer's disease, amyotrophic lateral sclerosis and frontotemporal dementia in China.

B. Tang, Li-li Hou, Lu Shen, 2018, Molecular medicine reports.

Light-Up Nonthiolated Aptasensor for Low-Mass, Soluble Amyloid-β40 Oligomers at High Salt Concentrations.

J. Xiang, Chunyan Deng, Chunyang Lei, 2018, Analytical chemistry.

Variant in the 3′ region of SNCA associated with Parkinson’s disease and serum α-synuclein levels

B. Tang, Ji-feng Guo, Xinxiang Yan, 2012, Journal of Neurology.

Coding mutations in NUS1 contribute to Parkinson’s disease

H. Shang, P. Chan, K. Xia, 2018, Proceedings of the National Academy of Sciences.

A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia

Li-Jun Jiang, M. Cantillon, Wei Chen, 2021, Alzheimer's research & therapy.

A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia

Li-Jun Jiang, M. Cantillon, Wei Chen, 2020, Alzheimer's Research & Therapy.

Exome sequencing released a case of X-linked adrenoleukodystrophy mimicking recessive hereditary spastic paraplegia.

K. Xia, B. Tang, Xinxiang Yan, 2013, European journal of medical genetics.

A new locus for autosomal dominant Charcot-Marie-Tooth disease type 2 (CMT2L) maps to chromosome 12q24

K. Xia, Q. Pan, H. Dai, 2004, Human Genetics.

Mutation analysis of Parkin, PINK1, DJ‐1 and ATP13A2 genes in Chinese patients with autosomal recessive early‐onset Parkinsonism

K. Xia, Q. Pan, B. Tang, 2008, Movement disorders : official journal of the Movement Disorder Society.

Spinocerebellar ataxias in mainland China: an updated genetic analysis among a large cohort of familial and sporadic cases.

K. Xia, Q. Pan, B. Tang, 2011, Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.

Identification of CHCHD10 Mutation in Chinese Patients with Alzheimer Disease

B. Tang, Lu Shen, Bin Jiao, 2016, Molecular Neurobiology.

High prevalence of CHCHD10 mutation in patients with frontotemporal dementia from China.

B. Tang, Li-li Hou, Lu Shen, 2016, Brain : a journal of neurology.

Analysis of Salivary Microbiome in Patients with Alzheimer's Disease.

B. Tang, Lu Shen, Zhenhua Yuan, 2019, Journal of Alzheimer's disease : JAD.

Using next-generation sequencing as a genetic diagnostic tool in rare autosomal recessive neurologic Mendelian disorders

T. Ashizawa, K. Xia, Q. Pan, 2013, Neurobiology of Aging.

DHCR7 rs12785878 T>C Polymorphism Is Associated With an Increased Risk of Early Onset of Alzheimer's Disease in Chinese Population

Lu Shen, Zhang-Yuan Lin, Bin Jiao, 2021, Frontiers in Genetics.

MicroRNA profiling in the serums of SCA3/MJD patients

K. Xia, B. Tang, Hong Jiang, 2014, The International journal of neuroscience.

Identification of expanded repeats in NOTCH2NLC in neurodegenerative dementias

B. Tang, Lu Shen, Junling Wang, 2020, Neurobiology of Aging.

Spinocerebellar ataxia type 6: Systematic patho‐anatomical study reveals different phylogenetically defined regions of the cerebellum and neural pathways undergo different evolutions of the degenerative process

B. Tang, Hong Jiang, Lu Shen, 2010, Neuropathology : official journal of the Japanese Society of Neuropathology.

Distribution of Transglutaminase 6 in the Central Nervous System of Adult Mice

Yu-Qiang Ding, K. Xia, B. Tang, 2013, Anatomical record.

Biallelic loss-of-function variants in NEMF cause central nervous system impairment and axonal polyneuropathy

K. Xia, B. Peterlin, R. Maroofian, 2020, Human Genetics.

Microstructural Alterations in Asymptomatic and Symptomatic Patients with Spinocerebellar Ataxia Type 3: A Tract-Based Spatial Statistics Study

Z. Wang, Z. Qiu, B. Tang, 2017, Front. Neurol..

The Epigenetics of Alzheimer’s Disease: Factors and Therapeutic Implications

Lu Shen, Bin Jiao, Xiaolei Liu, 2018, Front. Genet..

Hypomethylation of SNCA in blood of patients with sporadic Parkinson's disease

B. Tang, Ji-feng Guo, Xinxiang Yan, 2014, Journal of the Neurological Sciences.

Genetics of Progressive Supranuclear Palsy: A Review

Lu Shen, Bin Jiao, Yafang Zhou, 2020, Journal of Parkinson's disease.

Prediction of the Age at Onset of Spinocerebellar Ataxia Type 3 with Machine Learning

Zuping Zhang, K. Xia, Jinchen Li, 2020, Movement disorders : official journal of the Movement Disorder Society.

Screening for two SNPs of LINGO1 gene in patients with essential tremor or sporadic Parkinson's disease in Chinese population

K. Xia, Q. Pan, B. Tang, 2010, Neuroscience Letters.

Resting state fMRI studies in SPG4-linked hereditary spastic paraplegia

B. Tang, Lu Shen, Weihua Liao, 2018, Journal of the Neurological Sciences.

The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease

Wenzhang Wang, Hyoung-Gon Lee, Xiongwei Zhu, 2019, Brain pathology.

Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

H. Cai, Y. Chu, B. Tang, 2017, Front. Neuroanat..

Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland China

B. Tang, Ji-feng Guo, Li-li Hou, 2014, Neurobiology of Aging.

C9orf72 mutation is rare in Alzheimer's disease, Parkinson's disease, and essential tremor in China

K. Xia, B. Tang, Ji-feng Guo, 2013, Front. Cell. Neurosci..

The APOE ε2 allele may decrease the age at onset in patients with spinocerebellar ataxia type 3 or Machado-Joseph disease from the Chinese Han population

K. Xia, B. Tang, Hong Jiang, 2014, Neurobiology of Aging.

Gene4MND: An Integrative Genetic Database and Analytic Platform for Motor Neuron Disease

Guihu Zhao, Jinchen Li, B. Tang, 2021, Frontiers in Molecular Neuroscience.

Demographic and clinical characteristics related to cognitive decline in Alzheimer disease in China

Meng Wang, Nan Zhang, Yu Wang, 2016, Medicine.

Identification of rare RTN3 variants in Alzheimer’s disease in Han Chinese

K. Xia, B. Tang, R. Yan, 2018, Human Genetics.

Association of rare variants in neurodegenerative genes with familial Alzheimer’s disease

B. Tang, Xinxiang Yan, Lu Shen, 2020, Annals of clinical and translational neurology.

Mutation analysis of PRRT2 in two Chinese BFIS families and nomenclature of PRRT2 related paroxysmal diseases

K. Xia, B. Tang, Zhengmao Hu, 2013, Neuroscience Letters.

Mutation spectrum of amyotrophic lateral sclerosis in Central South China

B. Tang, Ling Huang, Hong Jiang, 2021, Neurobiology of Aging.

Receptor expression-enhancing protein 1 gene (SPG31) mutations are rare in Chinese Han patients with hereditary spastic paraplegia.

K. Xia, B. Tang, Hong Jiang, 2009, Chinese medical journal.

Expansion of the phenotypic spectrum of SPG6 caused by mutation in NIPA1

K. Xia, B. Tang, Hong Jiang, 2011, Clinical Neurology and Neurosurgery.

Mutation analysis of CAPN1 in Chinese populations with spastic paraplegia and related neurodegenerative diseases

B. Tang, Zhengmao Hu, Hong Jiang, 2020, Journal of the Neurological Sciences.

The APOE ε4 exerts differential effects on familial and other subtypes of Alzheimer's disease

J. Jia, Ai-hong Zhou, L. Jia, 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

A Novel Potentially Pathogenic Rare Variant in the DNAJC7 Gene Identified in Amyotrophic Lateral Sclerosis Patients From Mainland China

B. Tang, Ling Huang, Hong Jiang, 2020, Frontiers in Genetics.

[Molecular mechanism of idiopathic basal ganglia calcification].

M. Zhang, B. Tang, Lu Shen, 2015, Yi chuan = Hereditas.

Analysis of the GGGGCC Repeat Expansions of the C9orf72 Gene in SCA3/MJD Patients from China

T. Ashizawa, K. Xia, B. Tang, 2015, PloS one.

C9orf72 hexanucleotide repeat expansion analysis in Chinese spastic paraplegia patients

K. Xia, B. Tang, Xinxiang Yan, 2014, Journal of the Neurological Sciences.

Identification of TYW3/CRYZ and FGD4 as susceptibility genes for amyotrophic lateral sclerosis

X. Zuo, Xuejun Zhang, H. Shang, 2019, Neurology: Genetics.

Estrogen receptor-α is localized to neurofibrillary tangles in Alzheimer’s disease

Xiongwei Zhu, B. Tang, S. Siedlak, 2016, Scientific Reports.

Evaluating the Genetic Role of Circadian Clock Genes in Parkinson’s Disease

B. Tang, Xiurong Huang, Ji-feng Guo, 2023, Molecular Neurobiology.

Genetic effect of MTHFR C677T, A1298C, and A1793G polymorphisms on the age at onset, plasma homocysteine, and white matter lesions in Alzheimer's disease in the Chinese population

Lu Shen, Junling Wang, Bin Jiao, 2021, Aging.

Synaptic Loss in Spinocerebellar Ataxia Type 3 Revealed by SV2A Positron Emission Tomography

Yiyun Huang, M. Zhou, T. Ashizawa, 2023, Movement disorders : official journal of the Movement Disorder Society.

[Diffusion weighted imaging of SCA3/MJD and SPG4].

W. Liao, Lu Shen, Xiaoyi Wang, 2014, Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.

Lower serum UA levels in Parkinson's disease patients in the Chinese population

B. Tang, Ji-feng Guo, Xinxiang Yan, 2012, Neuroscience Letters.

A novel SEMA6B variant causes adult-onset progressive myoclonic epilepsy-11 in a Chinese family: A case report and literature review

Ji-feng Guo, Lu Shen, Qian Xu, 2023, Frontiers in Genetics.

The role of exosomes in the pathogenesis of Alzheimer’ disease

Lu Shen, Bin Jiao, Tingting Xiao, 2017, Translational Neurodegeneration.

Downregulation of TOP2 modulates neurodegeneration caused by GGGGCC expanded repeats.

P. Jin, H. Feng, Hao Wu, 2021, Human molecular genetics.

Genetic and clinical analysis of TP73 gene in amyotrophic lateral sclerosis patients from Chinese mainland

B. Tang, Ji-feng Guo, Hong Jiang, 2023, Frontiers in Aging Neuroscience.

Identification of a Novel Mutation in the Presenilin 1 Gene in a Chinese Alzheimer’s Disease Family

Huadong Zhou, X. Yao, Yanjiang Wang, 2014, Neurotoxicity Research.

The BAG2 and BAG5 proteins inhibit the ubiquitination of pathogenic ataxin3-80Q

B. Tang, Ji-feng Guo, Hong Jiang, 2015, The International journal of neuroscience.

Association Between Vitamins and Amyotrophic Lateral Sclerosis: A Center-Based Survey in Mainland China

K. Xia, B. Tang, Hong Jiang, 2020, Frontiers in Neurology.

[Detection of the CAG trinucleotide repeats of MJD1 gene by recombinant DNA technology].

K. Xia, Q. Pan, B. Tang, 2009, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

SCA38 is rare in mainland China

B. Tang, Hong Jiang, Lu Shen, 2015, Journal of the Neurological Sciences.

LRRK2 Pro755Leu variant in ethnic Chinese population with Parkinson's disease

K. Xia, Q. Pan, B. Tang, 2011, Neuroscience Letters.

Coimmunocapture and Electrochemical Quantitation of Total and Phosphorylated Amyloid-β40 Monomers.

J. Xiang, Chunyan Deng, Lu Shen, 2019, Analytical chemistry.

Blood Neurofilament Light Chain in Genetic Ataxia: A Meta‐Analysis

T. Klockgether, T. Ashizawa, K. Xia, 2021, Movement disorders : official journal of the Movement Disorder Society.

[Frequency analysis of autosomal dominant spinocerebellar ataxias in Han population in the Chinese mainland and clinical and molecular characterization of spinocerebellar ataxia type 6].

K. Xia, B. Tang, Hong Jiang, 2005, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

Rare TBK1 variants in patients with frontotemporal dementia and amyotrophic lateral sclerosis in a Chinese cohort

B. Tang, Xinxiang Yan, Lu Shen, 2018, Translational neurodegeneration.

Retinal Microvascular Density Was Associated With the Clinical Progression of Parkinson’s Disease

B. Tang, Ji-feng Guo, Lu Shen, 2022, Frontiers in Aging Neuroscience.

Combination of optical coherence tomography (OCT) and OCT angiography increases diagnostic efficacy of Parkinson's disease.

Lu Shen, Yi Xu, Jing Zou, 2020, Quantitative imaging in medicine and surgery.

The role of frontotemporal dementia associated genes in patients with Alzheimer's disease

Jinchen Li, Lu Shen, Junling Wang, 2021, Neurobiology of Aging.

The role of vascular dementia associated genes in patients with Alzheimer's disease: A large case–control study in the Chinese population

Jinchen Li, Lu Shen, Junling Wang, 2021, CNS neuroscience & therapeutics.

Rare, pathogenic variants in LRP10 are associated with amyotrophic lateral sclerosis in patients from mainland China

Jinchen Li, B. Tang, Ling Huang, 2020, Neurobiology of Aging.

TOMM40 polymorphism is associated with resting-state functional MRI results in patients with Alzheimer's disease.

B. Tang, W. Liao, Youming Zhang, 2019, Neuroreport.

[Polynucleotide repeat expansion of nine spinocerebellar ataxia subtypes and dentatorubral-pallidoluysian atrophy in healthy Chinese Han population].

K. Xia, Q. Pan, B. Tang, 2010, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

Transglutaminase 6 interacts with polyQ proteins and promotes the formation of polyQ aggregates.

K. Xia, B. Tang, Hong Jiang, 2013, Biochemical and biophysical research communications.

Case-control study of the UCH-L1 S18Y variant in sporadic Parkinson’s disease in the Chinese population

K. Xia, Q. Pan, B. Tang, 2011, Journal of Clinical Neuroscience.

Age and Sex Affect Essential Tremor (ET) Plus: Clinical Heterogeneity in ET Based on the National Survey in China.

B. Tang, Ji-feng Guo, Jinsheng Lin, 2022, Aging and Disease.

Effect of the CYP2D6 and APOE Polymorphisms on the Efficacy of Donepezil in Patients with Alzheimer’s Disease: A Systematic Review and Meta-Analysis

B. Tang, Lu Shen, Bin Jiao, 2016, CNS Drugs.

Association study between SMPD1 p.L302P and sporadic Parkinson's disease in ethnic Chinese population.

B. Tang, Ji-feng Guo, Xinxiang Yan, 2015, International journal of clinical and experimental medicine.

Genetic analysis of Spinocerebellar ataxia type 17 in Parkinson's disease in Mainland China.

K. Xia, Q. Pan, B. Tang, 2010, Parkinsonism & related disorders.

A novel candidate locus on chromosome 11p14.1-p11.2 for autosomal dominant hereditary spastic paraplegia.

K. Xia, Q. Pan, B. Tang, 2008, Chinese medical journal.

[Analysis of CSF1R gene mutation in a Chinese family with hereditary diffuse leukoencephalopathy with neuroaxonal spheroids].

Lu Shen, Xiao-hua Gu, H. Zou, 2015, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.

A novel mutation in KCNQ2 gene causes benign familial neonatal convulsions in a Chinese family

K. Xia, Q. Pan, B. Tang, 2004, Journal of the Neurological Sciences.

Genetic and Pathological Characteristic Patterns of a Family With Neuronal Intranuclear Inclusion Disease.

Di Wu, Weiguo Liu, Lu Shen, 2020, Journal of neuropathology and experimental neurology.

Frequency of SCA1, SCA2, SCA3/MJD, SCA6, SCA7, and DRPLA CAG trinucleotide repeat expansion in patients with hereditary spinocerebellar ataxia from Chinese kindreds.

Q. Pan, H. Dai, B. Tang, 2000, Archives of neurology.

Expression of expanded GGC repeats within NOTCH2NLC causes cardiac dysfunction in mouse models

B. Tang, Hong Jiang, Lu Shen, 2023, Cell & Bioscience.

Polygenic determinants of Parkinson's disease in a Chinese population

Kai Li, Lu Shen, Hong Jiang, 2015, Neurobiology of Aging.

Association between marital status and cognitive impairment based on a cross‐sectional study in China

Guowei Huang, Yong Ji, Lu Shen, 2021, International journal of geriatric psychiatry.

A case of neurodegenerative disorder caused by PLA2G6 compound heterozygous pathogenic variant and SCA17 pathogenic variant

Lu Shen, J. Du, Qijie Yang, 2022, Neurological Sciences.

UQCRC1 variants in Parkinson's disease: A large cohort study in Chinese mainland population.

B. Tang, Zhenghuan Fang, Ji-feng Guo, 2021, Brain : a journal of neurology.

Mitochondrial genome variations are associated with amyotrophic lateral sclerosis in patients from mainland China

Mingyu Liang, B. Tang, Hong Jiang, 2021, Journal of Neurology.

Mutational spectrum and clinical features of GBA1 variants in a Chinese cohort with Parkinson’s disease

B. Tang, Ji-feng Guo, Xinxiang Yan, 2023, npj Parkinson's Disease.

Mutations in GBA, SNCA, and VPS35 are not associated with Alzheimer’s disease in a Chinese population: a case-control study

Lu Shen, Junling Wang, Bin Jiao, 2021, Neural regeneration research.

Research on screening and identification of proteins interacting with ataxin-3.

K. Xia, Q. Pan, B. Tang, 2005, Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.