M. Harwood

发表

Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis

S. Neuhoff, H. Crewe, H. Burt, 2016, Drug Metabolism and Disposition.

Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.

A Rostami-Hodjegan, G. Warhurst, A. Rostami-Hodjegan, 2013, Biopharmaceutics & drug disposition.

The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model.

Masoud Jamei, David B Turner, Amin Rostami-Hodjegan, 2017, Journal of pharmaceutical sciences.

Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine

Pamela J Davies, G. Warhurst, A. Rostami-Hodjegan, 2020, Drug Metabolism and Disposition.

Comparison of P-glycoprotein-mediated drug-digoxin interactions in Caco-2 with human and rodent intestine: relevance to in vivo prediction.

A. Collett, G. Warhurst, J. Tanianis-Hughes, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Application of proteomic data in the translation of in vitro observations to associated clinical outcomes

A. Rostami-Hodjegan, B. Achour, S. Neuhoff, 2021, Drug Discovery Today: Technologies.

In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2016, Drug Metabolism and Disposition.

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.

K Rowland-Yeo, M Jamei, L Almond, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

DMD058446 1766..1772

G. Warhurst, A. Rostami-Hodjegan, S. Neuhoff, 2014 .

Investigation of Regional Mechanisms Responsible for Poor Oral Absorption in Humans of a Modified Release Preparation of the (cid:1) -Adrenoreceptor Antagonist, 4-Amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 (UK-338,003): The Rational Use of ex Vivo Intestine to Predict in Vivo Absorption

A. Collett, G. Warhurst, M. Harwood, 2007 .

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

Talia Flanagan, Clive G. Wilson, Mai Anh Nguyen, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Towards a fully mechanistic prediction of oral drug absorption: Investigating intestinal transporter abundance and function relationships

M. Harwood, 2015 .

The Regional-Specific Relative and Absolute Expression of Gut Transporters in Adult Caucasians: A Meta-Analysis

Sibylle Neuhoff, S. Neuhoff, M. Harwood, 2019, Drug Metabolism and Disposition.

Absorption of taurocholic acid by the ileum of normal and transgenic ΔF508 cystic fibrosis mice

M. Harwood, C. Taylor, J. Hardcastle, 2004, The Journal of pharmacy and pharmacology.

Small intestinal glucose absorption in cystic fibrosis: a study in human and transgenic ΔF508 cystic fibrosis mouse tissues

M. Harwood, C. Taylor, J. Hardcastle, 2004, The Journal of pharmacy and pharmacology.

Application of an LC-MS/MS method for the simultaneous quantification of human intestinal transporter proteins absolute abundance using a QconCAT technique.

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2015, Journal of pharmaceutical and biomedical analysis.

Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics

G. Warhurst, A. Rostami-Hodjegan, B. Achour, 2020, Clinical pharmacology and therapeutics.

Alternative fusion protein strategies to express recalcitrant QconCAT proteins for quantitative proteomics of human drug metabolizing enzymes and transporters.

A. Rostami-Hodjegan, B. Achour, M. Russell, 2013, Journal of proteome research.

Lost in Centrifugation: Accounting for Transporter Protein Losses in Quantitative Targeted Absolute Proteomics

G. Warhurst, A. Rostami-Hodjegan, S. Neuhoff, 2014, Drug Metabolism and Disposition.

In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition

Amin Rostami-Hodjegan, Gordon Carlson, Brahim Achour, 2016, Drug Metabolism and Disposition.

Abnormal contraction caused by expression of G(i)-coupled receptor in transgenic model of dilated cardiomyopathy.

B. Conklin, C. Redfern, A. Baker, 2001, American journal of physiology. Heart and circulatory physiology.

Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome

X. Chu, J. Wiśniewski, S. Neuhoff, 2023, Molecular pharmaceutics.

Investigation of Regional Mechanisms Responsible for Poor Oral Absorption in Humans of a Modified Release Preparation of the α-Adrenoreceptor Antagonist, 4-Amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridyl)quinazoline (UK-338,003): The Rational Use of ex Vivo

A. Collett, G. Warhurst, M. Harwood, 2008, Drug Metabolism and Disposition.

Clive G. Wilson, A. Peer, H. Lennernäs, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.