A. Ashton

C. D. Roche, A. Ashton, C. Gentile, 2020, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Inhibition of Tumor Necrosis Factor α-mediated NFκB Activation and Leukocyte Adhesion, with Enhanced Endothelial Apoptosis, by G Protein-linked Receptor (TP) Ligands*

A. Ashton, J. Ware, D. Kaul, 2003, The Journal of Biological Chemistry.

Endothelial Cell Activation in Patients With Decompensated Heart Failure

T. LeJemtel, U. Jorde, J. Banchs, 2005, Circulation.

Evaluation of first trimester serum soluble endothelial cell-specific tyrosine kinase receptor in normal and affected pregnancies

Jonathan M Morris, C. Roberts, N. Nassar, 2015, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

Protein Kinase Cδ Inhibition of S-Phase Transition in Capillary Endothelial Cells Involves the Cyclin-dependent Kinase Inhibitor p27Kip1 *

C. Albanese, R. Pestell, G. Watanabe, 1999, The Journal of Biological Chemistry.

Use of Skeletal Myoblasts for the Treatment of Chronic Heart Failure

R. Michler, A. Ashton, D. D'Alessandro, 2007 .

Asthma is not only an airway disease, but also a vascular disease.

J. Burgess, A. Ashton, L. Harkness, 2015, Pharmacology & therapeutics.

Polymorphism in Endothelial Connexin40 Enhances Sensitivity to Intraluminal Pressure and Increases Arterial Stiffness

C. Hill, B. Nicholson, K. Matthaei, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Dysregulation of Oxygen Sensing/Response Pathways in Pregnancies Complicated by Idiopathic Intrauterine Growth Restriction and Early-Onset Preeclampsia

Jonathan M Morris, A. Ashton, E. Gallery, 2022, International journal of molecular sciences.

Thromboxane A2 Receptor Signaling Inhibits Vascular Endothelial Growth Factor–Induced Endothelial Cell Differentiation and Migration

A. Ashton, J. Ware, 2004, Circulation research.

Myocardial regeneration - the revolution continues

A. Ashton, P. Wilczek, M. Zembala, 2007 .

Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug.

Pojen P. Chen, J. Rand, Xiao-Xuan Wu, 2010, Blood.

Taking the BAD out of adrenergic stimulation.

K. Mani, R. Kitsis, A. Ashton, 2002, Journal of molecular and cellular cardiology.

ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance

J. Pollard, R. Kitsis, I. Mercier, 2005, Cell Death and Differentiation.

Trypanosoma cruzi invasion is associated with trogocytosis.

L. Weiss, H. Tanowitz, A. Mukhopadhyay, 2015, Microbes and infection.

Role of Nongenomic Signaling Pathways Activated by Aldosterone During Cardiac Reperfusion Injury.

C. Gomez-Sanchez, M. Morel-Kopp, A. Mihailidou, 2015, Molecular endocrinology.

Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling

A. James, N. T. ten Hacken, W. Timens, 2018, Journal of cellular and molecular medicine.

Chronic Hypoxia Decreases Endothelial Connexin 40, Attenuates Endothelium‐Dependent Hyperpolarization–Mediated Relaxation in Small Distal Pulmonary Arteries, and Leads to Pulmonary Hypertension

J. Yuan, A. Makino, Makiko Watanabe, 2020, Journal of the American Heart Association.

Non-Genomic Effects of Aldosterone.

A. Mihailidou, A. Tzakos, A. Ashton, 2019, Vitamins and hormones.

Systematic review of first-trimester vitamin D normative levels and outcomes of pregnancy.

Jonathan M Morris, C. Roberts, N. Nassar, 2011, American journal of obstetrics and gynecology.

The Role and Regulation of Thromboxane A2 Signaling in Cancer-Trojan Horses and Misdirection

K. Honn, A. Ashton, Yunjia Zhang, 2022, Molecules.

The thromboxane synthase and receptor signaling pathway in cancer: an emerging paradigm in cancer progression and metastasis

K. Honn, W. Lambiv, A. Ashton, 2011, Cancer and Metastasis Reviews.

Levels of soluble fms-like tyrosine kinase one in first trimester and outcomes of pregnancy: a systematic review

Jonathan M Morris, C. Roberts, N. Nassar, 2011, Reproductive biology and endocrinology : RB&E.

Loss of Functional Endothelial Connexin40 Results in Exercise-Induced Hypertension in Mice

S. Bröer, C. Hill, S. K. Morton, 2015, Hypertension.

The Renaissance of CDK Inhibitors in Breast Cancer Therapy: An Update on Clinical Trials and Therapy Resistance

R. Pestell, X. Jiao, A. Ashton, 2022, Cancers.

Analyzing Trophoblast Function Using Cell-Based Assays.

A. Ashton, K. Powell, Katie L. Powell, 2018, Methods in molecular biology.

Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions.

S. Korsmeyer, K. Mani, R. Kitsis, 2004, Molecular cell.

NF-kB Regulation in T-cells in Pregnancy is Mediated via Fas/FasL Interactions: The Signal for which is Derived from Exosomes Present in Maternal Plasma

Jonathan M Morris, A. Ashton, K. Hadfield, 2016 .

Mechanisms Governing Metabolic Heterogeneity in Breast Cancer and Other Tumors

R. Pestell, X. Jiao, D. Joyce, 2021, Frontiers in Oncology.

Cyclin D1 governs adhesion and motility of macrophages.

Amanda Y. Chan, M. Symons, M. Cammer, 2003, Molecular biology of the cell.

Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2

M. Desruisseaux, L. Weiss, H. Tanowitz, 2018, Infection and Immunity.

Identification of a functional prostanoid-like receptor in the protozoan parasite, Trypanosoma cruzi

D. Spray, M. Lisanti, L. Weiss, 2013, Parasitology Research.

Role for the thromboxane A2 receptor β-isoform in the pathogenesis of intrauterine growth restriction

A. Simpson, Yan Cheng, A. Ashton, 2016, Scientific Reports.

Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.

E. Garrett-Mayer, D. Watson, P. Halushka, 2008, Cancer research.

Thymidine Phosphorylase and 2-Deoxyribose Stimulate Human Endothelial Cell Migration by Specific Activation of the Integrins α5β1 and αVβ3*

K. Hotchkiss, E. Schwartz, A. Ashton, 2003, Journal of Biological Chemistry.

Mechanisms by which tumor cells and monocytes expressing the angiogenic factor thymidine phosphorylase mediate human endothelial cell migration.

K. Hotchkiss, E. Schwartz, R. Klein, 2003, Cancer research.

An Update on Glioblastoma Biology, Genetics, and Current Therapies: Novel Inhibitors of the G Protein-Coupled Receptor CCR5

R. Pestell, X. Jiao, D. Joyce, 2021, International journal of molecular sciences.

Regulated suppression of NF-κB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success.

A. Ashton, K. Hadfield, S. Mccracken, 2011, Journal of reproductive immunology.

Fibroblast Growth Factor-2 Induces Lef/Tcf-dependent Transcription in Human Endothelial Cells*

K. Wolff, C. Albanese, P. Neumeister, 2002, The Journal of Biological Chemistry.

Cardiac effects of aldosterone: Does gender matter?

A. Mihailidou, A. Ashton, Anastasia S. Mihailidou, 2014, Steroids.

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses

N. Schultz, K. Iczkowski, H. Rui, 2023, Research square.

Pparγ1 Facilitates ErbB2-Mammary Adenocarcinoma in Mice

W. Tong, A. Kossenkov, Chenguang Wang, 2021, Cancers.

The G protein coupled receptor CCR5 in cancer.

A. Kossenkov, R. Pestell, X. Jiao, 2020, Advances in cancer research.

The Apoptosis Inhibitor ARC Undergoes Ubiquitin-Proteasomal-mediated Degradation in Response to Death Stimuli

K. Mani, R. Kitsis, R. Foo, 2007, Journal of Biological Chemistry.

Embryonic/fetal mortality and intrauterine growth restriction is not exclusive to the CBA/J sub-strain in the CBA × DBA model

A. Ashton, K. McKelvey, S. Mccracken, 2016, Scientific Reports.

Low-Dose Spironolactone Prevents Apoptosis Repressor With Caspase Recruitment Domain Degradation During Myocardial Infarction

A. Mihailidou, J. Funder, V. Howell, 2012, Hypertension.

Abstract 313: Regulation of p53 Tetramerization and Nuclear Export by ARC

I. Ellis, S. Chin, C. Caldas, 2006 .

Exosomes: Mechanisms of Uptake

A. Ashton, Anthony W. Ashton, K. McKelvey, 2015, Journal of circulating biomarkers.

Inhibition of endothelial cell function in vitro and angiogenesis in vivo by docetaxel (Taxotere): association with impaired repositioning of the microtubule organizing center.

Edward L Schwartz, K. Hotchkiss, J. Sparano, 2002, Molecular cancer therapeutics.

Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli.

S. Woodman, M. Lisanti, J. Wyckoff, 2003, The American journal of pathology.

The membrane-associated form of cyclin D1 enhances cellular invasion

S. Achilefu, H. Rui, M. Lisanti, 2020, Oncogenesis.

Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3.

K. Hotchkiss, E. Schwartz, A. Ashton, 2003, The Journal of biological chemistry.

Inhibition of Endothelial Cell Migration, Intercellular Communication, and Vascular Tube Formation by Thromboxane A2 *

D. Spray, A. Ashton, S. Suadicani, 1999, The Journal of Biological Chemistry.

Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy

D. Ni, D. Speicher, R. Pestell, 2021, Breast cancer research : BCR.

Mechanisms of Hepatocyte Growth Factor–Mediated Vascular Smooth Muscle Cell Migration

J. Berman, Harry Ma, T. Calderon, 2003, Circulation research.

Perspectives on the Trypanosoma cruzi–host cell receptor interactions

Huan Huang, J. Scharfstein, M. Lima, 2009, Parasitology Research.

Sex Differences in Sudden Cardiac Death

A. Mihailidou, A. Ashton, R. Ritchie, 2013 .

Angiopoietin 1 and 2 serum concentrations in first trimester of pregnancy as biomarkers of adverse pregnancy outcomes.

C. Roberts, N. Nassar, A. Ashton, 2014, American journal of obstetrics and gynecology.

Effects of maternal serum 25-hydroxyvitamin D concentrations in the first trimester on subsequent pregnancy outcomes in an Australian population.

J. Simpson, C. Roberts, N. Nassar, 2014, The American journal of clinical nutrition.

First trimester screening of serum soluble fms-like tyrosine kinase-1 and placental growth factor predicting hypertensive disorders of pregnancy.

C. Roberts, N. Nassar, A. Ashton, 2013, Pregnancy hypertension.

First trimester screening of maternal placental protein 13 for predicting preeclampsia and small for gestational age: in-house study and systematic review.

J. Morris, C. Roberts, N. Nassar, 2012, Placenta.

Biopsy coupled to quantitative immunofluorescence: a new method to study the human vascular endothelium.

J. Banchs, A. Ashton, J. Ware, 2002, Journal of applied physiology.

Source of angiopoietin-2 in the sera of women during pregnancy.

J. Morris, C. Kan, A. Ashton, 2012, Microvascular research.

HuR/Cx40 downregulation causes coronary microvascular dysfunction in type 2 diabetes

J. Yuan, A. Makino, Makiko Watanabe, 2021, JCI insight.

HuR-mediated posttranscriptional modification of Cx40 and coronary microvascular dysfunction in type 2 diabetes

J. Yuan, A. Makino, Makiko Watanabe, 2021 .

Tbx6 is a determinant of cardiac and neural cell fate decisions in multipotent P19CL6 cells.

C. Mummery, Klitos Konstantinidis, R. Kitsis, 2012, Differentiation; research in biological diversity.

Role of androgens in sex differences in cardiac damage during myocardial infarction.

David Handelsman, A. Mihailidou, J. Funder, 2014, Endocrinology.

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses

N. Schultz, K. Iczkowski, H. Rui, 2023, Oncogene.

Utility of metabolic profiling of serum in the diagnosis of pregnancy complications.

A. S. Stephens, A. Dona, A. Ashton, 2018, Placenta.

Exosomes : Mechanisms of Uptake Review Article

A. Ashton, K. McKelvey, K. Powell, 2016 .

Thromboxane A2 Receptor Agonists Antagonize the Proangiogenic Effects of Fibroblast Growth Factor-2: Role of Receptor Internalization, Thrombospondin-1, and &agr;v&bgr;3

Yan Cheng, A. Ashton, J. Ware, 2004, Circulation research.

NF-κB regulation in maternal immunity during normal and IUGR pregnancies

A. Ashton, K. McKelvey, S. Mccracken, 2021, Scientific Reports.

Identification of a functional prostanoid-like receptor in the protozoan parasite, Trypanosoma cruzi

D. Spray, M. Lisanti, L. Weiss, 2013, Parasitology Research.

Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1).

C. Albanese, R. Pestell, G. Watanabe, 1999, The Journal of biological chemistry.

Anthrax Lethal Toxin Kills Macrophages in a Strain-Specific Manner by Apoptosis or Caspase-1-Mediated Necrosis

Steven A. Porcelli, Michael P. Lisanti, M. Lisanti, 2007, Cell cycle.

Tumstatin regulates the angiogenic and inflammatory potential of airway smooth muscle extracellular matrix

J. Burgess, M. Kopp, A. Ashton, 2017, Journal of cellular and molecular medicine.

Angiogenic regulatory influence of extracellular matrix deposited by resting state asthmatic and non‐asthmatic airway smooth muscle cells is similar

A. James, P. Horvatovich, J. Burgess, 2021, Journal of cellular and molecular medicine.

Preparing to strike: Acute events in signaling by the serpentine receptor for thromboxane A2.

A. Ashton, 2023, Pharmacology & therapeutics.

Acetylation of nuclear receptors in health and disease: an update

Z. Dosztányi, R. Pestell, Zhiping Li, 2022, The FEBS journal.

Cardiac effects of aldosterone: Does gender matter?

A. Mihailidou, A. Ashton, 2014, Steroids.

Inhibition of tumor necrosis factor alpha-mediated NFkappaB activation and leukocyte adhesion, with enhanced endothelial apoptosis, by G protein-linked receptor (TP) ligands.

A. Ashton, J. Ware, D. Kaul, 2003, The Journal of biological chemistry.

Angiopoietin 1 and 2 serum concentrations in first trimester of pregnancy as biomarkers of adverse pregnancy outcomes.

C. Roberts, N. Nassar, A. Ashton, 2014, American journal of obstetrics and gynecology.