J. Comer

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The intrinsic aqueous solubility of indomethacin

J. Dearden, J. Goodman, J. Comer, 2014 .

Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution--a validation study.

J. Comer, K. Box, K. Takács-Novák, 2006, Journal of pharmaceutical sciences.

Permeability through DOPC/dodecane membranes: measurement and LFER modelling.

John Comer, James A Platts, Karl Box, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

pH-Metric log P. 3. Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances

John Comer, Alex Avdeef, A. Avdeef, 1993 .

5.16 – Ionization Constants and Ionization Profiles

J. Comer, 2007 .

Potentiometric and spectrophotometric pKa determination of water-insoluble compounds: validation study in a new cosolvent system.

E. Bosch, J. Comer, K. Box, 2007, Analytica chimica acta.

A versatile potentiometric analyzer. Part two. Multiple known addition and Gran titration techniques.

A. Avdeef, J. Comer, 1987 .

Physicochemical Properties of a New Multicomponent Cosolvent System for the pKa Determination of Poorly Soluble Pharmaceutical Compounds

E. Bosch, M. Rosés, J. Comer, 2007 .

PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent-water mixtures.

A. Avdeef, K. Tam, J. Comer, 1999, Journal of pharmaceutical and biomedical analysis.

pH-Metric logP 10. Determination of Liposomal Membrane-Water Partition Coefficients of lonizable Drugs

A. Avdeef, K. Tam, J. Comer, 1998, Pharmaceutical Research.

Ionization Constants and Ionization Profiles

David T. Manallack, D. Manallack, J. Comer, 2007 .

New Ideas about the Solubility of Drugs

Karl Box, J. Comer, K. Box, 2009, Chemistry & biodiversity.

High-throughput measurement of pKa values in a mixed-buffer linear pH gradient system.

John Comer, Karl Box, A. Hill, 2003, Analytical chemistry.

pH-metric log P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values.

A. Avdeef, J. Comer, B. Slater, 1994, Journal of pharmaceutical sciences.

Lipophilicity measurements by liquid chromatography.

J. Comer, S. Gocan, G. Cimpan, 2006, Advances in chromatography.

Application of hydrogen bonding calculations in property based drug design.

Adam Ibrahim, John Comer, Michael H Abraham, 2002, Drug discovery today.

Novel ion-selective electrode system for the simultaneous determination of fluoride and calcium in acid solution.

J. Comer, J. E. Tyler, 1985, The Analyst.

Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound.

J. Comer, K. Takács-Novák, E. Baka, 2008, Journal of Pharmaceutical and Biomedical Analysis.

Using measured pKa, LogP and solubility to investigate supersaturation and predict BCS class.

J. Comer, K. Box, 2008, Current drug metabolism.

Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs.

K. Tam, J. Comer, R I Allen, 1998, Journal of pharmaceutical and biomedical analysis.

High‐Throughput Measurement of log D and pKa

John Comer, J. Comer, 2004 .

The sodium responsive tungsten bronze electrode: An electrode for sodium ion analysis of DNA solutions

J. Comer, J. V. Dobson, 1987 .

pH electrode performance under automated management conditions

J. E. A. Comer, C. Hibbert, J. Comer, 1997, The Journal of automatic chemistry.

Small-Scale Assays for Studying Dissolution of Pharmaceutical Cocrystals for Oral Administration

John Comer, Nikoletta Fotaki, Robert Price, 2016, AAPS PharmSciTech.

Lipophilicity Profiles: Theory and Measurement

John Comer, Kin Yip Tam, K. Tam, 2007 .

Presentation of a structurally diverse and commercially available drug data set for correlation and benchmarking studies.

T. Lundstedt, A. Hallberg, S. Winiwarter, 2006, Journal of medicinal chemistry.

The " dissolution" method: a low volume, in vitro apparatus for assessing the dissolution/precipitation behaviour of an active pharmaceutical ingredient under biorelevant conditions.

John Comer, Karl Box, J. Comer, 2011, Analytical methods : advancing methods and applications.

Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship.

J. Comer, Karl J Box, Krisztina Takács-Novák, 2010, Analytica chimica acta.

Correlations between PAMPA Permeability and log P

John Comer, Karl Box, J. Comer, 2007 .

High-Throughput Measurement of Drug pKa Values for ADME Screening

J. Comer, K. Box, 2003 .

Structure-Lipophilicity Relationships of Neutral and Protonated β-Blockers, Part I, Intra- and Intermolecular Effects in Isotropic Solvent Systems

H. Girault, P. Carrupt, B. Testa, 1999 .

High-Throughput Measurement of Drug pKa Values for ADME Screening:

J. Comer, K. Box, 2003 .

Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs.

K. Tam, J. Comer, K. Box, 1998, Journal of pharmaceutical and biomedical analysis.

Validation of pH-Metric Technique for Measurement of pKa and log Pow of Ionizable Herbicides

K. Chamberlain, J. Comer, A. A. Evans, 1995 .

Measurement of pKa and log P of water-insoluble substances by potentiometric titration

A. Avdeef, J. Comer, 1993 .