J. Kaplan

发表

Characterization of Yeast Methyl Sterol Oxidase (ERG25) and Identification of a Human Homologue*

Liangtao Li, J. Kaplan, J Kaplan, 1996, The Journal of Biological Chemistry.

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin.

M. Pandolfo, L. Montermini, S. Jiralerspong, 1997, Science.

Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI‐ceruloplasmin

G. Musci, J. Kaplan, S. David, 2007, The EMBO journal.

Regulation of iron acquisition and storage: consequences for iron-linked disorders

Jerry Kaplan, J. Kaplan, D. Ward, 2008, Nature Reviews Molecular Cell Biology.

Iron Regulatory Protein-1 Protects against Mitoferrin-1-deficient Porphyria*

B. Paw, M. Hentze, A. Lambert, 2014, The Journal of Biological Chemistry.

Chediak-Higashi syndrome: a clinical and molecular view of a rare lysosomal storage disorder.

J. Kaplan, D. Ward, Shelly L Shiflett, 2002, Current molecular medicine.

Effect of volume and pH on surface receptor number in macrophages

J. M. Novak, S. Buys, L. Gren, 1989, Journal of cellular physiology.

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

B. Paw, O. Shirihai, Prasad N. Paradkar, 2009, Proceedings of the National Academy of Sciences.

Iron‐depletion limits intracellular bacterial growth in macrophages

Prasad N. Paradkar, I. Zohn, J. Kaplan, 2008, Blood.

Iron-dependent metabolic remodeling in S. cerevisiae.

C. Philpott, J. Kaplan, D. McVey Ward, 2006, Biochimica et biophysica acta.

Regulatory oversight of the iron trade: posttranscriptional regulation in yeast.

Craig D. Kaplan, C. Kaplan, J. Kaplan, 2005, Cell metabolism.

Control of Parasitophorous Vacuole Expansion by LYST/Beige Restricts the Intracellular Growth of Leishmania amazonensis

Kathleen A. Kennedy, C. Huynh, A. Aderem, 2008, PLoS pathogens.

Chediak-Higashi syndrome

J. Kaplan, I. De Domenico, D. Ward, 2008, Current opinion in hematology.

The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C.

D. Kabelitz, D. Adam, J. Kaplan, 2007, Experimental cell research.

Use of Expression Constructs to Dissect the Functional Domains of the CHS/Beige Protein: Identification of Multiple Phenotypes

G. Prestwich, J. Kaplan, D. Ward, 2003, Traffic.

Chediak-Higashi Syndrome: a rare disorder of lysosomes and lysosome related organelles.

J. Kaplan, D. Ward, Shelly L Shiflett, 2002, Pigment cell research.

Chédiak–Higashi Syndrome

C. Perou, J. Kaplan, 1998 .

The Beige/Chediak-Higashi Syndrome Gene Encodes a Widely Expressed Cytosolic Protein*

C. Perou, Liangtao Li, J. Kaplan, 1997, The Journal of Biological Chemistry.

Identification of a Candida albicans Ferrichrome Transporter and Its Characterization by Expression inSaccharomyces cerevisiae *

H. Bussey, C. Philpott, J. Kaplan, 2001, The Journal of Biological Chemistry.

Specific iron chelators determine the route of ferritin degradation.

J. Kaplan, I. De Domenico, D. Ward, 2009, Blood.

Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblasts.

D. Radisky, J. Kaplan, 1998, The Biochemical journal.

Human ESCRT-II Complex and Its Role in Human Immunodeficiency Virus Type 1 Release

R. D. Fisher, W. Sundquist, C. Hill, 2006, Journal of Virology.

The Protein Network of HIV Budding

W. Sundquist, H. Kräusslich, B. Müller, 2003, Cell.

Autophagy, ferritin and iron chelation

J. Kaplan, I. De Domenico, D. McVey Ward, 2010, Autophagy.

hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif.

D. Radisky, J. Kaplan, D. Ward, 2001, Experimental cell research.

A Mitochondrial-Vacuolar Signaling Pathway in Yeast That Affects Iron and Copper Metabolism*

Liangtao Li, J. Kaplan, 2004, Journal of Biological Chemistry.

Modulation of lysosomal enzyme levels in cultured cells: effects of alterations in cell density, balanced growth, and endocytosis.

J. Kaplan, 1978, Archives of biochemistry and biophysics.

Ferroportin-mediated iron transport: expression and regulation.

J. Kaplan, D. Ward, 2012, Biochimica et biophysica acta.

Fusion of sequentially internalized vesicles in alveolar macrophages

J. Kaplan, D. Ward, D. P. Hackenyos, 1990, The Journal of cell biology.

Inhibition of late endosome‐lysosome fusion: Studies on the mechanism by which isotonic‐K+ buffers alter intracellular ligand movement

J. Kaplan, S. Davis-Kaplan, D. Ward, 1990, Journal of cellular physiology.

Characterization of endocytic compartments using the horseradish peroxidase-diaminobenzidine density shift technique

J. Kaplan, R. Ajioka, 1987, The Journal of cell biology.

Receptor assay with radiolabeled transferrin.

J. Kaplan, J. H. Ward, 1987, Methods in enzymology.

Effect of phagocytosis on receptor distribution and endocytic activity in macrophages

S. Buys, J. Kaplan, 1987, Journal of cellular physiology.

Phenylarsine oxide-induced increase in alveolar macrophage surface receptors: evidence for fusion of internal receptor pools with the cell surface

H. Wiley, J. Kaplan, D. Ward, 1985, The Journal of cell biology.

STUDIES ON THE PHYSIOLOGY OF MACROPHAGE RECEPTORS FOR α‐MACROGLOBULIN · PROTEASE COMPLEXES a

J. Kaplan, E. Keogh, 1983 .

Lysosome Biogenesis and Dynamics

J. Kaplan, D. Ward, Shelly L. Shiflett, 2005 .

Conventional and Secretory Lysosomes

J. Kaplan, D. Ward, R. Shrestha, 2016 .

Analysis of the Lysosomal Storage Disease Chediak–Higashi Syndrome

J. Kaplan, G. Griffiths, J. Stinchcombe, 2000, Traffic.

Mon1a Protein Acts in Trafficking through the Secretory Apparatus*

Prasad N. Paradkar, J. Kaplan, D. Ward, 2012, The Journal of Biological Chemistry.

Murine macrophages response to iron.

D. Girelli, O. Olivieri, A. D’Alessandro, 2012, Journal of proteomics.

The Ferroportin Metal Efflux Proteins Function in Iron and Cobalt Homeostasis in Arabidopsis[W][OA]

N. Grotz, M. Guerinot, B. Lahner, 2009, The Plant Cell Online.

Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice

N. Andrews, M. Fleming, W. Dietrich, 2007, Nature Genetics.

Functional studies of hephaestin in yeast: evidence for multicopper oxidase activity in the endocytic pathway.

C. Vulpe, Liangtao Li, J. Kaplan, 2003, The Biochemical journal.

CCC1 Suppresses Mitochondrial Damage in the Yeast Model of Friedreich's Ataxia by Limiting Mitochondrial Iron Accumulation*

J. Kaplan, O. Chen, 2000, The Journal of Biological Chemistry.

In vivo damage of rat lungs by oxygen metabolites.

P. Ward, K. Johnson, J. Fantone, 1981, The Journal of clinical investigation.

Polypeptide-binding membrane receptors: analysis and classification.

J. Kaplan, 1981, Science.

The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease.

Andrew Pollock, I. Zohn, L. Niswander, 2007, Blood.

Regulation of HeLa cell transferrin receptors.

J. Kushner, J. Kaplan, J. H. Ward, 1982, The Journal of biological chemistry.

Fam210b Is Required for Optimal Cellular and Mitochondrial Iron Uptake during Erythroid Differentiation

B. Paw, L. Zon, H. Lodish, 2015 .

The mitochondrial iron exporter genes MMT1 and MMT2 in yeast are transcriptionally regulated by Aft1 and Yap1

Liangtao Li, J. Kaplan, D. Ward, 2020, The Journal of Biological Chemistry.

Homotypic Lysosome Fusion in Macrophages: Analysis Using an In Vitro Assay

J. Kaplan, Jonathan D. Leslie, D. Ward, 1997, The Journal of cell biology.

Patterns in Receptor Behavior and Function

J. Kaplan, 1985 .

Leishmania-Mediated Inhibition of Iron Export Promotes Parasite Replication in Macrophages

D. C. Miguel, J. Kaplan, N. Andrews, 2014, PLoS pathogens.

The molecular mechanism of hepcidin-mediated ferroportin down-regulation.

W. Sundquist, T. Ganz, E. Nemeth, 2007, Molecular biology of the cell.

Snx3 regulates recycling of the transferrin receptor and iron assimilation.

B. Paw, H. Lodish, M. Freedman, 2013, Cell metabolism.

Hepcidin and ferroportin: the new players in iron metabolism.

J. Kaplan, I. De Domenico, D. Ward, 2011, Seminars in liver disease.

The molecular basis of hepcidin-resistant hereditary hemochromatosis.

T. Ganz, E. Nemeth, J. Kaplan, 2009, Blood.

Disorders of Iron MetabolismProgress in Hematology

G. Musci, J. Kaplan, D. Ward, 2006 .

Iron overload due to mutations in ferroportin.

G. Musci, J. Kaplan, I. De Domenico, 2006, Haematologica.

Evidence for the multimeric structure of ferroportin.

G. Musci, J. Kaplan, I. De Domenico, 2007, Blood.

Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes

B. Paw, G. Musso, J. Phillips, 2017, The Journal of Biological Chemistry.

Identiﬁcation of Distal cis -Regulatory Elements at Mouse Mitoferrin Loci Using Zebraﬁsh Transgenesis (cid:1)

B. Paw, A. Lambert, A. Cantor, 2011 .

The molecular basis of ferroportin-linked hemochromatosis.

T. Ganz, E. Nemeth, G. Musci, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Strategy and tactics in the evolution of iron acquisition.

J. Kaplan, 2002, Seminars in hematology.

A splicing defect in the mouse transferrin gene leads to congenital atransferrinemia.

C. Craven, R. Idzerda, G. McKnight, 1989, Blood.

The role of ubiquitination in hepcidin-independent and hepcidin-dependent degradation of ferroportin.

I. Hamza, J. Kaplan, I. De Domenico, 2011, Cell metabolism.

Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation.

J. Kaplan, I. De Domenico, D. Ward, 2010, Blood.

Two novel mutations in TpreMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child

J. Phillips, H. Yaish, J. Kaplan, 2017 .

Clinical, pathological, and molecular correlates in ferroportin disease: a study of two novel mutations.

D. Girelli, M. Ferrari, A. Castagna, 2008, Journal of Hepatology.

Hepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in mice.

Dean Y. Li, R. Daynes, J. Kushner, 2010, The Journal of clinical investigation.

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

J. Abkowitz, P. Kingsley, J. Palis, 2008, Science.

Iron absorption in hypotransferrinemic mice.

S. Buys, J. Kushner, J. Kaplan, 1991, Blood.

Source of iron in neutrophil-mediated killing of endothelial cells.

P. Ward, J. Varani, S. Phan, 1987, Laboratory investigation; a journal of technical methods and pathology.

A Multicopper Oxidase-Based Iron-Transport System in Yeast

J. Kaplan, 2002 .

Mining the genome for iron

J. Kushner, J. Kaplan, 2000, Nature.

Iron Transport in Yeast: The Involvement of an Iron Reductase and Oxidase

J. Kaplan, C. Askwith, 1998 .

Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes.

M. Justice, C. Perou, J. Kaplan, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Zebrafish as a model for defining the functional impact of mammalian ferroportin mutations.

J. Kushner, J. Kaplan, I. De Domenico, 2007, Blood.

Hepcidin is elevated in mice injected with Mycoplasma arthritidis

J. Kaplan, C. Koening, I. De Domenico, 2009, Journal of Inflammation.

Regulation of the Distribution of Tissue Iron

C. Craven, J. Lamb, J. Kushner, 1988, Annals of the New York Academy of Sciences.

Decoupling ferritin synthesis from free cytosolic iron results in ferritin secretion.

Prasad N. Paradkar, J. Kaplan, I. De Domenico, 2011, Cell metabolism.

Muscle specific iron deficiency has systemic consequences

J. Kaplan, D. Ward, 2015, EBioMedicine.

Transferrin receptor function in hereditary hemochromatosis.

J. Kushner, J. Kaplan, J. H. Ward, 1984, The Journal of laboratory and clinical medicine.

A new wrinkle in the fold: hepcidin links inflammation to the unfolded protein response.

J. Kaplan, I. De Domenico, 2009, Cell metabolism.

Analysis of macrophage surface receptors. II. Internalization of alpha-macroglobulin . trypsin complexes by rabbit alveolar macrophages.

J. Kaplan, M. Nielsen, 1979, The Journal of biological chemistry.

Analysis of macrophage surface receptors. I. Binding of alpha-macroglobulin . protease complexes to rabbit alveolar macrophages.

J. Kaplan, M. Nielsen, 1979, The Journal of biological chemistry.

The late chlamydial inclusion membrane is not derived from the endocytic pathway and is relatively deficient in host proteins

J. Kaplan, S. Davis-Kaplan, D. Ward, 1996, Infection and immunity.

"Synchronized" endocytosis and intracellular sorting in alveolar macrophages: the early sorting endosome is a transient organelle

C. Perou, C. Perou, J. Kaplan, 1995, The Journal of cell biology.

The rate of internalization of different receptor-ligand complexes in alveolar macrophages is receptor-specific.

J. Kaplan, D. Ward, 1990, The Biochemical journal.

Effect of hypo‐osmotic incubation on membrane recycling

J. M. Novak, S. Buys, J. Kaplan, 1988, Journal of cellular physiology.

Temperature shifts induce the selective loss of alveolar-macrophage plasma membrane components

J. Kaplan, E. Keogh, Jerry Kaplan, 1982, The Journal of cell biology.

Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.

B. Paw, J. Phillips, O. Khalimonchuk, 2011, Blood.

Inhibitory effects of tunicamycin on procollagen biosynthesis and secretion.

J. Kaplan, M. Tanzer, F. Rowland, 1977, Biochimica et biophysica acta.

Internalization and subcellular localization of transferrin and transferrin receptors in HeLa cells.

J. Kushner, J. Kaplan, J. Lamb, 1983, The Journal of biological chemistry.

An Oxidase-Permease-based Iron Transport System in Schizosaccharomyces pombe and Its Expression in Saccharomyces cerevisiae*

J. Kaplan, C. Askwith, 1997, The Journal of Biological Chemistry.

Molecular mechanisms of iron uptake in eukaryotes.

J. Kaplan, D. D. de Silva, C. Askwith, 1996, Physiological reviews.

PKR1 Encodes an Assembly Factor for the Yeast V-Type ATPase*

M. A. Compton, T. Stevens, J. Kaplan, 2006, Journal of Biological Chemistry.

Molecular Genetics of Chediak–Higashi Syndrome

J. Kaplan, D. Ward, 2013 .

Chediak-Higashi syndrome is not due to a defect in microtubule-based lysosomal mobility.

C. Perou, J. Kaplan, 1993, Journal of cell science.

The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice

B. Paw, M. Hockin, A. Earl, 2020, The Journal of Biological Chemistry.

Transcription of the Yeast Iron Regulon Does Not Respond Directly to Iron but Rather to Iron-Sulfur Cluster Biosynthesis*

M. Bard, D. Winge, M. Valachovič, 2004, Journal of Biological Chemistry.

Genetic and Biochemical Analysis of High Iron Toxicity in Yeast

Liangtao Li, J. Kaplan, D. Ward, 2010, The Journal of Biological Chemistry.

A Role for Iron-Sulfur Clusters in the Regulation of Transcription Factor Yap5-dependent High Iron Transcriptional Responses in Yeast*

Liangtao Li, J. Kaplan, D. Ward, 2012, The Journal of Biological Chemistry.

Iron acquisition and transcriptional regulation.

Craig D. Kaplan, C. Kaplan, J. Kaplan, 2009, Chemical reviews.

Transferrin receptors of human fibroblasts. Analysis of receptor properties and regulation.

J. Kushner, J. Kaplan, J. H. Ward, 1982, The Biochemical journal.

The GEF1 gene of Saccharomyces cerevisiae encodes an integral membrane protein; mutations in which have effects on respiration and iron-limited growth

D. Eide, B. Didomenico, J. Greene, 1993, Molecular and General Genetics MGG.

CCC1 Is a Transporter That Mediates Vacuolar Iron Storage in Yeast*

Jerry Kaplan, Liangtao Li, J. Kaplan, 2001, The Journal of Biological Chemistry.

Site-directed Mutagenesis of the Yeast Multicopper Oxidase Fet3p*

J. Kaplan, C. Askwith, Candice C. Askwith, 1998, The Journal of Biological Chemistry.

Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport

R. Klausner, D. Yuan, D. Eide, 1994, Cell.

Characterization of a transferrin-independent uptake system for iron in HeLa cells.

C. Craven, J. Kaplan, J. Lamb, 1990, The Journal of biological chemistry.

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Jerry Kaplan, Michael B. Vaughn, Elizabeta Nemeth, 2004, Science.

Ferroportin‐mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

G. Musci, Liangtao Li, J. Kaplan, 2006, The EMBO journal.

Zinc Pyrithione Inhibits Yeast Growth through Copper Influx and Inactivation of Iron-Sulfur Proteins

P. Hu, C. Saunders, T. Reichling, 2011, Antimicrobial Agents and Chemotherapy.

Deficiency of glutaredoxin 5 reveals Fe–S clusters are required for vertebrate haem synthesis

B. Paw, L. Zon, K. Dooley, 2005, Nature.

Heme regulation of HeLa cell transferrin receptor number.

J. Kushner, J. Kaplan, J. H. Ward, 1984, The Journal of biological chemistry.

The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake

P. Bernard, D. Eide, Liangtao Li, 1994, Cell.

Purification and Characterization of Fet3 Protein, a Yeast Homologue of Ceruloplasmin*

J. Kaplan, D. D. de Silva, S. Davis-Kaplan, 1997, The Journal of Biological Chemistry.

Defective organellar membrane protein trafficking in Ap3b1-deficient cells.

S. Mansour, J. Kaplan, C. Li, 2000, Journal of cell science.

Regulation of iron uptake in Saccharomyces cerevisiae. The ferrireductase and Fe(II) transporter are regulated independently.

D. Eide, J. Kaplan, D. Sipe, 1992, The Journal of biological chemistry.

The FET3 Gene Product Required for High Affinity Iron Transport in Yeast Is a Cell Surface Ferroxidase (*)

D. Eide, J. Kaplan, D. D. de Silva, 1995, The Journal of Biological Chemistry.

Regulation of Transition Metal Transport across the Yeast Plasma Membrane*

D. Radisky, J. Kaplan, 1999, The Journal of Biological Chemistry.

Tissue distribution and clearance kinetics of non-transferrin-bound iron in the hypotransferrinemic mouse: a rodent model for hemochromatosis.

C. Craven, J. Kushner, J. Kaplan, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux.

J. Kaplan, M. Troadec, I. De Domenico, 2010, Blood.

Development of a solid-phase assay for measurement of proteolytic enzyme activity.

J. Varani, K. Johnson, J. Kaplan, 1980, Analytical biochemistry.

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin.

Jerry Kaplan, Clara Camaschella, Laura Silvestri, 2008, Cell metabolism.

The mammalian transferrin-independent iron transport system may involve a surface ferrireductase activity.

J. Kaplan, I. Jordan, 1994, The Biochemical journal.

Iron Metabolism in Eukaryotes—Mars and Venus at It Again

T. O’Halloran, J. Kaplan, J Kaplan, 1996, Science.

Regulation of Mitochondrial Iron Import through Differential Turnover of Mitoferrin 1 and Mitoferrin 2

B. Paw, Prasad N. Paradkar, J. Kaplan, 2008, Molecular and Cellular Biology.

Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast.

W. B. Snyder, D. Radisky, S. Emr, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Chloride is an allosteric effector of copper assembly for the yeast multicopper oxidase Fet3p: an unexpected role for intracellular chloride channels.

D. Radisky, J. Kaplan, S. Davis-Kaplan, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Desferrioxamine-mediated Iron Uptake in Saccharomyces cerevisiae

D Botstein, D. Botstein, P. Brown, 2000, The Journal of Biological Chemistry.

YKE4 (YIL023C) Encodes a Bidirectional Zinc Transporter in the Endoplasmic Reticulum of Saccharomyces cerevisiae*

A. Kumánovics, J. Kaplan, D. Ward, 2006, Journal of Biological Chemistry.

Hepcidin regulation: ironing out the details.

Jerry Kaplan, J. Kaplan, I. De Domenico, 2007, The Journal of clinical investigation.

Mitoferrin is essential for erythroid iron assimilation

A. Brownlie, A. Donovan, B. Paw, 2006, Nature.

Localization of Iron in Arabidopsis Seed Requires the Vacuolar Membrane Transporter VIT1

Jerry Kaplan, Tracy Punshon, Antonio Lanzirotti, 2006, Science.

Studies on the turnover of plasma membranes in cultured mammalina cells. I. Rates of synthesis and degradation of plasma membrane proteins and carbohydrates.

J. Kaplan, M. Moskowitz, 1975, Biochimica et biophysica acta.

ferroportin: structure-function study The N-terminus of hepcidin is essential for its interaction with

A. Waring, T. Ganz, E. Nemeth, 2013 .

Mechanisms of Cellular Iron Acquisition Another Iron in the Fire

J. Kaplan, 2002, Cell.

Genome-wide Analysis of Iron-dependent Growth Reveals a Novel Yeast Gene Required for Vacuolar Acidification*

J. Kaplan, S. Davis-Kaplan, D. Ward, 2004, Journal of Biological Chemistry.

Alteration in the organ distribution of iron by truncated transferrin: implications for iron chelation therapy.

J. Kaplan, L. Li, 1997, The Journal of laboratory and clinical medicine.

Erythropoietin signaling regulates heme biosynthesis

B. Paw, H. Lodish, S. Orkin, 2016, eLife.

Genetic analysis of iron citrate toxicity in yeast: Implications for mammalian iron homeostasis

J. Kaplan, O. Chen, Shawn Hemenway, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Identification of Distal cis-Regulatory Elements at Mouse Mitoferrin Loci Using Zebrafish Transgenesis

B. Paw, A. Lambert, A. Cantor, 2011, Molecular and Cellular Biology.

Recognition of nucleophile-treated alpha 2-macroglobulin by the alveolar macrophage alpha-macroglobulin . protease complex receptor.

J. Kaplan, E. Keogh, F. Ray, 1981, The Journal of biological chemistry.

The hepcidin-binding site on ferroportin is evolutionarily conserved.

T. Ganz, J. Phillips, E. Nemeth, 2008, Cell metabolism.

The molecular basis of iron overload disorders and iron-linked anemias

J. Kaplan, D. Ward, I. Domenico, 2011, International journal of hematology.

The Enlarged Lysosomes in beigej Cells Result From Decreased Lysosome Fission and Not Increased Lysosome Fusion

D. Adam, J. Kaplan, D. Ward, 2012, Traffic.

Grey, a novel mutation in the murine Lyst gene, causes the beige phenotype by skipping of exon 25

H. Büssow, G. Cox, F. Runkel, 2006, Mammalian Genome.

Bph1p, the Saccharomyces cerevisiae Homologue of CHS1/Beige, Functions in Cell Wall Formation and Protein Sorting

J. Kaplan, D. Ward, Dinh Huynh, 2004, Traffic.

The bg allele mutation is due to a LINE1 element retrotransposition.

T. Naas, C. Perou, J. Kaplan, 1997, Genomics.

Identification of the murine beige gene by YAC complementation and positional cloning

M. Justice, T. Brody, G. Duyk, 1996, Nature Genetics.

Defective lysosomal exocytosis and plasma membrane repair in Chediak-Higashi/beige cells.

Jerry Kaplan, Chau Huynh, C. Huynh, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Comparative mapping in the beige-satin region of mouse chromosome 13.

M. Justice, C. Perou, J. Kaplan, 1997, Genomics.

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

B. Paw, L. Zon, H. Lodish, 2018, The Journal of Biological Chemistry.

Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria.

B. Paw, J. Bloomer, Liangtao Li, 2011, Experimental hematology.

Two novel mutations in TMPRSS6 associated with iron-refractory iron deficiency anemia in a mother and child.

J. Phillips, H. Yaish, J. Kaplan, 2017, Blood cells, molecules & diseases.

Complementation analysis of Chediak-Higashi Syndrome: The same gene may be responsible for the defect in all patients and species

C. Perou, J. Kaplan, 1993, Somatic cell and molecular genetics.

Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.

W. Sundquist, E. Morita, J. Skalicky, 2008, Developmental cell.

TMEM14C is required for erythroid mitochondrial heme metabolism.

Jerry Kaplan, Harvey F Lodish, Daniel E Bauer, 2014, The Journal of clinical investigation.

Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.

Jerry Kaplan, Roland Nilsson, Kathleen A Soltis, 2009, Cell metabolism.

Analysis of the effect of amines on inhibition of receptor-mediated and fluid-phase pinocytosis in rabbit alveolar macrophages

J. Kaplan, E. Keogh, 1981, Cell.

Inhibition of Heme Biosynthesis Prevents Transcription of Iron Uptake Genes in Yeast*

Y. Yamaguchi-Iwai, C. Galea, J. Kaplan, 2003, Journal of Biological Chemistry.

The Yeast Frataxin Homologue Mediates Mitochondrial Iron Efflux

D. Radisky, J. Kaplan, M. Babcock, 1999, The Journal of Biological Chemistry.

Frataxin knockin mouse

Manuela M. Santos, M. Pandolfo, M. Cossée, 2002, FEBS letters.

The essential nature of iron usage and regulation

J. Kaplan, D. Ward, 2013, Current Biology.

The essential nature of iron usage and regulation

J. Kaplan, D. Ward, 2013, Current Biology.

Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2

J. Kaplan, I. De Domenico, D. Ward, 2009, Proceedings of the National Academy of Sciences.

Molecular biology of iron acquisition in Saccharomyces cerevisiae

J. Kaplan, C. Askwith, D. Silva, 1996, Molecular microbiology.

Altered sterol metabolism in budding yeast affects mitochondrial iron–sulfur (Fe-S) cluster synthesis

M. Bard, Liangtao Li, J. Kaplan, 2018, The Journal of Biological Chemistry.

Characterization of Vta1p, a Class E Vps Protein in Saccharomyces cerevisiae*

J. Kaplan, D. Ward, Dinh Huynh, 2004, Journal of Biological Chemistry.

Mitochondrial Atpif1 Regulates Heme Synthesis in Developing Erythroblasts

B. Paw, B. Ebert, M. Fleming, 2011 .

Yap5 Is an Iron-Responsive Transcriptional Activator That Regulates Vacuolar Iron Storage in Yeast

Liangtao Li, J. Kaplan, D. Ward, 2007, Molecular and Cellular Biology.

Receptor-mediated endocytosis

Richard G. W. Anderson, J. Kaplan, 1983 .

Toll-like receptors mediate induction of hepcidin in mice infected with Borrelia burgdorferi.

L. Bockenstedt, J. Kushner, J. Kaplan, 2009, Blood.

Evidence for reutilization of surface receptors for α-macroglobulin · protease complexes in rabbit alveolar macrophages

J. Kaplan, 1980, Cell.

Regulation of epidermal growth factor receptor expression and growth by protein kinase C and retinoic acid in LLC-PK1 cells.

J. Kaplan, J. Kaplan, M. Hise, 1993, American journal of kidney diseases : the official journal of the National Kidney Foundation.

The Yeast Gene MSC2, a Member of the Cation Diffusion Facilitator Family, Affects the Cellular Distribution of Zinc*

Liangtao Li, J. Kaplan, 2001, The Journal of Biological Chemistry.

Mitogenic agents induce redistribution of transferrin receptors from internal pools to the cell surface.

J. Kaplan, D. Ward, D M Ward, 1986, The Biochemical journal.

Intracellular pools of transferrin receptors result from constitutive internalization of unoccupied receptors.

J. Kaplan, R. Ajioka, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Epidermal growth factor rapidly induces a redistribution of transferrin receptor pools in human fibroblasts.

H. Wiley, J. Kaplan, H S Wiley, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Second Round Robin for plasma hepcidin methods : First steps toward harmonization

M. Muckenthaler, M. Fleming, D. Ward, 2012 .

Yap5 Protein-regulated Transcription of the TYW1 Gene Protects Yeast from High Iron Toxicity*

Liangtao Li, J. Kaplan, D. Ward, 2011, The Journal of Biological Chemistry.

Identification of FRA1 and FRA2 as Genes Involved in Regulating the Yeast Iron Regulon in Response to Decreased Mitochondrial Iron-Sulfur Cluster Synthesis*

D. Winge, E. M. Adkins, A. Kumánovics, 2008, Journal of Biological Chemistry.

Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: Evidence that Yfh1p affects Fe-S cluster synthesis

J. Kaplan, O. Chen, Shawn Hemenway, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Defects in the Yeast High Affinity Iron Transport System Result in Increased Metal Sensitivity because of the Increased Expression of Transporters with a Broad Transition Metal Specificity*

Liangtao Li, J. Kaplan, 1998, The Journal of Biological Chemistry.

Fusion of intracellular membrane pools with cell surfaces of macrophages stimulated by phorbol esters and calcium ionophores

S. Buys, J. Kaplan, E. Keogh, 1984, Cell.

Cohort movement of different ligands and receptors in the intracellular endocytic pathway of alveolar macrophages.

J. Kaplan, D. Ward, D M Ward, 1989, The Journal of biological chemistry.

The Role of LIP5 and CHMP5 in Multivesicular Body Formation and HIV-1 Budding in Mammalian Cells*

W. Sundquist, J. Kaplan, D. Ward, 2005, Journal of Biological Chemistry.

Friedreich's ataxia is a mitochondrial disorder.

J. Kaplan, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Post-transcriptional Regulation of the Yeast High Affinity Iron Transport System*

B. Bartok, G. Musci, Liangtao Li, 2005, Journal of Biological Chemistry.

Genetic Dissection of a Mitochondria-Vacuole Signaling Pathway in Yeast Reveals a Link between Chronic Oxidative Stress and Vacuolar Iron Transport*

Liangtao Li, J. Kaplan, D. Ward, 2010, The Journal of Biological Chemistry.

Regulatory volume decrease in alveolar macrophages: Cation loss is not correlated with changes in membrane recycling

S. Buys, J. Kaplan, D. Ward, 1988, Journal of cellular physiology.

Regulation of ribonucleotide reductase during iron limitation.

J. Kaplan, D. Ward, Alexandra Seguin, 2011, Molecular cell.

Serum ferritin regulates blood vessel formation: A role beyond iron storage

J. Kaplan, I. De Domenico, D. Ward, 2009, Proceedings of the National Academy of Sciences.

Regulation of the transferrin-independent iron transport system in cultured cells.

J. Kaplan, A. Sturrock, I. Jordan, 1991, The Journal of biological chemistry.

Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages.

J. Pevsner, J. Kaplan, D. Ward, 2000, Molecular biology of the cell.

cise-inducedsuddencardiacdeath.Thebestcharacterizedofthesehavebeen mutationsinthecardiacCa 2+ releasechannelknownastheryanodinereceptor type2(RyR2).RyR2mutationscause"leaky"channels,resultingindiastolic Ca 2+ leakfromthesarcoplasmicreticulum(SR)thatcantriggerfatalcardiac arrhythmiasduringstress.Inth

W. Lederer, D. Terentyev, S. Györke, 2017 .

Spinocerebellar ataxias due to mitochondrial defects

J. Kaplan, 2002, Neurochemistry International.

YFH1‐mediated iron homeostasis is independent of mitochondrial respiration

J. Kaplan, O. Chen, 2001, FEBS letters.

The effects of lysozyme on anion and cation diffusion from phospholipid liposomes.

J. Kaplan, 1973, Biochimica et biophysica acta.

Molecular and clinical correlates in iron overload associated with mutations in ferroportin.

Jerry Kaplan, Elizabeta Nemeth, Tomas Ganz, 2006, Haematologica.

Iron and copper transport in yeast and its relevance to human disease.

J. Kaplan, C. Askwith, 1998, Trends in biochemical sciences.

Studies on the turnover of plasma membranes in cultured mammalian cells. II. Demonstration of heterogeneous rates of turnover for plasma membrane proteins and glycoproteins.

J. Kaplan, M. Moskowitz, 1975, Biochimica et biophysica acta.

Phorbol esters and calcium ionophores inhibit internalization and accelerate recycling of receptors in macrophages.

S. Buys, J. Kaplan, L. Gren, 1987, Journal of Biological Chemistry.

Transition metal transport in yeast.

J. Kaplan, D. Ward, Anthony Van Ho, 2002, Annual review of microbiology.

Mon1a and FCHO2 are required for maintenance of Golgi architecture

S. Morham, J. Kaplan, D. Ward, 2023, bioRxiv.

Anion diffusion across artificial lipid membranes: the effects of lysozyme on anion diffusion from phospholipid liposomes.

J. Kaplan, J. Kaplan, 1972, Biochimica et Biophysica Acta.

Gain-of-function mutations identify amino acids within transmembrane domains of the yeast vacuolar transporter Zrc1 that determine metal specificity.

J. Phillips, Liangtao Li, J. Kaplan, 2009, The Biochemical journal.

Cell contact induces an increase in pinocytotic rate in cultured epithelial cells

J. Kaplan, 1976, Nature.

Iron Acquisition and Transcriptional Regulation

Craig D. Kaplan, C. Kaplan, J. Kaplan, 2010 .

The glucose sensor Snf1 and the transcription factors Msn2 and Msn4 regulate transcription of the vacuolar iron importer gene CCC1 and iron resistance in yeast

Liangtao Li, J. Kaplan, D. Ward, 2017, The Journal of Biological Chemistry.

Recruitment of Tup1p and Cti6p regulates heme‐deficient expression of Aft1p target genes

E. M. Adkins, J. Kaplan, Emily M Kimmel, 2006, The EMBO journal.

Characterization of Two Homologous Yeast Genes That Encode Mitochondrial Iron Transporters*

Liangtao Li, J. Kaplan, 1997, The Journal of Biological Chemistry.

Effects of tunicamycin on the biosynthesis of procollagen by human fibroblasts.

J. Kaplan, M. Tanzer, F. Rowland, 1980, The Journal of biological chemistry.

Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2 (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, (3800-3805) DOI: 10.1073/pnas.0900453106)

J. Kaplan, D. Ward, I. Domenico, 2012 .

Corrigendum: Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts

B. Paw, B. Ebert, M. Fleming, 2013, Nature.

Pinocytic activity of rabbit alveolar macrophages in vitro.

J. Kaplan, M. Nielsen, 1978, Journal of the Reticuloendothelial Society.

Some Vertebrates Go with the GLO

J. Kaplan, M. Troadec, 2008, Cell.

Iron Chelation by Deferoxamine Induces Autophagy

J. Kushner, J. Kaplan, D. Ward, 2008 .

Author response: Erythropoietin signaling regulates heme biosynthesis

B. Paw, H. Lodish, S. Orkin, 2017 .

FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

B. Paw, L. Zon, H. Lodish, 2018, The Journal of Biological Chemistry.

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin.

L. Silvestri, C. Camaschella, A. Nai, 2008, Cell metabolism.

Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.

W. Sundquist, E. Morita, J. Skalicky, 2008, Developmental cell.

Induction of FPN1 transcription by MTF-1 reveals a role for ferroportin in transition metal efflux.

J. Kaplan, M. Troadec, I. De Domenico, 2010, Blood.

On the mechanism of iron sensing by IRP2: new players, new paradigms.

J. Kaplan, D. Ward, Naoko Takahashi‐Makise, 2009, Nature chemical biology.

Purification and Characterization of Fet3 Protein, a Yeast Homologue of Ceruloplasmin*

J. Kaplan, D. D. de Silva, S. Davis-Kaplan, 1997, The Journal of Biological Chemistry.

A Dominant Allele of PDR1 Alters Transition Metal Resistance in Yeast*

D. Radisky, Liangtao Li, J. Kaplan, 2003, The Journal of Biological Chemistry.

Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes

B. Paw, J. Phillips, Mitsuyo Matsumoto, 2017, The Journal of Biological Chemistry.

Effects of Tunicamycin on Procollagen Synthesis and Secretion

J. Kaplan, M. Tanzer, F. Rowland, 1979 .

Correction for De Domenico et al., Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2

J. Kaplan, D. Ward, I. Domenico, 2012, Proceedings of the National Academy of Sciences.

Mitochondrial Atpif1 regulates heme synthesis in developing erythroblasts

B. Paw, N. Danial, H. Dailey, 2012, Nature.

A Tf-independent iron transport system required for organogenesis.

J. Kaplan, M. Troadec, D. Ward, 2009, Developmental cell.

Expression of the Yeast Cation Diffusion Facilitators Mmt1 and Mmt2 Affects Mitochondrial and Cellular Iron Homeostasis

Liangtao Li, J. Kaplan, D. Ward, 2014, The Journal of Biological Chemistry.